Mark P. Jedrychowski - Publications, H-index & Citations

Mark P. Jedrychowski

University of Central Florida

65H指数

210论文数

3.4W被引数

收录论文 70

发表时间

Irisin reduces amyloid-D by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling Irisin通过诱导ERK-STAT3信号下调后星形胶质细胞释放中性溶酶来减少淀粉样蛋白D

NEURON

IF15

2023-11-01

OAAI

Kim, Eunhee; Kim, Hyeonwoo; Jedrychowski, Mark P.; Bakiasi, Grisilda; Park, Joseph; Kruskop, Jane; Choi, Younjung; Kwak, Sang Su; Quinti, Luisa; Kim, Doo Yeon; Wrann, Christiane D.; Spiegelman, Bruce M.; Tanzi, Rudolph E.; Choi, Se Hoon

mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

CELL REPORTS

IF6.9

2023-08-01

OAAI

Shin, Sejeong; Han, Min-Joon; Jedrychowski, Mark P.; Zhang, Ziyang; Shokal, Kevan M.; Plas, David R.; Dephoure, Noah; Yoon, Sang-Oh

The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-06-26

OAAI

Moller, Lisbeth L. V.; Ali, Mona S.; Davey, Jonathan; Raun, Steffen H.; Andersen, Nicoline R.; Long, Jonathan Z.; Qian, Hongwei; Jeppesen, Jacob F.; Henriquez- Olguin, Carlos; Frank, Emma; Jensen, Thomas E.; Hojlund, Kurt; Wojtaszewski, Jorgen F. P.; Nielsen, Joachim; Chiu, Tim T.; Jedrychowski, Mark P.; Gregorevic, Paul; Klip, Amira; Richter, Erik A.; Sylow, Lykke

Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas

NATURE COMMUNICATIONS

IF15.7

2023-06-05

OAAI

Liang, Jiaxin; Yu, Deyang; Luo, Chi; Bennett, Christopher; Jedrychowski, Mark; Gygi, Steve P.; Widlund, Hans R.; Puigserver, Pere

Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90a Irisin通过其整合素受体在涉及细胞外Hsp90a的两步过程中发挥作用

MOLECULAR CELL

IF16.6

2023-06-01

OAAI

Mu, A.; Wales, Thomas E.; Zhou, Haixia; Draga-Coleta, Sorin-Valeriu; Gorgulla, Christoph; Blackmore, Katherine A.; Mittenbuhler, Melanie J.; Kim, Caroline R.; Bogoslavski, Dina; Zhang, Qiuyang; Wang, Zi-Fu; Jedrychowski, Mark P.; Seo, Hyuk-Soo; Song, Kijun; Xu, Andrew Z.; Sebastian, Luke; Gygi, Steven P.; Arthanari, Haribabu; Dhe-Paganon, Sirano; Griffin, Patrick R.; Engen, John R.; Spiegelman, Bruce M.

Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-02-01

OAAI

Williams, Niamh C.; Ryan, Dylan G.; Costa, Ana S. H.; Mills, Evanna L.; Jedrychowski, Mark P.; Cloonan, Suzanne M.; Frezza, Christian; O'Neill, Luke A.

Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2022-01-13

OAAI

You, Yang; Muraoka, Satoshi; Jedrychowski, Mark P.; Hu, Jianqiao; McQuade, Amanda K.; Young-Pearse, Tracy; Aslebagh, Roshanak; Shaffer, Scott A.; Gygi, Steven P.; Blurton-Jones, Mathew; Poon, Wayne W.; Ikezu, Tsuneya

Exercise hormone irisin is a critical regulator of cognitive function (vol 3, pg 1058, 2021)

NATURE METABOLISM

IF20.8

2021-10-07

OAAI

Islam, Mohammad R.; Valaris, Sophia; Young, Michael F.; Haley, Erin B.; Luo, Renhao; Bond, Sabrina F.; Mazuera, Sofia; Kitchen, Robert R.; Caldarone, Barbara J.; Bettio, Luis E. B.; Christie, Brian R.; Schmider, Angela B.; Soberman, Roy J.; Besnard, Antoine; Jedrychowski, Mark P.; Kim, Hyeonwoo; Tu, Hua; Kim, Eunhee; Choi, Se Hoon; Tanzi, Rudolph E.; Spiegelman, Bruce M.; Wrann, Christiane D.

Exercise hormone irisin is a critical regulator of cognitive function 运动激素irisin是认知功能的关键调节剂

NATURE METABOLISM

IF20.8

2021-08-20

177

OAAI

UCP1 governs liver extracellular succinate and inflammatory pathogenesis

NATURE METABOLISM

IF20.8

2021-05-17

103

OAAI

Mills, Evanna L.; Harmon, Cathal; Jedrychowski, Mark P.; Xiao, Haopeng; Garrity, Ryan; Tran, Nhien V.; Bradshaw, Gary A.; Fu, Accalia; Szpyt, John; Reddy, Anita; Prendeville, Hannah; Danial, Nika N.; Gygi, Steven P.; Lynch, Lydia; Chouchani, Edward T.

IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-04-01

OAAI

Yan, Shuai; Kumari, Manju; Xiao, Haopeng; Jacobs, Christopher; Kochumon, Shihab; Jedrychowski, Mark; Chouchani, Edward; Ahmad, Rasheed; Rosen, Evan D.

Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly

NATURE CHEMICAL BIOLOGY

IF13.7

2021-03-15

OAAI

Bennett, Christopher F.; O'Malley, Katherine E.; Perry, Elizabeth A.; Balsa, Eduardo; Latorre-Muro, Pedro; Riley, Christopher L.; Luo, Chi; Jedrychowski, Mark; Gygi, Steven P.; Puigserver, Pere

Enrichment of Neurodegenerative Microglia Signature in Brain-Derived Extracellular Vesicles Isolated from Alzheimer's Disease Mouse Models 从阿尔茨海默病小鼠模型分离的脑源性细胞外囊泡中神经变性小胶质细胞特征的富集

JOURNAL OF PROTEOME RESEARCH

IF3.6

2021-02-03

OAAI

Muraoka, Satoshi; Jedrychowski, Mark P.; Iwahara, Naotoshi; Abdullah, Mohammad; Onos, Kristen D.; Keezer, Kelly J.; Hu, Jianqiao; Ikezu, Seiko; Howell, Gareth R.; Gygi, Steven P.; Ikezu, Tsuneya

Tetracyclines promote survival and fitness in mitochondrial disease models 四环素类药物促进线粒体疾病模型的生存和健康

NATURE METABOLISM

IF20.8

2021-01-18

OAAI

Perry, Elizabeth A.; Bennett, Christopher F.; Luo, Chi; Balsa, Eduardo; Jedrychowski, Mark; O'Malley, Katherine E.; Latorre-Muro, Pedro; Ladley, Richard Porter; Reda, Kamar; Wright, Peter M.; Gygi, Steven P.; Myers, Andrew G.; Puigserver, Pere

Global proteomics of Ubqln2-based murine models of ALS

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Whiteley, Alexandra M.; Prado, Miguel A.; de Poot, Stefanie A. H.; Paulo, Joao A.; Ashton, Marissa; Dominguez, Sara; Weber, Martin; Hai Ngu; Szpyt, John; Jedrychowski, Mark P.; Easton, Amy; Gygi, Steven P.; Kurz, Thimo; Monteiro, Mervyn J.; Brown, Eric J.; Finley, Daniel

A Plasma Protein Network Regulates PM20D1 and N-Acyl Amino Acid Bioactivity

CELL CHEMICAL BIOLOGY

IF7.2

2020-09-01

OAAI

Kim, Joon T.; Jedrychowski, Mark P.; Wei, Wei; Fernandez, Daniel; Fischer, Curt R.; Banik, Steven M.; Spiegelman, Bruce M.; Long, Jonathan Z.

Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer's Disease Patients: A Pilot Study 阿尔茨海默病患者脑脊液中细胞外囊泡的蛋白质组学分析: 一项初步研究

CELLS

IF5.2

2020-08-25

OAAI

Muraoka, Satoshi; Jedrychowski, Mark P.; Yanamandra, Kiran; Ikezu, Seiko; Gygi, Steven P.; Ikezu, Tsuneya

The regulation of glucose and lipid homeostasis viaPLTPas a mediator ofBAT-liver communication

EMBO REPORTS

IF6.2

2020-07-16

OAAI

Sponton, Carlos H.; Hosono, Takashi; Taura, Junki; Jedrychowski, Mark P.; Yoneshiro, Takeshi; Wang, Qiang; Takahashi, Makoto; Matsui, Yumi; Ikeda, Kenji; Oguri, Yasuo; Tajima, Kazuki; Shinoda, Kosaku; Pradhan, Rachana N.; Chen, Yong; Brown, Zachary; Roberts, Lindsay S.; Ward, Carl C.; Taoka, Hiroki; Yokoyama, Yoko; Watanabe, Mitsuhiro; Karasawa, Hiroshi; Nomura, Daniel K.; Kajimura, Shingo

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death

NATURE COMMUNICATIONS

IF15.7

2020-06-01

OAAI

Balsa, Eduardo; Perry, Elizabeth A.; Bennett, Christopher F.; Jedrychowski, Mark; Gygi, Steven P.; Doench, John G.; Puigserver, Pere

Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity 兼性蛋白质硒化调节氧化还原敏感性，脂肪组织产热和肥胖

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-05-01

OAAI

Jedrychowski, Mark P.; Lu, Gina Z.; Szpyt, John; Mariotti, Marco; Garrity, Ryan; Paulo, Joao A.; Schweppe, Devin K.; Laznik-Bogoslavski, Dina; Kazak, Lawrence; Murphy, Michael P.; Gladyshev, Vadim N.; Gygi, Steven P.; Chouchani, Edward T.; Spiegelman, Bruce M.

研究方向