Thomas Langmann - Publications, H-index & Citations

Thomas Langmann

University of Cologne

64H指数

290论文数

1.8W被引数

收录论文 115

发表时间

The role of human complement factor H in retinal immune response and the prospects for targeted therapy for age-related macular degeneration (AMD)人补体因子H在视网膜免疫反应中的作用及针对年龄相关性黄斑变性（AMD）的靶向治疗前景

Expert Opinion on Therapeutic Targets

IF4.4

2026-05-21

OAAI

Anne Wolf; Thomas Clahsen; Thomas Langmann

Severe Joubert syndrome in family with homozygous POC1B p.Arg106Pro variant is due to a co-inherited deep-intronic mutation in the neighboring CEP290 gene

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2025-07-01

OAAI

Betz, Christian; Reusch, Bjoern; Langmann, Thomas; Habbig, Sandra; Beck, Bodo B.; Bolz, Hanno J.

Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration 苔藓来源的人补体因子H调节视网膜免疫反应并减轻视网膜变性

JOURNAL OF NEUROINFLAMMATION

IF10.1

2025-04-11

OAAI

Hector, Mandy; Behnke, Verena; Dabrowska-Schlepp, Paulina; Busch, Andreas; Schaaf, Andreas; Langmann, Thomas; Wolf, Anne

Inhibition of DYRK1B BY C81 impedes inflammatory processes in leukocytes by reducing STAT3 activity

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2025-02-22

OAAI

Ciurus, Sarah; Elewa, Mohammed A. F.; Palmer, Megan A.; Wolf, Anne; Hector, Mandy; Fuhrmann, Dominik C.; Thomas, Dominique; Gurke, Robert; Schwalm, Martin P.; Berger, Lena; Zech, Thomas J.; Burgers, Luisa D.; Marschalek, Rolf; Geisslinger, Gerd; Knapp, Stefan; Langmann, Thomas; Bracher, Franz; Weigert, Andreas; Fuerst, Robert

Kinetic changes in microglia-related retinal transcripts in experimental autoimmune uveoretinitis (EAU) of B10.RIII mice B10.RIII小鼠实验性自身免疫性葡萄膜视网膜炎(EAU)中与小胶质细胞相关的视网膜转录物的动力学变化

JOURNAL OF NEUROINFLAMMATION

IF10.1

2025-02-10

OAAI

Kasper, Maren; Karlstetter, Marcus; Wildschuetz, Lena; Scholz, Rebecca; Busch, Martin; Bauer, Dirk; zu Hoerste, Gerd Meyer; Thanos, Solon; Langmann, Thomas; Heiligenhaus, Arnd

C3aR1-Deletion Delays Retinal Degeneration in a White-Light Damage Mouse Model

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2025-01-07

OAAI

Behnke, Verena; Wolf, Anne; Hector, Mandy; Langmann, Thomas

Decreased sialylation elicits complement-related microglia response and bipolar cell loss in the mouse retina

GLIA

IF5.1

2024-09-03

OAAI

Cuevas-Rios, German; Abou Assale, Tawfik; Wissfeld, Jannis; Bungartz, Annemarie; Hofmann, Julia; Langmann, Thomas; Neumann, Harald

Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases

PROGRESS IN RETINAL AND EYE RESEARCH

IF14.7

2024-05-01

OAAI

Hector, Mandy; Langmann, Thomas; Wolf, Anne

2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinases

ANGIOGENESIS

IF9.2

2024-02-26

OAAI

Zech, T. J.; Wolf, A.; Hector, M.; Bischoff-Kont, I.; Krishnathas, G. M.; Kuntschar, S.; Schmid, T.; Bracher, F.; Langmann, T.; Fuerst, R.

Reactive microglia as triggers and effectors of inflammasome activation in the retina

ACTA OPHTHALMOLOGICA

IF2.8

2024-01-18

OAAI

Langmann, Thomas

Microglia depletion/repopulation does not affect light-induced retinal degeneration in mice

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-01-15

OAAI

Laudenberg, Nils; Kinuthia, Urbanus Muthai; Langmann, Thomas

CEP162 deficiency causes human retinal degeneration and reveals a dual role in ciliogenesis and neurogenesis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-04-17

OAAI

Nuzhat, Nafisa; Van Schil, Kristof; Liakopoulos, Sandra; Bauwens, Miriam; Rey, Alfredo Duenas; Kaeseberg, Stephan; Jaeger, Melanie; Willer, Jason R.; Winter, Jennifer; Truong, Hanh M.; Gruartmoner, Nuria; Van Heetvelde, Mattias; Wolf, Joachim; Merget, Robert; Grasshoff-Derr, Sabine; Van Dorpe, Jo; Hoorens, Anne; Stoehr, Heidi; Mansard, Luke; Roux, Anne-Francoise; Langmann, Thomas; Dannhausen, Katharina; Rosenkranz, David; Wissing, Karl M.; Van Lint, Michel; Rossmann, Heidi; Haeuser, Friederike; Nuernberg, Peter; Thiele, Holger; Zechner, Ulrich; Pearring, Jillian N.; De Baere, Elfride; Bolz, Hanno J.

Immunomodulation for retinal degenerations

ACTA OPHTHALMOLOGICA

IF2.8

2022-12-20

OAAI

Langmann, Thomas

Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration

JOURNAL OF NEUROINFLAMMATION

IF10.1

2022-09-17

OAAI

Tabel, Mona; Wolf, Anne; Szczepan, Manon; Xu, Heping; Jaegle, Herbert; Moehle, Christoph; Chen, Mei; Langmann, Thomas

MotiQ: an open-source toolbox to quantify the cell motility and morphology of microglia

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2022-09-15

OAAI

Hansen, Jan N.; Brueckner, Matthias; Pietrowski, Marie J.; Jikeli, Jan F.; Plescher, Monika; Beckert, Hannes; Schnaars, Mareike; Fuelle, Lorenz; Reitmeier, Katharina; Langmann, Thomas; Foerster, Irmgard; Boche, Delphine; Petzold, Gabor C.; Halle, Annett

Cytokine signaling as key regulator of pathological angiogenesis in the eye

EBIOMEDICINE

IF10.8

2021-11-01

OAAI

Langmann, Thomas

VEGFR1 signaling in retinal angiogenesis and microinflammation VEGFR1信号在视网膜血管生成和微炎症中的作用

PROGRESS IN RETINAL AND EYE RESEARCH

IF14.7

2021-09-01

179

OAAI

Uemura, Akiyoshi; Fruttiger, Marcus; D'Amore, Patricia A.; De Falco, Sandro; Joussen, Antonia M.; Sennlaub, Florian; Brunck, Lynne R.; Johnson, Kristian T.; Lambrou, George N.; Rittenhouse, Kay D.; Langmann, Thomas

Microglia and Inflammatory Responses in Diabetic Retinopathy

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-11-06

187

OAAI

Kinuthia, Urbanus Muthai; Wolf, Anne; Langmann, Thomas

Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration

JOURNAL OF NEUROINFLAMMATION

IF10.1

2020-11-03

OAAI

Khan, Amir Saeed; Langmann, Thomas

A mega-analysis of expression quantitative trait loci in retinal tissue 视网膜组织中表达数量性状位点的mega分析

PLOS GENETICS

IF3.7

2020-09-01

OAAI

Strunz, Tobias; Kiel, Christina; Grassmann, Felix; Ratnapriya, Rinki; Kwicklis, Madeline; Karlstetter, Marcus; Fauser, Sascha; Arend, Nicole; Swaroop, Anand; Langmann, Thomas; Wolf, Armin; Weber, Bernhard H. F.

研究方向