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Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition Schepers, Melissa; Hendrix, Sven; Mussen, Femke; van Breedam, Elise; Ponsaerts, Peter; Lemmens, Stefanie; Hellings, Niels; Ricciarelli, Roberta; Fedele, Ernesto; Bruno, Olga; Brullo, Chiara; Prickaerts, Jos; Van Broeckhoven, Jana; Vanmierlo, Tim 分享 收藏
Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice 磷酸二酯酶4B (PDE4B) 的早期抑制在APPswe/PS1dE9小鼠中灌输认知弹性 Rombaut, Ben; Schepers, Melissa; Tiane, Assia; Mussen, Femke; Koole, Lisa; Kessels, Sofie; Trippaers, Chloe; Jacobs, Ruben; Wouters, Kristiaan; Willems, Emily; van Veggel, Lieve; Koulousakis, Philippos; Deluyker, Dorien; Bito, Virginie; Prickaerts, Jos; Wens, Inez; Brone, Bert; van den Hove, Daniel L. A.; Vanmierlo, Tim 分享 收藏
Beta-amyloid interacts with and activates the long-form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability Sin, Yuan Yan; Cameron, Ryan T.; Schepers, Melissa; Macleod, Ruth; Wright, Tom A.; Paes, Dean; van den Hove, Daniel; Willems, Emily; Vanmierlo, Tim; Prickaerts, Jos; Blair, Connor M.; Baillie, George S. 分享 收藏
The Reliability and Clinical Validation of Automatically-Derived Verbal Memory Features of the Verbal Learning Test in Early Diagnostics of Cognitive Impairment Possemis, Nina; ter Huurne, Daphne; Banning, Leonie; Gruters, Angelique; Van Asbroeck, Stephanie; Koenig, Alexandra; Linz, Nicklas; Troeger, Johannes; Langel, Kai; Blokland, Arjan; Prickaerts, Jos; de Vugt, Marjolein; Verhey, Frans; Ramakers, Inez 分享 收藏
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Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology Paes, Dean; Schepers, Melissa; Willems, Emily; Rombaut, Ben; Tiane, Assia; Solomina, Yevgeniya; Tibbo, Amy; Blair, Connor; Kyurkchieva, Elka; Baillie, George S.; Ricciarelli, Roberta; Brullo, Chiara; Fedele, Ernesto; Bruno, Olga; van den Hove, Daniel; Vanmierlo, Tim; Prickaerts, Jos 分享 收藏
From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions Tiane, Assia; Schepers, Melissa; Reijnders, Rick A.; van Veggel, Lieve; Chenine, Sarah; Rombaut, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; Hellings, Niels; van den Hove, Daniel; Vanmierlo, Tim 分享 收藏
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Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice Kerkhofs, Danielle; Helgers, Robin; Hermes, Denise; Steinbusch, Hellen P. J.; Van Essen, Helma; Leenders, Peter; Prickaerts, Jos; Staals, Julie; Biessen, Erik A.; Van Oostenbrugge, Robert J.; Foulquier, Sebastien 分享 收藏
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Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis Schepers, Melissa; Paes, Dean; Tiane, Assia; Rombaut, Ben; Piccart, Elisabeth; van Veggel, Lieve; Gervois, Pascal; Wolfs, Esther; Lambrichts, Ivo; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; van Schaik, Pauline; Baron, Wia; Lefevere, Evy; Wasner, Kobi; Grunewald, Anne; Verfaillie, Catherine; Baeten, Paulien; Broux, Bieke; Wieringa, Paul; Hellings, Niels; Prickaerts, Jos; Vanmierlo, Tim 分享 收藏
The value of maintaining cognition in patients with mild cognitive impairment: The innovation headroom and potential cost-effectiveness of roflumilast 轻度认知障碍患者维持认知的价值: 罗氟司特的创新空间和潜在成本效益 Handels, Ron; Grimm, Sabine; Blokland, Arjan; Possemis, Nina; Ramakers, Inez; Sambeth, Anke; Verhey, Frans; Vos, Stephanie; Joore, Manuela; Prickaerts, Jos; Jonsson, Linus 分享 收藏
Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling Calis, Dila; Hess, Morgan; Marchetta, Philine; Singer, Wibke; Modro, Julian; Nelissen, Ellis; Prickaerts, Jos; Sandner, Peter; Lukowski, Robert; Ruth, Peter; Knipper, Marlies; Ruettiger, Lukas 分享 收藏
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