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C

Christina L. L. Chai

National University of Singapore

45H指数
295论文数
6.8K被引数
收录论文 89
发表时间
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Evaluating Molecular Docking Programs for RNA-Targeted Ligand Screening: Influence of Binding Modes and Ligand Types评估RNA靶向配体筛选的分子对接程序：结合模式和配体类型的影响
errJournal of Chemical Information and Modeling
IF5.3
err2026-05-12
err0
PREAI
errKaichen Wang; Louis DeFalco; Chaitanya K. Jaladanki; Roland G. Huber; Christina Li Lin Chai; Hao Fan
err分享
err收藏
Letting Go of Pains and Other Dogmas放下痛苦与其他教条
errCHEMMEDCHEM
IF3.4
err2025-09-11
err0
errOAAI
errChai, Christina L. L.
err分享
err收藏
Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/(3-catenin signaling pathwayCalcaratarin D，一种labdane型二萜类化合物，通过阻断Wnt/(3-catenin信号通路来减轻博来霉素诱导的肺纤维化。
errPHARMACOLOGICAL RESEARCH
IF10.5
err2025-06-01
err0
errOAAI
errLiao, Wupeng; Ang, Yuet; Kee, Adrian C. L.; Lim, Valencia; Lim, Albert Y. H.; Chai, Christina L. L.
err分享
err收藏
Mutagenesis-Guided Target Identification Reveals the Protein-Binding Domain of Nsp14 in Coronaviruses as the Target of a Labdane-Oxindole Compound基于诱变指导的靶点鉴定揭示了一种类二萜-恶唑烷二酮化合物在冠状病毒中Nsp14的蛋白质结合结构域为其作用靶点
errACS INFECTIOUS DISEASES
IF3.8
err2025-04-10
err0
PREAI
errHo, WS; Yogarajah, T; Mohameed, JBH; Fong, DY; Cheong, DHJ; Wong, YH; Chu, JJH; Chai, CLL
err分享
err收藏
Identification of Small-Molecule Inhibitors for Enterovirus A71 IRES by Structure-Based Virtual Screening
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-03-01
err0
PREAI
errWang, Kaichen; Lee, Sean Xian Yu; Jaladanki, Chaitanya K.; Ho, Wei Shen; Chu, Justin Jang Hann; Fan, Hao; Chai, Christina Li Lin
err分享
err收藏
Syntheses of Minutuminolate and Related Coumarin Natural Products and Evaluation of Their TNF-α Inhibitory Activities
errACS OMEGA
IF4.3
err2023-10-23
err1
errOAAI
errChoo, Malcolm Zheng Yuan; Khaw, Lachelle Wei Ting; Chai, Christina Li Lin
err分享
err收藏
Degradation of MK2 with natural compound andrographolide: A new modality for anti-inflammatory therapy
errPHARMACOLOGICAL RESEARCH
IF10.5
err2023-08-01
err4
errOAAI
errTran, Quy T. N.; Gan, Phyllis X. L.; Liao, Wupeng; Mok, Yu Keung; Chai, Christina L. L.; Wong, W. S. Fred
err分享
err收藏
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2022-12-20
err2
PREAI
errLiao, Wupeng; Foo, Hazel Yu Ci; Tran, Thi Ngoc Quy; Chai, Christina Li Lin; Wong, Wai Shiu Fred
err分享
err收藏
Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist's perspective
errDRUG DISCOVERY TODAY
IF7.5
err2022-09-01
err8
PREAI
errLee, Adrian B. C.; Tan, Meng-How; Chai, Christina L. L.
err分享
err收藏
COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?新型冠状病毒肺炎和小分子疗法的前景: 有教训吗？
errPHARMACOLOGICAL RESEARCH
IF10.5
err2022-05-01
err25
errOAAI
errHo, Wei Shen; Zhang, Ruirui; Tan, Yeong Lan; Chai, Christina Li Lin
err分享
err收藏
Promoting GAINs (Give Attention to Limitations in Assays) over PAINs Alerts: no PAINS, more GAINs
errCHEMMEDCHEM
IF3.4
err2022-02-11
err7
PREAI
errChoo, Malcolm Z. Y.; Chai, Christina L. L.
err分享
err收藏
Discovery and development of labdane-oxindole hybrids as small-molecule inhibitors against chikungunya virus infection
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-02-01
err5
PREAI
errTran, Quy Thi Ngoc; Lee, Regina Ching Hua; Liu, Hon Jin; Ran, Danli; Low, Vincent Zhan Lin; To, Dong Quang; Chu, Justin Jang Hann; Chai, Christina Li Lin
err分享
err收藏
Evaluation of 2-Bromoisobutyryl Catechol Derivatives for Atom Transfer Radical Polymerization-Functionalized Polydopamine Coatings
errLANGMUIR
IF3.9
err2021-07-16
err8
PREAI
errHsueh, Nathanael; Chai, Christina L. L.
err分享
err收藏
From irreversible to reversible covalent inhibitors: Harnessing the andrographolide scaffold for anti-inflammatory action (vol 204, 112481, 2020)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2021-01-01
err0
PREAI
errTran, Quy T. N.; Tan, Daniel W. S.; Wong, W. S. Fred; Chai, Christina L. L.
err分享
err收藏
Polypharmacology of andrographolide: beyond one molecule one target
errNATURAL PRODUCT REPORTS
IF10.6
err2021-01-01
err24
PREAI
errTran, Quy T. N.; Tan, W. S. Daniel; Wong, W. S. Fred; Chai, Christina L. L.
err分享
err收藏
Gold(I)-Catalyzed Intramolecular Hydroarylation of Phenol-Derived Propiolates and Certain Related Ethers as a Route to Selectively Functionalized Coumarins and 2H-Chromenes
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2020-11-30
err27
PREAI
errCervi, Aymeric; Vo, Yen; Chai, Christina L. L.; Banwell, Martin G.; Lan, Ping; Willis, Anthony C.
err分享
err收藏
From irreversible to reversible covalent inhibitors: Harnessing the andrographolide scaffold for anti-inflammatory action
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2020-10-01
err24
PREAI
errTran, Quy T. N.; Tan, Daniel W. S.; Wong, W. S. Fred; Chai, Christina L. L.
err分享
err收藏
Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2020-09-01
err19
errOAAI
errCheong, Eleanor Jing Yi; Nair, Pramod C.; Neo, Rebecca Wan Yi; Ho Thanh Tu; Lin, Fu; Chiong, Edmund; Esuvaranathan, Kesavan; Fan, Hao; Szmulewitz, Russell Z.; Peer, Cody J.; Figg, William D.; Chai, Christina Li Lin; Miners, John O.; Chan, Eric Chun Yong
err分享
err收藏
A fluorescence-displacement assay using molecularly imprinted polymers for the visual, rapid, and sensitive detection of the algal metabolites, geosmin and 2-methylisoborneol
errANALYTICA CHIMICA ACTA
IF6
err2019-08-01
err19
PREAI
errLi, Cheng; Mun Hong Ngai; Reddy, Karnati Konda; Leong, Sandric Chee Yew; Tong, Yen Wah; Chai, Christina Li Lin
err分享
err收藏
The identification of naturally occurring labdane diterpenoid calcaratarin D as a potential anti-inflammatory agent
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2019-07-01
err21
PREAI
errTran, Quy T. N.; Wong, W. S. Fred; Chai, Christina L. L.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
K
K. G. Neoh
H 指数: 105 · 论文数: 705
W
William D. Figg
H 指数: 101 · 论文数: 1.3K
D
David P. Fairlie
H 指数: 98 · 论文数: 716
J
Joseph F. Petrosino
H 指数: 92 · 论文数: 486
J
John O. Miners
H 指数: 80 · 论文数: 359
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