Aaron J. Oakley - Publications, H-index & Citations

Aaron J. Oakley

University of Wollongong

43H指数

220论文数

5.1K被引数

收录论文 47

发表时间

Development of potent glutathione transferase Omega-1 inhibitors with applications in inflammation and cancer therapy 开发具有抗炎和癌症治疗应用的高效谷胱甘肽转移酶Omega-1抑制剂

European Journal of Medicinal Chemistry

IF5.9

2025-08-23

PREAI

Yiyue Xie; Yuji Nakano; Padmaja Tummala; Aaron J. Oakley; Adi Suwandi; Matthew E. Cuellar; Jessica M. Strasser; Jayme L. Dahlin; Michael A. Walters; Marco G. Casarotto; Philip G. Board; Jonathan B. Baell

Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli

NATURE COMMUNICATIONS

IF15.7

2024-09-27

OAAI

Xu, Zhi-Qiang; Jergic, Slobodan; Lo, Allen T. Y.; Pradhan, Alok C.; Brown, Simon H. J.; Bouwer, James C.; Ghodke, Harshad; Lewis, Peter J.; Tolun, Gokhan; Oakley, Aaron J.; Dixon, Nicholas E.

AIG2A and AIG2B limit the activation of salicylic acid-regulated defenses by tryptophan-derived secondary metabolism in Arabidopsis

PLANT CELL

IF11.6

2022-08-16

OAAI

Wang, Zhixue; Yang, Leiyun; Jander, Georg; Bhawal, Ruchika; Zhang, Sheng; Liu, Zhenhua; Oakley, Aaron; Hua, Jian

Mechanism of transcription modulation by the transcription-repair coupling factor

NUCLEIC ACIDS RESEARCH

IF13.1

2022-05-31

OAAI

Paudel, Bishnu P.; Xu, Zhi-Qiang; Jergic, Slobodan; Oakley, Aaron J.; Sharma, Nischal; Brown, Simon H. J.; Bouwer, James C.; Lewis, Peter J.; Dixon, Nicholas E.; van Oijen, Antoine M.; Ghodke, Harshad

Mechanistic behavior and subtle key events during DNA clamp opening and closing in T4 bacteriophage

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2022-05-01

PREAI

Bhardwaj, Vijay Kumar; Oakley, Aaron; Purohit, Rituraj

Multiple classes and isoforms of the RNA polymerase recycling motor protein HelD

MICROBIOLOGYOPEN

IF4.6

2021-12-08

OAAI

Larsen, Joachim S.; Miller, Michael; Oakley, Aaron J.; Dixon, Nicholas E.; Lewis, Peter J.

RNA polymerases from low G+C gram-positive bacteria

TRANSCRIPTION-AUSTIN

IF4.4

2021-08-17

OAAI

Miller, Michael; Oakley, Aaron J.; Lewis, Peter J.

Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD

NATURE COMMUNICATIONS

IF15.7

2020-12-18

OAAI

Newing, Timothy P.; Oakley, Aaron J.; Miller, Michael; Dawson, Catherine J.; Brown, Simon H. J.; Bouwer, James C.; Tolun, Gokhan; Lewis, Peter J.

Shear thickening in dense non-Brownian suspensions: Viscous to inertial transition 致密的非布朗悬浮液中的剪切增稠: 粘性到惯性过渡

JOURNAL OF RHEOLOGY

IF3.2

2020-03-01

OAAI

Madraki, Y.; Oakley, A.; Nguyen Le, A.; Colin, A.; Ovarlez, G.; Hormozi, S.

Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-02-27

PREAI

Xie, Yiyue; Tummala, Padmaja; Oakley, Aaron J.; Deora, Girdhar Singh; Nakano, Yuji; Rooke, Melissa; Cuellar, Matthew E.; Strasser, Jessica M.; Dahlin, Jayme L.; Walters, Michael A.; Casarotto, Marco G.; Board, Philip G.; Baell, Jonathan B.

Atomistic Insights into Photoprotein Formation: Computational Prediction of the Properties of Coelenterazine and Oxygen Binding in Obelin

JOURNAL OF COMPUTATIONAL CHEMISTRY

IF4.8

2019-12-16

OAAI

Griffiths, Thomas M.; Oakley, Aaron J.; Yu, Haibo

Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens (vol 204, pg 396, 2018)

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2019-08-01

PREAI

McGrath, Amy E.; Martyn, Alexander P.; Whittell, Louise R.; Dawes, Fay E.; El Salamouni, Nehad S.; Beck, Jennifer L.; Dixon, Nicholas E.; Kelso, Michael J.; Oakley, Aaron J.

Crystal structures and biochemical characterization of DNA sliding clamps Chock from three Gram-negative bacterial pathogens

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2018-12-01

OAAI

McGrath, Amy E.; Martyn, Alexander P.; Whittell, Louise R.; Dawes, Fay E.; Beck, Jennifer L.; Dixon, Nicholas E.; Kelso, Michael J.; Oakley, Aaron J.

Identification of a novel tetrameric structure for human apolipoprotein-D

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2018-09-01

OAAI

Kielkopf, Claudia S.; Low, Jason K. K.; Mok, Yee-Foong; Bhatia, Surabhi; Palasovski, Tony; Oakley, Aaron J.; Whitten, Andrew E.; Garner, Brett; Brown, Simon H. J.

Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2018-07-19

PREAI

Wegener, Kate L.; McGrath, Amy E.; Dixon, Nicholas E.; Oakley, Aaron J.; Scanlon, Denis B.; Abell, Andrew D.; Bruning, John B.

Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example 回顾Hit发现文献以寻找困难的目标: 以谷胱甘肽转移酶Omega-1为例

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-04-13

PREAI

Xie, Yiyue; Dahlin, Jayme L.; Oakley, Aaron J.; Casarotto, Marco G.; Board, Philip G.; Baell, Jonathan B.

Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction

ANTIBIOTICS-BASEL

IF4.6

2018-02-22

OAAI

Chilingaryan, Zorik; Headey, Stephen J.; Lo, Allen T. Y.; Xu, Zhi-Qiang; Otting, Gottfried; Dixon, Nicholas E.; Scanlon, Martin J.; Oakley, Aaron J.

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity GSTO1-1在炎症，结肠炎和肥胖模型中起促炎作用

SCIENTIFIC REPORTS

IF3.9

2017-12-19

OAAI

Menon, Deepthi; Innes, Ashlee; Oakley, Aaron J.; Dahlstrom, Jane E.; Jensen, Lora M.; Brustle, Anne; Tummala, Padmaja; Rooke, Melissa; Casarotto, Marco G.; Baell, Jonathan B.; Nghi Nguyen; Xie, Yiyue; Cuellar, Matthew; Strasser, Jessica; Dahlin, Jayme L.; Walters, Michael A.; Burgio, Gaetan; O'Neill, Luke A. J.; Board, Philip G.

Hotspots of age-related protein degradation: the importance of neighboring residues for the formation of non-disulfide crosslinks derived from cysteine

BIOCHEMICAL JOURNAL

IF4.3

2017-07-11

OAAI

Friedrich, Michael G.; Wang, Zhen; Oakley, Aaron J.; Schey, Kevin L.; Truscott, Roger J. W.

Structural and biophysical analyses of the skeletal dihydropyridine receptor β subunit β1a reveal critical roles of domain interactions for stability

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-05-01

OAAI

Norris, Nicole C.; Joseph, Soumya; Aditya, Shouvik; Karunasekara, Yamuna; Board, Philip G.; Dulhunty, Angela F.; Oakley, Aaron J.; Casarotto, Marco G.

研究方向