未登录 Why choose between prediction power and mechanistic insight in QSRR modeling? A case study of artificial membrane chromatography and machine learning 为何在QSRR建模中需要在预测能力和机制洞察之间进行选择？——人工膜色谱与机器学习的案例研究 Nisterenko, Wiktor; Nicman, Julia; Deng, Jiayin; Singh, Yash Raj; Rozycka, Alicja; Greber, Katarzyna Ewa; Szulczyk, Daniel; Nowacki, Michal; Dawidowski, Maciej; Drabczyk, Anna; Jaskowska, Jolanta; Zareba, Przemyslaw; Kulaga, Damian; Staszewski, Marek; Wujec, Monika; Krzeczynski, Piotr; Michalak, Olga; Klejborowska, Greta; Scarpellini, Camilla; Augustyns, Koen; Dernovsek, Jaka; Tomasic, Tihomir; Korabecny, Jan; Fedorowicz, Joanna; Saczewski, Jaroslaw; Sawicki, Wieslaw; Ouyang, Defang; Ciura, Krzesimir 分享 收藏
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Using protease inhibitors to prevent intraperitoneal adhesions: effects of nafamostat mesylate, UAMC-00050, GM6001, and enoxaparin in the cecal ligation and puncture model and the ischemic button model 使用蛋白酶抑制剂预防腹腔粘连：纳法莫司特甲磺酸盐、UAMC-00050、GM6001和依诺肝素在盲肠结扎穿刺模型和缺血性钮扣模型中的效果 Plaeke, Philip; De Man, Joris; Hong, Gun-Soo; De Bruyn, Michelle; De Meester, Ingrid; Jorens, Philippe G.; Augustyns, Koen; Kalff, Joerg C.; Wehner, Sven; Hubens, Guy; De Winter, Benedicte 分享 收藏
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Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active 人源精液外泌体上的人源跨膜丝氨酸蛋白酶2 (TMPRSS2) 具有蛋白水解活性 Verhulst, Emile; De Bruyn, Michelle; Berckmans, Pascale; Sim, Yani; Augustyns, Koen; Pintelon, Isabel; Berg, Maya; Van Wielendaele, Pieter; Lambeir, Anne-Marie; Sterckx, Yann G. -J.; Nelissen, Inge; De Meester, Ingrid 分享 收藏
Intrinsic temperature increase drives lipid metabolism towards ferroptosis evasion and chemotherapy resistance in pancreatic cancer 内在性温度升高促使脂质代谢向铁死亡逃逸和胰腺癌化疗耐药方向发展 de Laat, Vincent; Topal, Halit; Spotbeen, Xander; Talebi, Ali; Dehairs, Jonas; Idkowiak, Jakub; Vanderhoydonc, Frank; Ostyn, Tessa; Zhao, Peihua; Jacquemyn, Maarten; Woelk, Michele; Sablina, Anna; Augustyns, Koen; Vanden Berghe, Tom; Roskams, Tania; Daelemans, Dirk; Fedorova, Maria; Topal, Baki; Swinnen, Johannes V. 分享 收藏
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease 铁死亡是代谢功能障碍相关的脂肪性肝病的靶向有害因素 Peleman, Cedric; Hellemans, Stig; Veeckmans, Geraldine; Arras, Wout; Zheng, Hao; Koeken, Ine; Van San, Emily; Hassannia, Behrouz; Walravens, Magali; Kayirangwa, Edissa; Beyene, Nateneal Tamerat; Van Herck, Mikhail Alfons; De Vos, Winnok Harald; Pintelon, Isabel; van Nassauw, Luc; Oosterlinck, Baptiste; Smet, Annemieke; Vits, Lieve; Dirinck, Eveline; Verrijken, An; De Man, Joris; Van Eyck, Annelies; Kwanten, Wilhelmus Josephus; Vonghia, Luisa; Driessen, Ann; Augustyns, Koen; Toyokuni, Shinya; De Winter, Benedicte; Van Steenkiste, Christophe; Francque, Sven; Vanden Berghe, Tom 分享 收藏
Druglike, 18F-labeled PET Tracers Targeting Fibroblast Activation Protein Tanc, Muhammet; Filippi, Nicolo; Van Rymenant, Yentl; Grintsevich, Sergei; Pintelon, Isabel; Verschuuren, Marlies; De Loose, Joni; Verhulst, Emile; Moon, Euy Sung; Cianni, Lorenzo; Stroobants, Sigrid; Augustyns, Koen; Roesch, Frank; De Meester, Ingrid; Elvas, Filipe; van der Veken, Pieter 分享 收藏
A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors Smiejkowska, Natalia; Oorts, Lauren; Van Calster, Kevin; De Vooght, Linda; Geens, Rob; Mattelaer, Henri-Philippe; Augustyns, Koen; Strelkov, Sergei V.; Lamprecht, Dirk; Temmerman, Koen; Sterckx, Yann G. -J.; Cappoen, Davie; Cos, Paul 分享 收藏
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Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin 来自临床使用的DPP4-Inhibitor维格列汀的二肽基肽酶9 (DPP9) 的高度选择性抑制剂 Benramdane, Siham; De Loose, Joni; Filippi, Nicolo; Espadinha, Margarida; Beyens, Olivier; Van Rymenant, Yentl; Dirkx, Laura; Bozdag, Murat; Feijens, Pim-Bart; Augustyns, Koen; Caljon, Guy; De Winter, Hans; De Meester, Ingrid; van der Veken, Pieter 分享 收藏
Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression Ferroptosis有助于多发性硬化及其药理学靶向抑制实验性疾病进展 Van San, Emily; Debruyne, Angela C. C.; Veeckmans, Geraldine; Tyurina, Yulia Y. Y.; Tyurin, Vladimir A. A.; Zheng, Hao; Choi, Sze Men; Augustyns, Koen; van Loo, Geert; Michalke, Bernhard; Venkataramani, Vivek; Toyokuni, Shinya; Bayir, Huelya; Vandenabeele, Peter; Hassannia, Behrouz; Vanden Berghe, Tom 分享 收藏
Effect of erythrophagocytosis-induced ferroptosis during angiogenesis in atherosclerotic plaques 红细胞吞噬作用诱导的铁吞噬作用在动脉粥样硬化斑块血管生成中的作用 Puylaert, Pauline; Roth, Lynn; Van Praet, Melissa; Pintelon, Isabel; Dumitrascu, Catalina; van Nuijs, Alexander; Klejborowska, Greta; Guns, Pieter-Jan; Berghe, Tom Vanden; Augustyns, Koen; De Meyer, Guido R. Y.; Martinet, Wim 分享 收藏
From PERK to RIPK1: Design, synthesis and evaluation of novel potent and selective necroptosis inhibitors 从PERK到RIPK1: 新型有效和选择性坏死性凋亡抑制剂的设计，合成和评估 Scarpellini, Camilla; Valembois, Sophie; Goossens, Kenneth; Vadi, Mike; Lanthier, Caroline; Klejborowska, Greta; Van der Veken, Pieter; De Winter, Hans; Bertrand, Mathieu J. M.; Augustyns, Koen 分享 收藏
Selected strategies to fight pathogenic bacteria Plotniece, Aiva; Sobolev, Arkadij; Supuran, Claudiu T.; Carta, Fabrizio; Bjoerkling, Fredrik; Franzyk, Henrik; Yli-Kauhaluoma, Jari; Augustyns, Koen; Cos, Paul; De Vooght, Linda; Govaerts, Matthias; Aizawa, Juliana; Tammela, Paeivi; Zalubovskis, Raivis 分享 收藏
Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases 化学多样的基于活性的探针，具有意想不到的抑制机制，靶向胰蛋白酶样丝氨酸蛋白酶 Ramos-Llorca, Alba; Decraecker, Lisse; Cacheux, Valerie M. Y.; Zeiburlina, Irena; De Bruyn, Michelle; Battut, Louise; Moreno-Cinos, Carlos; Ceradini, Davide; Espinosa, Eric; Dietrich, Gilles; Berg, Maya; De Meester, Ingrid; van der Veken, Pieter; Boeckxstaens, Guy; Lambeir, Anne-Marie; Denadai-Souza, Alexandre; Augustyns, Koen 分享 收藏
A Novel Ferroptosis Inhibitor UAMC-3203, a Potential Treatment for Corneal Epithelial Wound Balla, Anusha; Tran, Bao; Valtari, Annika; Steven, Philipp; Scarpellini, Camilla; Augustyns, Koen; Urtti, Arto; Vellonen, Kati-Sisko; Ruponen, Marika 分享 收藏
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