Christopher W. Pugh - Publications, H-index & Citations

Christopher W. Pugh

University of Oxford

81H指数

289论文数

4.3W被引数

收录论文 87

发表时间

Systemic hypoxia or Foxp3-directed Phd2 silencing cause immune activation and augment the protective immune response to BCG 系统性缺氧或Foxp3介导的Phd2沉默导致免疫激活并增强对BCG的保护性免疫应答

Communications Biology

IF5.1

2026-09-24

OAAI

Marie Sion; Elena Stylianou; Rachel Tanner; Atsushi Yamamoto; Hisashi Hashimoto; Kento Kawai; Nawamin Pinpathomrat; Masateru Uchiyama; Aneesha Bhandari; Tammie Bishop; Katherine R. Bull; Tanya L. Crockford; Samvid Kurlekar; Alex Spencer; Philip Macklin; Oliver McCallion; Maria Prange-Barczynska; Peter J. Ratcliffe; Thomas Riffelmacher; Joanna Hester; Fadi Issa; Helen McShane; Chris W. Pugh

Stabilisation of HIF signalling in the mouse epicardium extends embryonic potential and neonatal heart regeneration

ELIFE

IF0

2025-10-22

PREAI

Gamen, Elisabetta; Price, Eleanor L.; Pezzolla, Daniela; De Villiers, Carla; Gunadasa-Rohling, Mala; Lokman, Adam B.; Cosma, Maria-Alexa; Sayers, Judith; Silva, Carolina Roque; Salama, Rafik; Mole, David Robert; Bishop, Tammie; Pugh, Chris W.; Choudhury, Robin P.; Carr, Carolyn A.; Vieira, Joaquim Miguel; Riley, Paul R.

HIFα isoform specific activities drive cell-type specificity of VHL-associated oncogenesis HIFα亚型特异性活性驱动VHL相关肿瘤发生的细胞类型特异性

Nature Communications

IF15.7

2025-10-16

OAAI

Joanna D.C.C. Lima; Madeleine Hooker; Ran Li; Ayslan B. Barros; Norma Masson; Christopher W. Pugh; David R. Mole; Julie Adam; Peter J. Ratcliffe; Samvid Kurlekar

The role of hypoxia inducible factor modulation and defatting in discarded steatotic human livers preserved with normothermic machine perfusion (NMP): observations from an ex-situ whole blood transplant model.

TRANSPLANTATION

IF5

2024-09-16

PREAI

Abbas, Syed Hussain; Shaheed, Sadr; Quaglia, Alberto; Morovat, Alireza; Dengu, Fungai; Ebeling, Georg; Sagar, Alex; Ceresa, Carlo; Hodson, Leanne; Pugh, Christopher; Friend, Peter

Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells (vol 15, 3448 , 2024)

NATURE COMMUNICATIONS

IF15.7

2024-04-24

OAAI

Barnkob, Mike B.; Michaels, Yale S.; Andre, Violaine; Macklin, Philip S.; Gileadi, Uzi; Valvo, Salvatore; Rei, Margarida; Kulicke, Corinna; Chen, Ji-Li; Jain, Vitul; Woodcock, Victoria K.; Colin-York, Huw; Hadjinicolaou, Andreas V.; Kong, Youxin; Mayya, Viveka; Mazet, Julie M.; Mead, Gracie-Jennah; Bull, Joshua A.; Rijal, Pramila; Pugh, Christopher W.; Townsend, Alain R.; Gerard, Audrey; Olsen, Lars R.; Fritzsche, Marco; Fulga, Tudor A.; Dustin, Michael L.; Jones, E. Yvonne; Cerundolo, Vincenzo

Unwelcome changes to the Specialised Foundation Programme recruitment

LANCET

IF88.5

2024-04-01

OAAI

Barratt, Jonathan; Sharp, Debbie; Dhillo, Waljit S.; Pugh, Christopher

Identification of early oncogenic lesions following concomitant Vhl and Pbrm1 loss in the murine kidney

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lima, Joanna; Kurlekar, Samvid; Masson, Norma; Barros, Ayslan B.; Soares, Maria Fernanda; Pugh, Christopher W.; Adam, Julie; Ratcliffe, Peter J.

HIF1A and HIF2A differentially contribute to early and adaptive changes following in vivo Vhl inactivation in the kidney

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Kurlekar, Samvid; Lima, Joanna; Barros, Ayslan B.; Masson, Norma; Zhai, Sophia; Pugh, Christopher W.; Adam, Julie; Ratcliffe, Peter J.

Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney

CANCER RESEARCH

IF16.6

2024-03-19

OAAI

Kurlekar, Samvid; Lima, Joanna D. C. C.; Li, Ran; Lombardi, Olivia; Masson, Norma; Barros, Ayslan B.; Pontecorvi, Virginia; Mole, David R.; Pugh, Christopher W.; Adam, Julie; Ratcliffe, Peter J.

Lung Ultrasound Reproducibly Outperforms Computed Tomography in the Detection of Extravascular Lung Water in Patients Undergoing Haemodialysis

DIAGNOSTICS

IF3.3

2024-03-11

OAAI

Corcoran, John P.; Hew, Mark; Attwood, Ben; Shyamsundar, Murali; Sutherland, Sheera; Ventura, Kristine; Benamore, Rachel; St. Noble, Victoria; Piotrowska, Hania E.; Pugh, Christopher W.; Laursen, Christian B.; Gleeson, Fergus V.; Rahman, Najib M.

A peer-volunteer led active ageing programme to prevent decline in physical function in older people at risk of mobility disability (Active, Connected, Engaged [ACE]): study protocol for a randomised controlled trial 一项由同伴志愿者领导的积极老龄化计划，以防止有行动不便风险的老年人的身体功能下降 (主动，联系，参与 [ACE]): 一项随机对照试验的研究方案

TRIALS

IF2

2023-11-29

OAAI

Stathi, Afroditi; Withall, Janet; Crone, Diane; Hawley-Hague, Helen; Playle, Rebecca; Frew, Emma; Fenton, Sally; Hillsdon, Melvyn; Pugh, Christopher; Todd, Chris; Jolly, Kate; Cavill, Nick; Western, Max; Roche, Sarah; Kirby, Nigel; Boulton, Elisabeth; Thompson, Janice; Chatwin, Katie; Davies, Amy; Szekeres, Zsofia; Greaves, Colin

Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice PHD3-/-小鼠的异常交感肾上腺发育和全身性低血压

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

188

OAAI

Bishop, Tammie; Gallagher, Denis; Pascual, Alberto; Lygate, Craig A.; de Bono, Joseph P.; Nicholls, Lynn G.; Ortega-Saenz, Patricia; Oster, Henrik; Wijeyekoon, Bhathiya; Sutherland, Andrew I.; Grosfeld, Alexandra; Aragones, Julian; Schneider, Martin; van Geyte, Katie; Teixeira, Dania; Diez-Juan, Antonio; Lopez-Barneo, Jose; Channon, Keith M.; Maxwell, Patrick H.; Pugh, Christopher W.; Davies, Alun M.; Carmeliet, Peter; Ratcliffe, Peter J.

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

933

OAAI

Raval, RR; Lau, KW; Tran, MGB; Sowter, HM; Mandriota, SJ; Li, JL; Pugh, CW; Maxwell, PH; Harris, AL; Ratcliffe, PJ

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation (vol 23, pg 927, 2022)

NATURE IMMUNOLOGY

IF27.6

2022-07-19

OAAI

Mirchandani, Ananda S.; Jenkins, Stephen J.; Bain, Calum C.; Sanchez-Garcia, Manuel A.; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M.; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R.; Dickinson, Rebecca. S.; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M.; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J.; Rostron, Anthony J.; Baillie, J. Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A. John; Dockrell, David H.; Schwarze, Juergen; Hirani, Nikhil; Ratcliffe, Peter J.; Pugh, Christopher W.; Kranc, Kamil; Forbes, Stuart J.; Whyte, Moira K. B.; Walmsley, Sarah R.

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

NATURE IMMUNOLOGY

IF27.6

2022-05-27

OAAI

Mirchandani, Ananda S.; Jenkins, Stephen J.; Bain, Calum C.; Sanchez-Garcia, Manuel A.; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M.; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R.; Dickinson, Rebecca S.; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M.; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J.; Rostron, Anthony J.; Baillie, J. Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A. John; Dockrell, David H.; Schwarze, Jurgen; Hirani, Nikhil; Ratcliffe, Peter J.; Pugh, Christopher W.; Kranc, Kamil; Forbes, Stuart J.; Whyte, Moira K. B.; Walmsley, Sarah R.

Multiparameter persistent homology landscapes identify immune cell spatial patterns in tumors 多参数持续同源景观识别肿瘤中的免疫细胞空间模式

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-10-08

OAAI

Vipond, Oliver; Bull, Joshua A.; Macklin, Philip S.; Tillmann, Ulrike; Pugh, Christopher W.; Byrne, Helen M.; Harrington, Heather A.

Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia

CIRCULATION RESEARCH

IF16.2

2021-04-16

OAAI

Jatho, Aline; Zieseniss, Anke; Brechtel-Curth, Katja; Yamamoto, Atsushi; Coleman, Mathew L.; Vergel Leon, Ana M.; Biggs, Daniel; Davies, Ben; Pugh, Chris W.; Ratcliffe, Peter J.; Katschinski, Doerthe M.

Combining multiple spatial statistics enhances the description of immune cell localisation within tumours

SCIENTIFIC REPORTS

IF3.9

2020-10-29

OAAI

Bull, Joshua A.; Macklin, Philip S.; Quaiser, Tom; Braun, Franziska; Waters, Sarah L.; Pugh, Chris W.; Byrne, Helen M.

Accelerometer-measured physical activity and functional behaviours among people on dialysis

CLINICAL KIDNEY JOURNAL

IF4.6

2020-08-31

OAAI

Nawab, Khizr A.; Storey, Benjamin C.; Staplin, Natalie; Walmsley, Rosemary; Haynes, Richard; Sutherland, Sheera; Crosbie, Sarah; Pugh, Christopher W.; Harper, Charlie H. S.; Landray, Martin J.; Doherty, Aiden; Herrington, William G.

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2020-03-23

OAAI

Cheng, Xiaotong; Prange-Barczynska, Maria; Fielding, James W.; Zhang, Minghao; Burrell, Alana L.; Lima, Joanna Dcc; Eckardt, Luise; La Argles, Isobel; Pugh, Christopher W.; Buckler, Keith J.; Robbins, Peter A.; Hodson, Emma J.; Bruick, Richard K.; Collinson, Lucy M.; Rastinejad, Fraydoon; Bishop, Tammie; Ratcliffe, Peter J.

研究方向