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DNMT3B PWWP mutations cause hypermethylation of heterochromatin Taglini, Francesca; Kafetzopoulos, Ioannis; Rolls, Willow; Musialik, Kamila Irena; Lee, Heng Yang; Zhang, Yujie; Marenda, Mattia; Kerr, Lyndsay; Finan, Hannah; Rubio-Ramon, Cristina; Gautier, Philippe; Wapenaar, Hannah; Kumar, Dhananjay; Davidson-Smith, Hazel; Wills, Jimi; Murphy, Laura; Wheeler, Ann; Wilson, Marcus; Sproul, Duncan 分享 收藏
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis Kiss, Robert S.; Chicoine, Jarred; Khalil, Youssef; Sladek, Robert; Chen, He; Pisaturo, Alessandro; Martin, Cyril; Dale, Jessica D.; Brudenell, Tegan A.; Kamath, Archith; Kyei-Boahen, Jeffrey; Hafiane, Anouar; Daliah, Girija; Alecki, Celia; Hopes, Tayah S.; Heier, Martin; Aligianis, Irene A.; Lebrun, Jean -Jacques; Aspden, Julie; Paci, Emanuele; Kerksiek, Anja; Luetjohann, Dieter; Clayton, Peter; Wills, Jimi C.; von Kriegsheim, Alex; Nilsson, Tommy; Sheridan, Eamonn; Handley, Mark T. 分享 收藏
Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer Titmarsh, Helen F.; von Kriegsheim, Alex; Wills, Jimi C.; O'Connor, Richard A.; Dhaliwal, Kevin; Frame, Margaret C.; Pattle, Samuel B.; Dorward, David A.; Byron, Adam; Akram, Ahsan R. 分享 收藏
Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells Altea-Manzano, Patricia; Vandekeere, Anke; Edwards-Hicks, Joy; Roldan, Mar; Abraham, Emily; Lleshi, Xhordi; Guerrieri, Ania Naila; Berardi, Domenica; Wills, Jimi; Junior, Jair Marques; Pantazi, Asimina; Acosta, Juan Carlos; Sanchez-Martin, Rosario M.; Fendt, Sarah-Maria; Martin-Hernandez, Miguel; Finch, Andrew J. 分享 收藏
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MYC sensitises cells to apoptosis by driving energetic demand Edwards-Hicks, Joy; Su, Huizhong; Mangolini, Maurizio; Yoneten, Kubra K.; Wills, Jimi; Rodriguez-Blanco, Giovanny; Young, Christine; Cho, Kevin; Barker, Heather; Muir, Morwenna; Guerrieri, Ania Naila; Li, Xue-Feng; White, Rachel; Manasterski, Piotr; Mandrou, Elena; Wills, Karen; Chen, Jingyu; Abraham, Emily; Sateri, Kianoosh; Qian, Bin-Zhi; Bankhead, Peter; Arends, Mark; Gammoh, Noor; von Kriegsheim, Alex; Patti, Gary J.; Sims, Andrew H.; Acosta, Juan Carlos; Brunton, Valerie; Kranc, Kamil R.; Christophorou, Maria; Pearce, Erika L.; Ringshausen, Ingo; Finch, Andrew J. 分享 收藏
The RNA-bound proteome of MRSA reveals post-transcriptional roles for helix-turn-helix DNA-binding and Rossmann-fold proteins Chu, Liang-Cui; Arede, Pedro; Li, Wei; Urdaneta, Erika C.; Ivanova, Ivayla; McKellar, Stuart W.; Wills, Jimi C.; Frohlich, Theresa; von Kriegsheim, Alexander; Beckmann, Benedikt M.; Granneman, Sander 分享 收藏
mTORC1 activity is supported by spatial association with focal adhesions Rabanal-Ruiz, Yoana; Byron, Adam; Wirth, Alexander; Madsen, Ralitsa; Sedlackova, Lucia; Hewitt, Graeme; Nelson, Glyn; Stingele, Julian; Wills, Jimi C.; Zhang, Tong; Zeug, Andre; Faessler, Reinhard; Vanhaesebroeck, Bart; Maddocks, Oliver D. K.; Ponimaskin, Evgeni; Carroll, Bernadette; Korolchuk, Viktor, I 分享 收藏
A Role for the Autophagic Receptor, SQSTM1/p62 in Trafficking NF-κB/RelA to Nucleolar Aggresomes Lobb, Ian T.; Morin, Pierre; Martin, Kirsty; Thoms, Hazel C.; Wills, Jimi C.; Lleshi, Xhordi; Olsen, Karl C. F.; Duncan, Rory R.; Stark, Lesley A. 分享 收藏
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The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity Sirey, Tamara M.; Roberts, Kenny; Haerty, Wilfried; Bedoya-Reina, Oscar; Rogatti-Granados, Sebastian; Tan, Jennifer Y.; Li, Nick; Heather, Lisa C.; Carter, Roderick N.; Cooper, Sarah; Finch, Andrew J.; Wills, Jimi; Morton, Nicholas M.; Marques, Ana Claudia; Ponting, Chris P. 分享 收藏
ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy ITPase缺乏导致致命的婴儿扩张型心肌病的Martsolf样综合征 Handley, Mark T.; Reddy, Kaalak; Wills, Jimi; Rosser, Elisabeth; Kamath, Archith; Halachev, Mihail; Falkous, Gavin; Williams, Denise; Cox, Phillip; Meynert, Alison; Raymond, Eleanor S.; Morrison, Harris; Brown, Stephen; Allan, Emma; Aligianis, Irene; Jackson, Andrew P.; Ramsahoye, Bernard H.; von Kriegsheim, Alex; Taylor, Robert W.; Finch, Andrew J.; FitzPatrick, David R. 分享 收藏
Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours Selli, Cigdem; Turnbull, Arran K.; Pearce, Dominic A.; Li, Ang; Fernando, Anu; Wills, Jimi; Renshaw, Lorna; Thomas, Jeremy S.; Dixon, J. Michael; Sims, Andrew H. 分享 收藏
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KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability KDM3A协调肌动蛋白动力学与鞭毛内运输以调节纤毛稳定性 Yeyati, Patricia L.; Schiller, Rachel; Mali, Girish; Kasioulis, Ioannis; Kawamura, Akane; Adams, Ian R.; Playfoot, Christopher; Gilbert, Nick; van Heyningen, Veronica; Wills, Jimi; von Kriegsheim, Alex; Finch, Andrew; Sakai, Juro; Schofield, Christopher J.; Jackson, Ian J.; Mill, Pleasantine 分享 收藏
Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions Guitart, Amelie V.; Panagopoulou, Theano I.; Villacreces, Arnaud; Vukovic, Milica; Sepulveda, Catarina; Allen, Lewis; Carter, Roderick N.; van de Lagemaat, Louie N.; Morgan, Marcos; Giles, Peter; Sas, Zuzanna; Gonzalez, Marta Vila; Lawson, Hannah; Paris, Jasmin; Edwards-Hicks, Joy; Schaak, Katrin; Subramani, Chithra; Gezer, Deniz; Armesilla-Diaz, Alejandro; Wills, Jimi; Easterbrook, Aaron; Coman, David; So, Chi Wai Eric; O'Carroll, Donal; Vernimmen, Douglas; Rodrigues, Neil P.; Pollard, Patrick J.; Morton, Nicholas M.; Finch, Andrew; Kranc, Kamil R. 分享 收藏
HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation Myant, Kevin B.; Cammareri, Patrizia; Hodder, Michael C.; Wills, Jimi; Von Kriegsheim, Alex; Gyorffy, Balazs; Rashid, Mamun; Polo, Simona; Maspero, Elena; Vaughan, Lynsey; Gurung, Basanta; Barry, Evan; Malliri, Angeliki; Camargo, Fernando; Adams, David J.; Iavarone, Antonio; Lasorella, Anna; Sansom, Owen J. 分享 收藏
Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches Byrne, Kate M.; Monsefi, Naser; Dawson, John C.; Degasperi, Andrea; Bukowski-Wills, Jimi-Carlo; Volinsky, Natalia; Dobrzynski, Maciej; Birtwistle, Marc R.; Tsyganov, Mikhail A.; Kiyatkin, Anatoly; Kida, Katarzyna; Finch, Andrew J.; Carragher, Neil O.; Kolch, Walter; Nguyen, Lan K.; von Kriegsheim, Alex; Kholodenko, Boris N. 分享 收藏
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