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M

Matthias Quick

columbia university irving medical center

37H指数
181论文数
5.3K被引数
收录论文 75
发表时间
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Identification of genetic markers of quinine partial resistance in Plasmodium falciparum鉴定恶性疟原虫中奎宁部分耐药性的遗传标记
errNature Microbiology
IF19.4
err2026-07-06
err0
errOAAI
errMariko Kanai; Sachel Mok; Tomas Yeo; Melanie J. Shears; Jin H. Jeon; Sunil K. Narwal; Leila S. Ross; Kharizta Wiradiputri; Meseret T. Haile; Abhai K. Tripathi; Godfree Mlambo; Jonathan Kim; Eva Gil-Iturbe; Heekuk Park; Tolla Ndiaye; John Okombo; Kurt E. Ward; Felix D. Rozenberg; Kate J. Fairhurst; Sydney M. Gavula; Talia S. Bloxham; Jessica L. Bridgford; Tanaya Sheth; Manuel Llinás; Marcus C. S. Lee; Jennifer L. Small-Saunders; Filippo Mancia; Matthias Quick; Anne-Catrin Uhlemann; Photini Sinnis; David Armand Fidock
err分享
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Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistanceZY19489与哌喹之间的交叉高敏性中和了PfCRT介导的药物外排和恶性疟原虫抗性
errNature Communications
IF15.7
err2026-04-01
err0
errOAAI
errJohn Okombo; Tolla Ndiaye; Tarrick Qahash; Igor M. R. Moura; Eva Gil-Iturbe; Laura M. Hagenah; Jessica L. Bridgford; Vinicius Bonatto; Kurt E. Ward; Tomas Yeo; Sunil K. Narwal; Lily V. Orta; Isla Anderson; Satish K. Dhingra; Charisse Flerida A. Pasaje; Heekuk Park; Jonathan Kim; Rafael V. C. Guido; Maria Belén Jiménez-Diaz; Iñigo Angulo-Barturen; Jacquin C. Niles; Filippo Mancia; Anne-Catrin Uhlemann; Sachel Mok; Matthias Quick; Elizabeth A. Winzeler; Didier Leroy; Manuel Llinás; Vandana Thathy; David A. Fidock
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Mechanistic snapshots of lipid-linked sugar transfer脂质连接糖转移的机制快照
errNature Communications
IF15.7
err2025-12-06
err0
errOAAI
errRyan T. Morgan; Stefano Motta; Eva Gil-Iturbe; Biddut Bhattacharjee; Mohammad T. Anwar; Giovanni Di Muccio; Alice Romagnoli; Bedangshu Mishra; Khuram U. Ashraf; Injin Bang; Daniele Di Marino; Todd L. Lowary; Matthias Quick; Vasileios I. Petrou; Michael H. B. Stowell; Rie Nygaard; Filippo Mancia
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Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)阴离子脂质对阴离子交换蛋白1 (AE1)构象转变能量景观的影响
errNature Communications
IF15.7
err2025-11-26
err0
errOAAI
errTianle Chen; Francesca Vallese; Eva Gil-Iturbe; Kookjoo Kim; Tito Calì; Matthias Quick; Oliver B. Clarke; Emad Tajkhorshid
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A comparative analysis reveals electrogenic properties of PfCRT and pendrin比较分析揭示了PfCRT和pendrin的生电特性。
errJournal of Biological Chemistry
IF3.9
err2025-08-26
err0
PREAI
errEva Gil-Iturbe; Matthias Quick
err分享
err收藏
A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants一种具有多阶段抗疟活性且与PfCRT和PfMDR1突变体缺乏交叉抗性的新型4-氨基喹啉化学型
errPLOS PATHOGENS
IF4.9
err2024-10-29
err0
errOAAI
errFerreira, Leticia Tiburcio; Cassiano, Gustavo Capatti; Alvarez, Luis Carlos Salazar; Okombo, John; Calit, Juliana; Fontinha, Diana; Gil-Iturbe, Eva; Coyle, Rachael; Andrade, Carolina Horta; Sunnerhagen, Per; Bargieri, Daniel Youssef; Prudencio, Miguel; Quick, Matthias; Cravo, Pedro V.; Lee, Marcus C. S.; Fidock, David A.; Costa, Fabio Trindade Maranhao
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Alternating access of a bacterial homolog of neurotransmitter: sodium symporters determined from AlphaFold2 ensembles and DEER spectroscopy
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-09-20
err0
errOAAI
errSchwartz, Alexandra C.; Stein, Richard A.; Gil-Iturbe, Eva; Quick, Matthias; Mchaourab, Hassane S.
err分享
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Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology
errMBIO
IF4.7
err2024-01-16
err3
errOAAI
errHagenah, Laura M.; Dhingra, Satish K.; Small-Saunders, Jennifer L.; Qahash, Tarrick; Willems, Andreas; Schindler, Kyra A.; Rangel, Gabriel W.; Gil-Iturbe, Eva; Kim, Jonathan; Akhundova, Emiliya; Yeo, Tomas; Okombo, John; Mancia, Filippo; Quick, Matthias; Roepe, Paul D.; Llinas, Manuel; Fidock, David A.
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Mechanism of anion exchange and small-molecule inhibition of pendrin
errNATURE COMMUNICATIONS
IF15.7
err2024-01-06
err2
errOAAI
errWang, Lie; Hoang, Anthony; Gil-Iturbe, Eva; Laganowsky, Arthur; Quick, Matthias; Zhou, Ming
err分享
err收藏
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness
errSCIENCE ADVANCES
IF12.5
err2023-11-10
err5
errOAAI
errMok, Sachel; Yeo, Tomas; Hong, Davin; Shears, Melanie J.; Ross, Leila S.; Ward, Kurt E.; Dhingra, Satish K.; Kanai, Mariko; Bridgford, Jessica L.; Tripathi, Abhai K.; Mlambo, Godfree; Burkhard, Anna Y.; Ansbro, Megan R.; Fairhurst, Kate J.; Gil-Iturbe, Eva; Park, Heekuk; Rozenberg, Felix D.; Kim, Jonathan; Mancia, Filippo; Fairhurst, Rick M.; Quick, Matthias; Uhlemann, Anne-Catrin; Sinnis, Photini; Fidock, David A.
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Insight into the mechanism of H+- coupled nucleobase transport深入了解H偶联核碱基转运的机制
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-08-07
err5
errOAAI
errWeng, Jun; Zhou, Xiaoming; Wiriyasermkul, Pattama; Ren, Zhenning; Chen, Kehan; Gil-Iturbe, Eva; Zhou, Ming; Quick, Matthias
err分享
err收藏
Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance
errPLOS PATHOGENS
IF4.9
err2022-02-07
err23
errOAAI
errSmall-Saunders, Jennifer L.; Hagenah, Laura M.; Wicht, Kathryn J.; Dhingra, Satish K.; Deni, Ioanna; Kim, Jonathan; Vendome, Jeremie; Gil-Iturbe, Eva; Roepe, Paul D.; Mehta, Monica; Mancia, Filippo; Quick, Matthias; Eppstein, Margaret J.; Fidock, David A.
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Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia
errCANCER DISCOVERY
IF33.3
err2022-01-19
err21
errOAAI
errGalan-Diez, Marta; Borot, Florence; Ali, Abdullah Mahmood; Zhao, Junfei; Gil-Iturbe, Eva; Shan, Xiaochuan; Luo, Na; Liu, Yongfeng; Huang, Xi-Ping; Bisikirska, Brygida; Labella, Rossella; Kurland, Irwin; Roth, Bryan L.; Quick, Matthias; Mukherjee, Siddhartha; Rabadan, Raul; Carroll, Martin; Raza, Azra; Kousteni, Stavroula
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Insight into the direct interaction of Na+ with NhaA and mechanistic implications
errSCIENTIFIC REPORTS
IF3.9
err2021-03-29
err11
errOAAI
errQuick, Matthias; Dwivedi, Manish; Padan, Etana
err分享
err收藏
Crystal structures of LeuT reveal conformational dynamics in the outward-facing states
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-01-01
err9
errOAAI
errFan, Jianjun; Xiao, Yang; Quick, Matthias; Yang, Yuwei; Sun, Ziyi; Javitch, Jonathan A.; Zhou, Xiaoming
err分享
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A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition
errEMBO JOURNAL
IF8.3
err2020-11-06
err20
errOAAI
errFocht, Dorota; Neumann, Caroline; Lyons, Joseph; Bilbao, Ander Eguskiza; Blunck, Rickard; Malinauskaite, Lina; Schwarz, Ilona O.; Javitch, Jonathan A.; Quick, Matthias; Nissen, Poul
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X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release
errNATURE COMMUNICATIONS
IF15.7
err2020-02-21
err33
errOAAI
errGotfryd, Kamil; Boesen, Thomas; Mortensen, Jonas S.; Khelashvili, George; Quick, Matthias; Terry, Daniel S.; Missel, Julie W.; LeVine, Michael V.; Gourdon, Pontus; Blanchard, Scott C.; Javitch, Jonathan A.; Weinstein, Harel; Loland, Claus J.; Nissen, Poul; Gether, Ulrik
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The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-07-19
err21
errOAAI
errLeVine, Michael V.; Terry, Daniel S.; Khelashvili, George; Siegel, Zarek S.; Quick, Matthias; Javitch, Jonathan A.; Blanchard, Scott C.; Weinstein, Harel
err分享
err收藏
New Roles for Peripheral Dopamine D2-Like Receptors in Antipsychotic Drug-Induced Metabolic Dysfunction外周多巴胺D2-Like受体在抗精神病药物引起的代谢功能障碍中的新作用
errBIOLOGICAL PSYCHIATRY
IF9
err2019-05-01
err0
PREAI
errFreyberg, Zachary; Farino, Zachary; Morgenstern, Travis; Maffei, Antonella; Quick, Matthias; De Solis, Alain; Wiriyasermkul, Pattama; Freyberg, Robin; Aslanoglou, Despoina; Sorisio, Denise; Inbar, Benjamin; Free, R. Benjamin; Donthamsetti, Prashant; Mosharov, Eugene; Kellendonk, Christoph; Schwartz, Gary; Sibley, David; Schmauss, Claudia; Zeltser, Lori; Moore, Holly; Harris, Paul; Javitch, Jonathan
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New roles for dopamine D2and D3receptors in pancreatic beta cell insulin secretion
errMOLECULAR PSYCHIATRY
IF10.1
err2019-01-09
err60
errOAAI
errFarino, Zachary J.; Morgenstern, Travis J.; Maffei, Antonella; Quick, Matthias; De Solis, Alain J.; Wiriyasermkul, Pattama; Freyberg, Robin J.; Aslanoglou, Despoina; Sorisio, Denise; Inbar, Benjamin P.; Free, R. Benjamin; Donthamsetti, Prashant; Mosharov, Eugene, V; Kellendonk, Christoph; Schwartz, Gary J.; Sibley, David R.; Schmauss, Claudia; Zeltser, Lori M.; Moore, Holly; Harris, Paul E.; Javitch, Jonathan A.; Freyberg, Zachary
err分享
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研究方向

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合作期刊
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H 指数: 128 · 论文数: 723
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J
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H 指数: 99 · 论文数: 432
D
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H 指数: 95 · 论文数: 425
E
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H 指数: 93 · 论文数: 374
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