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p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells p53增强DNA修复，并抑制衰老细胞中的细胞质染色质片段和炎症。 Miller, Karl N.; Li, Brightany; Pierce-Hoffman, Hannah R.; Patel, Shreeya; Lei, Xue; Rajesh, Adarsh; Teneche, Marcos G.; Havas, Aaron P.; Gandhi, Armin; Macip, Carolina Cano; Lyu, Jun; Victorelli, Stella G.; Woo, Seung-Hwa; Lagnado, Anthony B.; Laporta, Michael A.; Liu, Tianhui; Dasgupta, Nirmalya; Li, Sha; Davis, Andrew; Korotkov, Anatoly; Hultenius, Erik; Gao, Zichen; Altman, Yoav; Porritt, Rebecca A.; Garcia, Guillermina; Mogler, Carolin; Seluanov, Andrei; Gorbunova, Vera; Kaech, Susan M.; Tian, Xiao; Dou, Zhixun; Chen, Chongyi; Passos, Joao F.; Adams, Peter D. 分享 收藏
Senescent cell transplantation into the skin induces age-related peripheral dysfunction and cognitive decline 皮肤衰老细胞移植诱导与年龄相关的外周功能障碍和认知功能下降 Franco, Ana Catarina; Martini, Helene; Victorelli, Stella; Lagnado, Anthony B.; Wyles, Saranya P.; Rowsey, Jennifer L.; Pirius, Nicholas; Woo, Seung-Hwa; Costa, Daniela G.; Chaib, Selim; Tullius, Stefan G.; Tchkonia, Tamar; Kirkland, James L.; Khosla, Sundeep; Jurk, Diana; Cavadas, Claudia; Passos, Joao F. 分享 收藏
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The Third Annual Symposium of the Midwest Aging Consortium Keller, Andrea; Bai, Hua; Budinger, Scott; Eliazer, Susan; Hansen, Malene; Konopka, Adam R.; Morales-Nebreda, Luisa; Najt, Charles P.; Prahlad, Veena; Victorelli, Stella; Vorland, Colby J.; Yuan, Rong; Rhoads, Timothy W.; Mihaylova, Maria M. 分享 收藏
Spatial mapping of cellular senescence: emerging challenges and opportunities 细胞衰老的空间图谱: 新出现的挑战和机遇 Gurkar, Aditi U.; Gerencser, Akos A.; Mora, Ana L.; Nelson, Andrew C.; Zhang, Anru R.; Lagnado, Anthony B.; Enninful, Archibald; Benz, Christopher; Furman, David; Beaulieu, Delphine; Jurk, Diana; Thompson, Elizabeth L.; Wu, Fei; Rodriguez, Fernanda; Barthel, Grant; Chen, Hao; Phatnani, Hemali; Heckenbach, Indra; Chuang, Jeffrey H.; Horrell, Jeremy; Petrescu, Joana; Alder, Jonathan K.; Lee, Jun Hee; Niedernhofer, Laura J.; Kumar, Manoj; Konigshoff, Melanie; Bueno, Marta; Sokka, Miiko; Scheibye-Knudsen, Morten; Neretti, Nicola; Eickelberg, Oliver; Adams, Peter D.; Hu, Qianjiang; Zhu, Quan; Porritt, Rebecca A.; Dong, Runze; Peters, Samuel; Victorelli, Stella; Pengo, Thomas; Khaliullin, Timur; Suryadevara, Vidyani; Fu, Xiaonan; Bar-Joseph, Ziv; Ji, Zhicheng; Passos, Joao F. 分享 收藏
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Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer Millar, Fraser R.; Pennycuick, Adam; Muir, Morwenna; Quintanilla, Andrea; Hari, Priya; Freyer, Elisabeth; Gautier, Philippe; Meynert, Alison; Grimes, Graeme; Coll, Carla Salomo; Zdral, Sofia; Victorelli, Stella; Teixeira, Vitor H.; Connelly, John; Passos, Joao F.; Ros, Marian A.; Wallace, William A. H.; Frame, Margaret C.; Sims, Andrew H.; Boulter, Luke; Janes, Sam M.; Wilkinson, Simon; Acosta, Juan Carlos 分享 收藏
Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner 中性粒细胞以ROS依赖的方式诱导旁分泌端粒功能障碍和衰老 Lagnado, Anthony; Leslie, Jack; Ruchaud-Sparagano, Marie-Helene; Victorelli, Stella; Hirsova, Petra; Ogrodnik, Mikolaj; Collins, Amy L.; Vizioli, Maria Grazia; Habiballa, Leena; Saretzki, Gabriele; Evans, Shane A.; Salmonowicz, Hanna; Hruby, Adam; Geh, Daniel; Pavelko, Kevin D.; Dolan, David; Reeves, Helen L.; Grellscheid, Sushma; Wilson, Colin H.; Pandanaboyana, Sanjay; Doolittle, Madison; von Zglinicki, Thomas; Oakley, Fiona; Gallage, Suchira; Wilson, Caroline L.; Birch, Jodie; Carroll, Bernadette; Chapman, James; Heikenwalder, Mathias; Neretti, Nicola; Khosla, Sundeep; Masuda, Claudio Akio; Tchkonia, Tamar; Kirkland, James L.; Jurk, Diana; Mann, Derek A.; Passos, Joao F. 分享 收藏
Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice Ogrodnik, Mikolaj; Evans, Shane A.; Fielder, Edward; Victorelli, Stella; Kruger, Patrick; Salmonowicz, Hanna; Weigand, Bettina M.; Patel, Ayush D.; Pirtskhalava, Tamar; Inman, Christine L.; Johnson, Kurt O.; Dickinson, Stephanie L.; Rocha, Azucena; Schafer, Marissa J.; Zhu, Yi; Allison, David B.; von Zglinicki, Thomas; LeBrasseur, Nathan K.; Tchkonia, Tamar; Neretti, Nicola; Passos, Joao F.; Kirkland, James L.; Jurk, Diana 分享 收藏
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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease (vol 47, pg 446, 2019) Hickson, Latonya J.; Prata, Larissa G. P. Langhi; Bobart, Shane A.; Evans, Tamara K.; Giorgadze, Nino; Hashmi, Shahrukh K.; Herrmann, Sandra M.; Jensen, Michael D.; Jia, Qingyi; Jordan, Kyra L.; Kellogg, Todd A.; Khosla, Sundeep; Koerber, Daniel M.; Lagnado, Anthony B.; Lawson, Donna K.; LeBrasseur, Nathan K.; Lerman, Lilach O.; McDonald, Kathleen M.; McKenzie, Travis J.; Passos, Joao F.; Pignolo, Robert J.; Pirtskhalava, Tamar; Saadiq, Ishran M.; Schaefer, Kalli K.; Textor, Stephen C.; Victorelli, Stella G.; Volkman, Tammie L.; Xue, Ailing; Wentworth, Mark A.; Gerdes, Erin O. Wissler; Allison, David B.; Dickinson, Stephanie L.; Ejima, Keisuke; Atkinson, Elizabeth J.; Lenburg, Marc; Zhu, Yi; Tchkonia, Tamara; Kirkland, James L. 分享 收藏
Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction Victorelli, Stella; Lagnado, Anthony; Halim, Jessica; Moore, Will; Talbot, Duncan; Barrett, Karen; Chapman, James; Birch, Jodie; Ogrodnik, Mikolaj; Meves, Alexander; Pawlikowski, Jeff S.; Jurk, Diana; Adams, Peter D.; van Heemst, Diana; Beekman, Marian; Slagboom, P. Eline; Gunn, David A.; Passos, Joao F. 分享 收藏
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease Hickson, LaTonya J.; Prata, Larissa G. P. Langhi; Bobart, Shane A.; Evans, Tamara K.; Giorgadze, Nino; Hashmi, Shahrukh K.; Herrmann, Sandra M.; Jensen, Michael D.; Jia, Qingyi; Jordan, Kyra L.; Kellogg, Todda.; Khosla, Sundeep; Koerber, Daniel M.; Lagnado, Anthony B.; Lawson, Donna K.; LeBrasseur, Nathan K.; Lerman, Lilach O.; McDonald, Kathleen M.; McKenzie, Travis J.; Passos, Joao F.; Pignolo, Robert J.; Pirtskhalava, Tamar; Saadiq, Ishran M.; Schaefer, Kalli K.; Textor, Stephen C.; Victorelli, Stella G.; Volkman, Tammie L.; Xue, Ailing; Wentworth, Mark A.; Gerdes, Erin O. Wissler; Zhu, Yi; Tchkonia, Tamara; Kirkland, James L. 分享 收藏
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis (vol 29, pg 1061, 2019) Ogrodnik, Mikolaj; Zhu, Yi; Langhi, Larissa G. P.; Tchkonia, Tamar; Kruger, Patrick; Fielder, Edward; Victorelli, Stella; Ruswhandi, Rifqha A.; Giorgadze, Nino; Pirtskhalava, Tamar; Podgorni, Oleg; Enikolopov, Grigori; Johnson, Kurt O.; Xu, Ming; Inman, Christine; Palmer, Allyson K.; Schafer, Marissa; Weigl, Moritz; Ikeno, Yuji; Burns, Terry C.; Passos, Joao F.; von Zglinicki, Thomas; Kirkland, James L.; Jurk, Diana 分享 收藏
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis Ogrodnik, Mikolaj; Zhu, Yi; Langhi, Larissa G. P.; Tchkonia, Tamar; Kruger, Patrick; Fielder, Edward; Victorelli, Stella; Ruswhandi, Rifqha A.; Giorgadze, Nino; Pirtskhalava, Tamar; Podgorni, Oleg; Enikolopov, Grigori; Johnson, Kurt O.; Xu, Ming; Inman, Christine; Palmer, Allyson K.; Schafer, Marissa; Weigl, Moritz; Ikeno, Yuji; Burns, Terry C.; Passos, Joao F.; von Zglinicki, Thomas; Kirkland, James L.; Jurk, Diana 分享 收藏
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