logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
K

Keimpe Wierda

vib-ku leuven center for brain & disease research

29H指数
68论文数
3.8K被引数
收录论文 35
发表时间
logo
ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesisATP13A4调控细胞外多胺水平以控制兴奋性突触发生
errNature Communications
IF15.7
err2026-08-04
err0
errOAAI
errSarah van Veen; Emily Meeus; Dolores Irala; Kristina Sakers; Zhaolin Liu; Justin Savage; Gabrielle Séjourné; Dhanesh Sivadasan Bindu; Elke Ausloos; Hanna Elzbieta Grzesik; Hanne Dhondt; Nina Schoonvliet; Chris Van den Haute; Joris Van Asselberghs; Marta Montpeyó Garcia-Moreno; Keimpe Wierda; Veerle Baekelandt; Konrad Platzer; Kevin Rostasy; Kai Lee Yap; Jan Eggermont; Matthew G. Holt; Cagla Eroglu; Peter Vangheluwe
err分享
err收藏
Developing mouse inhibitory neuron single-cell transcriptomes reveal distinct modes of cell-type diversification发育中小鼠抑制性神经元单细胞转录组揭示细胞类型多样化的不同模式
errNature Neuroscience
IF20
err2026-08-03
err0
errOAAI
errMinhui Liu; Facundo Ferrero Restelli; Elia Micoli; Giulia Barbiera; Rani Moors; Evelien Nouboers; Malou Reverendo; Jessica Xinyun Du; Hannah Bertels; Dimitris Konstantopoulos; Keimpe Wierda; Aya Takeoka; Giordano Lippi; Lynette Lim
err分享
err收藏
Phenotypic diversity is caused by non-linear genetic interactions between two SNAREopathy genes表型多样性是由两种SNAREopathy基因之间的非线性遗传相互作用引起的。
errMolecular Psychiatry
IF10.1
err2026-03-05
err0
errOAAI
errJovana Kovačević; Sébastien Houy; Johny Pires; Anna Kádková; Zhen Li; Hanna C. A. Lammertse; Joana S. Martins; Miriam Öttl; Keimpe Wierda; Joke Wortel; Jakob B. Sørensen; Matthijs Verhage
err分享
err收藏
A dynamic gene regulatory code drives synaptic development of hippocampal granule cells一个动态的基因调控密码驱动海马颗粒细胞的突触发育
errScience Advances
IF12.5
err2025-10-22
err0
PREAI
errBlanca Lorente-Echeverría; Danie Daaboul; Jeroen Vandensteen; Gabriele Marcassa; Willem Naert; Joris Vandenbempt; Elke Leysen; Malou Reverendo; Ine Vlaeminck; Lise Vervloessem; Jochen Lamote; Suresh Poovathingal; Kristofer Davie; Keimpe Wierda; Dan Dascenco; Stein Aerts; Joris de Wit
err分享
err收藏
The neural basis of species-specific defensive behaviour in Peromyscus micePeromyscus小鼠物种特异性防御行为的神经基础
errNature
IF48.5
err2025-07-23
err0
errOAAI
errFelix Baier; Katja Reinhard; Bram Nuttin; Arnau Sans-Dublanc; Chen Liu; Victoria Tong; Julie S. Murmann; Keimpe Wierda; Karl Farrow; Hopi E. Hoekstra
err分享
err收藏
A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation一个突触后GPR158-PLCXD2复合物调控棘状装置的丰度和树突棘成熟
errDevelopmental Cell
IF8.7
err2025-05-19
err0
PREAI
errBen Verpoort; Luísa Amado; Jeroen Vandensteen; Elke Leysen; Dan Dascenco; Joris Vandenbempt; Irma Lemmens; Joris Wauman; Kristel Vennekens; Abril Escamilla-Ayala; Ana Cristina Nogueira Freitas; Thomas Voets; Sebastian Munck; Jan Tavernier; Keimpe Wierda; Joris de Wit
err分享
err收藏
Altered expression of Presenilin2 impacts endolysosomal homeostasis and synapse function in Alzheimer's disease-relevant brain circuitsPresenilin2的表达改变会影响阿尔茨海默氏病相关脑回路中的溶酶体内稳态和突触功能
errNATURE COMMUNICATIONS
IF15.7
err2024-11-29
err0
errOAAI
errPerdok, Anika; Van Acker, Zoe P.; Vrancx, Celine; Sannerud, Ragna; Vorsters, Inge; Verrengia, Assunta; Callaerts-Vegh, Zsuzsanna; Creemers, Eline; Fernandez, Sara Gutierrez; D'hauw, Britt; Serneels, Lutgarde; Wierda, Keimpe; Chavez-Gutierrez, Lucia; Annaert, Wim
err分享
err收藏
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells (vol 227, 116445, 2024)
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2024-11-01
err0
PREAI
errDe Vos, Kristof; Mavrogiannis, Adamantios; Wolters, Justina Clarinda; Schlenner, Susan; Calabuig, Alvaro Cortes; Wierda, Keimpe; Chinnaraj, Reena; Dermesrobian, Vera; Armoudjian, Yeghig; Jacquemyn, Maarten; Corthout, Nikky; Daelemans, Dirk; Annaert, Pieter
err分享
err收藏
Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition
errNEURON
IF15
err2024-11-01
err1
errOAAI
errLibe-Philippot, Baptiste; Iwata, Ryohei; Recupero, Aleksandra J.; Wierda, Keimpe; Garcia, Sergio Bernal; Hammond, Luke; van Benthem, Anja; Limame, Ridha; Ditkowska, Martyna; Beckers, Sofie; Gaspariunaite, Vaiva; Peze-Heidsieck, Eugenie; Remans, Daan; Charrier, Cecile; Theys, Tom; Polleux, Franck; Vanderhaeghen, Pierre
err分享
err收藏
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2024-09-01
err1
PREAI
errDe Vos, Kristof; Mavrogiannis, Adamantios; Wolters, Justina Clarinda; Schlenner, Susan; Wierda, Keimpe; Calabuig, Alvaro Cortes; Chinnaraj, Reena; Dermesrobian, Vera; Armoudjian, Yeghig; Jacquemyn, Maarten; Corthout, Nikky; Daelemans, Dirk; Annaert, Pieter
err分享
err收藏
SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo
errNEURON
IF15
err2024-09-01
err2
errOAAI
errVermaercke, Ben; Iwata, Ryohei; Wierda, Keimpe; Boubakar, Leila; Rodriguez, Paula; Ditkowska, Martyna; Bonin, Vincent; Vanderhaeghen, Pierre
err分享
err收藏
Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
errDEVELOPMENTAL CELL
IF8.7
err2024-06-01
err7
errOAAI
errBretou, Marine; Sannerud, Ragna; Escamilla-Ayala, Abril; Leroy, Tom; Vrancx, Celine; Van Acker, Zoe P.; Perdok, Anika; Vermeire, Wendy; Vorsters, Inge; Van Keymolen, Sophie; Maxson, Michelle; Pavie, Benjamin; Wierda, Keimpe; Eskelinen, Eeva-Liisa; Annaert, Wim
err分享
err收藏
An immunological puzzle: The adaptive immune system fuels Alzheimer's disease pathology
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2024-03-01
err1
errOAAI
errVan Hoecke, Lien; Castelein, Jonas; Xie, Junhua; Van Acker, Lore; Van Imschoot, Griet; Van Wonterghem, Elien; Vlaeminck, Ine; Verhaege, Daan; Claeys, Wouter; Wierda, Keimpe; Callaerts-Vegh, Zsuzsanna; Vandenbroucke, Roosmarijn E.
err分享
err收藏
Spatially Self-Organized Three-Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development空间自组织三维神经Concentroid作为一种新颖的还原论人源化模型来研究神经血管发育
errADVANCED SCIENCE
IF14.1
err2023-11-30
err2
errOAAI
errChai, Yoke Chin; To, San Kit; Simorgh, Susan; Zaunz, Samantha; Zhu, Yingli; Ahuja, Karan; Lemaitre, Alix; Ramezankhani, Roya; van der Veer, Bernard K.; Wierda, Keimpe; Verhulst, Stefaan; van Grunsven, Leo A.; Pasque, Vincent; Verfaillie, Catherine
err分享
err收藏
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling
errJOURNAL OF EXTRACELLULAR VESICLES
IF14.5
err2023-02-15
err57
errOAAI
errXie, Junhua; Cools, Lien; Van Imschoot, Griet; Van Wonterghem, Elien; Pauwels, Marie J.; Vlaeminck, Ine; De Witte, Chloe; EL Andaloussi, Samir; Wierda, Keimpe; De Groef, Lies; Haesebrouck, Freddy; Van Hoecke, Lien; Vandenbroucke, Roosmarijn E.
err分享
err收藏
A FACILE METHOD TO GENERATE CEREBRAL ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS一种从人多能干细胞产生脑类器官的简便方法
errEXCLI JOURNAL
IF4.9
err2023-01-01
err2
PREAI
errSimorgh, Susan; Mousavi, Seyed Ahmad; To, San Kit; Pasque, Vincent; Wierda, Keimpe; Vervliet, Tim; Yeganeh, Meghdad; Pooyan, Paria; Chai, Yoke Chin; Verfaillie, Catherine; Baharvand, Hossein
err分享
err收藏
KIF2A deficiency causes early-onset neurodegeneration
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-11-07
err9
errOAAI
errRuiz-Reig, Nuria; Chehade, Georges; Hakanen, Janne; Aittaleb, Mohamed; Wierda, Keimpe; De Wit, Joris; Nguyen, Laurent; Gailly, Philippe; Tissir, Fadel
err分享
err收藏
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagyDJ-1是PINK1/parkin依赖性线粒体自噬的重要下游介体
errBRAIN
IF11.7
err2022-08-30
err51
errOAAI
errImberechts, Dorien; Kinnart, Inge; Wauters, Fieke; Terbeek, Joanne; Manders, Liselot; Wierda, Keimpe; Eggermont, Kristel; Madeiro, Rodrigo Furtado; Sue, Carolyn; Verfaillie, Catherine; Vandenberghe, Wim
err分享
err收藏
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation白细胞介素2的星形胶质细胞靶向基因递送特异性增加脑驻留调节性T细胞数量并防止病理性神经炎症
errNATURE IMMUNOLOGY
IF27.6
err2022-05-26
err87
errOAAI
errYshii, Lidia; Pasciuto, Emanuela; Bielefeld, Pascal; Mascali, Loriana; Lemaitre, Pierre; Marino, Marika; Dooley, James; Kouser, Lubna; Verschoren, Stijn; Lagou, Vasiliki; Kemps, Hannelore; Gervois, Pascal; de Boer, Antina; Burton, Oliver T.; Wahis, Jerome; Verhaert, Jens; Tareen, Samar; Roca, Carlos P.; Singh, Kailash; Whyte, Carly E.; Kerstens, Axelle; Callaerts-Vegh, Zsuzsanna; Poovathingal, Suresh; Prezzemolo, Teresa; Wierda, Keimpe; Dashwood, Amy; Xie, Junhua; Van Wonterghem, Elien; Creemers, Eline; Aloulou, Meryem; Gsell, Willy; Abiega, Oihane; Munck, Sebastian; Vandenbroucke, Roosmarijn E.; Bronckaers, Annelies; Lemmens, Robin; De Strooper, Bart; Van Den Bosch, Ludo; Himmelreich, Uwe; Fitzsimons, Carlos P.; Holt, Matthew G.; Liston, Adrian
err分享
err收藏
AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease modelAAV介导的anti-BACE1 VHH递送减轻阿尔茨海默病模型的病理
errEMBO MOLECULAR MEDICINE
IF8.3
err2022-03-30
err23
errOAAI
errMarino, Marika; Zhou, Lujia; Rincon, Melvin Y.; Callaerts-Vegh, Zsuzsanna; Verhaert, Jens; Wahis, Jerome; Creemers, Eline; Yshii, Lidia; Wierda, Keimpe; Saito, Takashi; Marneffe, Catherine; Voytyuk, Iryna; Wouters, Yessica; Dewilde, Maarten; Duque, Sandra, I; Vincke, Cecile; Levites, Yona; Golde, Todd E.; Saido, Takaomi C.; Muyldermans, Serge; Liston, Adrian; De Strooper, Bart; Holt, Matthew G.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
J
John R. Yates
H 指数: 188 · 论文数: 1.5K
B
Bart De Strooper
H 指数: 142 · 论文数: 686
T
Takaomi C. Saido
H 指数: 112 · 论文数: 820
T
Todd E. Golde
H 指数: 110 · 论文数: 537
K
Kris Gevaert
H 指数: 103 · 论文数: 639
查看更多