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M

Maxim Totrov

university of georgia

50H指数
156论文数
1.2W被引数
收录论文 64
发表时间
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Identification of an Orally Efficacious Imidazo[4,5-c]pyridine-6-Carboxamide Antimalarial with a High Barrier to Resistance一种具有高耐药性屏障的口服有效咪唑[4,5-c]吡啶-6-甲酰胺类抗疟药鉴定
errJournal of Medicinal Chemistry
IF6.8
err2026-04-01
err0
PREAI
errZhou, Bo; Do Amaral, Leticia S.; Bremers, Emily K.; Haney, Reagan S.; Wardlaw, Lyric A.; Merino, Emilio F.; Li, Yuexin; Buchanan, Mairi; Baud, Delphine; Brand, Stephen; Lee, Marcus C. S.; Kelly, Jane X.; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
err分享
err收藏
Novel GPU Engines for Virtual Screening of Giga-Sized Libraries Identify Inhibitors of Challenging Targets新型GPU引擎用于虚拟筛选吉比特规模文库以识别具有挑战性靶点的抑制剂
errJournal of Chemical Information and Modeling
IF5.3
err2025-09-17
err0
PREAI
errEugene Raush; Maxim Totrov; Cody L. Hoop; Kevin M. Knowlan; Remington Bianchi; Nadya I. Tarasova
err分享
err收藏
Solvent-, enzyme-, and structural-dependence of phenyl-substituted methyl carbamate inhibition of acetylcholinesterase酚基取代甲基氨基甲酸酯对乙酰胆碱酯酶抑制作用的溶剂依赖性、酶依赖性和结构依赖性
errInsect Biochemistry and Molecular Biology
IF3.7
err2025-08-23
err0
PREAI
errDaniel R. Swale; Paul R. Carlier; Maxim Totrov; Jeffrey R. Bloomquist
err分享
err收藏
Benzo-ring modification on Malaria Box hit MMV008138: effects on antimalarial potency and microsomal stability疟疾药箱（Malaria Box）中的命中化合物MMV008138的苯环修饰：对抗疟活性和微粒体稳定性的影响
errRSC Med. Chem.
IF3.6
err2025-08-16
err0
errOAAI
errMaryam Ghavami; Haibo Li; Lixuan Liu; Joshua H. Butler; Sha Ding; Grant J. Butschek; Reagan S. Haney; R. McAlister Council-Troche; R. Justin Grams; Emilio Merino; Jennifer M Davis; Maxim Totrov; Maria B. Cassera; Paul R Carlier
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Stereospecific Resistance to N2-Acyl Tetrahydro-β-carboline Antimalarials Is Mediated by a PfMDR1 Mutation That Confers Collateral Drug Sensitivity
errACS INFECTIOUS DISEASES
IF3.8
err2025-01-14
err0
errOAAI
errBremers, Emily K.; Butler, Joshua H.; Do Amaral, Leticia S.; Merino, Emilio F.; Almolhim, Hanan; Zhou, Bo; Baptista, Rodrigo P.; Totrov, Maxim; Carlier, Paul R.; Cassera, Maria Belen
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β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling
errACS INFECTIOUS DISEASES
IF3.8
err2024-10-28
err1
PREAI
errMathew, Jopaul; Zhou, Bo; Haney, Reagan S.; Kunz, Kevin A.; Do Amaral, Leticia S.; Chowdhury, Rudraneel Roy; Butler, Joshua H.; Li, Haibo; Chakraborty, Amarraj J.; Tabassum, Anika; Bremers, Emily K.; Merino, Emilio F.; Coyle, Rachael; Lee, Marcus C. S.; Baud, Delphine; Brand, Stephen; Totrov, Maxim; Cassera, Maria Belen; Carlier, Paul R.
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Efficient Generation of Conformer Ensembles Using Internal Coordinates and a Generative Directional Graph Convolution Neural Network
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2024-04-26
err2
PREAI
errRaush, Eugene; Abagyan, Ruben; Totrov, Maxim
err分享
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In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-11-15
err19
errOAAI
errLomovskaya, Olga; Castanheira, Mariana; Lindley, Jill; Rubio-Aparicio, Debora; Nelson, Kirk; Tsivkovski, Ruslan; Sun, Dongxu; Totrov, Maxim; Loutit, Jeffery; Dudley, Michael
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Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1 (vol 14, 1271686, 2023)用免疫复合物接种调节针对HIV-1的功能性抗体的引发 (第14卷，1271686，2023)
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-11-09
err0
errOAAI
errHioe, Catarina E.; Liu, Xiaomei; Banin, Andrew N.; Heindel, Daniel W.; Klingler, Jeromine; Rao, Priyanka G.; Luo, Christina C.; Jiang, Xunqing; Pandey, Shilpi; Ordonez, Tracy; Barnette, Philip; Totrov, Maxim; Zhu, Jiang; Nadas, Arthur; Zolla-Pazner, Susan; Upadhyay, Chitra; Shen, Xiaoying; Kong, Xiang-Peng; Hessell, Ann J.
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Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1免疫复合物的疫苗接种调节针对HIV-1的功能性抗体的激发
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-10-03
err2
errOAAI
errHioe, Catarina E.; Liu, Xiaomei; Banin, Andrew N.; Heindel, Daniel W.; Klingler, Jeromine; Rao, Priyanka G.; Luo, Christina C.; Jiang, Xunqing; Pandey, Shilpi; Ordonez, Tracy; Barnette, Philip; Totrov, Maxim; Zhu, Jiang; Nadas, Arthur; Zolla-Pazner, Susan; Upadhyay, Chitra; Shen, Xiaoying; Kong, Xiang-Peng; Hessell, Ann J.
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New boronate drugs and evolving NDM-mediated beta-lactam resistance
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-09-19
err14
errOAAI
errLomovskaya, Olga; Tsivkovski, Ruslan; Totrov, Maxim; Dressel, Dana; Castanheira, Mariana; Dudley, Michael
err分享
err收藏
Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-02-24
err9
errOAAI
errAlmolhim, Hanan; Ding, Sha; Butler, Joshua H.; Bremers, Emily K.; Butschek, Grant J.; Slebodnick, Carla; Merino, Emilio F.; Rizopoulos, Zaira; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
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Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-02-23
err10
errOAAI
errMathew, Jopaul; Ding, Sha; Kunz, Kevin A.; Stacy, Emily E.; Butler, Joshua H.; Haney, Reagan S.; Merino, Emilio F.; Butschek, Grant J.; Rizopoulos, Zaira; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
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err收藏
QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2021-07-05
err33
errOAAI
errLomovskaya, Olga; Tsivkovski, Ruslan; Sun, Dongxu; Reddy, Raja; Totrov, Maxim; Hecker, Scott; Griffith, David; Loutit, Jeffery; Dudley, Michael
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In Vitro Activity of the Ultra-Broad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Meropenem against Clinical Isolates of Carbapenem-Resistant Acinetobacter baumannii
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2020-10-20
err23
errOAAI
errNelson, Kirk; Rubio-Aparicio, Debora; Tsivkovski, Ruslan; Sun, Dongxu; Totrov, Maxim; Dudley, Michael; Lomovskayaa, Olga
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err收藏
Structural Basis and Binding Kinetics of Vaborbactam in Class A β-Lactamase Inhibition
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2020-09-21
err12
errOAAI
errPemberton, Orville A.; Tsivkovski, Ruslan; Totrov, Maxim; Lomovskaya, Olga; Chen, Yu
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An HIV Vaccine Targeting the V2 Region of the HIV Envelope Induces a Highly Durable Polyfunctional Fc-Mediated Antibody Response in Rhesus Macaques针对HIV包膜V2区域的HIV疫苗在恒河猴中诱导高度持久的多功能Fc介导的抗体反应
errJOURNAL OF VIROLOGY
IF3.8
err2020-08-17
err5
errOAAI
errPowell, Rebecca L.; Weiss, Svenja; Fox, Alisa; Liu, Xiaomei; Itri, Vincenza; Jiang, Xunqing; Luo, Christina C.; Spencer, David A.; Pandey, Shilpi; Cheever, Tracy; Fuller, Deborah H.; Totrov, Maxim; Hessell, Ann J.; Haigwood, Nancy L.; Kong, Xiang-Peng; Zolla-Pazner, Susan
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Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics against Isogenic Strains Expressing Single Beta-Lactamases
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2020-05-21
err45
errOAAI
errLomovskaya, Olga; Tsivkovski, Ruslan; Nelson, Kirk; Rubio-Aparicio, Debora; Sun, Dongxu; Totrov, Maxim; Dudley, Michael N.
err分享
err收藏
Biochemical Characterization of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2020-05-21
err79
errOAAI
errTsivkovski, Ruslan; Totrov, Maxim; Lomovskaya, Olga
err分享
err收藏
Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-03-09
err140
errOAAI
errHecker, Scott J.; Reddy, K. Raja; Lomovskaya, Olga; Griffith, David C.; Rubio-Aparicio, Debora; Nelson, Kirk; Tsivkovski, Ruslan; Sun, Dongxu; Sabet, Mojgan; Tarazi, Ziad; Parkinson, Jonathan; Totrov, Maxim; Boyer, Serge H.; Glinka, Tomasz W.; Pemberton, Orville A.; Chen, Yu; Dudley, Michael N.
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研究方向

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合作学者
合作期刊
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Charles L. Brooks
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M
Michael S. Seaman
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P
Philip J. Rosenthal
H 指数: 100 · 论文数: 698
R
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J
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