logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
G

Guangzhou Han

Hanson Institute
H指数:11
被引数:1,479

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Lead change of a HIF-2a antagonist guided by multiparameter optimization and utilization of an Olp? p*Ar interaction
MEDICINAL CHEMISTRY RESEARCH
IF3.1
2023-07-182
OA
Wehn, Paul M.; Yang, Song; Grina, Jonas A.; Rizzi, James P.; Schlachter, Stephen T.; Wang, Bin; Xu, Rui; Yang, Hanbiao; Du, Xinlin; Han, Guangzhou; Wang, Keshi; Czerwinski, Robert M.; Ged, Emily L.; Huang, Heli; Halfmann, Megan M.; Maddie, Melissa A.; Morton, Emily R.; Olive, Sarah R.; Tan, Huiling; Xie, Shanhai; Josey, John A.; Wallace, Eli M.
3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-06-24157
OAAI
Xu, Rui; Wang, Keshi; Rizzi, James P.; Huang, Heli; Grina, Jonas A.; Schlachter, Stephen T.; Wang, Bin; Wehn, Paul M.; Yang, Hanbiao; Dixon, Darryl D.; Czerwinski, Robert M.; Du, Xinlin; Ged, Emily L.; Han, Guangzhou; Tan, Huiling; Wong, Tai; Xie, Shanhai; Josey, John A.; Wallace, Eli M.
Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate (S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-10-0591
PREAI
Wehn, Paul M.; Rizzi, James P.; Dixon, Darryl D.; Grina, Jonas A.; Schlachter, Stephen T.; Wang, Bin; Xu, Rui; Yang, Hanbiao; Du, Xinlin; Han, Guangzhou; Wang, Keshi; Cao, Zhaodan; Cheng, Tzuling; Czerwinski, Robert M.; Goggin, Barry S.; Huang, Heli; Halfmann, Megan M.; Maddie, Melissa A.; Morton, Emily L.; Olive, Sarah R.; Tan, Huiling; Xie, Shanhai; Wong, Tai; Josey, John A.; Wallace, Eli M.
PT2977, a novel HIF-2a antagonist, has potent antitumor activity and remodels the immunosuppressive tumor microenvironment in clear cell renal cell cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2018-01-012
PRE
Wong, Tai W.; Shrimali, Rajeev; Contreras, Cristina; Cheng, Tzuling; Czerwinski, Robert M.; Dixon, Daryl D.; Du, Xinlin; Fett, Craig; Goree, Jessica; Grina, Jonas A.; Han, Guangzhou; Huang, Heli; Rizzi, Jim; Schlachter, Stephen T.; Wang, Bin; Wang, Keshi; Wehn, Paul M.; Xie, Shanhai; Xu, Rui; Yang, Hanbiao; Josey, John A.; Wallace, Eli M.
A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
CANCER RESEARCH
IF16.6
2016-09-15253
OAAI
Wallace, Eli M.; Rizzi, James P.; Han, Guangzhou; Wehn, Paul M.; Cao, Zhaodan; Du, Xinlin; Cheng, Tzuling; Czerwinski, Robert M.; Dixon, Darryl D.; Goggin, Barry S.; Grina, Jonas A.; Halfmann, Megan M.; Maddie, Melissa A.; Olive, Sarah R.; Schlachter, Stephen T.; Tan, Huiling; Wang, Bin; Wang, Keshi; Xie, Shanhai; Xu, Rui; Yang, Hanbiao; Josey, John A.

研究方向

暂未获取到该数据
S
Shanhai Xie
H 指数:16论文数:56被引数:5,440
J
John A. Josey
H 指数:26论文数:69被引数:4,361
R
Rui Xu
H 指数:33论文数:145被引数:4,267
P
Paul M. Wehn
H 指数:15论文数:35被引数:2,188
R
Robert Czerwiński
H 指数:28论文数:126被引数:2,890
J
Jonas Grina
H 指数:17论文数:45被引数:1,314
S
Stephen T. Schlachter
H 指数:16论文数:42被引数:1,410
H
Hanbiao Yang
H 指数:19论文数:62被引数:2,175
X
Xinlin Du
H 指数:17论文数:54被引数:4,638
K
Keshi Wang
H 指数:9论文数:46被引数:1,151