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A

Amanda Heslegrave

Great Ormond Street Hospital for Children NHS Foundation Trust

55H指数
293论文数
8.5K被引数
收录论文 143
发表时间
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Defining the underlying pathology of corticobasal syndrome using clinical features and biomarkers利用临床特征和生物标志物界定皮质基底综合征的潜在病理机制
errBrain
IF11.7
err2026-08-06
err0
errOAAI
errDavid P Vaughan; Marte Theilmann Jensen; Raquel Real; Riona G Fumi; Lesley Wu; Danielle Lux; Megan Hodgson; P Simon Jones; Negin Holland; William J Scotton; Oiher Serrano-Assensio; Andrea Quattrone; Amanda J Heslegrave; Elena Veleva; Owen Swann; Henrik Zetterberg; Tim Lynch; Pablo Mir; Maria Stamelou; Klaus Seppi; Rik Vandenberghe; Thomas T Warner; Andrew Lees; Kailash P Bhatia; Alistair Church; Christopher Kobylecki; P Nigel Leigh; Michele T Hu; Pille Taba; Terje Matsalu; Nicola Pavese; Boyd C P Ghosh; Marina Picillo; Johan Wallin; Per Svenningson; Almudena Sánchez-Gómez; Manel Fernández; Ana Cámara; Lluís Planellas; Yaroslau Compta; PROSPECT consortium, MD-GAP; Annelies Quaegebeur; Zane Jaunmuktane; Tamas Revesz; Edwin Jabbari; Jonathan D Rohrer; James B Rowe; Huw R Morris
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Aging-related matrix metallopeptidase 10 and osteopontin levels are associated with pathology, cognitive decline, and age at onset in Alzheimer's disease与年龄相关的基质金属蛋白酶10和骨桥蛋白水平与阿尔茨海默病中的病理学、认知下降及发病年龄相关
erralzheimer's & dementia
IF0
err2026-04-22
err0
errOAAI
errBryan Ng; Eleftheria Kodosaki; Elena Veleva; Ashvini Keshavan; Jonathan M. Schott; Amanda J. Heslegrave; Nick C. Fox; Henrik Zetterberg
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Safety, efficacy, and distal nerve Schwann cell biodistribution in mice and NHPs to support translation of AAV9 RNAi therapy for CMT1A安全性、疗效及远端神经施万细胞在小鼠和非人灵长类动物中的生物分布，以支持AAV9 RNAi疗法在CMT1A中的转化应用
errMolecular Therapy Nucleic Acids
IF6.1
err2026-02-27
err0
errOAAI
errMarina Stavrou; Lindsay M. Wallace; Merlin Thangaraj; Noah K. Taylor; Alexia Kagiava; Revekka Papacharalambous; Cynthia McAllister; Gloria Zender; Nizar Y. Saad; M. Bilal Bayazit; Amanda Heslegrave; Christina Tryfonos; Jan Richter; Henrik Zetterberg; Brian Price; Rachel Salzman; Kleopas A. Kleopa; Scott Q. Harper
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Pilot Study of Fingolimod Treatment in Neuronal Ceroid Lipofuscinosis Type 1苯丁酸甘油酯治疗神经元蜡样脂褐质沉积症1型的初步研究
errNeurology-Genetics
IF3.7
err2026-02-01
err0
PREAI
errMessina, Martina; Whiteley, Rebecca; Gan, Chin; Heywood, Wendy E.; Heslegrave, Amanda J.; Keating, Megan; Taylor, Sophie; Footitt, Emma; Mills, Philippa; Hemingway, Cheryl; Gissen, Paul; Vecchiato, Katy
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Impact of meningoencephalitis and sepsis on delirium and subsequent neurological impairment in pediatric patients: a prospective proof-of-concept biomarker and EEG study脑膜脑炎和败血症对儿科患者谵妄及随后神经功能缺损的影响：一项前瞻性概念验证生物标志物和脑电图研究
errScientific Reports
IF3.9
err2025-12-08
err0
errOAAI
errFelix Klawitter; Johanna Hackenberg; Lena Danckert; Astrid Bertsche; Axel Petzold; Heidi A.B. Smith; Eugene Wesley Ely; Christian Spang; Rika Bajorat; Dagmar-Christiane Fischer; Gerd Klinkmann; Anne Körmann-Günther; Robert Fleischmann; Amanda Heslegrave; Henrik Zetterberg; Hessel Peters-Sengers; Johannes Ehler; Critical Care Consultant
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Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease脑脊液前强啡肽预测亨廷顿病临床运动诊断前数十年纹状体萎缩
errMovement Disorders
IF7.6
err2025-09-26
err0
errOAAI
errMena Farag MBBS, MRCP; Michael J. Murphy MB BCh BAO, MRCPI; Nicola Z. Hobbs PhD; Michela Leocadi PhD; Kate Fayer MRes; Olivia Thackeray MSc; Johan Gobom PhD; Marc Ciosi PhD; Amanda Heslegrave PhD; Henrik Zetterberg PhD; Douglas R. Langbehn MD, PhD; Darren G. Monckton PhD; Edward J. Wild MB BChir, FRCP, PhD; Sarah J. Tabrizi MBChB, FRCP, PhD, FMedSci; Rachael I. Scahill PhD
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Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's DiseaseGlymphatic Clearance受损，通过沿血管周围空间使用扩散张量图像分析（DTI-ALPS）进行测量，与帕金森病的不良认知结局相关联。
errMovement Disorders
IF7.6
err2025-08-07
err0
errOAAI
errAngeliki Zarkali PhD; George Thomas PhD; Ross Paterson PhD, MBBS; Naomi Hannaway MSc; Ivelina Dobreva MSc; Amanda J. Heslegrave PhD; Elena Veleva PhD; Henrik Zetterberg PhD; Rimona S. Weil PhD
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Reply: Reconsidering white matter vulnerability and biomarker interpretation across Lewy body dementia subtypes回复：重新审视白质脆弱性和生物标志物解释在路易体痴呆亚型中的差异
errAlzheimer's & Dementia
IF11.1
err2025-08-07
err0
errOAAI
errNaomi Hannaway; Angeliki Zarkali; Rohan Bhome; Ivelina Dobreva; George EC Thomas; Elena Veleva; Irene Gorostiaga Belio; Katie Tucker; Amanda Heslegrave; Henrik Zetterberg; Rimona S Weil
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Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy每周一次艾塞那肽在多系统萎缩患者治疗中的应用
errAnnals of Neurology
IF7.7
err2025-07-29
err0
errOAAI
errNirosen Vijiaratnam PhD; Christine Girges PhD; Martin Wiegand PhD; Claudia Ismail BSc; Alexandra Lameirinhas BSc; Alison Yarnall PhD; Cameron Kirk PhD; Silvia Del-Din PhD; Lynn Rochester PhD; Christopher Kobylecki PhD; Gareth Ambler PhD; Simon Skene PhD; Henry Houlden PhD; Viorica Chelban PhD; Amanda Heslegrave PhD; Wendy Phillips PhD; Alan Whone PhD; Niall Quinn PhD; Christian Lambert PhD; Charlotte Dore MSc; Huw R. Morris PhD; Mathew H. Horrocks PhD; Ji Eun Lee PhD; Judi O'Shaughnessy; Yazhou Li PhD; Nigel H. Greig PhD; Sonia Gandhi PhD; Vincenzo Libri MD; Dilan Athauda PhD; Tom Foltynie PhD
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Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases评估指血采集在神经疾病中神经丝蛋白轻链远程定量中的应用
errJournal of Neurology
IF4.6
err2025-07-10
err0
errOAAI
errAnnabelle Coleman; Alexiane Touzé; Mena Farag; Marta Pengo; Michael J. Murphy; Yara Hassan; Olivia Thackeray; Kate Fayer; Sophie Field; Mitsuko Nakajima; Elizabeth L. Broom; Nicola Z. Hobbs; Brook Huxford; Natalie Donkor; Ellen Camboe; Kamalesh C. Dey; Alexandra Zirra; Aisha Ahmed; Ana Rita Gameiro Costa; Harriet Sorrell; Luca Zampedri; Vittoria Lombardi; Charles Wade; Sean Mangion; Batoul Fneich; Amanda Heslegrave; Henrik Zetterberg; Rachael Scahill; Alastair Noyce; Andrea Malaspina; Jeremy Chataway; Sarah J. Tabrizi; Lauren M. Byrne
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Progression of biological markers in spinocerebellar ataxia type 3: longitudinal analysis of prospective data from the ESMI cohort脊髓小脑共济失调3型的生物标志物进展：ESMI队列前瞻性数据的纵向分析
errlancet regional health europe
IF0
err2025-07-03
err0
PREAI
errMoritz Berger; Hector Garcia-Moreno; Mónica Ferreira; Jeannette Hubener-Schmid; Tamara Schaprian; Philipp Wegner; Tim Elter; Kennet M. Teichmann; Magda M. Santana; Marcus Grobe-Einsler; Demet Oender; Berkan S.C. Koyak; Sarah Bernsen; Luís Pereira de Almeida; Patrick Silva; Joana Afonso Ribeiro; Inês Cunha; Cristina Gonzalez-Robles; Shamsher Khan; Amanda Heslegrave; Jennifer Faber
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Biomarker evidence of neurodegeneration in mid-life former rugby players中年前橄榄球运动员神经退行性变的生物标志物证据
errBRAIN
IF11.7
err2025-07-01
err2
errOAAI
errGraham, Neil S. N.; Zimmerman, Karl A.; Hain, Jessica; Rooney, Erin; Lee, Ying; Del Giovane, Martina; Parker, Thomas; Wilson, Mathew G.; Malhotra, Paresh; David, Michael C. B.; Kolanko, Magdalena; Patel, Maneesh; Veleva, Elena; Swann, Owen; Heslegrave, Amanda; Zetterberg, Henrik; Friedland, Daniel; Sylvester, Richard; Sharp, David J.
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Current Methods in Clinical Alzheimer’s Disease Research and Diagnosis阿尔茨海默病临床研究及诊断的当前方法
errMolecular Diagnosis & Therapy
IF4.4
err2025-06-07
err0
PREAI
errEleftheria Kodosaki; Henrik Zetterberg; Amanda Heslegrave
err分享
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Novel blood-based proteomic signatures across multiple neurodegenerative diseases多种神经退行性疾病的新型血液蛋白质组学标志物
errALZHEIMERS & DEMENTIA
IF11.1
err2025-03-27
err0
errOAAI
errDurcan, Robert; Heslegrave, Amanda; Swann, Peter; Goddard, Julia; Chouliaras, Leonidas; Murley, Alexander G.; Savulich, George; Bevan-Jones, W. Richard; Swann, Owen; Ashton, Nicholas J.; Blennow, Kaj; Mcewan, William; Zetterberg, Henrik; Rowe, James B.; O'Brien, John T.; Malpetti, Maura
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Niacin ameliorates Charcot-Marie-Tooth 4B1 neuropathy without interfering with nerve regeneration
errBRAIN COMMUNICATIONS
IF4.5
err2025-01-31
err0
errOAAI
errCipriani, Silvia; Porrello, Emanuela; Cerea, Matteo; Gazzaniga, Andrea; Di Guardo, Roberta; Heslegrave, Amanda; Valenzano, Serena; Del Carro, Ubaldo; Duong, Phu; Svaren, John; Previtali, Stefano Carlo; Bolino, Alessandra
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Polygenic risk discriminates Lewy body dementia from Alzheimer's disease多基因风险可区分路易体痴呆与阿尔茨海默病
errALZHEIMERS & DEMENTIA
IF11.1
err2025-01-24
err0
errOAAI
errMckeever, A; Swann, P; Malpetti, M; Donaghy, PC; Thomas, A; Mak, E; Carter, SF; Tan, JHK; Hong, YT; Fryer, TD; Heslegrave, A; Zetterberg, H; Su, L; Chouliaras, L; Rowe, JB; O'Brien, JT
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Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy炎症PET和血浆神经丝蛋白轻链预测进行性核上性麻痹患者的生存情况
errBRAIN COMMUNICATIONS
IF4.5
err2025-01-01
err0
errOAAI
errShapiro, Noah L.; Jones, Peter Simon; Mak, Elijah; Tsvetanov, Kamen A.; Goddard, Julia; Vontobel, Davi S.; Durcan, Robert; Chouliaras, Leonidas; Fryer, Tim; Hong, Young T.; Aigbirhio, Franklin; Heslegrave, Amanda; Franzmeier, Nicolai; Brendel, Matthias; Zetterberg, Henrik; O'Brien, John T.; Rowe, James B.; Malpetti, Maura
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How well do plasma Alzheimer's disease biomarkers reflect the CSF amyloid status?
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2024-12-18
err0
PREAI
errHazan, Jemma; Abel, Emily; Grilo, Miguel Rosa; Alawode, Deborah; Laranjinha, Ines; Heslegrave, Amanda J.; Liu, Kathy Y.; Schott, Jonathan M.; Howard, Robert; Zetterberg, Henrik; Fox, Nick C.
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More than microglia: myeloid cells and biomarkers in neurodegeneration不仅仅是小胶质细胞: 髓样细胞和神经变性中的生物标志物
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2024-10-31
err0
errOAAI
errKodosaki, Eleftheria; Bell, Rosie; Sogorb-Esteve, Aitana; Wiltshire, Katharine; Zetterberg, Henrik; Heslegrave, Amanda
err分享
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Neurodegenerative fluid biomarkers are enriched in human cervical lymph nodes神经变性液体生物标志物在人颈部淋巴结中富集
errBRAIN
IF11.7
err2024-10-21
err1
errOAAI
errAl-Diwani, Adam; Provine, Nicholas M.; Murchison, Andrew; Laban, Rhiannon; Swann, Owen J.; Koychev, Ivan; Sheerin, Fintan; Da Mesquita, Sandro; Heslegrave, Amanda; Zetterberg, Henrik; Klenerman, Paul; Irani, Sarosh R.
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