Gene Cutler

cnrs - national institute for biology (insb)

H指数:16

被引数:1,480

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Adf-1 is a nonmodular transcription factor that contains a TAF-binding Myb-like motif

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2747

OAAI

Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-09-206

PRE

Jackson, Jeffrey J.; Shibuya, Grant M.; Ravishankar, Buvana; Adusumilli, Lavanya; Bradford, Delia; Brockstedt, Dirk G.; Bucher, Cyril; Bui, Minna; Cho, Cynthia; Colas, Christoph; Cutler, Gene; Dukes, Adrian; Han, Xinping; Hu, Dennis X.; Jacobson, Scott; Kassner, Paul D.; Katibah, George E.; Ko, Michelle Yoo Min; Kolhatkar, Urvi; Leger, Paul R.; Ma, Anqi; Marshall, Lisa; Maung, Jack; Ng, Andrew A.; Okano, Akinori; Pookot, Deepa; Poon, Daniel; Ramana, Chandru; Reilly, Maureen K.; Robles, Omar; Schwarz, Jacob B.; Shakhmin, Anton A.; Shunatona, Hunter P.; Sreenivasan, Raashi; Tivitmahaisoon, Parcharee; Xu, Mengshu; Zaw, Thant; Wustrow, David J.; Zibinsky, Mikhail

EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22

PLOS PATHOGENS

IF4.9

2022-01-1317

OAAI

Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo

MOLECULAR CANCER THERAPEUTICS

IF5.5

2020-10-0223

OAAI

Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-07-1519

PREAI

Discovery of potent and selective inhibitors of USP7 with anti-tumor activity in vitro and in vivo

CANCER RESEARCH

IF16.6

2019-07-011

PRE

Targeting the stress response kinase GCN2 to restore immunity in the tumor microenvironment

CANCER RESEARCH

IF16.6

2019-07-010

Ravishankar, Buvana; Adusumilli, Lavanya; Pookot, Deepa Pookot; Huang, Emily; Sreenivasan, Raashi; Marshall, Lisa; Kaveri, Deepika; Talay, Oezcan; Suthram, Silpa; Miakicheva, Svetlana; Okal, Abood; Zibinsky, Mikhail; Jackson, Jeffrey; Shibuya, Grant; Leger, Paul; Tivitmahaisoon, Parcharee; Jacobson, Scott; Wong, Steve; Wadsworth, Angela; Sanchez, Jerick; Brovarney, Martin; Chian, David; Marubayashi, Sachie; Jorapur, Aparna; Bradford, Delia; Colas, Christophe; Cutler, Gene; Schwartz, Jacob; Wustrow, David; Kassner, Paul; Brockstedt, Dirk

Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-06-1721

PREAI

Discovery and optimization of potent and selective inhibitors of USP7 to enhance anti-tumor immunity and target tumor growth

CANCER RESEARCH

IF16.6

2018-07-010

PRE

Abraham, Betty; Adusumilli, Lavanya; Biannic, Berenger; Bradford, Delia; Brovarney, Martin; Chian, David; Cutler, Gene; Han, Xinping; Hu, Dennis; Jacobson, Scott; Johnson, Sherra; Kassner, Paul; Kaveri, Deepika; Ketcham, John; Kim, Andrea; Leger, Paul; Marshall, Lisa; Marubayashi, Sachie; Maung, Jack; McKinnell, Jenny; Meleza, Cesar; Ohol, Yamini; Okano, Akinori; Peiser, Leanne; Pookot, Deepa; Rana, Payal; Schwarz, Jacob; Shah, Nick; Shibuya, Grant; Sun, Michael; Suthram, Silpa; Talay, Oezcan; Wadsworth, Angela; Wustrow, David; Young, Kyle; Napper, Andrew

EBV associated tumors have increased regulatory T cell recruitment and are therefore a potential indication for treatment with potent and selective small molecule CCR4 antagonists

CANCER RESEARCH

IF16.6

2018-07-010

PRE

The roles of IL-18 and IL-18r in experimental autoimmune encephalomyelitis are complex and not easily revealed by knockout studies

CYTOKINE

IF3.7

2010-10-010

PREAI

Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways

BIOCHEMICAL JOURNAL