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J

Joaquín Fernández-Irigoyen

Navarre Institute of Health Research
H指数:31
被引数:3,113

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Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α-synuclein preformed fibrils-induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

嗅觉蛋白质组学揭示了HDAC1抑制剂pyroxamide能够阻止α-突触核蛋白预形成原纤维在鼻上皮细胞、小胶质细胞和多巴胺能神经元细胞系中引起的损伤

Brain Pathology
IF6.2
2026-09-160
OAAI
Paz Cartas-Cejudo; Marina De Miguel; Leire Extramiana; Mercedes Lachén-Montes; Silvia Romero-Murillo; Djordje Gveric; Joaquín Fernández-Irigoyen; Enrique Santamaría
Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

线粒体移植作为一种新的治疗策略，用于对抗心肌梗死雄性大鼠的心脏和肾脏后果

Acta Physiologica
IF5.6
2026-04-250
OAAI
María Cuesta-Corral; Alejandro Montoro-Garrido; Ana Romero-Miranda; Fabián Islas; Bunty Ramchandani; Ricardo Gredilla; Joaquín Fernández-Irigoyen; Enrique Santamaría; Beatriz Delgado-Valero; Sara Jiménez-González; Raquel Rodrigues Díez; María Luisa Nieto; Victoria Cachofeiro; Ernesto Martínez-Martínez
Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

脑脊液(CSF)在诊断时的蛋白质组学特征决定了肌萎缩侧索硬化症(amyotrophic lateral sclerosis)的进展和生存：CXCL7水平在疾病预后和生存中的作用

Brain Pathology
IF6.2
2026-03-030
OAAI
Sergio Roca-Pereira; Yaiza López-Sampere; Pol Mengod-Soler; Mario Peña-Fonteboa; Carla Marco; Alejandro Caravaca-Puchades; Raúl Domínguez; Juan Francisco Vázquez-Costa; Enrique Santamaría; Joaquín Fernández-Irigoyen; María J. Colomina; Isabel León Moreno; Antonio Martínez Yélamos; Sergio Martínez Yélamos; Gabriel Santpere; Elia Obis; Manuel Portero-Otín; Gerard Piñol-Ripoll; Mónica Povedano; Pol Andrés-Benito
4R-tau seeding activity reveals molecular subtypes in progressive supranuclear palsy

4R-tau种子活性揭示了进行性核上性麻痹的分子亚型

Nature Communications
IF15.7
2025-12-310
OAAI
Ivan Martinez-Valbuena; Seojin Lee; Enrique Santamaria; Joaquín Fernández-Irigoyen; Shelley L. Forrest; Silvia Zampar; Jun Li; Hidetomo Tanaka; Blas Couto; Nikolai Gil D. Reyes; Syeda Hania Qamar; Ali M. Karakani; Ain Kim; Konstantin Senkevich; Ekaterina Rogaeva; Susan H. Fox; M. Carmela Tartaglia; Naomi P. Visanji; Martin Ingelsson; Tallulah Andrews; Anthony E. Lang; Gabor G. Kovacs
Establishment and characterization of an orthotopic implanted lung cancer model to mimic human tumor structure, microenvironment, and metastatic spread

建立并表征一种同位移植的肺癌模型，以模拟人类肿瘤结构、微环境及转移扩散。

TRANSLATIONAL LUNG CANCER RESEARCH
IF3.5
2025-11-300
PRE
Picabea, Benat; Orive, Daniel; Rodriguez, Covadonga; Mailharin, Miren; Sanguesa, Maria; Houry, Maeva; Arricibita, Andrea; Echepare, Mirari; Alava, Ane; Viu-Idocin, Cristina; Calvo, Alfonso; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Ariz, Mikel; Montuenga, Luis M.; Valencia, Karmele
Photoactivated adenylyl cyclase in cortical astrocytes promotes synaptic potentiation and reveals alterations in Huntington’s Disease

皮层星形胶质细胞中的光激活腺苷酸环化酶促进突触增强，并揭示了亨廷顿病中的改变

iScience
IF4.1
2025-09-240
OAAI
Laia Sitjà-Roqueta; Neville M. Ngum; Evgenii Zherebstov; Melike Küçükerden; Maryam Givehchi; Valentina Bova; Francis Delicata; Elena Anaya-Cubero; Enrique Santamaria; Joaquín Fernández-Irigoyen; Sara Conde-Berriozabal; Anna Castañé; Sergei Sokolovski; Edik Rafailov; Manuel J. Rodríguez; Jordi Alberch; Deniz Dalkara; Andreas Möglich; Alexander Bykov; Igor Meglinski; H.Rheinallt Parri; Mercè Masana
ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer

ONECUT2 重编程神经内分泌命运，并且是小细胞肺癌中可操作的 therapeutic target。

Molecular Medicine
IF6.4
2025-06-110
OAAI
Mirian Gutiérrez; Irene Zamora; Raquel Iriarte; María José Pajares; Qian Yang; Chen Qian; Nerea Otegui; Joaquín Fernández-Irigoyen; Enrique Santamaría; Nicolas Alcala; Alexandra Sexton-Oates; Lynnette Fernández-Cuesta; Miguel Barajas; Alfonso Calvo; Luis M. Montuenga; Beatrice Knudsen; Sungyong You; Michael R. Freeman; Ignacio Encío; Mirja Rotinen
Microglial SIRT2 deficiency aggravates cognitive decline and amyloid pathology in Alzheimer’s disease

小胶质细胞SIRT2缺乏会加剧阿尔茨海默病中的认知衰退和淀粉样蛋白病理。

brain behavior and immunity
IF0
2025-06-090
OA
Noemi Sola-Sevilla; Maider Garmendia-Berges; Mikel Aleixo; MCarmen Mera-Delgado; Maite Solas; Rosa M. Tordera; Lucía García-Carracedo; Sara Expósito; Elena Anaya-Cubero; Joaquín Fernández-Irigoyen; Elisabeth Guruceaga; Enrique Santamaria; Eduardo D. Martin; Elena Puerta
Development of human targeted extracellular vesicles loaded with shRNA minicircles to prevent parkinsonian pathology

开发靶向人类的外泌体，负载shRNA微环以预防帕金森病病理变化

TRANSLATIONAL NEURODEGENERATION
IF15.2
2025-05-260
OA
Izco, Maria; Sola, Carlos; Schleef, Martin; Schmeer, Marco; de Toro, Maria; Verona, Guglielmo; Carlos, Estefania; Reinares-Sebastian, Alejandro; Colina, Sandra; Marzo-Sola, Maria Eugenia; Garcia-Sanmartin, Josune; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Mugica-Vidal, Rodolfo; Blesa, Javier; Alvarez-Erviti, Lydia
Impact of medication use on olfactory performance in older adults

药物使用对老年人嗅觉功能的影响

FRONTIERS IN PUBLIC HEALTH
IF3.4
2025-04-030
OA
Izco-Cubero, Maite; Zambom-Ferraresi, Fabiola; Zambom-Ferraresi, Fabricio; de la Riva, Maria Luisa Fernandez Gonzalez; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Lachen-Montes, Mercedes; Lasarte, Juan Jose; Uzcanga-Lacabe, Maria; Fernandez, Secundino; San Martin, Gloria Sanjurjo; Maravi-Aznar, Enrique
Alterations of the IKZF1-IKZF2 tandem in immune cells of schizophrenia patients regulate associated phenotypes
JOURNAL OF NEUROINFLAMMATION
IF10.1
2024-12-180
OAAI
Ballasch, Ivan; Lopez-Molina, Laura; Galan-Ganga, Marcos; Sancho-Balsells, Anna; Rodriguez-Navarro, Irene; Borras-Pernas, Sara; Rabadan, M. Angeles; Chen, Wanqi; Pasto-Pellicer, Carlota; Flotta, Francesca; Wang, Maoyu; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Aguilar, Ruth; Dobano, Carlota; Egri, Natalia; Hernandez, Carla; Alfonso, Miqueu; Juan, Manel; Alberch, Jordi; del Toro, Daniel; Arranz, Belen; Canals, Josep M.; Giralt, Albert
DSTYK Inhibition Sensitizes NSCLC to Taxane-Based Chemotherapy

DSTYK抑制增强了非小细胞肺癌对紫杉烷类化疗的敏感性

JOURNAL OF THORACIC ONCOLOGY
IF20.8
2024-11-010
PRE
Echepare, Mirari; Picabea, Benat; Arricibita, Andrea; Teijeira, Alvaro; Pasquier, Andrea; Zandueta, Carolina; Otegui, Nerea; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Romero, Octavio; Sanchez-Cespedes, Montse; Lecanda, Fernando; Hernandez, Javier; Felip, Enriqueta; Provencio, Mariano; Facchinetti, Federica; Roz, Luca; Montuenga, Luis M.; Valencia, Karmele
Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis

星形胶质细胞GLUT1减少矛盾地改善了中枢和外周葡萄糖稳态

SCIENCE ADVANCES
IF12.5
2024-10-180
OAAI
Ardanaz, Carlos G.; de la Cruz, Aida; Minhas, Paras S.; Hernandez-Martin, Nira; Pozo, Miguel Angel; Valdecantos, M. Pilar; Valverde, Angela M.; Villa-Valverde, Palmira; Elizalde-Horcada, Marcos; Puerta, Elena; Ramirez, Maria J.; Ortega, Jorge E.; Urbiola, Ainhoa; Ederra, Cristina; Ariz, Mikel; Ortiz-de-Solorzano, Carlos; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Karsenty, Gerard; Bruning, Jens C.; Solas, Maite
TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition
ACTA NEUROPATHOLOGICA
IF9.3
2024-09-210
OAAI
Torres, Pascual; Rico-Rios, Santiago; Ceron-Codorniu, Miriam; Santacreu-Vilaseca, Marta; Seoane-Miraz, David; Jad, Yahya; Ayala, Victoria; Marino, Guillermo; Beltran, Maria; Miralles, Maria P.; Andres-Benito, Pol; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Lopez-Otin, Carlos; Soler, Rosa M.; Povedano, Monica; Ferrer, Isidro; Pamplona, Reinald; Wood, Matthew J. A.; Varela, Miguel A.; Portero-Otin, Manuel

研究方向

暂未获取到该数据
E
Enrique Santamaría
H 指数:33论文数:249被引数:4,234
M
Mercedes Lachén‐Montes
H 指数:15论文数:61被引数:759
K
Karina Ausín
H 指数:16论文数:47被引数:788
I
Isidró Ferrer
H 指数:119论文数:1,173被引数:5.9万
F
Fernando J. Corrales
H 指数:50论文数:323被引数:9,465
N
Nicolás Martínez‐Velilla
H 指数:34论文数:289被引数:4,586
P
Paz Cartas‐Cejudo
H 指数:6论文数:34被引数:185
F
Fabrício Zambom-Ferraresi
H 指数:26论文数:97被引数:3,327
A
Amaya Fernández‐Celis
H 指数:26论文数:79被引数:1,760
M
Míkel Izquierdo
H 指数:99论文数:800被引数:3.7万