John S. Schneekloth - Publications, H-index & Citations

John S. Schneekloth

National Cancer Institute

33H指数

141论文数

4.0K被引数

收录论文 66

发表时间

Chemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structures, revealing ligand-dependent transcriptional perturbation 化学修饰的CRISPR-Cas9能够靶向单个G-四链体和i-基序结构，揭示了配体依赖的转录扰动。

Nature Communications

IF15.7

2025-12-09

OAAI

Sabrina Pia Nuccio; Enrico Cadoni; Roxani Nikoloudaki; Silvia Galli; An-Jie Ler; Claudia Sanchez-Cabanillas; Thomas E. Maher; Ella Fan; Dilek Guneri; Gem Flint; Minghui Zhu; Ling Sum Liu; Christopher R. Fullenkamp; Zoë Waller; Luca Magnani; John S. Schneekloth; Marco Di Antonio

Expanding the crosslinking mass spectrometry toolbox with vinyl sulfone crosslinkers 通过乙烯砜类交联剂扩展交联质谱工具箱

Molecular & Cellular Proteomics

IF5.5

2025-10-21

OAAI

Anthony Ciancone; Haitao Wu; Katerina Atallah-Yunes; Kitaik Lee; Chris Sibley; Jesse Spivey; Rolf E. Swenson; John S. Schneekloth; Francis J. O’Reilly

Discovery of Thiacyanine Dyes as a New Class of Potent Coronavirus Inhibitors that Suppress Viral RNA Synthesis 硫代菁染料作为一类新的强效冠状病毒抑制剂，可抑制病毒RNA合成

Journal of Biological Chemistry

IF3.9

2025-08-05

OAAI

Tianyi Zhang; Valerie Altouma; Joshua A. Sommers; Adaira J. Dumm; Debbie Kennedy; Hongjie Xia; Mo Yang; Christopher R. Fullenkamp; Shar-yin N. Huang; Yutong Xue; Shuaikun Su; Weiping Shen; Caitlin E. Haren; Tomasz Kulikowicz; Yves Pommier; John S. Schneekloth; Mariano A. Garcia-Blanco; Robert M. Brosh; Weidong Wang

Machine Learning-Augmented Molecular Dynamics Simulations (MD) Reveal Insights Into the Disconnect Between Affinity and Activation of ZTP Riboswitch Ligands 机器学习增强的分子动力学模拟（MD）揭示了ZTP核酶开关配体在亲和力与活化之间的脱耦机制。

Angewandte Chemie International Edition

IF0

2025-06-22

OAAI

Christopher R. Fullenkamp; Shams Mehdi; Christopher P. Jones; Logan Tenney; Patricio Pichling; Peri R. Prestwood; Adrian R. Ferré-D'Amaré; Pratyush Tiwary; John S. Schneekloth

Harnessing Molecular Recognition for Small-Molecule-Mediated Reversible Photochemical Control Over mRNA Translation 利用分子识别实现小分子介导的可逆光化学控制mRNA翻译

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2025-04-22

PREAI

Parmar, Shaifaly; Tenney, Logan; Liang, Xiao; Routzahn, John T.; Sibley, Christopher D.; Schneekloth Jr, John S.

Use of a small molecule microarray screen to identify inhibitors of the catalytic RNA subunit of Methanobrevibacter smithii RNase P

NUCLEIC ACIDS RESEARCH

IF13.1

2024-12-16

OAAI

Sidharthan, Vaishnavi; Sibley, Christopher D.; Dunne-Dombrink, Kara; Yang, Mo; Zahurancik, Walter J.; Balaratnam, Sumirtha; Wilburn, Damien B.; Schneekloth, John S.; Gopalan, Venkat

Inferring phase transitions and critical exponents from limited observations with thermodynamic maps

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-12-16

OAAI

Herron, Lukas; Mondal, Kinjal; Schneekloth, John S.; Tiwary, Pratyush

Bioorthogonal Cyclopropenones for Investigating RNA Structure

ACS CHEMICAL BIOLOGY

IF3.8

2024-12-06

OAAI

Chen, Sharon; Sibley, Christopher D.; Latifi, Brandon; Balaratnam, Sumirtha; Dorn, Robert S.; Luptak, Andrej; Schneekloth, John S.; Prescher, Jennifer A.

Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics

CELL CHEMICAL BIOLOGY

IF7.2

2024-12-01

PREAI

Temme, J. Sebastian; Tan, Zibin; Li, Mi; Yang, Mo; Wlodawer, Alexander; Huang, Xuefei; Schneekloth, John S.; Gildersleeve, Jeffrey C.

Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression

NATURE COMMUNICATIONS

IF15.7

2024-09-17

OAAI

Parmar, Shaifaly; Bume, Desta Doro; Connelly, Colleen M.; Boer, Robert E.; Prestwood, Peri R.; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth Jr, John S.

Competitive Microarray Screening Reveals Functional Ligands for the DHX15 RNA G-Quadruplex 竞争性微阵列筛选揭示了DHX15 RNA G-四链体的功能配体

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-05-02

OAAI

Prestwood, Peri R.; Yang, Mo; Lewis, Grace V.; Balaratnam, Sumirtha; Yazdani, Kamyar; Schneekloth Jr, John S.

A polymorphic TERT tandem repeat creating an expandable intronic G4 quadruplex is associated with TERT expression, relative leukocyte telomere length and cancer risk 产生可扩展内含子G4四链体的多态性TERT串联重复序列与TERT表达，相对白细胞端粒长度和癌症风险相关

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Florez-Vargas, Oscar; Ho, Michelle; Hogshead, Max; Lee, Chia-Han; Forsythe, Kaitlin; Papenberg, Brenen; Jones, Kristine; Luo, Wen; Teshome, Kedest; Blauwendraat, Cornelis; Kolmogorov, Mikhail; Chanock, Stephen J.; Machiela, Mitchell J.; Schneekloth, John; Gadalla, Shahinaz; Savage, Sharon A.; Mbulaiteye, Sam M.; Prokunina-Olsson, Ludmila

KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma

NATURE COMMUNICATIONS

IF15.7

2024-02-24

OAAI

Kim, Yong Yean; Gryder, Berkley E.; Sinniah, Ranuka; Peach, Megan L.; Shern, Jack F.; Abdelmaksoud, Abdalla; Pomella, Silvia; Woldemichael, Girma M.; Stanton, Benjamin Z.; Milewski, David; Barchi Jr, Joseph J.; Schneekloth Jr, John S.; Chari, Raj; Kowalczyk, Joshua T.; Shenoy, Shilpa R.; Evans, Jason R.; Song, Young K.; Wang, Chaoyu; Wen, Xinyu; Chou, Hsien-Chao; Gangalapudi, Vineela; Esposito, Dominic; Jones, Jane; Procter, Lauren; O'Neill, Maura; Jenkins, Lisa M.; Tarasova, Nadya I.; Wei, Jun S.; McMahon, James B.; O'Keefe, Barry R.; Hawley, Robert G.; Khan, Javed

Decoding complexity in biomolecular recognition of DNA i-motifs with microarrays

NUCLEIC ACIDS RESEARCH

IF13.1

2023-11-14

OAAI

Yazdani, Kamyar; Seshadri, Srinath; Tillo, Desiree; Yang, Mo; Sibley, Christopher D.; Vinson, Charles; Schneekloth, John S.

RNA as an off-target for FDA-approved drugs

NATURE CHEMISTRY

IF20.2

2023-09-11

PREAI

Fullenkamp, Christopher R.; Schneekloth, John S.

Investigating the NRAS 5′ UTR as a target for small molecules

CELL CHEMICAL BIOLOGY

IF7.2

2023-06-01

OAAI

Balaratnam, Sumirtha; Torrey, Zachary R.; Calabrese, David R.; Banco, Michael T.; Yazdani, Kamyar; Liang, Xiao; Fullenkamp, Christopher R.; Seshadri, Srinath; Holewinski, Ronald J.; Andresson, Thorkell; Ferre-D'Amare, Adrian R.; Incarnato, Danny; Schneekloth, John S., Jr.

Discovery of Small Molecules Targeting the Frameshifting Element RNA in SARS-CoV-2 Viral Genome SARS-CoV-2病毒基因组中靶向移码元件RNA的小分子的发现

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2023-05-11

PREAI

Yang, Mo; Olatunji, Feyisola P.; Rhodes, Curran; Balaratnam, Sumirtha; Dunne-Dombrink, Kara; Seshadri, Srinath; Liang, Xiao; Jones, Christopher P.; Le Grice, Stuart F. J.; Ferre-D'Amare, Adrian R.; Schneekloth, Jr John S.

Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules 使用小分子靶向RNA降解的邻近诱导核酸降解剂 (PINAD) 方法

ACS CENTRAL SCIENCE

IF10.4

2023-04-26

OAAI

Mikutis, Sigitas; Rebelo, Maria; Yankova, Eliza; Gu, Muxin; Tang, Cong; Coelho, Ana R.; Yang, Mo; Hazemi, Madoka E.; de Miranda, Marta Pires; Eleftheriou, Maria; Robertson, Max; Vassiliou, George S.; Adams, David J.; Simas, J. Pedro; Corzana, Francisco; Schneekloth Jr, John S.; Tzelepis, Konstantinos; Bernardes, Goncalo J. L.

Crystal Structure of an i-Motif from the HRAS Oncogene Promoter 来自HRAS癌基因启动子的i基序的晶体结构

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-04-25

OAAI

Li, Kevin S.; Jordan, Deondre; Lin, Linda Y.; McCarthy, Sawyer E.; Schneekloth Jr, John S.; Yatsunyk, Liliya A.

Custom G4 DNA microarray can determine large-scale binding selectivity of small molecules and proteins to oncogene G-quadruplexes

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Wu, Guanhui; Chen, Luying; Huseman, Kristen; Tillo, Desiree; Ray, Sreejana; Chang, Ta-Chau; Schneekloth, John S.; Vinson, Charles; Yang, Danzhou

研究方向