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Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malaria Marques-da-Silva, Camila; Schmidt-Silva, Clyde; Bowers, Carson; Appiah, Nana; Charles-Chess, Essel; Shiau, Justine C.; Park, Eui-Soon; Yuan, Zhongyu; Kim, Bae-Hoon; Kyle, Dennis E.; Harty, John T.; Macmicking, John D.; Kurup, Samarchith P. 分享 收藏
A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites 药物重定位方法揭示了恶性疟原虫休眠子中可靶向的表观遗传通路 Maher, Steven P.; Bakowski, Malina A.; Vantaux, Amelie; Flannery, Erika L.; Andolina, Chiara; Gupta, Mohit; Antonova-Koch, Yevgeniya; Argomaniz, Magdalena; Cabrera-Mora, Monica; Campo, Brice; Chao, Alexander T.; Chatterjee, Arnab K.; Cheng, Wayne T.; Chuenchob, Vorada; Cooper, Caitlin A.; Cottier, Karissa; Galinski, Mary R.; Harupa-Chung, Anke; Ji, Hana; Joseph, Sean B.; Lenz, Todd; Lonardi, Stefano; Matheson, Jessica; Mikolajczak, Sebastian A.; Moeller, Timothy; Orban, Agnes; Padin-Irizarry, Vivian; Pan, Kastin; Peneau, Julie; Prudhomme, Jacques; Roesch, Camille; Ruberto, Anthony; Sabnis, Saniya S.; Saney, Celia L.; Sattabongkot, Jetsumon; Sereshki, Saleh; Suriyakan, Sangrawee; Ubalee, Ratawan; Wang, Yinsheng; Wasisakun, Praphan; Yin, Jiekai; Popovici, Jean; McNamara, Case W.; Joyner, Chester; Nosten, Francois H.; Witkowski, Benoit; Le Roch, Karine G.; Kyle, Dennis E. 分享 收藏
Discovery and optimization of a novel carboxamide scaffold with selective antimalarial activity 新型羧酰胺骨架的发现及其选择性抗疟活性的优化 Wagner, Alicia; Trombley, Roger; Podgurski, Maris; Ruberto, Anthony A.; Cui, Meng; Cooper, Caitlin A.; Long, William E.; Nguyen, Gia-Bao; Marin, Adriana A.; Mai, Sarah Lee; Lombardo, Franco; Maher, Steven P.; Kyle, Dennis E.; Manetsch, Roman 分享 收藏
Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria I型干扰素诱导肝细胞中的鸟苷酸结合蛋白和溶酶体防御以控制疟疾 Marques-da-Silva, Camila; Schmidt-Silva, Clyde; Bowers, Carson; Charles-Chess, Nana Appiah Essel; Samuel, Cristina; Shiau, Justine C.; Park, Eui-Soon; Yuan, Zhongyu; Kim, Bae-Hoon; Kyle, Dennis E.; Harty, John T.; MacMicking, John D.; Kurup, Samarchith P. 分享 收藏
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Extended blood stage sensitivity profiles of Plasmodium cynomolgi to doxycycline and tafenoquine, as a model for Plasmodium vivax 作为间日疟原虫模型，食蟹猴疟原虫对强力霉素和tafenoquine的血液阶段敏感性曲线扩展 Christensen, Peter; Cinzah, Rosy; Suwanarusk, Rossarin; Chua, Adeline Chiew Yen; Kaneko, Osamu; Kyle, Dennis E.; Aung, Htin Lin; Matheson, Jessica; Bifani, Pablo; Renia, Laurent; Cook, Gregory M.; Snounou, Georges; Russell, Bruce 分享 收藏
In Vitro Antimalarial Activity of Trichothecenes against Liver and Blood Stages of Plasmodium Species Parvatkar, Prakash T.; Maher, Steven P.; Zhao, Yingzhao; Cooper, Caitlin A.; de Castro, Sagan T.; Peneau, Julie; Vantaux, Amelie; Witkowski, Benoit; Kyle, Dennis E.; Manetsch, Roman 分享 收藏
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Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes (vol 14, 1149145, 2023) Ferrins, Lori; Buskes, Melissa J.; Kapteyn, Madison M.; Engels, Hannah N.; Enos, Suzanne E.; Lu, Chenyang; Klug, Dana M.; Singh, Baljinder; Quotadamo, Antonio; Bachovchin, Kelly; Tear, Westley F.; Spaulding, Andrew E.; Forbes, Katherine C.; Bag, Seema; Rivers, Mitch; Leblanc, Catherine; Burchfield, Erin; Armand, Jeremy R.; Diaz-Gonzalez, Rosario; Ceballos-Perez, Gloria; Garcia-Hernandez, Raquel; Perez-Moreno, Guiomar; Bosch-Navarrete, Cristina; Gomez-Linan, Claudia; Ruiz-Perez, Luis Miguel; Gamarro, Francisco; Gonzalez-Pacanowska, Dolores; Navarro, Miguel; Mensa-Wilmot, Kojo; Pollastri, Michael P.; Kyle, Dennis E.; Rice, Christopher A. 分享 收藏
Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases Kassu, Mintesinot; Parvatkar, Prakash T.; Milanes, Jillian; Monaghan, Neil P.; Kim, Chungsik; Dowgiallo, Matthew; Zhao, Yingzhao; Asakawa, Ami H.; Huang, Lili; Wagner, Alicia; Miller, Brandon; Carter, Karissa; Barrett, Kayleigh F.; Tillery, Logan M.; Barrett, Lynn K.; Phan, Isabelle Q.; Subramanian, Sandhya; Myler, Peter J.; Van Voorhis, Wesley C.; Leahy, James W.; Rice, Christopher A.; Kyle, Dennis E.; Morris, James; Manetsch, Roman 分享 收藏
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AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes Marques-da-Silva, Camila; Poudel, Barun; Baptista, Rodrigo P.; Peissig, Kristen; Hancox, Lisa S.; Shiau, Justine C.; Pewe, Lecia L.; Shears, Melanie J.; Kanneganti, Thirumala-Devi; Sinnis, Photini; Kyle, Dennis E.; Gurung, Prajwal; Harty, John T.; Kurup, Samarchith P. 分享 收藏
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Cryopreservation of Plasmodium Sporozoites Bowers, Carson; Hancox, Lisa; Peissig, Kristen; Shiau, Justine C. C.; Vantaux, Amelie; Witkowski, Benoit; Phal, Sivchheng; Maher, Steven P. P.; Harty, John T. T.; Kyle, Dennis E. E.; Kurup, Samarchith P. P. 分享 收藏
Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine Ward, Kurt E.; Christensen, Peter; Racklyeft, Annie; Dhingra, Satish K.; Chua, Adeline C. Y.; Remmert, Caroline; Suwanarusk, Rossarin; Matheson, Jessica; Blackman, Michael J.; Kaneko, Osamu; Kyle, Dennis E.; Lee, Marcus C. S.; Moon, Robert W.; Snounou, Georges; Renia, Laurent; Fidock, David A.; Russell, Bruce; Bifani, Pablo 分享 收藏
Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp. Botnar, Alona; Lawrence, Grant; Maher, Steven P.; Vantaux, Amelie; Witkowski, Benoit; Shiau, Justine C.; Merino, Emilio F.; De Vore, David; Yang, Christian; Murray, Cameron; Cassera, Maria B.; Leahy, James W.; Kyle, Dennis E. 分享 收藏
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Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144) Cank, Kristof B.; Shepherd, Robert A.; Knowles, Sonja L.; Rangel-Grimaldo, Manuel; Raja, Huzefa A.; Bunch, Zoie L.; Cech, Nadja B.; Rice, Christopher A.; Kyle, Dennis E.; Falkinham, Joseph O., III; Burdette, Joanna E.; Oberlies, Nicholas H. 分享 收藏
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