Jagadeesh Kumar Gangasani

department of pharmacology & toxicology

15H指数

47论文数

615被引数

收录论文 13

发表时间

Targeting PIP5K ameliorates hepatic cancer by inhibiting PI3K/AKT and the autophagy mechanism and enhancing ROS-mediated apoptosis 靶向PIP5K通过抑制PI3K/AKT和自噬机制并增强ROS介导的凋亡来改善肝癌

Frontiers in Pharmacology

IF4.8

2026-05-08

OAAI

PA P. A. Shantanu; BR Bishal Rajdev; NP N. P. Syamprasad; JK Jagadeesh Kumar Gangasani; AM Arijit Mandal; SR Samir Ranjan Panda; RS Ramakrishna Sistla; SB Sai Balaji Andugulapati; SK Shiv Kumar Sarin; DM Dinesh Mani Tripathi; VG V. G. M. Naidu

NARI-29: A Novel Epalrestat Derivative Attenuates Pulmonary Fibrosis by Modulating the TGF-β/Smad Signaling NARI-29：一种新型依帕列斯特衍生物通过调节TGF-β/Smad信号通路减轻肺纤维化

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-05-09

PREAI

Andugulapati, SB; Kambhampati, V; Eedara, A; Gangasani, JK; Kumar, BH; Naidu, VGM

Exploration of the cytotoxic and microtubule disruption potential of novel imidazo[1,5-a]pyridine-based chalcones

RSC MEDICINAL CHEMISTRY

IF3.6

2025-01-01

OAAI

Gopathi, Ramu; Kumar, Mommuleti Pradeep; Kumar, Gangasani Jagadeesh; Syamprasad, N. P.; Kodiripaka, Bheeshma Geetanjali; Naidu, V. G. M.; Babu, Bathini Nagendra

AKR1B1 drives hyperglycemia-induced metabolic reprogramming in MASLD-associated hepatocellular carcinoma AKR1B1在MASLD相关肝细胞癌中驱动高血糖诱导的代谢重编程

JHEP REPORTS

IF7.5

2024-02-01

OAAI

Syamprasad, N. P.; Jain, Siddhi; Rajdev, Bishal; Panda, Samir Ranjan; Kumar, Gangasani Jagadeesh; Shaik, Khaja Moinuddin; Shantanu, P. A.; Challa, Veerabhadra Swamy; Jorvekar, Sachin B.; Borkar, Roshan M.; Vaidya, Jayathirtha Rao; Tripathi, Dinesh Mani; Naidu, V. G. M.

Molecular dissection of anti-colon cancer activity of NARI-29: special focus on H2O2 modulated NF-κB and death receptor signaling

FREE RADICAL RESEARCH

IF2.9

2023-08-07

PREAI

Syamprasad, N. P.; Rajdev, Bishal; Jain, Siddhi; Gangasani, Jagadeesh Kumar; Vaidya, Jayathirtha Rao; Naidu, V. G. M.

Pivotal role of AKR1B1 in pathogenesis of colitis associated colorectal carcinogenesis

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2023-06-01

PREAI

Syamprasad, N. P.; Rajdev, Bishal; Jain, Siddhi; Panda, Samir Ranjan; Puppala, Eswara Rao; Chaudhari, Pradip; Vaidya, Jayathirtha Rao; Kumar, Gangasani Jagadeesh; Naidu, V. G. M.

Bio-nanoconjugates of lithocholic acid/IR 780 for ROS-mediated apoptosis and optoacoustic imaging applications in breast cancer

COLLOIDS AND SURFACES B-BIOINTERFACES

IF5.6

2023-01-01

PREAI

Ghosh, Aparajita; Rajdev, Bishal; Parihar, Nidhi; Ponneganti, Srikanth; Das, Pintu; Naidu, V. G. M.; Krishnanand, P. Radha; Murty, U. S. N.; Kumar, Jagadeesh; Pemmaraju, Deepak B.

Nutraceutical prospects of Houttuynia cordata against the infectious viruses

FOOD BIOSCIENCE

IF5.9

2022-12-01

OAAI

Ghosh, Aparajita; Ghosh, Bijoyani; Parihar, Nidhi; Ilaweibaphyrnai, Myrthong; Panda, Samir R.; Alexander, Amit; Chella, Naveen; Usn, Murty; Vgm, Naidu; Kumar, Jagadeesh; Pemmaraju, Deepak B.

Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo experimental models

PHYTOMEDICINE

IF8.3

2022-03-01

PREAI

Puppala, Eswara Rao; Jain, Siddhi; Saha, Pritam; Rachamalla, Mahesh; Syamprasad, N. P.; Yalamarthi, Sai Sudha; Abubakar, Md.; Chaudhary, Antra; Chamundeswari, D.; Murty, U. S. N.; Gangasani, Jagadeesh Kumar; Naidu, V. G. M.

Lithocholic acid-tryptophan conjugate (UniPR126) based mixed micelle as a nano carrier for specific delivery of niclosamide to prostate cancer via EphA2 receptor

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2021-08-01

PREAI

Jannu, Arun Kumar; Puppala, Eswara Rao; Gawali, Basveshwar; Syamprasad, N. P.; Alexander, Amit; Marepally, Srujan; Chella, Naveen; Gangasani, Jagadeesh Kumar; Naidu, V. G. M.

Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function

STROKE

IF8.9

2019-02-01

OAAI

Bieber, Michael; Schuhmann, Michael K.; Volz, Julia; Kumar, Gangasani Jagadeesh; Vaidya, Jayathirtha Rao; Nieswandt, Bernhard; Pham, Mirko; Stoll, Guido; Kleinschnitz, Christoph; Kraft, Peter

IITZ-01, a novel potent lysosomotropic autophagy inhibitor, has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo

ONCOGENE

IF7.3

2018-08-30

PREAI

Guntuku, Lalita; Gangasani, Jagadeesh Kumar; Thummuri, Dinesh; Borkar, Roshan M.; Manavathi, Bramanandam; Ragampeta, Srinivas; Vaidya, Jayathirtha Rao; Sistla, Ramakrishna; Vegi, Naidu G. M.

2-Azetidinones: Synthesis and biological evaluation as potential anti-breast cancer agents 2-氮杂环丁酮: 作为潜在抗乳腺癌药物的合成和生物学评价

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-11-01

PREAI

Geesala, Ramasatyaveni; Gangasani, Jagadeesh Kumar; Budde, Mahender; Balasubramanian, Sridhar; Vaidya, Jayathirtha Rao; Das, Amitava

研究方向