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T

Thomas G. Moens

Leuven Brain Institute
H指数:11
被引数:2,003

个人简介

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教育背景

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工作经历

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荣誉奖项

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Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo

双靶向CRISPR-CasRx在体外和体内均可降低C9orf72 ALS/FTD正义和反义重复RNA水平。

NATURE COMMUNICATIONS
IF15.7
2025-01-081
OA
Kempthorne, Liam; Vaizoglu, Deniz; Cammack, Alexander J.; Carcole, Mireia; Roberts, Martha J.; Mikheenko, Alla; Fisher, Alessia; Suklai, Pacharaporn; Muralidharan, Bhavana; Kroll, Francois; Moens, Thomas G.; Yshii, Lidia; Verschoren, Stijn; Holbling, Benedikt V.; Moreira, Francisco C.; Katona, Eszter; Coneys, Rachel; de Oliveira, Paula; Zhang, Yong-Jie; Jansen, Karen; Daughrity, Lillian M.; Mcgown, Alexander; Ramesh, Tennore M.; van den Bosch, Ludo; Lignani, Gabriele; Rahim, Ahad A.; Coyne, Alyssa N.; Petrucelli, Leonard; Rihel, Jason
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis

使用APEX进行应力颗粒分解的时空蛋白质组学分析揭示了sumo化的调节作用以及与ALS发病机理的联系

MOLECULAR CELL
IF16.6
2020-12-01147
OAAI
Marmor-Kollet, Hagai; Siany, Aviad; Kedersha, Nancy; Knafo, Naama; Rivkin, Natalia; Danino, Yehuda M.; Moens, Thomas G.; Olender, Tsviya; Sheban, Daoud; Cohen, Nir; Dadosh, Tali; Addadi, Yoseph; Ravid, Revital; Eitan, Chen; Cohen, Beata Toth; Hofmann, Sarah; Riggs, Claire L.; Advani, Vivek M.; Higginbottom, Adrian; Cooper-Knock, Johnathan; Hanna, Jacob H.; Merbl, Yifat; Van den Bosch, Ludo; Anderson, Paul; Ivanov, Pavel; Geiger, Tamar; Hornstein, Eran
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A
ACTA NEUROPATHOLOGICA
IF9.3
2019-01-0284
OAAI
Moens, Thomas G.; Niccoli, Teresa; Wilson, Katherine M.; Atilano, Magda L.; Birsa, Nicol; Gittings, Lauren M.; Holbling, Benedikt V.; Dyson, Miranda C.; Thoeng, Annora; Neeves, Jacob; Glaria, Idoia; Yu, Lu; Bussmann, Julia; Storkebaum, Erik; Pardo, Mercedes; Choudhary, Jyoti S.; Fratta, Pietro; Partridge, Linda; Isaacs, Adrian M.
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
EMBO MOLECULAR MEDICINE
IF8.3
2017-11-07180
OAAI
Simone, Roberto; Balendra, Rubika; Moens, Thomas G.; Preza, Elisavet; Wilson, Katherine M.; Heslegrave, Amanda; Woodling, Nathan S.; Niccoli, Teresa; Gilbert-Jaramillo, Javier; Abdelkarim, Samir; Clayton, Emma L.; Clarke, Mica; Konrad, Marie-Therese; Nicoll, Andrew J.; Mitchell, Jamie S.; Calvo, Andrea; Chio, Adriano; Houlden, Henry; Polke, James M.; Ismail, Mohamed A.; Stephens, Chad E.; Vo, Tam; Farahat, Abdelbasset A.; Wilson, W. David; Boykin, David W.; Zetterberg, Henrik; Partridge, Linda; Wray, Selina; Parkinson, Gary; Neidle, Stephen; Patani, Rickie; Fratta, Pietro; Isaacs, Adrian M.
A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology

淀粉样蛋白或Tau蛋白病理发展过程中转基因小鼠的全基因组基因表达分析和数据库

CELL REPORTS
IF6.9
2015-02-01218
OAAI
Matarin, Mar; Salih, Dervis A.; Yasvoina, Marina; Cummings, Damian M.; Guelfi, Sebastian; Liu, Wenfei; Solim, Muzammil A. Nahaboo; Moens, Thomas G.; Paublete, Rocio Moreno; Ali, Shabinah S.; Perona, Marina; Desai, Roshni; Smith, Kenneth J.; Latcham, Judy; Fulleylove, Michael; Richardson, Jill C.; Hardy, John; Edwards, Frances A.

研究方向

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L
Ludo Van Den Bosch
H 指数:82论文数:416被引数:3.3万
L
Linda Partridge
H 指数:134论文数:861被引数:9.1万
T
Teresa Niccoli
H 指数:18论文数:38被引数:3,920
A
Adrian M. Isaacs
H 指数:52论文数:231被引数:1.4万
H
Henrik Zetterberg
H 指数:190论文数:3,750被引数:17.9万
P
Philip Van Damme
H 指数:87论文数:546被引数:2.9万
A
Amanda Heslegrave
H 指数:55论文数:293被引数:8,538
R
Rubika Balendra
H 指数:13论文数:32被引数:1,598
A
Annora Thoeng
H 指数:16论文数:29被引数:2,412
K
Katarina Stoklund Dittlau
H 指数:9论文数:23被引数:479