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In vivo screen of Plasmodium targets for mosquito-based malaria control 基于蚊媒疟疾控制的疟原虫体内靶点筛选 Probst, Alexandra S.; Paton, Douglas G.; Appetecchia, Federico; Bopp, Selina; Adams, Kelsey L.; Rinvee, Tasneem A.; Pou, Sovitj; Winter, Rolf; Du, Esrah W.; Yahiya, Sabrina; Vidoudez, Charles; Singh, Naresh; Rodrigues, Janneth; Castaneda-Casado, Pablo; Tammaro, Chiara; Chen, Daisy; Godinez-Macias, Karla P.; Jaramillo, Jasmine L.; Poce, Giovanna; Rubal, Michael J.; Nilsen, Aaron; Winzeler, Elizabeth A.; Baum, Jake; Burrows, Jeremy N.; Riscoe, Michael K.; Wirth, Dyann F.; Catteruccia, Flaminia 分享 收藏
Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4 N-乙酰胺基吲哚类化合物的优化与表征：靶向PfATP4的抗疟疾药物研究 Awalt, Jon Kyle; Ooi, Zi Kang; Ashton, Trent D.; Mansouri, Mahta; Calic, Petar P. S.; Zhou, Qingmiao; Vasanthan, Santhya; Lee, Serena; Loi, Katie; Jarman, Kate E.; Penington, Jocelyn S.; Qiu, Deyun; Zhang, Xinxin; Lehane, Adele M.; Mao, Emma Y.; Gancheva, Maria R.; Wilson, Danny W.; Giannangelo, Carlo; MacRaild, Christopher A.; Creek, Darren J.; Yeo, Tomas; Sheth, Tanaya; Fidock, David A.; Churchyard, Alisje; Baum, Jake; Famodimu, Mufuliat T.; Delves, Michael J.; Kristan, Mojca; Stewart, Lindsay; Sutherland, Colin J.; Coyle, Rachael; Jagoe, Hannah; Lee, Marcus C. S.; Chowdury, Mrittika; de Koning-Ward, Tania F.; Baud, Delphine; Brand, Stephen; Jackson, Paul F.; Cowman, Alan F.; Dans, Madeline G.; Sleebs, Brad E. 分享 收藏
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b 针对线粒体蛋白，细胞色素b的环丙基甲酰胺的抗疟活性的探索和表征 Awalt, Jon Kyle; Su, Wenyin; Nguyen, William; Loi, Katie; Jarman, Kate E.; Penington, Jocelyn S.; Ramesh, Saishyam; Fairhurst, Kate J.; Yeo, Tomas; Park, Heekuk; Uhlemann, Anne-Catrin; Maity, Bikash Chandra; De, Nirupam; Mukherjee, Partha; Chakraborty, Arnish; Churchyard, Alisje; Famodimu, Mufuliat T.; Delves, Michael J.; Baum, Jake; Mittal, Nimisha; Winzeler, Elizabeth A.; Papenfuss, Anthony T.; Chowdury, Mrittika; de Koning-Ward, Tania F.; Maier, Alexander G.; van Dooren, Giel G.; Baud, Delphine; Brand, Stephen; Fidock, David A.; Jackson, Paul F.; Cowman, Alan F.; Dans, Madeline G.; Sleebs, Brad E. 分享 收藏
Tambjamines as Fast-Acting Multistage Antimalarials Kumar, Amrendra; Li, Yuexin; Dodean, Rozalia A.; Roth, Alison; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Lee, Patricia J.; Pybus, Brandon S.; Martin, Monica; Pannone, Kristina; Dinh, Hieu T.; Blount, Cameron; Chetree, Ravi; Deluca, Jesse; Evans, Martin; Nadeau, Robert; Vuong, Chau; Leed, Susan; Black, Chad; Sousa, Jason; Nolan, Christina; Ceja, Frida G.; Rasmussen, Stephanie A.; Tumwebaze, Patrick K.; Rosenthal, Philip J.; Cooper, Roland A.; Rottmann, Matthias; Orjuela-Sanchez, Pamela; Meister, Stephan; Winzeler, Elizabeth A.; Delves, Michael J.; Matthews, Holly; Baum, Jake; Kirby, Robert W.; Burrows, Jeremy N.; Duffy, James; Peyton, David H.; Reynolds, Kevin A.; Kelly, Jane X.; Kancharla, Papireddy 分享 收藏
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture Andradi-Brown, Clare; Wichers-Misterek, Jan Stephan; von Thien, Heidrun; Hoeppner, Yannick D.; Scholz, Judith A. M.; Hansson, Helle; Hocke, Emma Filtenborg; Gilberger, Tim Wolf; Duffy, Michael F.; Lavstsen, Thomas; Baum, Jake; Otto, Thomas D.; Cunnington, Aubrey J.; Bachmann, Anna 分享 收藏
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Sensitive Detection of Asymptomatic and Symptomatic Malaria with Seven Novel Parasite-Specific LAMP Assays and Translation for Use at Point-of-Care Malpartida-Cardenas, Kenny; Moser, Nicolas; Ansah, Felix; Pennisi, Ivana; Ahu Prah, Diana; Amoah, Linda Eva; Awandare, Gordon; Hafalla, Julius Clemence R.; Cunnington, Aubrey; Baum, Jake; Rodriguez-Manzano, Jesus; Georgiou, Pantelis 分享 收藏
Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design Moussaoui, Dihia; Robblee, James P.; Robert-Paganin, Julien; Auguin, Daniel; Fisher, Fabio; Fagnant, Patricia M.; Macfarlane, Jill E.; Schaletzky, Julia; Wehri, Eddie; Mueller-Dieckmann, Christoph; Baum, Jake; Trybus, Kathleen M.; Houdusse, Anne 分享 收藏
Radial spoke protein 9 is necessary for axoneme assembly in Plasmodium but not in trypanosomatid parasites Ramakrishnan, Chandra; Fort, Ceecile; Marques, Sara Rute; Ferguson, David J. P.; Gransagne, Marion; Baum, Jake; Chaouch, Soraya; Mouray, Elisabeth; Kohl, Linda; Wheeler, Richard J.; Sinden, Robert E. 分享 收藏
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7-N-Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc1 Complex 具有有效抗疟活性的7-n取代的3-恶二唑喹诺酮类药物靶向细胞色素bc1复合物 Nguyen, William; Dans, Madeline G.; Currie, Iain; Awalt, Jon Kyle; Bailey, Brodie L.; Lumb, Chris; Ngo, Anna; Favuzza, Paola; Palandri, Josephine; Ramesh, Saishyam; Penington, Jocelyn; Jarman, Kate E.; Mukherjee, Partha; Chakraborty, Arnish; Maier, Alexander G.; van Dooren, Giel G.; Papenfuss, Tony; Wittlin, Sergio; Churchyard, Alisje; Baum, Jake; Winzeler, Elizabeth A.; Baud, Delphine; Brand, Stephen; Jackson, Paul F.; Cowman, Alan F.; Sleebs, Brad E. 分享 收藏
Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4 靶向PfATP4的2，3-二氢喹唑啉酮-3-甲酰胺类抗疟药的优化 Ashton, Trent D.; Dans, Madeline G.; Favuzza, Paola; Ngo, Anna; Lehane, Adele M.; Zhang, Xinxin; Qiu, Deyun; Maity, Bikash Chandra; De, Nirupam; Schindler, Kyra A.; Yeo, Tomas; Park, Heekuk; Uhlemann, Anne-Catrin; Churchyard, Alisje; Baum, Jake; Fidock, David A.; Jarman, Kate E.; Lowes, Kym N.; Baud, Delphine; Brand, Stephen; Jackson, Paul F.; Cowman, Alan F.; Sleebs, Brad E. 分享 收藏
Fast-Killing Tyrosine Amide ((S)-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus (Pf CARL) Imlay, Leah S.; Lawong, Aloysus K.; Gahalawat, Suraksha; Kumar, Ashwani; Xing, Chao; Mittal, Nimisha; Wittlin, Sergio; Churchyard, Alisje; Niederstrasser, Hanspeter; Crespo-Fernandez, Benigno; Posner, Bruce A.; Gamo, Francisco-Javier; Baum, Jake; Winzeler, Elizabeth A.; Laleu, Benoit; Ready, Joseph M.; Phillips, Margaret A. 分享 收藏
A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein Yahiya, Sabrina; Saunders, Charlie N.; Hassan, Sarah; Straschil, Ursula; Fischer, Oliver J.; Rueda-Zubiaurre, Ainoa; Haase, Silvia; Vizcay-Barrena, Gema; Famodimu, Mufuliat Toyin; Jordan, Sarah; Delves, Michael J.; Tate, Edward W.; Barnard, Anna; Fuchter, Matthew J.; Baum, Jake 分享 收藏
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High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria Tamaki, Fabio; Fisher, Fabio; Milne, Rachel; Teran, Fernando Sanchez-Roman; Wiedemar, Natalie; Wrobel, Karolina; Edwards, Darren; Baumann, Hella; Gilbert, Ian H.; Baragana, Beatriz; Baum, Jake; Wyllie, Susan 分享 收藏
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