Amit K. Gupta - Publications, H-index & Citations

Amit K. Gupta

council of scientific & industrial research (csir) - india

21H指数

75论文数

1.2K被引数

收录论文 18

发表时间

Small-Molecule Inhibition of KRAS through Conformational Selection

ACS OMEGA

IF4.3

2023-08-18

OAAI

Pagba, Cynthia V.; Gupta, Amit K.; Gorfe, Alemayehu A.

KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement

ACS BIO & MED CHEM AU

IF4.3

2022-09-26

OAAI

Pagba, CynthiaV.; Gupta, Amit K.; Naji, Ali K.; van der Hoeven, Dharini; Churion, Kelly; Liang, Xiaowen; Jakubec, Jacob; Hook, Magnus; Zuo, Yan; Martinez de Kraatz, Marisela; Frost, Jeffrey A.; Gorfe, Alemayehu A.

Overexpression and repression of key rate-limiting enzymes (acetyl CoA carboxylase and HMG reductase) to enhance fatty acid production fromRhodotorula mucilaginosa

JOURNAL OF BASIC MICROBIOLOGY

IF2.7

2020-09-08

PREAI

Chaturvedi, Shivani; Gupta, Amit K.; Bhattacharya, Amrik; Dutta, Tanmay; Nain, Lata; Khare, Sunil K.

Synthesis, SAR and docking studies of substituted aryl phenylthiazolyl phenylcarboxamide as potential protein tyrosine phosphatase 1B (PTP1B) inhibitors

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-06-05

OAAI

Varshney, Kanika; Gupta, Amit K.; Rawat, Arun; Srivastava, Rohit; Mishra, Akansha; Saxena, Mridula; Srivastava, Arvind K.; Jain, Sudha; Saxena, Anil K.

Multi-target, ensemble-based virtual screening yields novel allosteric KRAS inhibitors at high success rate 多靶点，基于集合的虚拟筛选以高成功率产生新型变构KRAS抑制剂

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-04-29

PREAI

Gupta, Amit K.; Wang, Xu; Pagba, Cynthia V.; Prakash, Priyanka; Sarkar-Banerjee, Suparna; Putkey, John; Gorfe, Alemayehu A.

Discovery of High-Affinity Noncovalent Allosteric KRAS Inhibitors That Disrupt Effector Binding 发现破坏效应子结合的高亲和力非共价变构KRAS抑制剂

ACS OMEGA

IF4.3

2019-02-08

OAAI

McCarthy, Michael J.; Pagba, Cynthia V.; Prakash, Priyanka; Naji, Ali K.; van der Hoeven, Dharini; Liang, Hong; Gupta, Amit K.; Zhou, Yong; Cho, Kwang-Jin; Hancock, John F.; Gorfe, Alemayehu A.

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-02-03

PREAI

Tantry, Subramanyam J.; Markad, Shankar D.; Shinde, Vikas; Bhat, Jyothi; Balakrishnan, Gayathri; Gupta, Amit K.; Ambady, Anisha; Raichurkar, Anandkumar; Kedari, Chaitanyakumar; Sharma, Sreevalli; Mudugal, Naina V.; Narayan, Ashwini; Kumar, C. N. Naveen; Nanduri, Robert; Bharath, Sowmya; Reddy, Jitendar; Panduga, Vijender; Prabhakar, K. R.; Kandaswamy, Karthikeyan; Saralaya, Ramanatha; Kaur, Parvinder; Dinesh, Neela; Guptha, Supreeth; Rich, Kirsty; Murray, David; Plant, Helen; Preston, Marian; Ashton, Helen; Plant, Darren; Walsh, Jarrod; Alcock, Peter; Naylor, Kathryn; Collier, Matthew; Whiteaker, James; McLaughlin, Robert E.; Mallya, Meenakshi; Panda, Manoranjan; Rudrapatna, Suresh; Ramachandran, Vasanthi; Shandil, Radha; Sambandamurthy, Vasan K.; Mdluli, Khisi; Cooper, Christopher B.; Rubin, Harvey; Yano, Takahiro; Iyer, Pravin; Narayanan, Shridhar; Kavanagh, Stefan; Mukherjee, Kakoli; Balasubramanian, V.; Hosagrahara, Vinayak P.; Solapure, Suresh; Ravishankar, Sudha; Hameed, Shahul P.

Multi-Conformer Hierarchical Virtual Screening Workflow to Identify Potential K-Ras Inhibitors

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Gupta, Amit K.; Prakash, Priyanka; Putkey, John A.; Gorfe, Alemayehu A.

Identification of Novel Amino Acid Derived CCK-2R Antagonists As Potential Antiulcer Agent: Homology Modeling, Design, Synthesis, and Pharmacology

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2013-01-04

PREAI

Gupta, Amit K.; Varshney, Kanika; Singh, Neetu; Mishra, Vaibhav; Saxena, Mridula; Palit, Gautam; Saxena, Anil K.

Toward the Identification of a Reliable 3D QSAR Pharmacophore Model for the CCK2 Receptor Antagonism

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2012-05-04

PREAI

Gupta, Amit K.; Varshney, Kanika; Saxena, Anil K.

Identification of Novel S-Adenosyl-L-Homocysteine Hydrolase Inhibitors through Homology-Model-Based Virtual Screening, Synthesis, and Biological Evaluation

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2012-02-27

PREAI

Khare, Prashant; Gupta, Amit K.; Gajula, Praveen K.; Sunkari, Krishna Y.; Jaiswal, Anil K.; Das, Sanchita; Bajpai, Preeti; Chakraborty, Tushar K.; Dube, Anuradha; Saxena, Anil K.

Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

IF3.9

2011-06-01

PREAI

Gupta, Amit; Kumar, Anil; Kulkarni, S. K.

Pharmacophore Modeling of Substituted 1,2,4-Trioxanes for Quantitative Prediction of their Antimalarial Activity

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2010-07-27

PREAI

Gupta, Amit K.; Chakroborty, S.; Srivastava, Kumkum; Puri, Sunil K.; Saxena, Anil K.