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J

John R. Traynor

university of michigan

48H指数
336论文数
9.4K被引数
收录论文 104
发表时间
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High potency μ-opioid receptor agonists engage sodium-bound receptor states高活性μ-阿片受体激动剂激活钠离子结合的受体状态
errMolecular Pharmacology
IF3
err2026-08-24
err0
errOAAI
errAlexander J. Powell; Nicholas W. Griggs; Jorge A. Iñiguez-Lluhí; Henry I. Mosberg; John R. Traynor
err分享
err收藏
PN6047 demonstrates preclinical efficacy in headache models as a novel delta-opioid receptor agonistPN6047作为新型δ-阿片受体激动剂在头痛模型中表现出临床前疗效
errJournal of Headache and Pain
IF7.9
err2026-08-06
err0
errOAAI
errYaseen Awad-Igbaria; Yanping Zhang; Mattin Aframian; Guido C. Faas; Andrew Charles; Serapio M. Baca; Emily Jutkiewicz; Bengt von Mentzer; John Traynor; David Kendall; Amynah A. Pradhan
err分享
err收藏
Positive allosteric modulation of the delta opioid receptor attenuates depression-like and pain-like behaviors but does not promote convulsionsδ阿片受体正构变构调节可减轻抑郁样和疼痛样行为，但不诱发惊厥
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-07-01
err0
PREAI
errJutkiewicz, Emily M.; Palleiko, Benjamin A.; Dripps, Isaac J.; Livingston, Kathryn E.; Roques, Bernard P.; Clements, Benjamin M.; Traynor, John R.
err分享
err收藏
Synthesis and evaluation of 14β-acyl substituted 17-cyclopropylmethyl-7; 8-dihydromorphinone derivatives: mixed partial agonists at mu opioid and nociception/orphanin FQ peptide receptors14β-酰基取代的17-环丙基甲基-7,8-二氢吗啡酮衍生物的合成与评价：μ阿片和 nociception/orphanin FQ 肽受体的混合部分激动剂
errrsc med. chem.
IF0
err2026-04-17
err0
errOAAI
errMehrnoosh Ostovar; Keith Olsen; Gerta Cami-Kobeci; John R. Traynor; Luka Jeramaz; Stewart B. Kirton; Stephen M. Husbands
err分享
err收藏
A Mu-Opioid Receptor Positive Allosteric Modulator Provides Opioid-Sparing Antinociception Without Enhancing Opioid Side-Effectsμ-阿片受体正性别构调节剂在提供阿片类镇痛作用的同时，不增强阿片类药物的副作用。
errthe journal of pharmacology and experimental therapeutics
IF0
err2026-02-18
err0
PREAI
errKelsey E. Kochan; Benjamin M. Clements; Thomas D. Prince; Catherine Demery; Andrew D. White; Erica S. Levitt; John R. Traynor
err分享
err收藏
Effects of Two Structurally Diverse Positive Allosteric Modulators on Signaling Bias at the Mu-Opioid Receptor.两种结构多样的阳性别构调节剂对μ-阿片受体信号偏倚的影响。
errMolecular Pharmacology
IF3
err2025-09-26
err0
PREAI
errMengchu Li; Kelsey E. Kochan; M.Alexander Stanczyk; Hannah C. Stewart; Joshua L. West; Andrew D. White; Zara Y. Weinberg; Manojkumar A. Puthenveedu; John R. Traynor
err分享
err收藏
Xylazine exacerbates fentanyl-induced respiratory depression and bradycardia盐酸氯胺酮加剧芬太尼引起的呼吸抑制和心动过缓
errpharmacology and experimental therapeutics
IF0
err2025-05-27
err0
PREAI
errCatherine Demery; Sierra C. Moore; Erica S. Levitt; Jessica P. Anand; John R. Traynor
err分享
err收藏
The MU Opioid Receptor Positive Allosteric Modulator BMS-986122 Attenuates Opioid Tolerance and Withdrawalμ阿片受体正变构调节剂BMS-986122减轻阿片耐受和戒断症状
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errJessup, Dawn; Traynor, John R.
err分享
err收藏
Molecular Mechanisms of Positive Allosteric Modulation of the μ-Opioid Receptorμ-阿片受体正变构调节的分子机制
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errClements, Benjamin; Traynor, John R.
err分享
err收藏
Structure-Activity Relationships and Molecular Pharmacology of Positive Allosteric Modulators of the Mu-Opioid Receptor
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-12-11
err0
PREAI
errLi, Mengchu; Gan, Xinmin; Liu, Kun; Walajapet, Rajeswaran; Stanczyk, M. Alex; Stewart, Hannah C.; Rech, Jason C.; White, Andrew D.; Traynor, John R.
err分享
err收藏
Structure-Activity Relationships of the Fentanyl Scaffold: Identification of Antagonists as Potential Opioid Overdose Reversal Agents (vol 15, pg 2830, 2024)
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-09-18
err0
PREAI
errAnand, Jessica P.; Moore, Sierra C.; Dixon, Emma E.; Naccarato, Carmelita M. Perrien; West, Joshua L.; Delong, Lennon J.; Burgess, Emily; Twarozynski, Jack J.; Traynor, John R.
err分享
err收藏
Structure-Activity Relationships of the Fentanyl Scaffold: Identification of Antagonists as Potential Opioid Overdose Reversal Agents
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-07-12
err1
errOAAI
errAnand, Jessica P.; Moore, Sierra C.; Dixon, Emma E.; Perrien Naccarato, Carmelita M.; West, Joshua L.; Delong, Lennon J.; Burgess, Emily; Twarozynski, Jack J.; Traynor, John R.
err分享
err收藏
Positive Allosteric Modulation of the Mu Opioid Receptor Does Not Potentiate Opioid-Mediated Side Effects
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err1
errOAAI
errKochan, Kelsey; Prince, Thomas; Traynor, John
err分享
err收藏
Structure-activity Exploration of Positive Allosteric Modulators of the Mu-opioid Receptor
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errLi, Mengchu; Traynor, John; Zhang, Sherrice; Stanczyk, Matthew; Gan, Xinmin; White, Andrew
err分享
err收藏
Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G Protein-Coupled Receptors
errMOLECULAR PHARMACOLOGY
IF3
err2023-05-01
err4
PREAI
errChan, Wallace K. B.; Carlson, Heather A.; Traynor, John R.
err分享
err收藏
Delta Opioid Receptor-Mediated Antidepressant-Like Effects of Diprenorphine in Mice
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-03-01
err4
errOAAI
errOlson, Keith M.; Hillhouse, Todd M.; Burgess, Gwendolyn E.; West, Joshua L.; Hallahan, James E.; Dripps, Isaac J.; Ladetto, Allison G.; Rice, Kenner C.; Jutkiewicz, Emily M.; Traynor, John R.
err分享
err收藏
Opioid research in the time of the opioid crisis
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2023-02-22
err2
errOAAI
errTraynor, John R. R.; Moron, Jose A. A.
err分享
err收藏
PACAP and acetylcholine cause distinct Ca2+ signals and secretory responses in chromaffin cells
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2022-12-20
err5
errOAAI
errMorales, Alina; Mohan, Ramkumar; Chen, Xiaohuan; Coffman, Breanna L.; Bendahmane, Mounir; Watch, Lester; West, Joshua L.; Bakshi, Shreeya; Traynor, John R.; Giovannucci, David R.; Kammermeier, Paul J.; Axelrod, Daniel; Currie, Kevin P. M.; Smrcka, Alan V.; Anantharam, Arun
err分享
err收藏
Opioid Antagonists from the Orvinol Series as Potential Reversal for Overdose
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-10-12
err4
errOAAI
errDisney, Alex; Olson, Keith M.; Shafer, Amanda M.; Moore, Sierra C.; Anand, Jessica P.; Traynor, John R.; Husbands, Stephen M.
err分享
err收藏
Structure Activity Relationships of Illicit Fentanyl Analogs
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errMoore, Sierra; Anand, Jess; Dixon, Emma; Perrien-Naccarrato, Carmelita; Traynor, John R.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
A
Arthur Christopoulos
H 指数: 95 · 论文数: 1.9K
K
Kenner C. Rice
H 指数: 85 · 论文数: 1.0K
M
MacDonald J. Christie
H 指数: 78 · 论文数: 2.7K
B
Bernárd P. Roques
H 指数: 77 · 论文数: 576
L
Lakshmi A. Devi
H 指数: 74 · 论文数: 354
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