Philip J. Santangelo - Publications, H-index & Citations

Philip J. Santangelo

Georgia Institute of Technology and Emory University

49H指数

180论文数

7.4K被引数

收录论文 83

发表时间

Inhaled dry powders of mRNA polyplexes prepared by thin-film freeze-drying 通过薄膜冷冻干燥制备的吸入用mRNA多聚复合物干粉

International Journal of Pharmaceutics

IF5.2

2026-08-17

PREAI

Bhupendra R. Giri; Younghun Jung; Chaeho Moon; Pramodkumar EK; Hyeyoon Jeong; Benjamin Southard; Jaehyeon Hwang; Charmy Jigneshkumar Patel; Hannah E. Peck; Donald E. Owens; Robert O. Williams; Gregory J. Davenport; Philip J. Santangelo; Chiara Zurla; Zhengrong Cui

Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection 经阴道递送具有增强广谱性和效力的mRNA编码抗体，用于SHIV/HIV保护

Nature Communications

IF15.7

2025-11-25

OAAI

Jae Yeon Joo; Peng Xiao; Susan P. John; Daryll Vanover; Hannah E. Peck; Loren E. Sasser; Deepanwita Bose; Younghun Jung; Jaehyeon Hwang; Chiara Zurla; Francois Villinger; Philip J. Santangelo

Integrated epigenetic and genetic programming of primary human T cells 整合表观遗传和遗传编程的原代人T细胞

Nature Biotechnology

IF41.7

2025-10-21

OAAI

Laine Goudy; Alvin Ha; Ashir A. Borah; Jennifer M. Umhoefer; Lauren Chow; Carinna Tran; Aidan Winters; Alexis Talbot; Rosmely Hernandez; Zhongmei Li; Sanjana Subramanya; Abolfazl Arab; Nupura Kale; Jae Hyun J. Lee; Joseph J. Muldoon; Chang Liu; Ralf Schmidt; Philip Santangelo; Julia Carnevale; Justin Eyquem; Brian R. Shy; Alex Marson; Luke A. Gilbert

Sensitizing solid tumors to CAR-mediated cytotoxicity by lipid nanoparticle delivery of synthetic antigens 通过脂质纳米颗粒递送合成抗原使实体瘤对CAR介导的细胞毒性更敏感

NATURE CANCER

IF28.5

2025-05-16

PREAI

Gamboa, Lena; Zamat, Ali H.; Thiveaud, Chloe A.; Lee, Hee Jun; Kulaksizoglu, Elif; Zha, Zizhen; Campbell, Noah S.; Chan, Ching Shen; Fabrega, Sydney; Oliver, S. Abbey; Su, Fang-Yi; Phuengkham, Hathaichanok; Vanover, Daryll; Peck, Hannah E.; Sivakumar, Anirudh; Dahotre, Shreyas N.; Harris, Adrian M.; Santangelo, Philip J.; Kwong, Gabriel A.

Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responses 纳米粒递送一种前药激活的细菌酶可诱导抗肿瘤反应

NATURE COMMUNICATIONS

IF15.7

2025-04-12

OAAI

Huayamares, Sebastian G.; Lian, Liming; Rab, Regina; Hou, Yuning; Radmand, Afsane; Kim, Hyejin; Zenhausern, Ryan; Achyut, Bhagelu R.; Ross, Melissa Gilbert; Lokugamage, Melissa P.; Loughrey, David; Peck, Hannah E.; Echeverri, Elisa Schrader; Sanchez, Alejandro J. Da Silva; Shajii, Aram; Li, Andrea; Tiegreen, Karen E.; Santangelo, Philip J.; Sorscher, Eric J.; Dahlman, James E.

Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys 脂质纳米颗粒介导的恒河猴CD34细胞的mRNA传递

NATURE BIOTECHNOLOGY

IF41.7

2024-11-22

PREAI

Kim, Hyejin; Zenhausern, Ryan; Gentry, Kara; Lian, Liming; Huayamares, Sebastian G.; Radmand, Afsane; Loughrey, David; Podilapu, Ananda R.; Hatit, Marine Z. C.; Ni, Huanzhen; Li, Andrea; Shajii, Aram; Peck, Hannah E.; Han, Keyi; Hua, Xuanwen; Jia, Shu; Martinez, Michele; Lee, Charles; Santangelo, Philip J.; Tarantal, Alice; Dahlman, James E.

Lipid nanoparticles deliver mRNA to the blood-brain barrier 脂质纳米颗粒将mRNA递送至血脑屏障

NANO RESEARCH

IF9

2024-08-01

PREAI

Kuzminich, Yanina; Shakked, Avraham; Calkins, Randi; Rudden, Sebastian; Jones, Camille; Doan, Jessie; Jang, Bora; Echeverri, Elisa Schrader; Zenhausern, Ryan; Lian, Liming; Loughrey, David; Peck, Hannah E.; Wiese, Rachelle; Koveal, Dorothy; Santangelo, Philip J.; Dahlman, James E.

mRNA-encoded Cas13 treatment of Influenza via site-specific degradation of genomic RNA

PLOS PATHOGENS

IF4.9

2024-07-05

OAAI

Chaves, Lorena C. S.; Orr-Burks, Nichole; Vanover, Daryll; Mosur, Varun V.; Hosking, Sarah R.; Kumar, Pramod E. K.; Jeong, Hyeyoon; Jung, Younghun; Assumpcao, Jose A. F.; Peck, Hannah E.; Nelson, Sarah L.; Burke, Kaitlyn N.; Garrison, McKinzie A.; Arthur, Robert A.; Claussen, Henry; Heaton, Nicholas S.; Lafontaine, Eric R.; Hogan, Robert J.; Zurla, Chiara; Santangelo, Philip J.

Transient pacing in pigs with complete heart block via myocardial injection of mRNA coding for the T-box transcription factor 18

NATURE BIOMEDICAL ENGINEERING

IF26.6

2024-05-02

OAAI

Wolfson, David W.; Kim, Nam Kyun; Lee, Ki Hong; Beyersdorf, Jared P.; Langberg, Jonathan J.; Fernandez, Natasha; Choi, Dahim; Zureick, Nadine; Kim, Tae Yun; Bae, Seongho; Gu, Jin-Mo; Kirschman, Jonathan L.; Fan, Jinqi; Sheng, Christina Y.; Sen, Danielle Gottlieb; Mettler, Bret; Sung, Jung Hoon; Yoon, Young-sup; Park, Sung-Jin; Santangelo, Philip J.; Cho, Hee Cheol

Substituting Poly(ethylene glycol) Lipids with Poly(2-ethyl-2-oxazoline) Lipids Improves Lipid Nanoparticle Repeat Dosing

ADVANCED HEALTHCARE MATERIALS

IF9.6

2024-03-10

PREAI

Sanchez, Alejandro J. Da Silva; Loughrey, David; Echeverri, Elisa Schrader; Huayamares, Sebastian G.; Radmand, Afsane; Paunovska, Kalina; Hatit, Marine; Tiegreen, Karen E.; Santangelo, Philip J.; Dahlman, James E.

Platform-Specific Fc N-Glycan Profiles of an Antisperm Antibody

ANTIBODIES

IF2.7

2024-03-06

OAAI

Nador, Ellena; Xia, Chaoshuang; Santangelo, Philip J.; Whaley, Kevin J.; Costello, Catherine E.; Anderson, Deborah J.

Cationic cholesterol- dependent LNP delivery to lung stem cells, the liver, and heart

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-03-04

OAAI

Radmand, Afsane; Kim, Hyejin; Beyersdorf, Jared; Dobrowolski, Curtis N.; Zenhausern, Ryan; Paunovska, Kalina; Huayamares, Sebastian G.; Hua, Xuanwen; Han, Keyi; Loughrey, David; Hatit, Marine Z. C.; Del Cid, Ada; Ni, Huanzhen; Shajii, Aram; Li, Andrea; Muralidharan, Abinaya; Peck, Hannah E.; Tiegreen, Karen E.; Jia, Shu; Santangelo, Philip J.; Dahlman, James E.

Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo (vol 7, e162290, 2022)

JCI INSIGHT

IF6.1

2023-11-22

OAAI

Samer, Sadia; Thomas, Yanique; Arainga, Mariluz; Carter, Crystal; Shirreff, Lisa M.; Arif, Muhammad S.; Avita, Juan M.; Frank, Ines; McRaven, Michael D.; Thuruthiyil, Christopher T.; Heybeli, Veli B.; Anderson, Meegan R.; Owen, Benjamin; Gaisin, Arsen; Bose, Deepanwita; Simons, Lacy M.; Hultquist, Judd F.; Arthos, James; Cicala, Claudia; Sereti, Irini; Santangelo, Philip J.; Lorenzo-Redondo, Ramon; Hope, Thomas J.; Villinger, Francois J.; Martinelli, Elena

A direct contact pig influenza challenge model for assessing protective efficacy of monoclonal antibodies

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-10-27

OAAI

Mcnee, Adam; Vanover, Daryll; Rijal, Pramila; Paudyal, Basudev; Lean, Fabian Z. X.; Macloughlin, Ronan; Nunez, Alejandro; Townsend, Alain; Santangelo, Philip J.; Tchilian, Elma

The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo 肺靶向脂质纳米粒的体内转录反应

NANO LETTERS

IF9.1

2023-01-26

OAAI

Radmand, Afsane; Lokugamage, Melissa P.; Kim, Hyejin; Dobrowolski, Curtis; Zenhausern, Ryan; Loughrey, David; Huayamares, Sebastian G.; Hatit, Marine Z. C.; Ni, Huanzhen; Del Cid, Ada; Sanchez, Alejandro J. Da Silva; Paunovska, Kalina; Echeverri, Elisa Schrader; Shajii, Aram; Peck, Hannah; Santangelo, Philip J.; Dahlman, James E.

The Extent to Which Lipid Nanoparticles Require Apolipoprotein E and Low-Density Lipoprotein Receptor for Delivery Changes with Ionizable Lipid Structure 脂质纳米颗粒需要载脂蛋白E和低密度脂蛋白受体递送的程度随可电离脂质结构的变化而变化

NANO LETTERS

IF9.1

2022-12-15

PREAI

Paunovska, Kalina; Da Silva Sanchez, Alejandro J.; Lokugamage, Melissa P.; Loughrey, David; Echeverri, Elisa Schrader; Cristian, Ana; Hatit, Marine Z. C.; Santangelo, Philip J.; Zhao, Kun; Dahlman, James E.

Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung

NATURE MATERIALS

IF38.5

2022-11-28

OAAI

Rotolo, Laura; Vanover, Daryll; Bruno, Nicholas C.; Peck, Hannah E.; Zurla, Chiara; Murray, Jackelyn; Noel, Richard K.; O'Farrell, Laura; Arainga, Mariluz; Orr-Burks, Nichole; Joo, Jae Yeon; Chaves, Lorena C. S.; Jung, Younghun; Beyersdorf, Jared; Gumber, Sanjeev; Guerrero-Ferreira, Ricardo; Cornejo, Santiago; Thoresen, Merrilee; Olivier, Alicia K.; Kuo, Katie M.; Gumbart, James C.; Woolums, Amelia R.; Villinger, Francois; Lafontaine, Eric R.; Hogan, Robert J.; Finn, M. G.; Santangelo, Philip J.

Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo

JCI INSIGHT

IF6.1

2022-11-08

OAAI

Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection

ADVANCED SCIENCE

IF14.1

2022-10-31

OAAI

Vanover, Daryll; Zurla, Chiara; Peck, Hannah E.; Orr-Burks, Nichole; Joo, Jae Yeon; Murray, Jackelyn; Holladay, Nathan; Hobbs, Ryan A.; Jung, Younghun; Chaves, Lorena C. S.; Rotolo, Laura; Lifland, Aaron W.; Olivier, Alicia K.; Li, Dapeng; Saunders, Kevin O.; Sempowski, Gregory D.; Crowe, James E., Jr.; Haynes, Barton F.; Lafontaine, Eric R.; Hogan, Robert J.; Santangelo, Philip J.

p38MAPK guards the integrity of endosomal compartments through regulating necrotic death

SCIENTIFIC REPORTS

IF3.9

2022-09-29

OAAI

Yao, Jia; Atasheva, Svetlana; Toy, Randall; Blanchard, Emmeline L.; Santangelo, Philip J.; Roy, Krishnendu; Mocarski, Edward S.; Shayakhmetov, Dmitry M.

研究方向