Chengbiao Wu

university of california san diego

H指数:37

被引数:8,478

个人简介

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教育背景

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荣誉奖项

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Correlations of PSEN1, PSEN2, and APP missense variants on the production of Aβ peptides against variant effect prediction

PSEN1、PSEN2和APP错义变异与Aβ肽生成及变异效应预测的相关性

Alzheimers & Dementia-Translational Research & Clinical Interventions

IF6.8

2026-09-080

OAAI

Axonopathy: mechanisms and potential therapeutic targets for neurodegenerative diseases

轴突病变：机制及神经退行性疾病的潜在治疗靶点

Translational Neurodegeneration

IF15.2

2026-03-240

OAAI

Deciphering gain-of-function from loss-of-function variants with AlphaMissense: A case study with the mechanosensitive PIEZO1 ion channel protein

利用AlphaMissense区分功能获得性与功能缺失性变异：以力学敏感的PIEZO1离子通道蛋白为例

Biochemistry and Biophysics Reports

IF2.2

2026-02-010

OAAI

Predicting the impact of missense mutations on an unresolved protein's stability, structure, and function: A case study of Alzheimer's disease-associated TREM2 R47H variant

预测未解析蛋白质的错义突变对其稳定性、结构和功能的影响：以阿尔茨海默病相关TREM2 R47H变异为例

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

IF4.1

2025-01-011

OAAI

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis (vol 87, pg 963, 2015)

NEURON

IF15

2024-12-010

OAAI

Brain-derived neurotrophic factor plays with TRiC: focus on synaptic dysfunction in Huntington's disease

NEURAL REGENERATION RESEARCH

IF6.7

2024-09-240

OAAI

BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2024-06-012

OAAI

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2023-11-130

OAAI

Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2023-10-013

OAAI

Hippocampal Reduction of α-Synuclein via RNA Interference Improves Neuropathology in Alzheimer's Disease Mice

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2023-07-250

OAAI

Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy

NEUROBIOLOGY OF DISEASE

IF5.6

2023-03-014

OAAI

CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons

NATURE COMMUNICATIONS

IF15.7

2023-02-0817

OAAI

Lipid Nanoparticle Delivery of Chemically Modified NGFR100W mRNA Alleviates Peripheral Neuropathy

化学修饰的NGFR100W mRNA的脂质纳米颗粒递送减轻周围神经病变

ADVANCED HEALTHCARE MATERIALS

IF9.6

2022-11-1825

PRE

Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus

朊病毒诱导早期Arc反应和随后的海马mGluR5减少

NEUROBIOLOGY OF DISEASE

IF5.6

2022-10-015

OAAI

Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory Neuropathy

COMMUNICATIONS BIOLOGY

IF5.1

2022-07-1810

OAAI

Mechanism of AD risk gene RIN3 in AD early pathogenesis

JOURNAL OF THE NEUROLOGICAL SCIENCES

IF3.2

2021-10-010

PRE

Acute spinal cord injury: Pathophysiology and pharmacological intervention

急性脊髓损伤: 病理生理学和药物干预

MOLECULAR MEDICINE REPORTS

IF3.5

2021-03-3198

OAAI

Acidic fibroblast growth factor attenuates type 2 diabetes-induced demyelination via suppressing oxidative stress damage

CELL DEATH & DISEASE

IF9.6

2021-01-2132

OAAI

DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress

DL-3-n-butylphthalide通过增强PI3K/Akt信号和抑制氧化应激改善糖尿病相关的认知功能下降

ACTA PHARMACOLOGICA SINICA

IF8.4

2021-01-1876

OAAI

A missense point mutation in nerve growth factor (NGFR100W) results in selective peripheral sensory neuropathy

PROGRESS IN NEUROBIOLOGY

IF6.1

2020-11-015

OAAI

Chengbiao Wu

个人简介

教育背景

工作经历

荣誉奖项

研究方向