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Co-exposure to polystyrene nanoplastics and F-53B induces vascular endothelial cell pyroptosis through the NF-κB/NLRP3 pathway 共暴露于聚苯乙烯纳米塑料和F-53B通过NF-κB/NLRP3通路诱导血管内皮细胞焦亡 Lv, Junli; Tan, Zhenzhen; An, Ziwen; Xu, Rui; Zhang, Huaxing; Guo, Mingmei; Xiao, Fang; Zhao, Mengwei; Guo, Yi; Liu, Yi; Liu, Xuehui; Ma, Jingtao; Guo, Huicai 分享 收藏
BBO-10203, an orally bioavailable small molecule that disrupts the RAS-PI3Kα interaction leading to pAKT and tumor growth inhibition in models of breast, lung and colorectal cancer Simanshu, D.; Xu, R.; Stice, J.; Czyzyk, D.; Feng, S.; Yang, Y.; Denson, J. P.; Riegler, E.; Zhang, C.; Fu, L.; Lin, K.; Lightstone, F. C.; Wang, K.; Stephen, A. G.; Maciag, A. E.; Sinkevicius, K.; Nissley, D. V.; Wallace, E. M.; McCormick, F.; Beltran, P. 分享 收藏
Primary Cutaneous Mucormycosis Caused by Mucor irregularis in a Chinese Man Li, Zhihua; Jiang, Qing; Tao, Xiaohua; Zhang, Zhenhua; Shi, Luhuai; Cheng, Lifang; He, Pingxiu; Fan, Xinyi; Xu, Rui; Luo, Yunpeng; Gao, Yangmin 分享 收藏
BBO-10203, a first-in-class, orally bioavailable, selective covalent small molecule that inhibits RAS- driven PI3Kalpha activity without affecting glucose metabolism Beltran, Pedro; Dhirendra, Simanshu; Xu, Rui; Chen, Ming; Czyzyk, Daniel; Donovan, Sofia; Feng, Siyu; Feng, Cindy; Fu, Lijuan; Lightstone, Felice; Lin, Ken; Maciag, Anna; Nissley, Dwight; Riegler, Erin; Sinkevicius, Kerstin; Stephen, Andrew; Stice, James; Turner, David; Wang, Bin; Wang, Keshi; Yang, Yue; Zhang, Cathy; McCormick, Frank; Wallace, Eli 分享 收藏
BBO-8520, a first-in-class, direct inhibitor of KRASG12C (ON), locks GTP-bound KRASG12C in the state 1 conformation resulting in rapid and complete blockade of effector binding Maciag, Anna E.; Stice, James; Wang, Bin; Sharma, Alok; Chan, Albert; Lin, Ken; Singh, Devansh; Dyba, Marcin; Yang, Yue; Setoodeh, Saman; Smith, Brian P.; Rabara, Dana; Zhang, Zuhui; Larsen, Erik K.; Esposito, Dom; Denson, John Paul; Ranieri, Michela; Meynardie, Mary; Mehdizadeh, Sadaf; Alexander, Patrick; Blanco, Maria Abreu; Turner, David; Xu, Rui; Lightstone, Felice C.; Wong, Kwok Kin; Simanshu, Dhirendra; Wang, Keshi; Stephen, Andrew G.; Sinkevicius, Kerstin; Nissley, Dwight V.; Wallace, Eli; McCormick, Frank; Beltran, Pedro J. 分享 收藏
Interlayer coupling modulated tunable magnetic states in superlattice MnBi2Te4(Bi2Te3)n topological insulators Guo, Jianfeng; Wang, Huan; Zhang, Haoyan; Mi, Shuo; Li, Songyang; Dong, Haoyu; Zhu, Shiyu; Hu, Jiawei; Wang, Xueyun; Li, Yanjun; Sugawara, Yasuhiro; Xu, Rui; Pang, Fei; Ji, Wei; Xia, Tianlong; Cheng, Zhihai 分享 收藏
A novel method for high level production of protein glutaminase by sfGFP tag in Bacillus subtilis Zhang, Zheng; Li, Yuxi; Zheng, Lihui; Jin, Mingfei; Wu, Yelin; Xu, Rui; Luo, Yin; Wu, Jiajing; Su, Wei; Luo, Shijing; Huang, Yuchen; Wang, Cong; Chang, Zhongyi; Jiang, Deming; Huang, Jing 分享 收藏
SIM1811-03 (SIM0235), an anti-tumor necrosis factor receptor-2 (TNFR2) monoclonal antibody, in patients with advanced solid tumor and/or cutaneous T cell lymphomas (CTCL): Preliminary results from an on-going first-in-human phase I trial in China Liu, F.; Yang, N.; Wang, J.; Wang, R.; Han, Z.; Yang, C.; Li, J.; Liu, Z.; Li, Y.; Tang, J.; Cui, A.; Xu, R. 分享 收藏
Lead change of a HIF-2a antagonist guided by multiparameter optimization and utilization of an Olp? p*Ar interaction Wehn, Paul M.; Yang, Song; Grina, Jonas A.; Rizzi, James P.; Schlachter, Stephen T.; Wang, Bin; Xu, Rui; Yang, Hanbiao; Du, Xinlin; Han, Guangzhou; Wang, Keshi; Czerwinski, Robert M.; Ged, Emily L.; Huang, Heli; Halfmann, Megan M.; Maddie, Melissa A.; Morton, Emily R.; Olive, Sarah R.; Tan, Huiling; Xie, Shanhai; Josey, John A.; Wallace, Eli M. 分享 收藏
Cardiolipin and OPA1 Team up for Methamphetamine-Induced Locomotor Activity by Promoting Neuronal Mitochondrial Fusion in the Nucleus Accumbens of Mice Wang, Liang; Wei, Qingfan; Xu, Rui; Chen, Yaxing; Li, Shu; Bu, Qian; Zhao, Ying; Li, Hongchun; Zhao, Yue; Jiang, Linhong; Chen, Yuanyuan; Dai, Yanping; Zhao, Yinglan; Cen, Xiaobo 分享 收藏
N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling Zeng, Qinghe; Xu, Rui; Ling, Houfu; Zhao, Shan; Wang, Xu; Yuan, Wenhua; Gu, Mancang; Xu, Taotao; Wang, Pinger; Ruan, Hongfeng; Jin, Hongting; Qu, Hangbo; Ye, Fusheng; Chen, Jiali 分享 收藏
Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime Liu, Xiaocong; Wei, Qingfan; Yang, Xiaowei; Wang, Xiaojie; Zhang, Jiamei; Xu, Rui; Zhang, Haoluo; Wang, Shaomin; Wan, Xuemei; Jiang, Linhong; He, Yuman; Li, Shu; Chen, Rong; Wang, Yonghai; Chen, Yaxing; Qin, Feng; Chen, Yuanyuan; Dai, Yanping; Li, Hongchun; Zhao, Ying; Zhang, Huaqin; Bu, Qian; Wang, Hongbo; Tian, Jingwei; Zhao, Yinglan; Cen, Xiaobo 分享 收藏
mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1-GluA2 interaction in the nucleus accumbens mTOR通过伏隔核中的SynDIG1-GluA2相互作用调节可卡因诱导的行为敏化 Li, Hong-chun; Zhang, Jia-mei; Xu, Rui; Wang, Yong-hai; Xu, Wei; Chen, Rong; Wan, Xue-mei; Zhang, Hao-luo; Wang, Liang; Wang, Xiao-jie; Jiang, Lin-hong; Liu, Bin; Zhao, Ying; Chen, Yuan-yuan; Dai, Yan-ping; Li, Min; Zhang, Hua-qin; Yang, Zhen; Bai, Lin; Zhang, Jie; Wang, Hong-bo; Tian, Jing-wei; Zhao, Ying-lan; Cen, Xiao-bo 分享 收藏
Simvastatin Blocks Reinstatement of Cocaine-induced Conditioned Place Preference in Male Mice with Brain Lipidome Remodeling Xu, Wei; He, Yuman; Zhang, Jiamei; Li, Hongchun; Wan, Xuemei; Li, Menglu; Wang, Yonghai; Xu, Rui; Zhang, Haoluo; Dai, Yanping; Liu, Haxiaoyu; Jiang, Linhong; Zhao, Ying; Cen, Xiaobo 分享 收藏
Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice Wang, Xiaojie; Wang, Liang; Luo, Mingyi; Bu, Qian; Liu, Chunqi; Jiang, Linhong; Xu, Rui; Wang, Shaomin; Zhang, Haoluo; Zhang, Jiamei; Wan, Xuemei; Li, Hongchun; Wang, Yonghai; Liu, Bin; Zhao, Ying; Chen, Yuanyuan; Dai, Yanping; Li, Min; Wang, Hongbo; Tian, Jingwei; Zhao, Yinglan; Cen, Xiaobo 分享 收藏
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Defining disease progression in Chinese mainland people: Association between bone mineral density and knee osteoarthritis Fang, Liang; Xia, Chenjie; Xu, Huihui; Ge, Qinwen; Shi, Zhenyu; Kong, Liya; Zhang, Peng; Xu, Rui; Zou, Zhen; Wang, Pinger; Jin, Hongting; Tong, Peijian 分享 收藏
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