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C

Christiane D. Wrann

Massachusetts General Hospital and Harvard Medical School
H指数:29
被引数:7,477

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The exercise hormone irisin has neuroprotective effects in a mouse model of multiple sclerosis

运动激素鸢尾素在多发性硬化小鼠模型中具有神经保护作用

Nature Metabolism
IF20.8
2026-05-210
OAAI
Sina C. Rosenkranz; Joana F. da Rocha; Luis Moreira; Pius Schlachter; Jasmina Bier; Kaela Healy; Daniela Neves Silva; Mohamed Ariff Iqbal; Marjan Gharagozloo; Yueyue Xiong; Matthew A. Murphy; Helena C. Lichtenfeld; Lukas Raich; Michaela Schweizer; Asude Ertaş; Marcel S. Woo; Vanessa Vieira; Samuel E. Honeycutt; James P. White; Gregory A. Wyant; Manuel A. Friese; Peter A. Calabresi; Ruxandra F. Sîrbulescu; Christiane D. Wrann
Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing

阿尔茨海默病小鼠模型齿状回中保护性运动反应的单核RNA测序揭示

Nature Neuroscience
IF20
2025-06-120
PRE
Joana F. da Rocha; Michelle L. Lance; Renhao Luo; Pius Schlachter; Luis Moreira; Mohamed Ariff Iqbal; Paula Kuhn; Robert S. Gardner; Sophia Valaris; Mohammad R. Islam; Gabriele M. Gassner; Sofia Mazuera; Kaela Healy; Sanjana Shastri; Nathaniel B. Hibbert; Kristen V. Moran-Figueroa; Erin B. Haley; Ryan D. Pfeiffer; Sema Aygar; Ksenia V. Kastanenka; Logan Brase; Oscar Harari; Bruno A. Benitez; Nathan R. Tucker; Christiane D. Wrann
Irisin reduces amyloid-D by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling

Irisin通过诱导ERK-STAT3信号下调后星形胶质细胞释放中性溶酶来减少淀粉样蛋白D

NEURON
IF15
2023-11-0131
OA
Kim, Eunhee; Kim, Hyeonwoo; Jedrychowski, Mark P.; Bakiasi, Grisilda; Park, Joseph; Kruskop, Jane; Choi, Younjung; Kwak, Sang Su; Quinti, Luisa; Kim, Doo Yeon; Wrann, Christiane D.; Spiegelman, Bruce M.; Tanzi, Rudolph E.; Choi, Se Hoon
Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin

irisin改善病理性 α-突触核蛋白诱导的帕金森氏病

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-08-3152
OAAI
Kam, Tae-In; Park, Hyejin; Chou, Shih-Ching; Van Vranken, Jonathan G.; Mittenbuhler, Melanie J.; Kim, Hyeonwoo; Mu, A.; Choi, Yu Ree; Biswas, Devanik; Wang, Justin; Shin, Yu; Loder, Alexis; Karuppagounder, Senthilkumar S.; Wrann, Christiane D.; Dawson, Valina L.; Spiegelman, Bruce M.; Dawson, Ted M.
Treadmill Exercise During Cerebral Hypoperfusion Has Only Limited Effects on Cognitive Function in Middle-Aged Subcortical Ischemic Vascular Dementia Mice

脑低灌注期间的跑步机运动对中年皮质下缺血性血管性痴呆小鼠的认知功能影响有限

FRONTIERS IN AGING NEUROSCIENCE
IF4.5
2021-12-215
OAAI
Ohtomo, Ryo; Ishikawa, Hidehiro; Kinoshita, Keita; Chung, Kelly K.; Hamanaka, Gen; Ohtomo, Gaku; Takase, Hajime; Wrann, Christiane D.; Katsuki, Hiroshi; Iwata, Atsushi; Lok, Josephine; Lo, Eng H.; Arai, Ken
Exercise hormone irisin is a critical regulator of cognitive function (vol 3, pg 1058, 2021)
NATURE METABOLISM
IF20.8
2021-10-075
OA
Islam, Mohammad R.; Valaris, Sophia; Young, Michael F.; Haley, Erin B.; Luo, Renhao; Bond, Sabrina F.; Mazuera, Sofia; Kitchen, Robert R.; Caldarone, Barbara J.; Bettio, Luis E. B.; Christie, Brian R.; Schmider, Angela B.; Soberman, Roy J.; Besnard, Antoine; Jedrychowski, Mark P.; Kim, Hyeonwoo; Tu, Hua; Kim, Eunhee; Choi, Se Hoon; Tanzi, Rudolph E.; Spiegelman, Bruce M.; Wrann, Christiane D.
G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

G蛋白偶联受体56调节机械超负荷诱导的肌肉肥大

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2014-10-21103
OAAI
White, James P.; Wrann, Christiane D.; Rao, Rajesh R.; Nair, Sreekumaran K.; Jedrychowski, Mark P.; You, Jae-Sung; Martinez-Redondo, Vicente; Gygi, Steven P.; Ruas, Jorge L.; Hornberger, Troy A.; Wu, Zhidan; Glass, David J.; Piao, Xianhua; Spiegelman, Bruce M.

研究方向

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B
Bruce M. Spiegelman
H 指数:186论文数:472被引数:18.2万
M
Mohammad Rashedul Islam
H 指数:12论文数:50被引数:726
H
Hyeonwoo Kim
H 指数:14论文数:51被引数:2,035
M
Mark P. Jedrychowski
H 指数:65论文数:211被引数:3.3万
N
Niels C. Riedemann
H 指数:47论文数:99被引数:8,329
S
Sophia Valaris
H 指数:7论文数:18被引数:627
C
Christian Krettek
H 指数:82论文数:1,376被引数:3.2万
A
Anthony Rosenzweig
H 指数:82论文数:319被引数:2.7万
C
Christopher Nguyen
H 指数:31论文数:313被引数:3,534
R
Ryo Ohtomo
H 指数:31论文数:88被引数:3,315