Bridget K. Wagner - Publications, H-index & Citations

Bridget K. Wagner

Broad Institute of MIT and Harvard

45H指数

174论文数

1.1W被引数

收录论文 79

发表时间

Small molecule splicing modulators that disrupt O-GlcNAc homeostasis 小分子剪接调节剂可破坏O-GlcNAc稳态

Nature Communications

IF15.7

2026-01-12

OAAI

Steven S. Cheng; Alison C. Mody; Amedeo Vetere; Ashwin Govindan; Yewon Lee; Danielle E. Khost; Rohan Narayan; Timothy B. Sackton; Nicholas K. Conrad; Bridget K. Wagner; Christina M. Woo

KD025 Is a Casein Kinase 2 Inhibitor That Protects Against Glucolipotoxicity in β-Cells

DIABETES

IF7.5

2024-01-11

OAAI

Devkota, Ranjan; Small, Jonnell C.; Carbone, Kaycee; Glass, Michael A.; Vetere, Amedeo; Wagner, Bridget K.

Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

ELIFE

IF0

2023-09-21

OAAI

Kahraman, Sevim; Shibue, Kimitaka; De Jesus, Dario F.; Kim, Hyunki; Hu, Jiang; Manna, Debasish; Wagner, Bridget; Choudhary, Amit; Kulkarni, Rohit N.

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

CELL METABOLISM

IF30.9

2023-07-01

OAAI

Basile, Giorgio; Vetere, Amedeo; Hu, Jiang; Ijaduola, Oluwaseun; Zhang, Yi; Liu, Ka-Cheuk; Eltony, Amira M.; De Jesus, Dario F.; Fukuda, Kazuki; Doherty, Grace; Leech, Colin A.; Chepurny, Oleg G.; Holz, George G.; Yun, Seok-Hyun; Andersson, Olov; Choudhary, Amit; Wagner, Bridget K.; Kulkarni, Rohit N.

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity FALCON系统地询问游离脂肪酸生物学并鉴定出一种新的脂毒性介质

CELL METABOLISM

IF30.9

2023-05-01

OAAI

Wieder, Nicolas; Fried, Juliana Coraor; Kim, Choah; Sidhom, Eriene-Heidi; Brown, Matthew R.; Marshall, Jamie L.; Arevalo, Carlos; Dvela-Levitt, Moran; Kost-Alimova, Maria; Sieber, Jonas; Gabriel, Katlyn R.; Pacheco, Julian; Clish, Clary; Abbasi, Hamdah Shafqat; Singh, Shantanu; Rutter, Justine C.; Therrien, Martine; Yoon, Haejin; Lai, Zon Weng; Baublis, Aaron; Subramanian, Renuka; Devkota, Ranjan; Small, Jonnell; Sreekanth, Vedagopuram; Han, Myeonghoon; Lim, Donghyun; Carpenter, Anne E.; Flannick, Jason; Finucane, Hilary; Haigis, Marcia C.; Claussnitzer, Melina; Sheu, Eric; Stevens, Beth; Wagner, Bridget K.; Choudhary, Amit; Shaw, Jillian L.; Pablo, Juan Lorenzo; Greka, Anna

Predicting compound activity from phenotypic profiles and chemical structures

NATURE COMMUNICATIONS

IF15.7

2023-04-08

OAAI

Moshkov, Nikita; Becker, Tim; Yang, Kevin; Horvath, Peter; Dancik, Vlado; Wagner, Bridget K.; Clemons, Paul A.; Singh, Shantanu; Carpenter, Anne E.; Caicedo, Juan C.

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

NATURE COMMUNICATIONS

IF15.7

2023-03-13

OAAI

Dahlin, Jayme L.; Hua, Bruce K.; Zucconi, Beth E.; Nelson, Shawn D.; Singh, Shantanu; Carpenter, Anne E.; Shrimp, Jonathan H.; Lima-Fernandes, Evelyne; Wawer, Mathias J.; Chung, Lawrence P. W.; Agrawal, Ayushi; O'Reilly, Mary; Barsyte-Lovejoy, Dalia; Szewczyk, Magdalena; Li, Fengling; Lak, Parnian; Cuellar, Matthew; Cole, Philip A.; Meier, Jordan L.; Thomas, Tim; Baell, Jonathan B.; Brown, Peter J.; Walters, Michael A.; Clemons, Paul A.; Schreiber, Stuart L.; Wagner, Bridget K.

Identifying type 2 diabetes risk genes by β-cell CRISPR screening

NATURE GENETICS

IF31.8

2023-01-13

PREAI

Wagner, Bridget K.

A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules

NATURE CELL BIOLOGY

IF19.1

2022-11-17

OAAI

Lim, Donghyun; Zhou, Qingxuan; Cox, Kurt J.; Law, Benjamin K.; Lee, Miseon; Kokkonda, Praveen; Sreekanth, Vedagopuram; Pergu, Rajaiah; Chaudhary, Santosh K.; Gangopadhyay, Soumyashree A.; Maji, Basudeb; Lai, Sophia; Amako, Yuka; Thompson, David B.; Subramanian, Hari K. K.; Mesleh, Michael F.; Dandik, Vlado; Clemons, Paul A.; Wagner, Bridget K.; Woo, Christina M.; Church, George M.; Choudhary, Amit

SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

CELL REPORTS

IF6.9

2022-08-01

OAAI

Casteels, Tamara; Bajew, Simon; Reinis, Jiri; Enders, Lennart; Schuster, Michael; Fontaine, Frederic; Mueller, Andre C.; Wagner, Bridget K.; Bock, Christoph; Kubicek, Stefan

Small-molecule discovery in the pancreatic beta cell

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2022-06-01

OAAI

Wagner, Bridget K.

Emerging diabetes therapies: Bringing back the ?-cells

MOLECULAR METABOLISM

IF6.6

2022-06-01

OAAI

Basile, G.; Qadir, M. M. F.; Mauvais-Jarvis, F.; Vetere, A.; Shoba, V; Modell, A. E.; Pastori, R. L.; Russ, H. A.; Wagner, B. K.; Dominguez-Bendala, J.

Chemical strategies to understand and manipulate host-pathogen interactions

CELL CHEMICAL BIOLOGY

IF7.2

2022-05-01

OAAI

Wagner, Bridget K.; Dey, Mishtu

Phenotypic Screening for Small Molecules that Protect ?-Cells from Glucolipotoxicity

ACS CHEMICAL BIOLOGY

IF3.8

2022-04-19

OAAI

Small, Jonnell C.; Joblin-Mills, Aidan; Carbone, Kaycee; Kost-Alimova, Maria; Ayukawa, Kumiko; Khodier, Carol; Dancik, Vlado; Clemons, Paul A.; Munkacsi, Andrew B.; Wagner, Bridget K.

Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis-Interstitial Lung Disease Open-Label Extension of a Phase 3 Randomized Controlled Trial

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2022-03-15

OAAI

Khanna, Dinesh; Lin, Celia J. F.; Furst, Daniel E.; Wagner, Bridget; Zucchetto, Mauro; Raghu, Ganesh; Martinez, Fernando J.; Goldin, Jonathan; Siegel, Jeffrey; Denton, Christopher P.

From type 1 diabetes biology to therapy: The Human Islet Research Network

MOLECULAR METABOLISM

IF6.6

2021-12-01

OAAI

Kaddis, John S.; Rouse, Layla; V. Parent, Audrey; Saunders, Diane C.; Shalev, Anath; Stabler, Cherie L.; Stoffers, Doris A.; Wagner, Bridget K.; Niland, Joyce C.

Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension

SCIENCE ADVANCES

IF12.5

2021-10-22

OAAI

Negi, Vinny; Yang, Jimin; Speyer, Gil; Pulgarin, Andres; Handen, Adam; Zhao, Jingsi; Tai, Yi Yin; Tang, Ying; Culley, Miranda K.; Yu, Qiujun; Forsythe, Patricia; Gorelova, Anastasia; Watson, Annie M.; Al Aaraj, Yassmin; Satoh, Taijyu; Sharifi-Sanjani, Maryam; Rajaratnam, Arun; Sembrat, John; Provencher, Steeve; Yin, Xianglin; Vargas, Sara O.; Rojas, Mauricio; Bonnet, Sebastien; Torrino, Stephanie; Wagner, Bridget K.; Schreiber, Stuart L.; Dai, Mingji; Bertero, Thomas; Al Ghouleh, Imad; Kim, Seungchan; Chan, Stephen Y.

Phenotypic approaches to small-molecule discovery in chemical biology

CELL CHEMICAL BIOLOGY

IF7.2

2021-03-01

OAAI

Wagner, Bridget K.; Dey, Mishtu

Nuisance compounds in cellular assays

CELL CHEMICAL BIOLOGY

IF7.2

2021-03-01

OAAI

Dahlin, Jayme L.; Auld, Douglas S.; Rothenaigner, Ina; Haney, Steve; Sexton, Jonathan Z.; Nissink, J. Willem M.; Walsh, Jarrod; Lee, Jonathan A.; Strelow, John M.; Willard, Francis S.; Ferrins, Lori; Baell, Jonathan B.; Walters, Michael A.; Hua, Bruce K.; Hadian, Kamyar; Wagner, Bridget K.

Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells

LIFE SCIENCE ALLIANCE

IF2.9

2021-01-29

OAAI

Kahraman, Sevim; Manna, Debasish; Dirice, Ercument; Maji, Basudeb; Small, Jonnell; Wagner, Bridget K.; Choudhary, Amit; Kulkarni, Rohit N.

研究方向