Ángel Ramírez-Fernández

Perelman School of Medicine

H指数:7

被引数:449

个人简介

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A modular γδ TCR-T platform combining KRAS pMHC targeting with re-dosable mRNA engager redirection

模块化 γ δ tcr-t平台，将KRAS pMHC靶向与可重复剂量的mRNA接合器重定向相结合

Journal of Hematology & Oncology

IF40.4

2026-07-300

Ángel Ramírez-Fernández; Adham S. Bear; Elahe Kamali; Robert Bartoszek; Matthew Ho; Gregory M. Chen; Devin Dersh; Laura Córdoba-Espejo; Jiageng Liu; Mosha Deng; Miriam Velasco-Sidro; Ankita Jain; Julia Han Noll; Caitlin R Hopkins; Owen Koucky; Janna Minehart; Alexander J. Dimitri; Erik Williams; Maya Lavorando; Alejandro Segura-Tudela; John Scholler; Julie Barber-Rotenberg; Julie K. Jadlowsky; Daniel J. Powell; Anne Chew; Vanessa E. Gonzalez; Donald L. Siegel; Bruce L. Levine; Michael T. Lotze; Carl H. June; James L. Riley; Robert H. Vonderheide; Friederike Herbst; Joseph A. Fraietta

Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer

泛血液学癌症对嵌合抗原受体 (CAR) T细胞治疗反应的预测生物标志物

Nature Biomedical Engineering

IF26.6

2026-03-090

PRE

Gregory M. Chen; Ankita Jain; David T. Gering; Javier Satulovsky; Sarbani Datta; Peng Lai; Jayashree Karar; Vanessa E. Gonzalez; Kathleen Alexander; Anne Chew; Julie K. Jadlowsky; Marco Ruella; Luca Paruzzo; Kevin R. Amses; Andrew J. Rech; Edward A. Stadtmauer; Noelle V. Frey; Elizabeth O. Hexner; David L. Porter; Adam D. Cohen; Saar I. Gill; Alfred L. Garfall; Stephen J. Schuster; Kelvin C. Mo; Samantha I. Liang; Marko Spasic; Bruce L. Levine; Don L. Siegel; Angel Ramírez-Fernández; Christopher R. Cabanski; EnJun Yang; Crystal L. Mackall; Frederic D. Bushman; Zinaida Good; E. John Wherry; Carl H. June; Joseph A. Fraietta

CD4+ T cells mediate CAR-T cell-associated immune-related adverse events after BCMA CAR-T cell therapy

CD4 T细胞介导BCMA car-t细胞治疗后car-t细胞相关的免疫相关不良事件

Nature Medicine

IF50

2026-01-150

PRE

Matthew Ho; Luca Paruzzo; Julia Han Noll; Federico Stella; Pooja Devi; Sonia Ndeupen; Yael A. Day; Gregory M. Chen; Ivan J. Cohen; Angel Ramirez-Fernandez; Adam Waxman; Shivani Kapur; Fang Chen; Rong Xu; Andrew Huff; Danuta Jarocha; Vrutti Patel; Audrey C. Bochi-Layec; Ranjani Ramasubramanian; Shan Liu; Riemke Bouvier; Vitor B. de Souza; Heta Patel; Ziyu Li; Alberto Carturan; Peter Michener; Caitlin R. Hopkins; Owen Koucky; Janna Minehart; Alex Dimitri; Neel R. Nabar; Zainul S. Hasanali; Bryan T. Ciccarelli; Putzer Hung; Erik Williams; Robert Bartoszek; Maya Lavorando; Suyash Mohan; Vanessa E. Gonzalez; Patrizia Porazzi; Vijay G. Bhoj; Sokratis A. Apostolidis; Dan T. Vogl; David L. Porter; John Scholler; Caroline Diorio; Aoife M. Roche; John K. Everett; Frederic D. Bushman; Katherine L. Nathanson; Edward A. Stadtmauer; Sandra P. Susanibar-Adaniya; Alfred L. Garfall; Marco Ruella; Adam D. Cohen; Joseph A. Fraietta

mRNA-engineered T lymphocytes secreting bispecific T cell engagers with therapeutic potential in solid tumors

mRNA工程化T淋巴细胞分泌具有实体瘤治疗潜力的双特异性T细胞接合物

Frontiers in Immunology

IF5.9

2025-11-180

OAAI

CCR5-targeted allogeneic gamma–delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy

CCR5靶向的异基因γ-δ CD19嵌合抗原受体T细胞用于HIV相关B细胞恶性免疫治疗

Nature Biomedical Engineering

IF26.6

2025-10-210

PRE

CD22 CAR-T cells secreting CD19 T-cell engagers for improved control of B-cell acute lymphoblastic leukemia progression

分泌CD19 T细胞结合剂的CD22 CAR-T细胞，用于改善B细胞急性淋巴细胞白血病进展的控制

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2025-04-300

Arroyo-Rodenas, Javier; Falgas, Aida; Diez-Alonso, Laura; Martinez-Moreno, Alba; Roca-Ho, Heleia; Gil-Etayo, Francisco J.; Perez-Pons, Alba; Aguilar-Sopena, Oscar; Velasco-Sidro, Miriam; Gomez-Rosel, Marina; Jimenez-Matias, Beatriz; Munoz-Sanchez, Guillermo; Pacheco, Yedra; Bravo-Martin, Clara; Ramirez-Fernandez, Angel; Jimenez-Reinoso, Anais; Gonzalez-Navarro, Europa Azucena; Juan, Manel; Orfao, Alberto; Blanco, Belen; Roda-Navarro, Pedro; Bueno, Clara; Menendez, Pablo; Alvarez-Vallina, Luis

Dual-targeted STAb-T cells secreting BCMA and CD19 T cell engagers for improved control of haematological cancers

分泌BCMA和CD19 T细胞接合器的双靶向stab-t细胞可改善对血液癌症的控制

ONCOIMMUNOLOGY

IF6.3

2024-12-260

CD4+ tumor-infiltrating lymphocytes secreting T cell-engagers induce regression of autologous patient-derived non-small cell lung cancer xenografts

ONCOIMMUNOLOGY

IF6.3

2024-08-271

Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo

分泌抗BCMA T细胞衔接剂的工程化T细胞控制多发性骨髓瘤并促进体内免疫记忆

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-02-145

PRE

Diez-Alonso, Laura; Falgas, Aida; Arroyo-Rodenas, Javier; Romencin, Paola A.; Martinez, Alba; Gomez-Rosel, Marina; Blanco, Belen; Jimenez-Reinoso, Anais; Mayado, Andrea; Perez-Pons, Alba; Aguilar-Sopena, Oscar; Ramirez-Fernandez, Angel; Segura-Tudela, Alejandro; Perez-Amill, Lorena; Tapia-Galisteo, Antonio; Dominguez-Alonso, Carmen; Rubio-Perez, Laura; Jara, Maria; Sole, Francesc; Hangiu, Oana; Almagro, Laura; Albitre, Angela; Penela, Petronila; Sanz, Laura; Anguita, Eduardo; Valeri, Antonio; Garcia-Ortiz, Almudena; Rio, Paula; Juan, Manel; Martinez-Lopez, Joaquin; Roda-Navarro, Pedro; Martin-Antonio, Beatriz; Orfao, Alberto; Menendez, Pablo; Bueno, Clara; alvarez-Vallina, Luis

A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response

ONCOIMMUNOLOGY

IF6.3

2023-04-2410