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K

Károly Tóth

centre national de la recherche scientifique (cnrs)

46H指数
321论文数
6.5K被引数
收录论文 70
发表时间
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LAVR-289, a broad-spectrum antiviral, protects immunosuppressed Syrian hamsters against lethal adenovirus challengeLAVR-289，一种广谱抗病毒药物，可保护免疫抑制的叙利亚仓鼠免受致死性腺病毒攻击。
errAntiviral Research
IF4
err2025-06-26
err0
PREAI
errAnn E. Tollefson; Anna Cline-Smith; Vincent Roy; Luigi A. Agrofoglio; Getahun Abate; Franck Gallardo; Karoly Toth
err分享
err收藏
LAVR-289, an Orally Bioavailable Inhibitor of Adenovirus Replication In Vitro and In VivoLAVR-289，一种口服生物可利用的腺病毒复制体外和体内抑制剂
errACS INFECTIOUS DISEASES
IF3.8
err2025-05-19
err0
PREAI
errQuentin-Froignant, Charlotte; Tollefson, Ann E.; Cline-Smith, Anna; Kappler-Gratias, Sandrine; Landrein, Nicolas; Roy, Vincent; Agrofoglio, Luigi A.; Toth, Karoly; Wodrich, Harald; Gallardo, Franck
err分享
err收藏
Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 Mpro inhibitors with improved metabolic stability
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-01-01
err0
PREAI
errGao, Shenghua; Song, Letian; Ye, Bing; Yang, Mianling; Li, Junyi; Gu, Manyu; Tollefson, Ann E.; Toth, Karoly; Zhan, Peng; Liu, Xinyong
err分享
err收藏
Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model
errVIRUSES-BASEL
IF3.5
err2024-07-26
err0
errOAAI
errTollefson, Ann E.; Cline-Smith, Anna; Spencer, Jacqueline F.; Ying, Baoling; Reyna, Dawn M.; Lipka, Elke; James, Scott H.; Toth, Karoly
err分享
err收藏
NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-07-09
err4
errOAAI
errTollefson, Ann E.; Cline-Smith, Anna B.; Spencer, Jacqueline F.; Reyna, Dawn M.; Lipka, Elke; Toth, Karoly
err分享
err收藏
The Clinical Impact of Access Site Selection for Successful Thrombolysis and Intervention in Acute Critical Lower Limb Ischaemia (RAD-ALI Registry)
errLIFE-BASEL
IF3.4
err2024-05-23
err0
errOAAI
errCsavajda, Adam; Toth, Karoly; Kovacs, Nandor; Rona, Szilard; Vamosi, Zoltan; Berta, Balazs; Kulcsar, Flora Zsofia; Bertrand, Olivier F.; Hizoh, Istvan; Ruzsa, Zoltan
err分享
err收藏
Identification of Ebselen derivatives as novel SARS-CoV-2 main protease inhibitors: Design, synthesis, biological evaluation, and structure-activity relationships exploration
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2023-12-01
err1
PREAI
errZhang, Heng; Li, Jing; Toth, Karoly; Tollefson, Ann E.; Jing, Lanlan; Gao, Shenghua; Liu, Xinyong; Zhan, Peng
err分享
err收藏
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-11-22
err11
PREAI
errGao, Shenghua; Song, Letian; Sylvester, Katharina; Mercorelli, Beatrice; Loregian, Arianna; Toth, Karoly; Weisse, Renato H.; Useini, Abibe; Straeter, Norbert; Yang, Mianling; Ye, Bing; Tollefson, Ann E.; Mueller, Christa E.; Liu, Xinyong; Zhan, Peng
err分享
err收藏
Hydrogel Delivery Device for the In Vitro and In Vivo Sustained Release of Active rhGALNS Enzyme
errPHARMACEUTICALS
IF4.8
err2023-06-27
err0
errOAAI
errFlanagan, Michael; Gan, Qi; Sheth, Saahil; Schafer, Rachel; Ruesing, Samuel; Winter, Linda E.; Toth, Karoly; Zustiak, Silviya P.; Montano, Adriana M.
err分享
err收藏
The adenovirus E1A repression domain disrupts the interaction between the TATA binding protein and the TATA box in a manner reversible by TFIIB
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err29
errOAAI
errSong, CZ; Loewenstein, PM; Toth, K; Tang, QQ; Nishikawa, A; Green, M
err分享
err收藏
Targeting Lin28 axis enhances glypican-3-CAR T cell efficacy against hepatic tumor initiating cell population靶向Lin28轴增强glypican-3-CAR T细胞对肝肿瘤起始细胞群的功效
errMOLECULAR THERAPY
IF12
err2023-03-01
err10
errOAAI
errPatra, Tapas; Cunningham, David M.; Meyer, Keith; Toth, Karoly; Ray, Ratna B.; Heczey, Andras; Ray, Ranjit
err分享
err收藏
Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening
errRSC MEDICINAL CHEMISTRY
IF3.6
err2023-01-01
err8
errOAAI
errJiang, Xiangyi; Li, Jing; Viayna, Antonio; Luque, F. Javier; Woodson, Molly; Jing, Lanlan; Gao, Shenghua; Zhao, Fabao; Xie, Minghui; Toth, Karoly; Tavis, John; Tollefson, Ann E.; Liu, Xinyong; Zhan, Peng
err分享
err收藏
Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-12-07
err24
PREAI
errGao, Shenghua; Song, Letian; Claff, Tobias; Woodson, Molly; Sylvester, Katharina; Jing, Lanlan; Weisse, Renato H.; Cheng, Yusen; Straeter, Norbert; Schaekel, Laura; Guetschow, Michael; Ye, Bing; Yang, Mianling; Zhang, Tao; Kang, Dongwei; Toth, Karoly; Tavis, John; Tollefson, Ann E.; Mueller, Christa E.; Zhan, Peng; Liu, Xinyong
err分享
err收藏
Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-09-15
err55
PREAI
errGao, Shenghua; Sylvester, Katharina; Song, Letian; Claff, Tobias; Jing, Lanlan; Woodson, Molly; Weisse, Renato H.; Cheng, Yusen; Schaekel, Laura; Petry, Marvin; Guetschow, Michael; Schiedel, Anke C.; Straeter, Norbert; Kang, Dongwei; Xu, Shujing; Toth, Karoly; Tavis, John; Tollefson, Ann E.; Mueller, Christa E.; Liu, Xinyong; Zhan, Peng
err分享
err收藏
Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2020-10-20
err16
errOAAI
errToth, Karoly; Hussein, Islam T. M.; Tollefson, Ann E.; Ying, Baoling; Spencer, Jacqueline F.; Eagar, Jessica; James, Scott H.; Prichard, Mark N.; Wold, William S. M.; Bowlin, Terry L.
err分享
err收藏
Generation and characterization of an Il2rg knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients
errDISEASE MODELS & MECHANISMS
IF3.3
err2020-01-01
err11
errOAAI
errLi, Rong; Ying, Baoling; Liu, Yanan; Spencer, Jacqueline F.; Miao, Jinxin; Tollefson, Ann E.; Brien, James D.; Wang, Yaohe; Wold, William S. M.; Wang, Zhongde; Toth, Karoly
err分享
err收藏
Drug development against human adenoviruses and its advancement by Syrian hamster models
errclinical microbiology reviews
IF12.3
err2019-03-27
err26
PREAI
errWold, William S. M.; Tollefson, Ann E.; Ying, Baoling; Spencer, Jacqueline F.; Toth, Karoly
err分享
err收藏
Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9
errVIRUSES-BASEL
IF3.5
err2018-05-06
err27
errOAAI
errMiao, Jinxin; Ying, Baoling; Li, Rong; Tollefson, Ann E.; Spencer, Jacqueline F.; Wold, William S. M.; Song, Seok-Hwan; Kong, Il-Keun; Toth, Karoly; Wang, Yaohe; Wang, Zhongde
err分享
err收藏
Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2017-09-01
err19
errOAAI
errSchaar, Katrin; Geisler, Anja; Kraus, Milena; Pinkert, Sandra; Pryshliak, Markian; Spencer, Jacqueline F.; Tollefson, Ann E.; Ying, Baoling; Kurreck, Jens; Wold, William S.; Klopfleisch, Robert; Toth, Karoly; Fechner, Henry
err分享
err收藏
HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model
errVIRUSES-BASEL
IF3.5
err2017-06-13
err12
errOAAI
errToth, Karoly; Spencer, Jacqueline F.; Ying, Baoling; Tollefson, Ann E.; Wold, William S. M.
err分享
err收藏

研究方向

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合作学者
合作期刊
P
Peter A. Ward
H 指数: 134 · 论文数: 948
B
Béla Merkely
H 指数: 106 · 论文数: 2.0K
C
Christa E. Müller
H 指数: 94 · 论文数: 1.0K
F
F. Javier Luque
H 指数: 77 · 论文数: 537
Р
Роберто Пили
H 指数: 74 · 论文数: 698
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