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In vivo synergistic enhancement of MIF-mediated inflammation in acute lung injury by the plant ortholog Arabidopsis MDL1 植物直系同源拟南芥MDL1在体内协同增强MIF介导的急性肺损伤炎症 Spiller, Lukas; Zhang, Lin; Gerra, Simona; Stoppe, Christian; Scheiermann, Patrick; Calandra, Thierry; Lolis, Elias; Panstruga, Ralph; Bernhagen, Juergen; Hoffmann, Adrian 分享 收藏
A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus Li, Jia; Leng, Lin; Pantouris, Georgios; Manjula, Ramu; Piecychna, Marta; Abriola, Laura; Hu, Buqu; Lolis, Elias; Armstrong, Michelle E.; Donnelly, Seamas C.; Bucala, Richard 分享 收藏
Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose Bloom, Joshua; Pantouris, Georgios; He, Mingzhu; Aljabari, Bayan; Mishra, Lopa; Manjula, Ramu; Parkins, Andrew; Lolis, Elias J.; Al-Abed, Yousef 分享 收藏
Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells Spiller, Lukas; Manjula, Ramu; Leissing, Franz; Basquin, Jerome; Bourilhon, Priscila; Sinitski, Dzmitry; Brandhofer, Markus; Levecque, Sophie; Gerra, Simona; Sabelleck, Bjorn; Zhang, Lin; Feederle, Regina; Flatley, Andrew; Hoffmann, Adrian; Panstruga, Ralph; Bernhagen, Jurgen; Lolis, Elias 分享 收藏
Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase Chen, Emily; Widjaja, Vinnie; Kyro, Gregory; Allen, Brandon; Das, Pragnya; Prahaladan, Varsha M.; Bhandari, Vineet; Lolis, Elias J.; Batista, Victor S.; Lisi, George P. 分享 收藏
How to correct relative voxel scale factors for calculations of vector-difference Fourier maps in cryo-EM Wang, Jimin; Liu, Jinchan; Gisriel, Christopher J.; Wu, Shenping; Maschietto, Federica; Flesher, David A.; Lolis, Elias; Lisi, George P.; Brudvig, Gary W.; Xiong, Yong; Batista, Victor S. 分享 收藏
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Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors Gannam, Zira T. K.; Jamali, Haya; Kweon, Oh Sang; Herrington, James; Shillingford, Shanelle R.; Papini, Christina; Gentzel, Erik; Lolis, Elias; Bennett, Anton M.; Ellman, Jonathan A.; Anderson, Karen S. 分享 收藏
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Suppression of Plasmodium MIF-CD74 signaling protects against severe malaria Baeza Garcia, Alvaro; Siu, Edwin; Du, Xin; Leng, Lin; Franke-Fayard, Blandine; Janse, Chris J.; Howland, Shanshan W.; Renia, Laurent; Lolis, Elias; Bucala, Richard 分享 收藏
A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase Chen, Emily; Reiss, Krystle; Shah, Dilip; Manjula, Ramu; Allen, Brandon; Murphy, Eva L.; Murphy, James W.; Batista, Victor S.; Bhandari, Vineet; Lolis, Elias J.; Lisi, George P. 分享 收藏
An allosteric site on MKP5 reveals a strategy for small-molecule inhibition Gannam, Zachary T. K.; Min, Kisuk; Shillingford, Shanelle R.; Zhang, Lei; Herrington, James; Abriola, Laura; Gareiss, Peter C.; Pantouris, Georgios; Tzouvelekis, Argyrios; Kaminski, Naftali; Zhang, Xinbo; Yu, Jun; Jamali, Haya; Ellman, Jonathan A.; Lolis, Elias; Anderson, Karen S.; Bennett, Anton M. 分享 收藏
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A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity Tilstam, Pathricia Veronica; Pantouris, Georgios; Corman, Michael; Andreoli, Monica; Mahboubi, Keyvan; Davis, Gary; Du, Xin; Leng, Lin; Lolis, Elias; Bucala, Richard 分享 收藏
Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant Rosenberg, Eric M., Jr.; Harrison, Reed E. S.; Tsou, Lun Kelvin; Drucker, Natalie; Humphries, Brock; Rajasekaran, Deepa; Luker, Kathryn E.; Wu, Chien-Huang; Song, Jen-Shin; Wang, Chuan-Jen; Murphy, James W.; Cheng, Yung-Chi; Shia, Kak-Shan; Luker, Gary D.; Morikis, Dimitrios; Lolis, Elias J. 分享 收藏
Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74 Pantouris, Georgios; Ho, Junming; Shah, Dilip; Syed, Mansoor Ali; Leng, Lin; Bhandari, Vineet; Bucala, Richard; Batista, Victor S.; Loria, J. Patrick; Lolis, Elias J. 分享 收藏
Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4 Lacy, Michael; Kontos, Christos; Brandhofer, Markus; Hille, Kathleen; Groening, Sabine; Sinitski, Dzmitry; Bourilhon, Priscila; Rosenberg, Eric; Krammer, Christine; Thavayogarajah, Tharshika; Pantouris, Georgios; Bakou, Maria; Weber, Christian; Lolis, Elias; Bernhagen, Juergen; Kapurniotu, Aphrodite 分享 收藏
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