Ayman M. Mahmoud - Publications, H-index & Citations

Ayman M. Mahmoud

egyptian knowledge bank (ekb)

61H指数

337论文数

1.1W被引数

收录论文 114

发表时间

Modulation of Redox Homeostasis, Inflammation, and Necroptosis by Carbocisteine Protects Against Bisphenol A-Induced Male Reproductive Toxicity 通过调节卡莫司汀对氧化还原稳态、炎症和坏死性凋亡的影响，保护 Against Bisphenol A 诱导的雄性生殖毒性

Bratislava Medical Journal

IF1.1

2026-06-01

PREAI

Alzoghaibi, Mohammed A.; Hassanein, Emad H. M.; Alotaibi, Mohammed F.; Alzoghaibi, Abdullah M.; Althagafy, Hanan S.; Qebesy, Hamada S.; Allam, Amr M. T.; Mahmoud, Ayman M.

Amelioration of cisplatin-induced myocardial injury by nanocurcumin through antioxidant, anti-inflammatory, and calcium regulatory mechanisms 纳米姜黄素通过抗氧化、抗炎和钙调控机制改善顺铂诱导的心肌损伤

Journal of Molecular Histology

IF2.2

2025-11-19

PREAI

Qamraa H. Alqahtani; Tahani A. ALMatrafi; Raeesa Mohammed; Ayman M. Mahmoud; Iman H. Hasan

Nifuroxazide attenuates bisphenol A–induced male reproductive toxicity by modulating oxidative stress, inflammation, and Nrf2/HO-1 and necroptosis pathways 尼氟硝苯通过调节氧化应激、炎症、Nrf2/HO-1和坏死性凋亡通路，减轻双酚A诱导的雄性生殖毒性。

Tissue and Cell

IF2.5

2025-11-18

PREAI

Mohammed A. Alzoghaibi; Emad H.M. Hassanein; Mohammed F. Alotaibi; Abdullah M. Alzoghaibi; Hanan S. Althagafy; Hamada S. Qebesy; Amr M.T. Allam; Ayman M. Mahmoud

Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress; TLR-4/NF-κB signaling; and necroptosis 坎地沙坦通过上调SIRT1/Nrf2/HO-1信号通路并抑制氧化应激；TLR-4/NF-κB信号通路；以及坏死性凋亡，来保护顺铂处理大鼠的主动脉结构和功能。

Frontiers in Pharmacology

IF4.8

2025-10-08

OAAI

Ayman M. Mahmoud†; Sulaiman M. Alnasser; Omnia A. M. Abd El-Ghafar; Reem S. Alruhaimi; Hanan S. Althagafy; Ahmed M. Atwa; Emad H. M. Hassanein

Protective role of S-carboxymethylcysteine against cyclophosphamide nephrotoxicity: involvement of Nrf2/HO-1 signaling and suppression of oxidative stress, inflammation, and apoptosis

MOLECULAR & CELLULAR TOXICOLOGY

IF1.4

2025-10-01

PREAI

Alruhaimi, Reem S.; Hassanein, Emad H. M.; Alnasser, Sulaiman M.; Ahmeda, Ahmad F.; Althagafy, Hanan S.; Sabry, Mostafa; Ahmed, Abdullatif A.; Mahmoud, Ayman M.

Ambroxol mitigates cyclophosphamide-induced liver injury by suppressing TLR-4/NF-κB signaling and oxidative stress and upregulating cytoglobin, TXNRD1 and HMGB1 阿莫西芬通过抑制TLR-4/NF-κB信号通路和氧化应激，并上调细胞球蛋白、TXNRD1和HMGB1，减轻环磷酰胺诱导的肝损伤。

WORLD JOURNAL OF GASTROENTEROLOGY

IF5.4

2025-09-21

PREAI

Alruhaimi, Reem S.; Hassanein, Emad H. M.; Alnasser, Sulaiman M.; Ahmeda, Ahmad F.; Althagafy, Hanan S.; Abd El-Ghafar, Omnia A. M.; Mahmoud, Ayman M.

Protective effect of ambroxol on cyclophosphamide-induced intestinal damage: involvement of oxidative stress, inflammation, and Keap-1/Nrf2/HO-1 signaling 阿布莫西林对环磷酰胺诱导的肠道损伤的保护作用：氧化应激、炎症及Keap-1/Nrf2/HO-1信号通路的参与

Journal of Molecular Histology

IF2.2

2025-09-15

PREAI

Reem S. Alruhaimi; Sulaiman M. Alnasser; Hanan S. Althagafy; Sherif M. A. Mansour; Omnia A. M. Abd El-Ghafar; Ayman M. Mahmoud; Emad H. M. Hassanein

S-Carboxymethylcysteine Mitigates Cyclophosphamide-Induced Hepatotoxicity by Modulating TLR-4/NF-κB Signaling and Redox Homeostasis S-羧甲基半胱氨酸通过调节TLR-4/NF-κB信号通路和氧化还原稳态，减轻环磷酰胺诱导的肝毒性。

BRATISLAVA MEDICAL JOURNAL

IF0

2025-09-01

PREAI

Alruhaimi, Reem S.; Alnasser, Sulaiman M.; Ahmeda, Ahmad F.; Althagafy, Hanan S.; Abd El-Ghafar, Omnia A. M.; Hassanein, Emad H. M.; Mahmoud, Ayman M.

Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430 更正：Aladaileh等人发现，Formononetin能够上调Nrf2/HO-1信号通路，并预防甲氨蝶呤诱导的大鼠发生氧化应激、炎症和肾脏损伤。Antioxidants 2019, 8, 430

Antioxidants 2025, Vol. 14, Page 1061

IF6.6

2025-08-29

OAAI

Saleem H. Aladaileh; Omnia E. Hussein; Mohammad H. Abukhalil; Sultan A. M. Saghir; May Bin-Jumah; Manal A. Alfwuaires; Mousa O. Germoush; Amer A. Almaiman; Ayman M. Mahmoud

Attenuation of NF-κB/NLRP3 inflammasome axis and oxidative stress, and upregulation of Nrf2/HO-1 signaling mediate the protective effect of S-carboxymethylcysteine against cyclophosphamide-induced cardiotoxicity NF-κB/NLRP3炎症小体轴的减弱和氧化应激的抑制，以及Nrf2/HO-1信号通路的上调，介导了S-羧甲基半胱氨酸对环磷酰胺诱导的心脏毒性的保护作用。

tissue cell

IF0

2025-08-15

PREAI

Reem S. Alruhaimi; Emad H.M. Hassanein; Sulaiman M. Alnasser; Ahmad F. Ahmeda; Hanan S. Althagafy; Amr M.T. Allam; Hamada S. Qebesy; Ayman M. Mahmoud

Selenium nanoparticles mitigate chlorpyrifos-induced nephrotoxicity by modulating oxidative stress, inflammation, and the SIRT1/Nrf2/HO-1 signaling pathway 硒纳米颗粒通过调节氧化应激、炎症和SIRT1/Nrf2/HO-1信号通路来缓解氯吡硫磷诱导的肾毒性。

Journal of Molecular Histology

IF2.2

2025-07-31

PREAI

Alaa A. A. Mahmoud; Ayman M. Mahmoud; Adel Abdel-Moneim; Sulaiman M. Alnasser; Reem S. Alruhaimi; Emad H. M. Hassanein; Sanaa M. Abd El-Twab

Attenuation of chlorpyrifos-induced liver injury, oxidative stress and inflammation by selenium nanoparticles via SIRT1/FXR/Nrf2 signaling pathway modulation 通过SIRT1/FXR/Nrf2信号通路调控，硒纳米粒子减轻了氯吡硫磷诱导的肝脏损伤、氧化应激和炎症。

Naunyn-Schmiedeberg's Archives of Pharmacology

IF3.1

2025-07-23

PREAI

Alaa A. A. Mahmoud; Sanaa M. Abd El-Twab; Sulaiman M. Alnasser; Reem S. Alruhaimi; Adel Abdel-Moneim; Emad H. M. Hassanein; Ayman M. Mahmoud

Upregulation of Nrf2/HO-1 signaling and farnesoid X receptor and attenuation of oxidative stress and inflammation mediate the protective effect of sitagliptin against diabetic nephropathy in rats Nrf2/HO-1信号通路的上调、法尼酯X受体的激活以及氧化应激和炎症的减轻，介导了西格列汀对大鼠糖尿病肾病保护作用。

International Immunopharmacology

IF4.7

2025-07-22

PREAI

Iman H. Hasan; Qamraa H. Alqahtani; Wedad S. Sarawi; Tahani A. ALMatrafi; Juman Al-Saab; Emad H.M. Hassanein; Noha A. Ahmed; Mohamed El Mohtadi; Mohamed Anany; Ayman M. Mahmoud

Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development 计算指导的蓝蓟黄素结构修饰：一种用于增强抗氧化和抗肿瘤活性以促进药物开发的创新方法

Chemical Biology & Drug Design

IF3.3

2025-07-03

OAAI

Reem S. Alruhaimi; Emadeldin M. Kamel; Sulaiman M. Alnasser; Ibrahim Elbagory; Ayman M. Mahmoud; Al Mokhtar Lamsabhi

Targeting TLR4/NF-κB signaling, oxidative stress, and apoptosis by farnesol mitigates cadmium-induced testicular toxicity in rats 靶向TLR4/NF-κB信号通路、氧化应激和凋亡，法尼醇能够减轻镉诱导的大鼠睾丸毒性。

TISSUE & CELL

IF2.5

2025-06-01

PREAI

Hassanein, Emad H. M.; Alotaibi, Mohammed F.; Alruhaimi, Reem S.; Sabry, Mostafa; Sayed, Ghadir A.; Atwa, Ahmed M.; Mahmoud, Ayman M.

Estrogen induces the alternative activation of macrophages through binding to estrogen receptor-alpha 雌激素通过结合雌激素受体-α诱导巨噬细胞的替代性活化。

EXPERIMENTAL AND MOLECULAR PATHOLOGY

IF3.7

2025-05-31

OAAI

Amina Belboul; Jason Ashworth; Abdulmannan Fadel; Jessica Mcloughlin; Ayman Mahmoud; Mohamed El Mohtadi

Comprehensive Phytochemical, Antioxidant, and Antibacterial Analysis of Vitex agnus-castus L. Essential Oil (VACEO): Insights from ADMET and Molecular Docking Studies 综合Vitex agnus-castus L.精油（VACEO）的植物化学成分、抗氧化和抗菌分析：来自ADMET和分子对接研究的见解

PHARMACEUTICALS

IF4.8

2025-03-25

OAAI

Azzouni, Dounia; Mrani, Soukaina Alaoui; Bahij, Fadoua; Zejli, Hind; Alanazi, Mohammed M.; Fadili, Driss; El Moussaoui, Abdelfattah; Mahmoud, Ayman M.; Taleb, Mustapha

Effects of Fe substitution by Al on the structure and magnetic properties of BaFe10Al2O19 hexaferrites Fe替换为Al对BaFe10Al2O19六方铁氧体结构和磁性能的影响

EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS

IF2.3

2025-02-05

PREAI

Koutzarova, T.; Krezhov, K.; Peneva, P.; Kolev, S.; Tran, L. M.; Georgieva, B.; Mahmoud, A.; Boschini, F.; Vetruyen, B.; Closset, R.

Diallyl disulfide prevents cadmium-induced testicular injury by attenuating oxidative stress, apoptosis, and TLR-4/NF-κB and JAK1/STAT3 signaling and upregulating SIRT1 in rats

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

IF3.3

2024-12-01

PREAI

Hassanein, Emad H. M.; Alotaibi, Mohammed F.; Alruhaimi, Reem S.; Abd El-Ghafar, Omnia A. M.; Mohammad, Mostafa K.; Atwa, Ahmed M.; Mahmoud, Ayman M.

Integrating Computational Modeling and Experimental Validation to Unveil Tyrosinase Inhibition Mechanisms of Flavonoids from Alhagi graecorum

ACS OMEGA

IF4.3

2024-11-13

OAAI

Alruhaimi, Reem S.; Mahmoud, Ayman M.; Alnasser, Sulaiman M.; Alotaibi, Mohammed F.; Elbagory, Ibrahim; El-Bassuony, Ashraf A.; Lamsabhi, Al Mokhtar; Kamel, Emadeldin M.

研究方向