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Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active 人源精液外泌体上的人源跨膜丝氨酸蛋白酶2 (TMPRSS2) 具有蛋白水解活性 Verhulst, Emile; De Bruyn, Michelle; Berckmans, Pascale; Sim, Yani; Augustyns, Koen; Pintelon, Isabel; Berg, Maya; Van Wielendaele, Pieter; Lambeir, Anne-Marie; Sterckx, Yann G. -J.; Nelissen, Inge; De Meester, Ingrid 分享 收藏
The prolyl oligopeptidase and α-synuclein connection revisited 重新审视了脯氨酰寡肽酶和 α-突触核蛋白的连接 Van Elzen, Roos; Waumans, Yannick; Nath, Sangeeta; van der Veken, Pieter; Kerkhoff, Sonja; Van Dijk, Evert; Morawski, Markus; Ner, Steffen Ro, I; Engelborghs, Yves; De Meester, Ingrid; Lambeir, Anne-Marie 分享 收藏
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5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions Patsi, Henri T.; Kilpelainen, Tommi P.; Jumppanen, Mikael; Uhari-Vaananen, Johanna; Wielendaele, Pieter Van; De Lorenzo, Francesca; Cui, Hengjing; Auno, Samuli; Saharinen, Janne; Seppala, Erin; Sipari, Nina; Savinainen, Juha; De Meester, Ingrid; Lambeir, Anne-Marie; Lahtela-Kakkonen, Maija; Myohanen, Timo T.; Wallen, Erik A. A. 分享 收藏
Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases 化学多样的基于活性的探针，具有意想不到的抑制机制，靶向胰蛋白酶样丝氨酸蛋白酶 Ramos-Llorca, Alba; Decraecker, Lisse; Cacheux, Valerie M. Y.; Zeiburlina, Irena; De Bruyn, Michelle; Battut, Louise; Moreno-Cinos, Carlos; Ceradini, Davide; Espinosa, Eric; Dietrich, Gilles; Berg, Maya; De Meester, Ingrid; van der Veken, Pieter; Boeckxstaens, Guy; Lambeir, Anne-Marie; Denadai-Souza, Alexandre; Augustyns, Koen 分享 收藏
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In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes Van Rymenant, Yentl; Tanc, Muhammet; Van Elzen, Roos; Bracke, An; De Wever, Olivier; Augustyns, Koen; Lambeir, Anne-Marie; Kockx, Mark; De Meester, Ingrid; Van Der Veken, Pieter 分享 收藏
Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke 选择性抑制羧肽酶U可减少大鼠实验性中风的微血管血栓形成 Mertens, Joachim C.; Boisseau, William; Leenaerts, Dorien; Di Meglio, Lucas; Loyau, Stephane; Lambeir, Anne-Marie; Ducroux, Celina; Jandrot-Perrus, Martine; Michel, Jean-Baptiste; Mazighi, Mikael; Hendriks, Dirk; Desilles, Jean-Philippe 分享 收藏
A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation Joossen, Cedric; Baan, Adrienn; Moreno-Cinos, Carlos; Joossens, Jurgen; Cools, Nathalie; Lanckacker, Ellen; Moons, Lieve; Lemmens, Kim; Lambeir, Anne-Marie; Fransen, Erik; Delputte, Peter; Caljon, Guy; Van der Veken, Pieter; Maes, Louis; De Meester, Ingrid; Kiekens, Filip; Augustyns, Koen; Cos, Paul 分享 收藏
The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy Kilpelainen, Tommi P.; Hellinen, Laura; Vrijdag, Johannes; Yan, Xu; Svarcbahs, Reinis; Vellonen, Kati-Sisko; Lambeir, Anne-Marie; Huttunen, Henri; Urtti, Arto; Wallen, Erik A. A.; Myohanen, Timo T. 分享 收藏
Small molecule 3PO inhibits glycolysis but does not bind to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) Veseli, Besa Emini; Perrotta, Paola; Van Wielendaele, Pieter; Lambeir, Anne-Marie; Abdali, Anahita; Bellosta, Stefano; Monaco, Giovanni; Bultynck, Geert; Martinet, Wim; De Meyer, Guido R. Y. 分享 收藏
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Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP) 新型小分子衍生的高选择性成纤维细胞活化蛋白 (FAP) 底物 De Decker, An; Vliegen, Gwendolyn; Van Rompaey, Dries; Peeraer, Anke; Bracke, An; Verckist, Line; Jansen, Koen; Geiss-Friedlander, Ruth; Augustyns, Koen; De Winter, Hans; De Meester, Ingrid; Lambeir, Anne-Marie; Van der Veken, Pieter 分享 收藏
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DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages de Vasconcelos, Nathalia M.; Vliegen, Gwendolyn; Goncalves, Amanda; De Hert, Emilie; Martin-Perez, Rosa; Van Opdenbosch, Nina; Jallapally, Anvesh; Geiss-Friedlander, Ruth; Lambeir, Anne-Marie; Augustyns, Koen; Van Der Veken, Pieter; De Meester, Ingrid; Lamkanfi, Mohamed 分享 收藏
Carboxypeptidase U (CPU, carboxypeptidase B2, activated thrombin-activatable fibrinolysis inhibitor) inhibition stimulates the fibrinolytic rate in different invitro models 羧肽酶U (CPU，羧肽酶B2，活化的凝血酶激活的纤维蛋白溶解抑制剂) 抑制在不同的体外模型中刺激纤维蛋白溶解率 Leenaerts, D.; Loyau, S.; Mertens, J. C.; Boisseau, W.; Michel, J. B.; Lambeir, A. M.; Jandrot-Perrus, M.; Hendriks, D. 分享 收藏
Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome Ceuleers, Hannah; Hanning, Nikita; Heirbaut, Jelena; Van Remoortel, Samuel; Joossens, Jurgen; Van der Veken, Pieter; Francque, Sven M.; De Bruyn, Michelle; Lambeir, Anne-Marie; De Man, Joris G.; Timmermans, Jean-Pierre; Augustyns, Koen; De Meester, Ingrid; De Winter, Benedicte Y. 分享 收藏
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