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L

Laura Escudero

mcmaster university
H指数:10
被引数:853

个人简介

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教育背景

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工作经历

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荣誉奖项

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A GENOME-WIDE IN VIVO CRISPR ACTIVATION SCREEN IDENTIFIES BACE1 AS A THERAPEUTIC VULNERABILITY OF LUNG CANCER BRAIN METASTASIS

全基因组体内CRISPR激活筛选确定了BACE1为肺癌脑转移的疗法易感性靶点

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Chafe, Shawn; Zhai, Kui; Aghaei, Nikoo; Miletic, Petar; Huang, Zhi; Brown, Kevin; Mobilio, Daniel; Young, Daniel; Suk, Yujin; Grewal, Shan; Mckenna, Dillon; Alizada, Zahra; Kieliszek, Agata; Lam, Fred; Escudero, Laura; Huang, Qian; Huebner, Ariana; Lu, Jack; Ang, Patrick; Anand, Alisha; Custers, Stefan; Apel, Erika; Slassi, Sarah; Brakel, Benjamin; Kim, Jongmyung; Liu, James; Bassey-Archibong, Blessing; Abdo, Rober; Shargall, Yaron; Lu, Jian-Qiang; Cutz, Jean-Claude; Zhang, Qi; Li, Shawn; Venugopal, Chitra; Hynds, Robert; Dufour, Antoine; Moffat, Jason; Swanton, Charles; Bao, Shideng; Singh, Sheila
A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis

全基因组范围内的体内CRISPR激活筛选确定了BACE1作为肺癌脑转移的 therapeutic vulnerability。

Science Translational Medicine
IF14.6
2025-07-020
PRE
Shawn C. Chafe; Kui Zhai; Nikoo Aghaei; Petar Miletic; Zhi Huang; Kevin R. Brown; Daniel Mobilio; Daniel Young; Yujin Suk; Shan Grewal; Dillon McKenna; Zahra Alizada; Agata M. Kieliszek; Fred C. Lam; Laura Escudero; Qian Huang; Ariana Huebner; Jack Lu; Patrick Ang; Alisha Anand; Stefan Custers; Erika Apel; Sarah Slassi; Benjamin Brakel; Jongmyung Kim; James K. C. Liu; Blessing Iquo Bassey-Archibong; Rober Abdo; Yaron Shargall; Jian-Qiang Lu; Jean-Claude Cutz; Qi Zhang; Shawn Shun-Cheng Li; Chitra Venugopal; Robert E. Hynds; Antoine Dufour; Jason Moffat; Charles Swanton; Shideng Bao; Sheila K. Singh
De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases
CELL REPORTS MEDICINE
IF10.6
2024-10-010
OAAI
Kieliszek, Agata M.; Mobilio, Daniel; Bassey-Archibong, Blessing I.; Johnson, Jarrod W.; Piotrowski, Mathew L.; de Araujo, Elvin D.; Sedighi, Abootaleb; Aghaei, Nikoo; Escudero, Laura; Ang, Patrick; Gwynne, William D.; Zhang, Cunjie; Quaile, Andrew; McKenna, Dillon; Subapanditha, Minomi; Tokar, Tomas; Shaikh, Muhammad Vaseem; Zhai, Kui; Chafe, Shawn C.; Gunning, Patrick T.; Montenegro-Burke, J. Rafael; Venugopal, Chitra; Magolan, Jakob; Singh, Sheila K.
Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Gwynne, William D.; Suk, Yujin Suk; Custers, Stefan; Mikolajewicz, Nicholas; Chan, Jeremy K.; Zador, Zsolt; Chafe, Shawn C.; Zhai, Kui; Escudero, Laura; Zhang, Cunjie; Zaslaver, Olga; Chokshi, Chirayu; Shaikh, Muhammad Vaseem; Bakhshinyan, David; Burns, Ian; Chaudhry, Iqra; Nachmani, Omri; Mobilio, Daniel; Maich, William T.; Mero, Patricia; Brown, Kevin R.; Quaile, Andrew T.; Venugopal, Chitra; Moffat, Jason; Montenegro-Burke, J. Rafael; Singh, Sheila K.
Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
NATURE COMMUNICATIONS
IF15.7
2021-03-0853
OAAI
Rubio-Perez, Carlota; Planas-Rigol, Ester; Trincado, Juan L.; Bonfill-Teixidor, Ester; Arias, Alexandra; Marchese, Domenica; Moutinho, Catia; Serna, Garazi; Pedrosa, Leire; Iurlaro, Raffaella; Martinez-Ricarte, Francisco; Escudero, Laura; Cordero, Esteban; Cicuendez, Marta; Ruiz, Sara; Parra, Genis; Nuciforo, Paolo; Gonzalez, Josep; Pineda, Estela; Sahuquillo, Juan; Tabernero, Josep; Heyn, Holger; Seoane, Joan
Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
NATURE COMMUNICATIONS
IF15.7
2020-10-2781
OAAI
Escudero, Laura; Llort, Anna; Arias, Alexandra; Diaz-Navarro, Ander; Martinez-Ricarte, Francisco; Rubio-Perez, Carlota; Mayor, Regina; Caratu, Ginevra; Martinez-Saez, Elena; Vazquez-Mendez, Elida; Lesende-Rodriguez, Ivan; Hladun, Raquel; Gros, Luis; Ramon y Cajal, Santiago; Poca, Maria A.; Puente, Xose S.; Sahuquillo, Juan; Gallego, Soledad; Seoane, Joan
Cell free circulating tumor DNA in cerebrospinal fluid detects and monitors central nervous system involvement of B-cell lymphomas
HAEMATOLOGICA
IF7.9
2020-02-2092
OAAI
Bobillo, Sabela; Crespo, Marta; Escudero, Laura; Mayor, Regina; Raheja, Priyanka; Carpio, Cecilia; Rubio-Perez, Carlota; Tazon-Vega, Barbara; Palacio, Carlos; Carabia, Julia; Jimenez, Isabel; Nieto, Juan C.; Montoro, Julia; Martinez-Ricarte, Francisco; Castellvi, Josep; Simo, Marc; Puigdefabregas, Lluis; Abrisqueta, Pau; Bosch, Francesc; Seoane, Joan
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy

LIF调节肿瘤相关巨噬细胞中的CXCL9并阻止CD8 T细胞肿瘤浸润损害anti-PD1治疗

NATURE COMMUNICATIONS
IF15.7
2019-06-11161
OAAI
Pascual-Garcia, Monica; Bonfill-Teixidor, Ester; Planas-Rigol, Ester; Rubio-Perez, Carlota; Ludaro, Raffaella; Arias, Alexandra; Cuartas, Isabel; Sala-Hojman, Ada; Escudero, Laura; Martinez-Ricarte, Francisco; Huber-Ruano, Isabel; Nuciforo, Paolo; Pedrosa, Leire; Marques, Carolina; Brana, Irene; Garralda, Elena; Vieito, Maria; Squatrito, Massimo; Pineda, Estela; Graus, Francesc; EspejoH, Carmen; Sahuquillo, Juan; Tabernero, Josep; Seoane, Joan

研究方向

暂未获取到该数据
S
Sheila K. Singh
H 指数:43论文数:498被引数:2.0万
C
Chitra Venugopal
H 指数:32论文数:336被引数:3,738
Y
Yujin Suk
H 指数:10论文数:67被引数:457
S
Stefan Custers
H 指数:4论文数:36被引数:133
J
Jason Moffat
H 指数:73论文数:602被引数:3.0万
J
Joan Seoane
H 指数:62论文数:296被引数:2.2万
K
Kevin R. Brown
H 指数:37论文数:260被引数:1.0万
S
Shawn C. Chafe
H 指数:26论文数:155被引数:3,390
K
Kui Zhai
H 指数:20论文数:60被引数:1,979
F
Francisco Martínez‐Ricarte
H 指数:23论文数:69被引数:3,976