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H

Heidi M. Ferguson

merck & company
H指数:14
被引数:721

个人简介

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荣誉奖项

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STimulator of INterferon Genes Agonism Accelerates Antitumor Activity in Poorly Immunogenic Tumors
MOLECULAR CANCER THERAPEUTICS
IF5.5
2022-02-088
OA
Perera, Samanthi A.; Kopinja, Johnny E.; Ma, Yanhong; Muise, Eric S.; Laskey, Jason; Chakravarthy, Kalyan; Chen, Yiping; Cui, Long; Presland, Jeremy; Sathe, Manjiri; Javaid, Sarah; Minnihan, Ellen C.; Ferguson, Heidi M.; Piesvaux, Jennifer; Pan, Bo-Sheng; Zhao, Shuxia; Sharma, Sharad K.; Woo, Hyun Chong; Pucci, Vincenzo; Knemeyer, Ian; Cemerski, Saso; Cumming, Jared; Trotter, B. Wesley; Tse, Archie; Khilnani, Anuradha; Ranganath, Sheila; Long, Brian J.; Bennett, David Jonathan; Addona, George H.
Sonoporation-Enhanced Delivery of STING Agonist Induced Robust Immune Modulation and Tumor Regression

声穿孔增强STING激动剂的递送诱导强大的免疫调节和肿瘤消退

ADVANCED THERAPEUTICS
IF2.6
2021-08-245
OAAI
Xu, Jun; Solban, Nicolas; Wang, Yun; Ferguson, Heidi; Perera, Samanthi; Lin, Ken; Cai, Mingmei; Paul, Miller; Schutt, Ernest G.; Larsen, Clayton T.; Li, Rhodemann; Saklatvala, Robert; Long, Brian J.; Ranganath, Sheila; Procopio, Adam T.; Mittal, Sachin; Templeton, Allen C.
Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells
ONCOIMMUNOLOGY
IF6.3
2021-03-1840
OAAI
Wang, Yun; Cui, Long; Georgiev, Peter; Singh, Latika; Zheng, Yanyan; Yu, Ying; Grein, Jeff; Zhang, Chunsheng; Muise, Eric S.; Sloman, David L.; Ferguson, Heidi; Yu, Hongshi; Pierre, Cristina St.; Dakle, Pranal J.; Pucci, Vincenzo; Baker, James; Loboda, Andrey; Linn, Doug; Brynczka, Christopher; Wilson, Doug; Haines, Brian B.; Long, Brian; Wnek, Richard; Sadekova, Svetlana; Rosenzweig, Michael; Haidle, Andrew; Han, Yongxin; Ranganath, Sheila H.
Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-02-2617
OA
Li, Derun; Deng, Yongqi; Achab, Abdelghani; Bharathan, Indu; Hopkins, Brett Andrew; Yu, Wensheng; Zhang, Hongjun; Sanyal, Sulagna; Pu, Qinglin; Zhou, Hua; Liu, Kun; Lim, Jongwon; Fradera, Xavier; Lesburg, Charles A.; Lammens, Alfred; Martinot, Theodore A.; Cohen, Ryan D.; Doty, Amy C.; Ferguson, Heidi; Nickbarg, Elliott B.; Cheng, Mangeng; Spacciapoli, Peter; Geda, Prasanthi; Song, Xuelei; Smotrov, Nadya; Abeywickrema, Pravien; Andrews, Christine; Chamberlin, Chad; Mabrouk, Omar; Curran, Patrick; Richards, Matthew; Saradjian, Peter; Miller, J. Richard; Knemeyer, Ian; Otte, Karin M.; Vincent, Stella; Sciammetta, Nunzio; Pasternak, Alexander; Bennett, David Jonathan; Han, Yongxin
Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors

发现有效且可口服的双环 [1.1.1] 戊烷衍生的Indoleamine-2，3-双加氧酶1 (IDO1) 抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2020-07-1557
OAAI
Pu, Qinglin; Zhang, Hongjun; Guo, Liangqin; Cheng, Mangeng; Doty, Amy C.; Ferguson, Heidi; Fradera, Xavier; Lesburg, Charles A.; McGowan, Meredeth A.; Miller, J. Richard; Geda, Prasanthi; Song, Xuelei; Otte, Karin; Sciammetta, Nunzio; Solban, Nicolas; Yu, Wensheng; Sloman, David L.; Zhou, Hua; Lammens, Alfred; Neumann, Lars; Bennett, David Jonathan; Pasternak, Alexander; Han, Yongxin
Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2020-01-0920
OAAI
Zhang, Hongjun; Lapointe, Blair T.; Anthony, Neville; Azevedo, Rita; Cals, Jos; Correll, Craig C.; Daniels, Matthew; Deshmukh, Sujal; van Eenenaam, Hans; Ferguson, Heidi; Hegde, Laxminarayan G.; Karstens, Willem Jan; Maclean, John; Miller, J. Richard; Moy, Lily Y.; Simov, Vladimir; Nagpal, Sunil; Oubrie, Arthur; Palte, Rachel L.; Parthasarathy, Gopal; Sciammetta, Nunzio; van der Stelt, Mario; Woodhouse, Janice D.; Trotter, B. Wesley; Barr, Kenneth
Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy

发现用于癌症免疫疗法的氨基-环丁基芳烃衍生的Indoleamine-2，3-双加氧酶1 (IDO1) 抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-09-1838
OAAI
Zhang, Hongjun; Liu, Kun; Pu, Qinglin; Achab, Abdelghani; Ardolino, Michael J.; Cheng, Mangeng; Deng, Yongqi; Doty, Amy C.; Ferguson, Heidi; Fradera, Xavier; Knemeyer, Ian; Kurukulasuriya, Ravi; Lam, Yu-hong; Lesburg, Charles A.; Martinot, Theodore A.; McGowan, Meredeth A.; Miller, J. Richard; Otte, Karin; Biju, Purakattle J.; Sciammetta, Nunzio; Solban, Nicolas; Yu, Wensheng; Zhou, Hua; Wang, Xiao; Bennett, David Jonathan; Han, Yongxin
Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity

抑制ror γ T使tcr α 基因重排偏斜并限制T细胞库多样性

CELL REPORTS
IF6.9
2016-12-0153
OAAI
Guo, Yanxia; MacIsaac, Kenzie D.; Chen, Yi; Miller, Richard J.; Jain, Renu; Joyce-Shaikh, Barbara; Ferguson, Heidi; Wang, I-Ming; Cristescu, Razvan; Mudgett, John; Engstrom, Laura; Piers, Kyle J.; Baltus, Gretchen A.; Barr, Kenneth; Zhang, Hongjun; Mehmet, Huseyin; Hegde, Laxminarayan G.; Hu, Xiao; Carter, Laura L.; Aicher, Thomas D.; Glick, Gary; Zaller, Dennis; Hawwari, Abbas; Correll, Craig C.; Jones, Dallas C.; Cua, Daniel J.

研究方向

暂未获取到该数据
H
Hongjun Zhang
H 指数:16论文数:29被引数:737
N
Nunzio Sciammetta
H 指数:15论文数:32被引数:755
D
David Jonathan Bennett
H 指数:25论文数:82被引数:2,572
Y
Yongxin Han
H 指数:36论文数:171被引数:4,467
J
J. Richard Miller
H 指数:32论文数:95被引数:5,293
F
Francis C. Szoka
H 指数:79论文数:243被引数:2.7万
J
Jean M. J. Fréchet
H 指数:170论文数:925被引数:10.5万
A
Amy C. Doty
H 指数:10论文数:19被引数:559
X
Xavier Fradera
H 指数:28论文数:99被引数:3,832
W
Wensheng Yu
H 指数:23论文数:72被引数:1,909