未登录 Monocolonization with Bacteroides thetaiotaomicron exerts region-specific effects on Alzheimer's disease-related traits in the murine brain 单菌定植脆弱拟杆菌对小鼠大脑中阿尔茨海默病相关特征具有区域特异性影响 Nguyen, Vu Thu Thuy; Konig, Svenja; Formes, Henning; Al Taleb, Zukaa; Steinert, Florian; Bufe, Bernd; Eggert, Simone; Stegmuller, Simone; Schermer, Yannik; Richling, Elke; Kins, Stefan; Reinhardt, Christoph; Endres, Kristina 分享 收藏
APP family member dimeric complexes are formed predominantly in synaptic compartments Schilling, Sandra; August, Alexander; Meleux, Mathieu; Conradt, Carolin; Tremmel, Luisa M.; Teigler, Sandra; Adam, Virginie; Mueller, Ulrike C.; Koo, Edward H.; Kins, Stefan; Eggert, Simone 分享 收藏
Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity Schilling, Sandra; Pradhan, Ajay; Heesch, Amelie; Helbig, Andrea; Blennow, Kaj; Koch, Christian; Bertgen, Lea; Koo, Edward H.; Brinkmalm, Gunnar; Zetterberg, Henrik; Kins, Stefan; Eggert, Simone 分享 收藏
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The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif Eggert, Simone; Gruebl, Tomas; Rajender, Ritu; Rupp, Carsten; Sander, Bianca; Heesch, Amelie; Zimmermann, Marius; Hoepfner, Sebastian; Zentgraf, Hanswalter; Kins, Stefan 分享 收藏
Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA Eggert, Simone; Gonzalez, A. C.; Thomas, C.; Schilling, S.; Schwarz, S. M.; Tischer, C.; Adam, V.; Strecker, P.; Schmidt, V.; Willnow, T. E.; Hermey, G.; Pietrzik, C. U.; Koo, E. H.; Kins, Stefan 分享 收藏
Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction Feilen, Lukas P.; Haubrich, Kevin; Strecker, Paul; Probst, Sabine; Eggert, Simone; Stier, Gunter; Sinning, Irmgard; Konietzko, Uwe; Kins, Stefan; Simon, Bernd; Wild, Klemens 分享 收藏
LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State Herr, Uta-Mareike; Strecker, Paul; Storck, Steffen E.; Thomas, Carolin; Rabiej, Verena; Junker, Anne; Schilling, Sandra; Schmidt, Nadine; Dowds, C. Marie; Eggert, Simone; Pietrzik, Claus U.; Kins, Stefan 分享 收藏
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Lysine 624 of the Amyloid Precursor Protein (APP) Is a Critical Determinant of Amyloid β Peptide Length SUPPORT FOR A SEQUENTIAL MODEL OF γ-SECRETASE INTRAMEMBRANE PROTEOLYSIS AND REGULATION BY THE AMYLOID β PRECURSOR PROTEIN (APP) JUXTAMEMBRANE REGION Kukar, Thomas L.; Ladd, Thomas B.; Robertson, Paul; Pintchovski, Sean A.; Moore, Brenda; Bann, Maralyssa A.; Ren, Zhao; Jansen-West, Karen; Malphrus, Kim; Eggert, Simone; Maruyama, Hiroko; Cottrell, Barbara A.; Das, Pritam; Basi, Guriqbal S.; Koo, Edward H.; Golde, Todd E. 分享 收藏
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PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2 Kuan, Yung-Hui; Gruebl, Tomas; Soba, Peter; Eggert, Simone; Nesic, Iva; Back, Simone; Kirsch, Joachim; Beyreuther, Konrad; Kins, Stefan 分享 收藏
Homo- and hetero-dimerization of APP family members promotes intercellular adhesion (vol 24, pg 3624, 2005) Soba, P; Eggert, S; Wagner, K; Zentgraf, H; Siehl, K; Kreger, S; Löwer, A; Langer, A; Merdes, G; Paro, R; Müller, U; Kins, S; Beyreuther, K 分享 收藏
Homo- and heterodimerization of APP family members promotes intercellular adhesion Soba, P; Eggert, S; Wagner, K; Zentgraf, H; Siehl, K; Kreger, S; Löwer, A; Langer, A; Merdes, G; Paro, R; Masters, CL; Müller, U; Kins, S; Beyreuther, K 分享 收藏
The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves α-, β-, γ-, and ε-like cleavages -: Modulation of APLP-1 processing by N-glycosylation Eggert, S; Paliga, K; Soba, P; Evin, G; Masters, CL; Weidemann, A; Beyreuther, K 分享 收藏
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