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J

Joseph A. Fraietta

Abramson Cancer Center
H指数:45
被引数:1.5万

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Programmable CAR-engaging particles rewire human CAR T-cell signaling for sustainable ex vivo expansion

可编程CAR-结合颗粒重编程人CAR T细胞信号以实现可持续体外扩增

Nature Communications
IF15.7
2026-09-070
OAAI
Qinghe Zeng; Landon Flemming; Yuanzhou Chen; Thomas Mazumder; Heinz Hammerlindl; Greg M. Allen; Ricardo Almeida; Jasper Z. Williams; Rogelio A. Hernández-López; Ania-Ariadna Baetica; Sara E. Meyer; Joseph A. Fraietta; Justin Eyquem; Chun J. Ye; Wendell A. Lim; Qizhi Tang; Tejal A. Desai; Xiao Huang
Publisher Correction: Decade-long persistence of CD19 CAR T cells in B cell lymphomas

出版更正：CD19 CAR T细胞在B细胞淋巴瘤中的十年持久性

Nature Medicine
IF50
2026-08-260
OAAI
Luca Paruzzo; Emeline R. Chong; Elise A. Chong; Zhixuan Zheng; Puneeth Guruprasad; Daniel J. Landsburg; Sunita D. Nasta; Federico Stella; Ranjani Ramasubramanian; Vitor B. de Souza; Mohannad H. Alkhatib; Matthew Ho; Antonio Imparato; Gregory M. Chen; Don L. Siegel; Gabriela Plesa; Anlan Dai; Shane Mackey; Priyamvada Das; Peter Michener; Julie Jadlowsky; Frederic D. Bushman; Vrutti Patel; Alberto Carturan; Ellen B. Napier; Vanessa E. Gonzalez; Danuta Jarocha; Rong Xu; Bruce L. Levine; Patrizia Porazzi; Noelle Frey; David L. Porter; Jakub Svoboda; Joseph A. Fraietta; Carl H. June; Stephen J. Schuster; Marco Ruella
A modular γδ TCR-T platform combining KRAS pMHC targeting with re-dosable mRNA engager redirection

模块化 γ δ tcr-t平台，将KRAS pMHC靶向与可重复剂量的mRNA接合器重定向相结合

Journal of Hematology & Oncology
IF40.4
2026-07-300
OA
Ángel Ramírez-Fernández; Adham S. Bear; Elahe Kamali; Robert Bartoszek; Matthew Ho; Gregory M. Chen; Devin Dersh; Laura Córdoba-Espejo; Jiageng Liu; Mosha Deng; Miriam Velasco-Sidro; Ankita Jain; Julia Han Noll; Caitlin R Hopkins; Owen Koucky; Janna Minehart; Alexander J. Dimitri; Erik Williams; Maya Lavorando; Alejandro Segura-Tudela; John Scholler; Julie Barber-Rotenberg; Julie K. Jadlowsky; Daniel J. Powell; Anne Chew; Vanessa E. Gonzalez; Donald L. Siegel; Bruce L. Levine; Michael T. Lotze; Carl H. June; James L. Riley; Robert H. Vonderheide; Friederike Herbst; Joseph A. Fraietta
Naïve CD4+ T-cells and disease status at CART infusion correlate with clinical outcomes in real-world large B-cell lymphoma patients receiving second-line CAR T therapy

初始CD4+ T细胞和CART输注时的疾病状态与接受二线CAR T疗法的大B细胞淋巴瘤患者的真实世界临床结局相关

Nature Communications
IF15.7
2026-05-150
OAAI
Michael Schneider; Luca Paruzzo; Federico Stella; Julia Han Noll; Matthew Ho; Victor Babatunde; Bianca Ho; Pooja Devi; Elise A. Chong; Stefan K. Barta; Sunita D. Nasta; Jakub Svoboda; Jordan Carter; Michael R. Cook; Nasheed M. Hossain; Colin J. Thomas; Vrutti Patel; Vitor B. de Souza; Mohannad H. Alkhatib; Ziyu Li; Melody Tan; Peter Michener; Puneeth Guruprasad; Antonio Imparato; Alberto Carturan; Patrizia Porazzi; Joseph A. Fraietta; Stephen J. Schuster; Ivan Maillard; Marco Ruella; Daniel J. Landsburg
Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer

泛血液学癌症对嵌合抗原受体 (CAR) T细胞治疗反应的预测生物标志物

Nature Biomedical Engineering
IF26.6
2026-03-090
PRE
Gregory M. Chen; Ankita Jain; David T. Gering; Javier Satulovsky; Sarbani Datta; Peng Lai; Jayashree Karar; Vanessa E. Gonzalez; Kathleen Alexander; Anne Chew; Julie K. Jadlowsky; Marco Ruella; Luca Paruzzo; Kevin R. Amses; Andrew J. Rech; Edward A. Stadtmauer; Noelle V. Frey; Elizabeth O. Hexner; David L. Porter; Adam D. Cohen; Saar I. Gill; Alfred L. Garfall; Stephen J. Schuster; Kelvin C. Mo; Samantha I. Liang; Marko Spasic; Bruce L. Levine; Don L. Siegel; Angel Ramírez-Fernández; Christopher R. Cabanski; EnJun Yang; Crystal L. Mackall; Frederic D. Bushman; Zinaida Good; E. John Wherry; Carl H. June; Joseph A. Fraietta
CD4+ T cells mediate CAR-T cell-associated immune-related adverse events after BCMA CAR-T cell therapy

CD4 T细胞介导BCMA car-t细胞治疗后car-t细胞相关的免疫相关不良事件

Nature Medicine
IF50
2026-01-150
PRE
Matthew Ho; Luca Paruzzo; Julia Han Noll; Federico Stella; Pooja Devi; Sonia Ndeupen; Yael A. Day; Gregory M. Chen; Ivan J. Cohen; Angel Ramirez-Fernandez; Adam Waxman; Shivani Kapur; Fang Chen; Rong Xu; Andrew Huff; Danuta Jarocha; Vrutti Patel; Audrey C. Bochi-Layec; Ranjani Ramasubramanian; Shan Liu; Riemke Bouvier; Vitor B. de Souza; Heta Patel; Ziyu Li; Alberto Carturan; Peter Michener; Caitlin R. Hopkins; Owen Koucky; Janna Minehart; Alex Dimitri; Neel R. Nabar; Zainul S. Hasanali; Bryan T. Ciccarelli; Putzer Hung; Erik Williams; Robert Bartoszek; Maya Lavorando; Suyash Mohan; Vanessa E. Gonzalez; Patrizia Porazzi; Vijay G. Bhoj; Sokratis A. Apostolidis; Dan T. Vogl; David L. Porter; John Scholler; Caroline Diorio; Aoife M. Roche; John K. Everett; Frederic D. Bushman; Katherine L. Nathanson; Edward A. Stadtmauer; Sandra P. Susanibar-Adaniya; Alfred L. Garfall; Marco Ruella; Adam D. Cohen; Joseph A. Fraietta
Outcomes of relapse after teclistamab therapy in multiple myeloma

接受特昔利珠单抗治疗后多发性骨髓瘤复发的结局

Blood Cancer Journal
IF11.6
2025-11-050
OAAI
Kyle L. Yu; Matthew Ho; Luca Paruzzo; Federico Stella; Heta Patel; Zainul S. Hasanali; Shivani Kapur; Adam J. Waxman; Dan T. Vogl; Edward A. Stadtmauer; Joseph A. Fraietta; Marco Ruella; Adam D. Cohen; Alfred L. Garfall; Sandra Susanibar-Adaniya
Immune remodeling in CSF and tumor predicts response to CAR T therapy in glioblastoma

脑脊液和肿瘤中的免疫重塑预测胶质母细胞瘤对CAR T疗法的反应

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Chafamo, Daniel; Freeburg, Nelson; Gopikrishna, Gayathri Konanur; Peng, Jacqueline; Lamrani, Lamia; Hicks, Kelly; Ekwegbara, Christina; Bawden, Emma; Waterfall, Joshua; Fuentealba, Jaime; Alcantara, Marion; Barrett, David; Macia, Camilla; Yin, Melinda; Carpenter, Erica; Wherry, Edward; Amigorena, Sebastian; Fraietta, Joseph; Nasrallah, MacLean; Bagley, Stephen; O'rourke, Donald; Binder, Zev; Alanio, Cecile; Silverbush, Dana
CCR5-targeted allogeneic gamma–delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy

CCR5靶向的异基因γ-δ CD19嵌合抗原受体T细胞用于HIV相关B细胞恶性免疫治疗

Nature Biomedical Engineering
IF26.6
2025-10-210
PRE
Ángel Ramírez-Fernández; Alexander J. Dimitri; Fang Chen; Robert Bartoszek; Gregory M. Chen; Laura Córdoba-Espejo; Yuqi Zhou; Yun-hsin Tang; Chien-Ting Lin; Reyes Acosta; John Scholler; Guido Ghilardi; Patrizia Porazzi; Mireia Pellicer; Núria Profitós-Pelejà; Stefan K. Barta; Anne Chew; Julie K. Jadlowsky; Vanessa E. Gonzalez; Donald L. Siegel; Bruce L. Levine; Gaël Roué; Marco Ruella; Michael T. Lotze; Carl H. June; James L. Riley; Joseph A. Fraietta
Clinical and molecular dissection of CAR T cell resistance in pancreatic cancer

胰腺癌中CAR T细胞耐药性的临床与分子解析

Cell Reports Medicine
IF10.6
2025-08-180
OAAI
M. Angela Aznar; Charly R. Good; Julie S. Barber-Rotenberg; Sangya Agarwal; Wesley Wilson; Alex Watts; Zhen Zhang; Donna Gonzales; Greg Donahue; Wei-Ting Hwang; Austin K. Rennels; Andrew J. Rech; Shunichiro Kuramitsu; Hua Huang; Karl M. Glastad; Katherine A. Alexander; Gabriela Plesa; Emily Dowd; Andrea Brennan; Donald L. Siegel; Janos Tanyi; Andrew Haas; Drew A. Torigian; Gregory Nadolski; Vanessa E. Gonzalez; Elizabeth O. Hexner; Joseph A. Fraietta; Julie K. Jadlowsky; Regina M. Young; Shelley L. Berger; Carl H. June; Mark H. O’Hara
TET2 regulates early and late transitions in exhausted CD8+ T cell differentiation and limits CAR T cell function
SCIENCE ADVANCES
IF12.5
2024-11-150
OAAI
Dimitri, Alexander J.; Baxter, Amy E.; Chen, Gregory M.; Hopkins, Caitlin R.; Rouin, Geoffrey T.; Huang, Hua; Kong, Weimin; Holliday, Christopher H.; Wiebking, Volker; Bartoszek, Robert; Drury, Sydney; Dalton, Katherine; Koucky, Owen M.; Chen, Zeyu; Giles, Josephine R.; Dils, Alexander T.; Jung, In-Young; O'Connor, Roddy; Collins, Sierra; Everett, John K.; Amses, Kevin; Sherrill-Mix, Scott; Chandra, Aditi; Goldman, Naomi; Vahedi, Golnaz; Jadlowsky, Julie K.; Young, Regina M.; Melenhorst, Jan Joseph; Maude, Shannon L.; Levine, Bruce L.; Frey, Noelle V.; Berger, Shelley L.; Grupp, Stephan A.; Porter, David L.; Herbst, Friederike; Porteus, Matthew H.; Carty, Shannon A.; Bushman, Frederic D.; Weber, Evan W.; Wherry, E. John; Jordan, Martha S.; Fraietta, Joseph A.
Efficacy and Safety of Anti-CDI9 and Anti-BCMA Chimeric Antigen Receptor (CAR) T-Cell Therapies in Patients with Autoimmune Disease and Lymphoma or Myeloma

抗CDI9和抗BCMA嵌合抗原受体（CAR）T细胞疗法在自身免疫性疾病、淋巴瘤或骨髓瘤患者中的疗效与安全性

BLOOD
IF23.1
2024-11-050
PRE
Paruzzo, Luca; Bouvier, Riemke; Ghilardi, Guido; Fardella, Eugenio; Fulmer, Bria; Cohen, Ivan J.; Chong, Elise A.; Svoboda, Jakub; Nasta, Sunita D.; Landsburg, Daniel J.; Patel, Vrutti; Ziyu, Li; Pajarillo, Raymone; Waxman, Adam; Cohen, Adam D.; Vogl, Dan T.; Barta, Stefan K.; Porazzi, Patrizia; Fraietta, Joseph A.; Bhoj, Vijay; Garfall, Alfred L.; Stadtmauer, Edward A.; Schuster, Stephen J.; Carter, Jordan S.; Apostolidis, Sokratis A.; Susanibar-Adaniya, Sandra; Ruella, Marco
Cytokine-mediated CAR T therapy resistance in AML

细胞因子介导的AML car-t治疗耐药

NATURE MEDICINE
IF50
2024-09-272
PRE
Bhagwat, Anand S.; Torres, Leonel; Shestova, Olga; Shestov, Maksim; Mellors, Patrick W.; Fisher, Han R.; Farooki, Saamia N.; Frost, Benjamin F.; Loken, Michael R.; Gaymon, Avery L.; Frazee, Diane; Rogal, Walter; Frey, Noelle; Hexner, Elizabeth O.; Luger, Selina M.; Loren, Alison W.; Martin, Mary Ellen; Mccurdy, Shannon R.; Perl, Alexander E.; Stadtmauer, Edward A.; Brogdon, Jennifer L.; Fraietta, Joseph A.; Hwang, Wei-Ting; Siegel, Don L.; Plesa, Gabriela; Aplenc, Richard; Porter, David L.; June, Carl H.; Gill, Saar I.
Reinfusion of CD19 CAR T cells for relapse prevention and treatment in children with acute lymphoblastic leukemia

CD19 CAR T细胞回输预防和治疗儿童急性淋巴细胞白血病复发

BLOOD ADVANCES
IF7.1
2024-04-291
OAAI
Myers, Regina M.; Devine, Kaitlin; Li, Yimei; Lawrence, Sophie; Leahy, Allison Barz; Liu, Hongyan; Vernau, Lauren; Callahan, Colleen; Baniewicz, Diane; Kadauke, Stephan; McGuire, Regina; Wertheim, Gerald B.; Kulikovskaya, Irina; Gonzalez, Vanessa E.; Fraietta, Joseph A.; DiNofia, Amanda M.; Hunger, Stephen P.; Rheingold, Susan R.; Aplenc, Richard; June, Carl H.; Grupp, Stephan A.; Wray, Lisa; Maude, Shannon L.

研究方向

暂未获取到该数据
C
Carl H. June
H 指数:177论文数:1,428被引数:14.4万
B
Bruce L. Levine
H 指数:102论文数:550被引数:6.6万
S
Simon F. Lacey
H 指数:75论文数:382被引数:3.8万
J
Julie K. Jadlowsky
H 指数:19论文数:68被引数:3,759
J
J. Joseph Melenhorst
H 指数:60论文数:294被引数:2.9万
G
Gabriela Plesa
H 指数:40论文数:245被引数:1.3万
V
Vanessa Gonzalez
H 指数:24论文数:138被引数:1.2万
M
Megan M. Davis
H 指数:27论文数:88被引数:7,962
M
Marco Ruella
H 指数:48论文数:344被引数:1.3万
I
Irina Kulikovskaya
H 指数:32论文数:124被引数:1.0万