Patricia C. Salinas - Publications, H-index & Citations

Patricia C. Salinas

university of london

47H指数

130论文数

9.3K被引数

收录论文 43

发表时间

Progressive changes in synapses and glial cells in AppNL-G-F mice, a model of Alzheimer's disease 阿尔茨海默病模型appnl-g-f小鼠突触和神经胶质细胞的进行性变化

BRAIN COMMUNICATIONS

IF4.5

2026-01-01

OAAI

Tomlin, Megan; Podpolny, Marina; Salinas, Patricia C.

Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model 在阿尔茨海默氏病中升高的Wnt拮抗剂Dickkopf-3下调，在疾病小鼠模型中恢复突触完整性和记忆

ELIFE

IF0

2024-01-29

OAAI

Martin Flores, Nuria; Podpolny, Marina; Mcleod, Faye; Workman, Isaac; Crawford, Karen; Ivanov, Dobril; Leonenko, Ganna; Escott-Price, Valentina; Salinas, Patricia C.

S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus

DEVELOPMENTAL CELL

IF8.7

2023-10-01

OAAI

Teo, Samuel; Bossio, Alessandro; Stamatakou, Eleanna; Pascual-Vargas, Patricia; Jones, Megan E.; Schuhmacher, Laura-Nadine; Salinas, Patricia C.

A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease

SCIENCE ADVANCES

IF12.5

2023-01-13

OAAI

Jones, Megan E.; Buchler, Johanna; Dufor, Tom; Palomer, Ernest; Teo, Samuel; Martin-Flores, Nuria; Boroviak, Katharina; Metzakopian, Emmanouil; Gibb, Alasdair; Salinas, Patricia C.

Structural Analysis and Development of Notum Fragment Screening Hits

ACS CHEMICAL NEUROSCIENCE

IF3.9

2022-06-22

OAAI

Zhao, Yuguang; Mahy, William; Willis, Nicky J.; Woodward, Hannah L.; Steadman, David; Bayle, Elliott D.; Atkinson, Benjamin N.; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Harlos, Karl; Jeganathan, Fiona; Constantinou, Stefan; Costa, Artur; Kjaer, Svend; Bictash, Magda; Salinas, Patricia C.; Whiting, Paul; Vincent, Jean-Paul; Fish, Paul, V; Jones, E. Yvonne

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-05-10

OAAI

Willis, Nicky J.; Mahy, William; Sipthorp, James; Zhao, Yuguang; Woodward, Hannah L.; Atkinson, Benjamin N.; Bayle, Elliott D.; Svensson, Fredrik; Frew, Sarah; Jeganathan, Fiona; Monaghan, Amy; Benvegnu, Stefano; Jolly, Sarah; Vecchia, Luca; Ruza, Reinis R.; Kjaer, Svend; Howell, Steven; Snijders, Ambrosius P.; Bictash, Magda; Salinas, Patricia C.; Vincent, Jean-Paul; Jones, E. Yvonne; Whiting, Paul; Fish, Paul, V

Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters

MOLECULAR PSYCHIATRY

IF10.1

2022-03-16

OAAI

Palomer, Ernest; Martin-Flores, Nuria; Jolly, Sarah; Pascual-Vargas, Patricia; Benvegnu, Stefano; Podpolny, Marina; Teo, Samuel; Vaher, Kadi; Saito, Takashi; Saido, Takaomi C.; Whiting, Paul; Salinas, Patricia C.

Miro1-dependent mitochondrial dynamics in parvalbumin interneurons

ELIFE

IF0

2021-06-30

OAAI

Kontou, Georgina; Antonoudiou, Pantelis; Podpolny, Marina; Szulc, Blanka R.; Arancibia-Carcamo, I. Lorena; Higgs, Nathalie F.; Lopez-Domenech, Guillermo; Salinas, Patricia C.; Mann, Edward O.; Kittler, Josef T.

Wnt-Frizzled Signaling Regulates Activity-Mediated Synapse Formation

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2021-06-14

OAAI

Teo, Samuel; Salinas, Patricia C.

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-10-30

OAAI

Mahy, William; Willis, Nicky J.; Zhao, Yuguang; Woodward, Hannah L.; Svensson, Fredrik; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Hillier, James; Kjaer, Svend; Frew, Sarah; Monaghan, Amy; Bictash, Magda; Salinas, Patricia C.; Whiting, Paul; Vincent, Jean-Paul; Jones, E. Yvonne; Fish, Paul, V

Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo 网格蛋白轻链多样性在体外调节膜变形和在体内调节突触小泡形成

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-09-09

OAAI

Redlingshofer, Lisa; McLeod, Faye; Chen, Yu; Camus, Marine D.; Burden, Jemima J.; Palomer, Ernest; Briant, Kit; Dannhauser, Philip N.; Salinas, Patricia C.; Brodsky, Frances M.

Restoring neuron connections

SCIENCE

IF45.8

2020-08-28

OAAI

Salinas, Patricia C.

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-03

OAAI

Aprile, Francesco A.; Sormanni, Pietro; Podpolny, Marina; Chhangur, Shianne; Needham, Lisa-Maria; Ruggeri, Francesco S.; Perni, Michele; Limbocker, Ryan; Heller, Gabriella T.; Sneideris, Tomas; Scheidt, Tom; Mannini, Benedetta; Habchi, Johnny; Lee, Steven F.; Salinas, Patricia C.; Knowles, Tuomas P. J.; Dobson, Christopher M.; Vendruscolo, Michele

Single-Cell Quantification of mRNA Expression in The Human Brain

SCIENTIFIC REPORTS

IF3.9

2019-08-26

OAAI

Jolly, Sarah; Lang, Verena; Koelzer, Viktor Hendrik; Frigerio, Carlo Sala; Magno, Lorenza; Salinas, Patricia C.; Whiting, Paul; Palomer, Ernest

Wnt Signaling Deregulation in the Aging and Alzheimer's Brain

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2019-05-22

167

OAAI

Palomer, Ernest; Buechler, Johanna; Salinas, Patricia C.

Wnt7b signalling through Frizzled-7 receptor promotes dendrite development by coactivating CaMKII and JNK

JOURNAL OF CELL SCIENCE

IF3.6

2018-07-09

OAAI

Ferrari, Maria E.; Bernis, Maria E.; McLeod, Faye; Podpolny, Marina; Coullery, Romina P.; Casadei, Inelia M.; Salinas, Patricia C.; Rosso, Silvana B.

Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

CELL REPORTS

IF6.9

2018-04-01

OAAI

McLeod, Faye; Bossio, Alessandro; Marzo, Aude; Ciani, Lorenza; Sibilla, Sara; Hannan, Saad; Wilson, Gemma A.; Palomer, Ernest; Smart, Trevor G.; Gibb, Alasdair; Salinas, Patricia C.

Gender Equality from a European Perspective: Myth and Reality

NEURON

IF15

2017-11-01

OAAI

Salinas, Patricia C.; Bagni, Claudia

Hippocampus: Activity-Driven Maturation of Neural Circuits for Navigation

CURRENT BIOLOGY

IF7.5

2017-06-01

OAAI

Cacucci, Francesca; Salinas, Patricia; Wills, Thomas J.

Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus

CURRENT BIOLOGY

IF7.5

2016-10-01

111

OAAI

Marzo, Aude; Galli, Soledad; Lopes, Douglas; McLeod, Faye; Podpolny, Marina; Segovia-Roldan, Margarita; Ciani, Lorenza; Purro, Silvia; Cacucci, Francesca; Gibb, Alasdair; Salinas, Patricia C.

研究方向