未登录Increased antibody diversification in mice vaccinated with a self-amplifying RNA versus mRNA directed against SARS-CoV-2 spike protein
Par-Young, Jennefer A.; Osmani, Lais; Doherty, Edward H.; Piecychna, Marta; Abraham, Suraj; Jain, Nikita; Thambatti, Sitalakshmi; Nazaripour, Sedigheh; Thomas, Anitha; Leng, Lin; Geall, Andrew; Kang, Insoo; Bucala, Richard .png)
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收藏Enhanced antibody class switching and T cell responses to a self-amplifying RNA vs mRNA vaccine against SARS-CoV-2 spike proteinDoherty, Edward H.; Par-Young, Jennefer; Osmani, Lais; Filler, Renata; Piecychna, Marta; Abraham, Suraj; Jain, Nikita; Thambatti, Sitalakshmi; Nazaripour, Sedigheh; Thomas, Anitha; Leng, Lin; Unutmaz, Derya; Wilen, Craig; Geall, Andrew; Kang, Insoo; Bucala, Richard 分享 收藏 Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1Tran, T.T.; Sánchez-Zuno, G.A.; Osmani, L.; Caulfield, J.; Valdez, C.N.; Piecychna, M.; Leng, L.; Armstrong, M.E.; Donnelly, S.C.; Bifulco, C.B.; et al. 通过双重抑制巨噬细胞移动抑制因子和PD-1来改善免疫治疗反应。JCI Insight 2025, 10, e191539. [Google Scholar] [CrossRef]Tran, Thuy T.; Sanchez-Zuno, Gabriela Athziri; Osmani, Lais; Caulfield, Jasmine; Valdez, Caroline Naomi; Piecychna, Marta; Leng, Lin; Armstrong, Michelle E.; Donnelly, Seamas C.; Bifulco, Carlo B.; Clister, Terri; Kulkarni, Rajan P.; Zhang, Lin; Sznol, Mario; Jilaveanu, Lucia; Kluger, Harriet M.; Kang, Insoo; Bucala, Richard 分享 收藏 分享 收藏 Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia使用别构抑制剂抑制MIF可触发急性髓系白血病中的细胞周期停滞Pantouris, G; Khurana, L; Tilstam, P; Benner, A; Cho, TY; Lelaidier, M; Perrée, M; Rosenbaum, Z; Leng, L; Foss, F; Bhandari, V; Verma, A; Bucala, R; Lolis, EJ 分享 收藏 Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemiaHuang, Yiheng; Chen, Liujun; Li, Lisha; Qi, Yadan; Tong, Haibin; Wu, Hong; Xu, Jinjie; Leng, Lin; Cheema, Sukhinder; Sun, Guang; Xia, Zhengyuan; McGuire, John; Rodrigues, Brian; Young, Lawrence H.; Bucala, Richard; Qi, Dake 分享 收藏 A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locusLi, Jia; Leng, Lin; Pantouris, Georgios; Manjula, Ramu; Piecychna, Marta; Abriola, Laura; Hu, Buqu; Lolis, Elias; Armstrong, Michelle E.; Donnelly, Seamas C.; Bucala, Richard 分享 收藏 分享 收藏 Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesityChen, Liujun; Li, Lisha; Cui, Donghong; Huang, Yiheng; Tong, Haibin; Zabihi, Haleh; Wang, Shuxia; Qi, Yadan; Lakowski, Ted; Leng, Lin; Liu, Suixin; Wu, Hong; Young, Lawrence H.; Bucala, Richard; Qi, Dake 分享 收藏 分享 收藏 A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth RegulationFingerle-Rowson, Guenter; Kaleswarapu, Dayananda Rao; Schlander, Corinna; Kabgani, Nazanin; Brocks, Tania; Reinart, Nina; Busch, Raymonde; Schuetz, Anke; Lue, Hongqi; Du, Xin; Liu, Aihua; Xiong, Huabao; Chen, Yibang; Nemajerova, Alice; Hallek, Michael; Bernhagen, Juergen; Leng, Lin; Bucala, Richard 分享 收藏 分享 收藏 MIF is a common genetic determinant of COVID-19 symptomatic infection and severityShin, J. J.; Fanr, W.; Par-Youngs, J.; Piecychna, M.; Leng, L.; Israni-Winger, K.; Qing, H.; Gu, J.; Zhao, H.; Schulz, W. L.; Unlu, S.; Kuster, J.; Young, G.; Liu, J.; Ko, A., I; Garcia, A. Baeza; Sauler, M.; Wisnewski, A., V; Young, L.; Orduna, A.; Wang, A.; Ocskay, K.; Garcia-Blesa, A.; Hegyi, P.; Armstrong, M. E.; Mitchell, P. D.; Bernardo, D.; Garami, A.; Kang, I; Bucala, R. 分享 收藏 Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV InfectionTrifone, Cesar; Baquero, Lucia; Czernikier, Alejandro; Benencio, Paula; Leng, Lin; Laufer, Natalia; Florencia Quiroga, Maria; Bucala, Richard; Ghiglione, Yanina; Turk, Gabriela 分享 收藏 分享 收藏 MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis modelTilstam, Pathricia Veronica; Schulte, Wibke; Holowka, Thomas; Kim, Bong-Sung; Nouws, Jessica; Sauler, Maor; Piecychna, Marta; Pantouris, Georgios; Lolis, Elias; Leng, Lin; Bernhagen, Juergen; Fingerle-Rowson, Guenter; Bucala, Richard 分享 收藏 Suppression of Plasmodium MIF-CD74 signaling protects against severe malariaBaeza Garcia, Alvaro; Siu, Edwin; Du, Xin; Leng, Lin; Franke-Fayard, Blandine; Janse, Chris J.; Howland, Shanshan W.; Renia, Laurent; Lolis, Elias; Bucala, Richard 分享 收藏 Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human diseaseNakamura, Akihiro; Zeng, Fanxing; Nakamura, Sayaka; Reid, Kyle T.; Gracey, Eric; Lim, Melissa; Leng, Lin; Jo, Sungsin; Park, Ye-Soo; Kusuda, Masaki; Machhar, Rohan; Boroojeni, Shaghayegh F.; Wu, Brian; Rossomacha, Evgeny; Kim, Tae-Hwan; Ciccia, Francesco; Rockel, Jason S.; Kapoor, Mohit; Inman, Robert D.; Jurisica, Igor; Crome, Sarah Q.; Bucala, Richard; Haroon, Nigil 分享 收藏 分享 收藏 分享 收藏 
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