未登录 Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements Chardon, Florence M.; McDiarmid, Troy A.; Page, Nicholas F.; Daza, Riza M.; Martin, Beth K.; Domcke, Silvia; Regalado, Samuel G.; Lalanne, Jean-Benoit; Calderon, Diego; Li, Xiaoyi; Starita, Lea M.; Sanders, Stephan J.; Ahituv, Nadav; Shendure, Jay 分享 收藏
Single-cell analysis of chromatin and expression reveals age- and sex-associated alterations in the human heart Read, David F.; Booth, Gregory T.; Daza, Riza M.; Jackson, Dana L.; Gladden, Rula Green; Srivatsan, Sanjay R.; Ewing, Brent; Franks, Jennifer M.; Spurrell, Cailyn H.; Gomes, Anne Roshella; O'Day, Diana; Gogate, Aishwarya A.; Martin, Beth K.; Larson, Haleigh; Pfleger, Christian; Starita, Lea; Lin, Yiing; Shendure, Jay; Lin, Shin; Trapnell, Cole 分享 收藏
Retinoic acid induces human gastruloids with posterior embryo-like structures 视黄酸诱导具有后胚样结构的人胃泌素 Hamazaki, Nobuhiko; Yang, Wei; Kubo, Connor A.; Qiu, Chengxiang; Martin, Beth K.; Garge, Riddhiman K.; Regalado, Samuel G.; Nichols, Eva K.; Pendyala, Sriram; Bradley, Nicholas; Fowler, Douglas M.; Lee, Choli; Daza, Riza M.; Srivatsan, Sanjay; Shendure, Jay 分享 收藏
Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters Lalanne, Jean-Benoit; Regalado, Samuel G.; Domcke, Silvia; Calderon, Diego; Martin, Beth K.; Li, Xiaoyi; Li, Tony; Suiter, Chase C.; Lee, Choli; Trapnell, Cole; Shendure, Jay 分享 收藏
Predicting cellular responses to complex perturbations in high-throughput screens 在高通量筛选中预测细胞对复杂扰动的反应 Lotfollahi, Mohammad; Susmelj, Anna Klimovskaia; De Donno, Carlo; Hetzel, Leon; Ji, Yuge; Ibarra, Ignacio L.; Srivatsan, Sanjay R.; Naghipourfar, Mohsen; Daza, Riza M.; Martin, Beth; Shendure, Jay; McFaline-Figueroa, Jose L.; Boyeau, Pierre; Wolf, F. Alexander; Yakubova, Nafissa; Guennemann, Stephan; Trapnell, Cole; Lopez-Paz, David; Theis, Fabian J. 分享 收藏
Machine learning dissection of human accelerated regions in primate neurodevelopment 灵长类动物神经发育中人类加速区域的机器学习解剖 Whalen, Sean; Inoue, Fumitaka; Ryu, Hane; Fair, Tyler; Markenscoff-Papadimitriou, Eirene; Keough, Kathleen; Kircher, Martin; Martin, Beth; Alvarado, Beatriz; Elor, Orry; Cintron, Dianne Laboy; Williams, Alex; Samee, Abul Hassan; Thomas, Sean; Krencik, Robert; Ullian, Erik M.; Kriegstein, Arnold; Rubenstein, John L.; Shendure, Jay; Pollen, Alex A.; Ahituv, Nadav; Pollard, Katherine S. 分享 收藏
Optimized single-nucleus transcriptional profiling by combinatorial indexing Martin, Beth K.; Qiu, Chengxiang; Nichols, Eva; Phung, Melissa; Green-Gladden, Rula; Srivatsan, Sanjay; Blecher-Gonen, Ronnie; Beliveau, Brian J.; Trapnell, Cole; Cao, Junyue; Shendure, Jay 分享 收藏
Results of genetic analysis of 11 341 participants enrolled in the My Life, Our Future hemophilia genotyping initiative in the United States 参加 “我的生活，我们的未来血友病基因分型计划” 的11名341参与者的遗传分析结果 Johnsen, Jill M.; Fletcher, Shelley N.; Dove, Angela; McCracken, Haley; Martin, Beth K.; Kircher, Martin; Josephson, Neil C.; Shendure, Jay; Ruuska, Sarah E.; Valentino, Leonard A.; Pierce, Glenn F.; Watson, Crystal; Cheng, Dunlei; Recht, Michael; Konkle, Barbara A. 分享 收藏
Systematic reconstruction of cellular trajectories across mouse embryogenesis 小鼠胚胎发生过程中细胞轨迹的系统重建 Qiu, Chengxiang; Cao, Junyue; Martin, Beth K.; Li, Tony; Welsh, Ian C.; Srivatsan, Sanjay; Huang, Xingfan; Calderon, Diego; Noble, William Stafford; Disteche, Christine M.; Murray, Stephen A.; Spielmann, Malte; Moens, Cecilia B.; Trapnell, Cole; Shendure, Jay 分享 收藏
Precise genomic deletions using paired prime editing 使用配对prime编辑进行精确的基因组缺失 Choi, Junhong; Chen, Wei; Suiter, Chase C.; Lee, Choli; Chardon, Florence M.; Yang, Wei; Leith, Anh; Daza, Riza M.; Martin, Beth; Shendure, Jay 分享 收藏
SwabExpress: An End-to-End Protocol for Extraction-Free COVID-19 Testing SwabExpress: 一种用于无萃取新型冠状病毒肺炎测试的端到端协议 Srivatsan, Sanjay; Heidl, Sarah; Pfau, Brian; Martin, Beth K.; Han, Peter D.; Zhong, Weizhi; van Raay, Katrina; McDermot, Evan; Opsahl, Jordan; Gamboa, Luis; Smith, Nahum; Truong, Melissa; Cho, Shari; Barrow, Kaitlyn A.; Rich, Lucille M.; Stone, Jeremy; Wolf, Caitlin R.; McCulloch, Denise J.; Kim, Ashley E.; Brandstetter, Elisabeth; Sohlberg, Sarah L.; Ilcisin, Misja; Geyer, Rachel E.; Chen, Wei; Gehring, Jase; Kosuri, Sriram; Bedford, Trevor; Rieder, Mark J.; Nickerson, Deborah A.; Chu, Helen Y.; Konnick, Eric Q.; Debley, Jason S.; Shendure, Jay; Lockwood, Christina M.; Starita, Lea M. 分享 收藏
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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements (vol 15, 2387, 2020) Gordon, M. Grace; Inoue, Fumitaka; Martin, Beth; Schubach, Max; Agarwal, Vikram; Whalen, Sean; Feng, Shiyun; Zhao, Jingjing; Ashuach, Tal; Ziffra, Ryan; Kreimer, Anat; Georgakopoulos-Soares, Ilias; Yosef, Nir; Ye, Chun Jimmie; Pollard, Katherine S.; Shendure, Jay; Kircher, Martin; Ahituv, Nadav 分享 收藏
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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements lentiMPRA和MPRAflow用于基因调控元件的高通量功能表征 Gordon, M. Grace; Inoue, Fumitaka; Martin, Beth; Schubach, Max; Agarwal, Vikram; Whalen, Sean; Feng, Shiyun; Zhao, Jingjing; Ashuach, Tal; Ziffra, Ryan; Kreimer, Anat; Georgakopoulous-Soares, Ilias; Yosef, Nir; Ye, Chun Jimmie; Pollard, Katherine S.; Shendure, Jay; Kircher, Martin; Ahituv, Nadav 分享 收藏
Integration of multiple epigenomic marks improves prediction of variant impact in saturation mutagenesis reporter assay Shigaki, Dustin; Adato, Orit; Adhikari, Aashish N.; Dong, Shengcheng; Hawkins-Hooker, Alex; Inoue, Fumitaka; Juven-Gershon, Tamar; Kenlay, Henry; Martin, Beth; Patra, Ayoti; Penzar, Dmitry D.; Schubach, Max; Xiong, Chenling; Yan, Zhongxia; Boyle, Alan P.; Kreimer, Anat; Kulakoyskiy, Ivan, V; Reid, John; Unger, Ron; Yosef, Nir; Shendure, Jay; Ahituv, Nadav; Kirche, Martin; Beer, Michael A. 分享 收藏
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Multiplex assessment of protein variant abundance by massively parallel sequencing 通过大规模平行测序对蛋白质变体丰度进行多重评估 Matreyek, Kenneth A.; Starita, Lea M.; Stephany, Jason J.; Martin, Beth; Chiasson, Melissa A.; Gray, Vanessa E.; Kircher, Martin; Khechaduri, Arineh; Dines, Jennifer N.; Hause, Ronald J.; Bhatia, Smita; Evans, William E.; Relling, Mary V.; Yang, Wenjian; Shendure, Jay; Fowler, Douglas M. 分享 收藏
Novel approach to genetic analysis and results in 3000 hemophilia patients enrolled in the My Life, Our Future initiative 基因分析的新方法和结果在3000血友病患者参加我的生活，我们的未来倡议 Johnsen, Jill M.; Fletcher, Shelley N.; Huston, Haley; Roberge, Sarah; Martin, Beth K.; Kircher, Martin; Josephson, Neil C.; Shendure, Jay; Ruuska, Sarah; Koerper, Marion A.; Morales, Jaime; Pierce, Glenn F.; Aschman, Diane J.; Konkle, Barbara A. 分享 收藏
BRCA Testing by Single-Molecule Molecular Inversion Probes Neveling, Kornelia; Mensenkamp, Arjen R.; Derks, Ronny; Kwint, Michael; Ouchene, Hicham; Steehouwer, Marloes; van Lier, Bart; Bosgoed, Ermanno; Rikken, Alwin; Tychon, Marloes; Zafeiropoulou, Dimitra; Castelein, Steven; Hehir-Kwa, Jayne; Thung, Djie Tjwan; Hofste, Tom; Lelieveld, Stefan H.; Bertens, Stijn M. M.; Adan, Ivo B. J. F.; Eijkelenboom, Astrid; Tops, Bastiaan B.; Yntema, Helger; Stokowy, Tomasz; Knappskog, Per M.; Hoberg-Vetti, Hildegunn; Steen, Vidar M.; Boyle, Evan; Martin, Beth; Ligtenberg, Marjolijn J. L.; Shendure, Jay; Nelen, Marcel R.; Hoischen, Alexander 分享 收藏
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