Minhang Xin

Xi'an Jiaotong University

H指数:25

被引数:2,163

个人简介

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教育背景

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Synthesis and degradation effect of PROTACs targeting EGFR triple mutants

PROTACs靶向EGFR三重突变的合成与降解效应

Bioorganic & Medicinal Chemistry

IF3

2025-10-060

PRE

Discovery of novel covalent PI3Kδ inhibitors bearing alaninamide moiety by lysine-targeted covalent strategy

通过赖氨酸靶向共价策略发现具有丙氨酸酰胺基团的 Novel covalent PI3Kδ inhibitors

European Journal of Medicinal Chemistry

IF5.9

2025-07-070

PRE

Lysine-Targeted Covalent Inhibitors of PI3Kδ Synthesis and Screening by In Situ Interaction Upgradation

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-11-190

PRE

Menin-MLL protein-protein interaction inhibitors: a patent review (2021-present)

EXPERT OPINION ON THERAPEUTIC PATENTS

IF4.6

2024-11-034

PRE

Discovery of novel pyrrolo[2,3-d]pyrimidines as potent menin-mixed lineage leukemia interaction inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-03-012

PRE

Modification of osimertinib to discover new potent EGFRC797S-TK inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-12-017

PRE

Discovery of novel pyrido[3,2-d]pyrimidine derivatives as selective and potent PI3Kδ inhibitors

发现新型吡啶并 [3，2-d] 嘧啶衍生物作为选择性和有效的PI3Kδ 抑制剂

DRUG DEVELOPMENT RESEARCH

IF4.2

2023-09-210

PRE

Design, synthesis and biological evaluation of novel selective PI3Kδ inhibitors containing pyridopyrimidine scaffold

FUTURE MEDICINAL CHEMISTRY

IF3.4

2023-08-112

PRE

Progress of small molecules for targeted protein degradation: PROTACs and other technologies

DRUG DEVELOPMENT RESEARCH

IF4.2

2023-01-0614

PRE

Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-09-296

PRE

Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors

氟喹诺酮类microRNA-21小分子抑制剂的设计、合成与评价

JOURNAL OF PHARMACEUTICAL ANALYSIS

IF8.9

2022-08-0112

OAAI

Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2022-07-012

PRE

Menin-MLL protein-protein interaction inhibitors: a patent review (2014-2021)

EXPERT OPINION ON THERAPEUTIC PATENTS

IF4.6

2022-03-1119

PRE

Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands

通过优化共价EGFR配体发现靶向EGFR突变体的有效PROTACs

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-03-0748

PRE

Recent Progress of Small Molecule Menin-MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-11-0220

PREAI

Small molecule selenium-containing compounds: Recent development and therapeutic applications

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-11-01156

PREAI

Discovery of potent small molecule PROTACs targeting mutant EGFR

靶向突变EGFR的有效小分子PROTACs的发现

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-12-0173

PREAI

Design and synthesis of novel phthalazinone derivatives as potent poly(ADP-ribose)polymerase 1 inhibitors

FUTURE MEDICINAL CHEMISTRY

IF3.4

2020-10-058

PREAI

Tomatidine protects against ischemic neuronal injury by improving lysosomal function

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2020-09-0121

PREAI

Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC)

通过蛋白水解靶向嵌合体 (PROTAC) 发现有效的表皮生长因子受体 (EGFR) 降解物

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-03-0196

PREAI

Minhang Xin

个人简介

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