Joo-Youn Lee

korea research institute of chemical technology

H指数:16

被引数:867

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Discovery of a New Tetrahydroquinoline-Based Chemotype for STING Inhibition with In Vivo Efficacy against Acute Kidney Injury

发现一种基于四氢喹啉的新型化学骨架，用于STING抑制，并具有治疗急性肾损伤的体内疗效

Journal of Medicinal Chemistry

IF6.8

2026-04-180

PRE

2-Amido-3-aryl-4-methyl-thiazole derivatives as broad-spectrum anti-rhinoviral agents

2-酰胺基-3-芳基-4-甲基-噻唑衍生物作为广谱抗鼻病毒剂

European Journal of Medicinal Chemistry

IF5.9

2025-11-060

PRE

Discovery of a selective dual-specificity tyrosine phosphorylation-regulated kinase 1B inhibitor with anti-adipogenic and anti-diabetic activities

发现一种具有抗脂肪生成和抗糖尿病活性的选择性双特异性酪氨酸磷酸化调控激酶1B抑制剂

Frontiers in Pharmacology

IF4.8

2025-07-290

Blocking S1P4 signaling attenuates brain injury in mice with ischemic stroke

阻断S1P4信号通路可减轻小鼠缺血性脑卒中中的脑损伤

Journal of Advanced Research

IF13

2025-02-120

OAAI

7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication

7-氨基-3-苯基-2-甲基-吡唑并嘧啶衍生物抑制人鼻病毒复制

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-10-012

OAAI

Experimental Validation of the Neurotrophic Factor-α1 Binding Site on the Serotonin Receptor 1E (HTR1E) Responsible for β-Arrestin Activation and Subsequent Neuroprotection

ACS OMEGA

IF4.3

2024-09-160

OAAI

Constitutive activation mechanism of a class C GPCR

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-02-085

PRE

Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad-spectrum anti-rhinoviral agents (vol 15, pg 704, 2024)

RSC MEDICINAL CHEMISTRY

IF3.6

2024-01-010

OAAI

Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad-spectrum anti-rhinoviral agents

RSC MEDICINAL CHEMISTRY

IF3.6

2024-01-014

PRE

Discovery of novel amidobenzimidazole derivatives as orally available small molecule modulators of stimulator of interferon genes for cancer immunotherapy

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-12-013

PRE

Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-03-2219

PRE

Current Progress in the Development of Hepatitis B Virus Capsid Assembly Modulators: Chemical Structure, Mode-of-Action and Efficacy

MOLECULES

IF4.6

2021-12-0730

OAAI

Aristolactam BIII, a naturally derived DYRK1A inhibitor, rescues Down syndrome-related phenotypes

PHYTOMEDICINE

IF8.3

2021-11-0112

OAAI

Radicicol Inhibits Chikungunya Virus Replication by Targeting Nonstructural Protein 2

Radicicol通过靶向非结构蛋白2抑制基孔肯雅病毒复制

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2021-06-177

The Impact on Infectivity and Neutralization Efficiency of SARS-CoV-2 Lineage B.1.351 Pseudovirus

VIRUSES-BASEL

IF3.5

2021-04-0738

OAAI

Structure-Based Virtual Screening: Identification of a Novel NS2B-NS3 Protease Inhibitor with Potent Antiviral Activity against Zika and Dengue Viruses

MICROORGANISMS

IF4.2

2021-03-0620

OAAI

Sulfamoylbenzamide-based Capsid Assembly Modulators for Selective Inhibition of Hepatitis B Viral Replication

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2021-02-0214

Exploring the Mechanism of Gyejibokryeong-hwan against Atherosclerosis Using Network Pharmacology and Molecular Docking

PLANTS-BASEL

IF4.1

2020-12-1017

OAAI

Verification of the Necessity of the Tolyl Group of PF-543 for Sphingosine Kinase 1 Inhibitory Activity

MOLECULES

IF4.6

2020-05-275

OAAI

In Vitro and In Vivo Antiviral Activity of Nylidrin by Targeting the Hemagglutinin 2-Mediated Membrane Fusion of Influenza A Virus

通过靶向甲型流感病毒的血凝素2介导的膜融合，Nylidrin的体外和体内抗病毒活性

VIRUSES-BASEL

IF3.5

2020-05-2511

OAAI

Joo-Youn Lee

个人简介

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