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J

Julie K. Jadlowsky

University of Pennsylvania
H指数:19
被引数:3,761

个人简介

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Publisher Correction: Decade-long persistence of CD19 CAR T cells in B cell lymphomas

出版更正：CD19 CAR T细胞在B细胞淋巴瘤中的十年持久性

Nature Medicine
IF50
2026-08-260
OAAI
Luca Paruzzo; Emeline R. Chong; Elise A. Chong; Zhixuan Zheng; Puneeth Guruprasad; Daniel J. Landsburg; Sunita D. Nasta; Federico Stella; Ranjani Ramasubramanian; Vitor B. de Souza; Mohannad H. Alkhatib; Matthew Ho; Antonio Imparato; Gregory M. Chen; Don L. Siegel; Gabriela Plesa; Anlan Dai; Shane Mackey; Priyamvada Das; Peter Michener; Julie Jadlowsky; Frederic D. Bushman; Vrutti Patel; Alberto Carturan; Ellen B. Napier; Vanessa E. Gonzalez; Danuta Jarocha; Rong Xu; Bruce L. Levine; Patrizia Porazzi; Noelle Frey; David L. Porter; Jakub Svoboda; Joseph A. Fraietta; Carl H. June; Stephen J. Schuster; Marco Ruella
Decade-long persistence of CD19 CAR T cells in B cell lymphomas

CD19 CAR T细胞在B细胞淋巴瘤中的十年持续性

Nature Medicine
IF50
2026-08-100
OA
Luca Paruzzo; Emeline R. Chong; Elise A. Chong; Zhixuan Zheng; Puneeth Guruprasad; Daniel J. Landsburg; Sunita D. Nasta; Federico Stella; Ranjani Ramasubramanian; Vitor B. de Souza; Mohannad H. Alkhatib; Matthew Ho; Antonio Imparato; Gregory M. Chen; Don L. Siegel; Gabriela Plesa; Anlan Dai; Shane Mackey; Priyamvada Das; Peter Michener; Julie Jadlowsky; Frederic D. Bushman; Vrutti Patel; Alberto Carturan; Ellen B. Napier; Vanessa E. Gonzalez; Danuta Jarocha; Rong Xu; Bruce L. Levine; Patrizia Porazzi; Noelle Frey; David L. Porter; Jakub Svoboda; Joseph A. Fraietta; Carl H. June; Stephen J. Schuster; Marco Ruella
A modular γδ TCR-T platform combining KRAS pMHC targeting with re-dosable mRNA engager redirection

模块化 γ δ tcr-t平台，将KRAS pMHC靶向与可重复剂量的mRNA接合器重定向相结合

Journal of Hematology & Oncology
IF40.4
2026-07-300
OA
Ángel Ramírez-Fernández; Adham S. Bear; Elahe Kamali; Robert Bartoszek; Matthew Ho; Gregory M. Chen; Devin Dersh; Laura Córdoba-Espejo; Jiageng Liu; Mosha Deng; Miriam Velasco-Sidro; Ankita Jain; Julia Han Noll; Caitlin R Hopkins; Owen Koucky; Janna Minehart; Alexander J. Dimitri; Erik Williams; Maya Lavorando; Alejandro Segura-Tudela; John Scholler; Julie Barber-Rotenberg; Julie K. Jadlowsky; Daniel J. Powell; Anne Chew; Vanessa E. Gonzalez; Donald L. Siegel; Bruce L. Levine; Michael T. Lotze; Carl H. June; James L. Riley; Robert H. Vonderheide; Friederike Herbst; Joseph A. Fraietta
Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer

泛血液学癌症对嵌合抗原受体 (CAR) T细胞治疗反应的预测生物标志物

Nature Biomedical Engineering
IF26.6
2026-03-090
PRE
Gregory M. Chen; Ankita Jain; David T. Gering; Javier Satulovsky; Sarbani Datta; Peng Lai; Jayashree Karar; Vanessa E. Gonzalez; Kathleen Alexander; Anne Chew; Julie K. Jadlowsky; Marco Ruella; Luca Paruzzo; Kevin R. Amses; Andrew J. Rech; Edward A. Stadtmauer; Noelle V. Frey; Elizabeth O. Hexner; David L. Porter; Adam D. Cohen; Saar I. Gill; Alfred L. Garfall; Stephen J. Schuster; Kelvin C. Mo; Samantha I. Liang; Marko Spasic; Bruce L. Levine; Don L. Siegel; Angel Ramírez-Fernández; Christopher R. Cabanski; EnJun Yang; Crystal L. Mackall; Frederic D. Bushman; Zinaida Good; E. John Wherry; Carl H. June; Joseph A. Fraietta
Clinical Trial Results Provide the Rationale to Protect Dual HIV-specific T Cells with a Signaling-Defective HIV Fusion Inhibitor

临床 trial 结果提供了保护 dual HIV-specific T cells 的 rationale，其方法是使用一种 signaling-defective HIV fusion inhibitor。

Molecular Therapy
IF12
2026-01-100
PRE
Pablo Tebas; Julie K. Jadlowsky; Yuqi Zhou; M.Betina Pampena; George J. Leslie; Nan Liu; Sriram Srivatsa; Colby R. Maldini; Jingxin Wang; Chungdhak Jaming Tsang; Ola Mohamed; Josephine Romano; Beth Haggarty; Gabriela Plesa; Avery L. Gaymon; Andrea L. Brennan; Elizabeth Veloso; Bruce L. Levine; Mary E. Putt; Irina Kulikovskaya
CCR5-targeted allogeneic gamma–delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy

CCR5靶向的异基因γ-δ CD19嵌合抗原受体T细胞用于HIV相关B细胞恶性免疫治疗

Nature Biomedical Engineering
IF26.6
2025-10-210
PRE
Ángel Ramírez-Fernández; Alexander J. Dimitri; Fang Chen; Robert Bartoszek; Gregory M. Chen; Laura Córdoba-Espejo; Yuqi Zhou; Yun-hsin Tang; Chien-Ting Lin; Reyes Acosta; John Scholler; Guido Ghilardi; Patrizia Porazzi; Mireia Pellicer; Núria Profitós-Pelejà; Stefan K. Barta; Anne Chew; Julie K. Jadlowsky; Vanessa E. Gonzalez; Donald L. Siegel; Bruce L. Levine; Gaël Roué; Marco Ruella; Michael T. Lotze; Carl H. June; James L. Riley; Joseph A. Fraietta
Clinical and molecular dissection of CAR T cell resistance in pancreatic cancer

胰腺癌中CAR T细胞耐药性的临床与分子解析

Cell Reports Medicine
IF10.6
2025-08-180
OAAI
M. Angela Aznar; Charly R. Good; Julie S. Barber-Rotenberg; Sangya Agarwal; Wesley Wilson; Alex Watts; Zhen Zhang; Donna Gonzales; Greg Donahue; Wei-Ting Hwang; Austin K. Rennels; Andrew J. Rech; Shunichiro Kuramitsu; Hua Huang; Karl M. Glastad; Katherine A. Alexander; Gabriela Plesa; Emily Dowd; Andrea Brennan; Donald L. Siegel; Janos Tanyi; Andrew Haas; Drew A. Torigian; Gregory Nadolski; Vanessa E. Gonzalez; Elizabeth O. Hexner; Joseph A. Fraietta; Julie K. Jadlowsky; Regina M. Young; Shelley L. Berger; Carl H. June; Mark H. O’Hara
Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial

Bagley SJ, Desai AS, Fraietta JA, Silverbush D, Chafamo D, Freeburg NF, et al. 静脉内双价CAR T细胞靶向EGFR和IL-13Rα2治疗复发性胶质母细胞瘤：一项1期临床试验。Nat Med. (2025). doi: 10.1038/s41591-025-03745-0

Nature Medicine
IF50
2025-06-010
PRE
Stephen J. Bagley; Arati S. Desai; Joseph A. Fraietta; Dana Silverbush; Daniel Chafamo; Nelson F. Freeburg; Gayathri Konanur Gopikrishna; Andrew J. Rech; Ali Nabavizadeh; Linda J. Bagley; Jungmin Park; Danuta Jarocha; Rene Martins; Nicolas Sarmiento; Eileen Maloney; Lester Lledo; Carly Stein; Amy Marshall; Rachel M. Leskowitz; Julie K. Jadlowsky; Shane Mackey; Shannon Christensen; Bike Su Oner; Gabriela Plesa; Andrea Brennan; Vanessa Gonzalez; Fang Chen; David Barrett; Robert Colbourn; MacLean P. Nasrallah; Zissimos Mourelatos; Wei-Ting Hwang; Cecile Alanio; Donald L. Siegel; Carl H. June; Elizabeth O. Hexner; Zev A. Binder; Donald M. O’Rourke
TET2 regulates early and late transitions in exhausted CD8+ T cell differentiation and limits CAR T cell function
SCIENCE ADVANCES
IF12.5
2024-11-150
OAAI
Dimitri, Alexander J.; Baxter, Amy E.; Chen, Gregory M.; Hopkins, Caitlin R.; Rouin, Geoffrey T.; Huang, Hua; Kong, Weimin; Holliday, Christopher H.; Wiebking, Volker; Bartoszek, Robert; Drury, Sydney; Dalton, Katherine; Koucky, Owen M.; Chen, Zeyu; Giles, Josephine R.; Dils, Alexander T.; Jung, In-Young; O'Connor, Roddy; Collins, Sierra; Everett, John K.; Amses, Kevin; Sherrill-Mix, Scott; Chandra, Aditi; Goldman, Naomi; Vahedi, Golnaz; Jadlowsky, Julie K.; Young, Regina M.; Melenhorst, Jan Joseph; Maude, Shannon L.; Levine, Bruce L.; Frey, Noelle V.; Berger, Shelley L.; Grupp, Stephan A.; Porter, David L.; Herbst, Friederike; Porteus, Matthew H.; Carty, Shannon A.; Bushman, Frederic D.; Weber, Evan W.; Wherry, E. John; Jordan, Martha S.; Fraietta, Joseph A.
Accelerating the development of genetically engineered cellular therapies: a framework for extrapolating data across related products
CYTOTHERAPY
IF3.2
2024-07-010
OAAI
Stewart, Mark D.; Kalos, Michael; Coutinho, Vicki; Better, Marc; Jazayeri, Jonathan; Yohrling, Jennifer; Jadlowsky, Julie; Fuchs, Miriam; Gidwani, Shalini; Goessl, Carsten; Hanley, Patrick J.; Healy, Jane; Liu, Wen; Mckelvey, Brittany A.; Pearce, Laura; Pilon-Thomas, Shari; Andrews, Hillary S.; Veldman, Monica; Vong, Judy; Weinbach, Susan P.; Allen, Jeff D.
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication (vol 131, e144486, 2021)
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-05-011
OAAI
Tebas, Pablo; Jadlowsky, Julie K.; Shaw, Pamela A.; Tian, Lifeng; Esparza, Erin; Brennan, Andrea L.; Kim, Sukyung; Naing, Soe Yu; Richardson, Max W.; Vogel, Ashley N.; Maldini, Colby R.; Kong, Hong; Liu, Xiaojun; Lacey, Simon F.; Bauer, Anya M.; Mampe, Felicity; Richman, Lee P.; Lee, Gary; Ando, Dale; Levine, Bruce L.; Porter, David L.; Zhao, Yangbing; Siegel, Don L.; Bar, Katharine J.; June, Carl H.; Riley, James L.
Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results

鞘内注射靶向EGFR和IL13Rα2的二价CAR T细胞治疗复发性胶质母细胞瘤: 1期试验中期结果

NATURE MEDICINE
IF50
2024-03-1364
PRE
Bagley, Stephen J.; Logun, Meghan; Fraietta, Joseph A.; Wang, Xin; Desai, Arati S.; Bagley, Linda J.; Nabavizadeh, Ali; Jarocha, Danuta; Martins, Rene; Maloney, Eileen; Lledo, Lester; Stein, Carly; Marshall, Amy; Leskowitz, Rachel; Jadlowsky, Julie K.; Christensen, Shannon; Oner, Bike Su; Plesa, Gabriela; Brennan, Andrea; Gonzalez, Vanessa; Chen, Fang; Sun, Yusha; Gladney, Whitney; Barrett, David; Nasrallah, MacLean P.; Hwang, Wei-Ting; Ming, Guo-Li; Song, Hongjun; Siegel, Donald L.; June, Carl H.; Hexner, Elizabeth O.; Binder, Zev A.; O'Rourke, Donald M.
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells

高活性间皮素定向CAR T细胞致严重肺毒性2例

MOLECULAR THERAPY
IF12
2023-08-0125
PRE
Haas, Andrew R.; Golden, Ryan J.; Litzky, Leslie A.; Engels, Boris; Zhao, Linlin; Xu, Fangmin; Taraszka, John A.; Ramones, Melissa; Granda, Brian; Chang, Wan-Jung; Jadlowsky, Julie; Shea, Kim-Marie; Runkle, Adam; Chew, Anne; Dowd, Emily; Gonzalez, Vanessa; Chen, Fang; Liu, Xiaojun; Fang, Chongyun; Jiang, Shuguang; Davis, Megan M.; Sheppard, Neil C.; Zhao, Yangbing; Fraietta, Joseph A.; Lacey, Simon F.; Plesa, Gabriela; Melenhorst, J. Joseph; Mansfield, Keith; Brogdon, Jennifer L.; Young, Regina M.; Albelda, Steven M.; June, Carl H.; Tanyi, Janos L.
BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-11-0957
OAAI
Jung, In-Young; Narayan, Vivek; McDonald, Sierra; Rech, Andrew J.; Bartoszek, Robert; Hong, Gwanui; Davis, Megan M.; Xu, Jun; Boesteanu, Alina C.; Barber-Rotenberg, Julie S.; Plesa, Gabriela; Lacey, Simon F.; Jadlowsky, Julie K.; Siegel, Donald L.; Hammill, Dana M.; Cho-Park, Park F.; Berger, Shelley L.; Haas, Naomi B.; Fraietta, Joseph A.
BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-08-1658
OA
Kong, Weimin; Dimitri, Alexander; Wang, Wenliang; Jung, In-Young; Ott, Christopher J.; Fasolino, Maria; Wang, Yan; Kulikovskaya, Irina; Gupta, Minnal; Yoder, Todd; DeNizio, Jamie E.; Everett, John K.; Williams, Erik F.; Xu, Jun; Scholler, John; Reich, Tyler J.; Bhoj, Vijay G.; Haines, Kathleen M.; Maus, Marcela, V; Melenhorst, J. Joseph; Young, Regina M.; Jadlowsky, Julie K.; Marcucci, Katherine T.; Bradner, James E.; Levine, Bruce L.; Porter, David L.; Bushman, Frederic D.; Kohli, Rahul M.; June, Carl H.; Davis, Megan M.; Lacey, Simon F.; Vahedi, Golnaz; Fraietta, Joseph A.
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-04-0160
OA
Tebas, Pablo; Jadlowsky, Julie K.; Shaw, Pamela A.; Tian, Lifeng; Esparza, Erin; Brennan, Andrea L.; Kim, Sukyung; Naing, Soe Yu; Richardson, Max W.; Vogel, Ashley N.; Maldini, Colby R.; Kong, Hong; Liu, Xiaojun; Lacey, Simon F.; Bauer, Anya M.; Mampe, Felicity; Richman, Lee P.; Lee, Gary; Ando, Dale; Levine, Bruce L.; Porter, David L.; Zhao, Yangbing; Siegel, Don L.; Bar, Katharine J.; June, Carl H.; Riley, James L.

研究方向

暂未获取到该数据
J
Joseph A. Fraietta
H 指数:45论文数:359被引数:1.5万
C
Carl H. June
H 指数:177论文数:1,428被引数:14.4万
G
Gabriela Plesa
H 指数:40论文数:245被引数:1.3万
B
Bruce L. Levine
H 指数:102论文数:550被引数:6.6万
V
Vanessa Gonzalez
H 指数:24论文数:138被引数:1.2万
D
Don L. Siegel
H 指数:42论文数:205被引数:6,672
S
Simon F. Lacey
H 指数:75论文数:382被引数:3.8万
A
Anne Chew
H 指数:28论文数:113被引数:1.7万
A
Alexander J. Dimitri
H 指数:7论文数:12被引数:662
J
James L. Riley
H 指数:76论文数:278被引数:2.6万