Matthew H. Porteus - Publications, H-index & Citations

Matthew H. Porteus

stanford university school of medicine

72H指数

339论文数

2.4W被引数

收录论文 149

发表时间

Epigenetic landscape; key transcriptional regulators; and in vivo identification of human Tr1 cells 表观遗传景观；关键转录调控因子；以及人Tr1细胞在体内的鉴定

Science Advances

IF12.5

2026-07-10

OAAI

Alma-Martina Cepika; Laura Amaya; Colin Waichler; Mansi Narula; Michelle Mantilla; Benjamin C. Thomas; Pauline P. Chen; Robert A. Freeborn; Mara Pavel-Dinu; Jason Nideffer; Matthew Porteus; Rosa Bacchetta; Fabian Müller; William J. Greenleaf; Howard Y. Chang; Maria Grazia Roncarolo

Harmonizing standards and resources for the medical genome 调和医学基因组的标准与资源

Nature

IF48.5

2026-07-01

PREAI

Euan A. Ashley; Ash A. Alizadeh; Hanae Armitage; Ami S. Bhatt; Yair Blumenfeld; Andrew Carroll; R. Martin Chavez; Petros Giannikopoulos; Megan E. Grove; Meghan C. Halley; Kiran Khush; Niall J. Lennon; Samantha Maragh; Alexander Marson; Benedict Paten; Adam M. Phillippy; Matthew H. Porteus; Heidi L. Rehm; Bradley R. Ringeisen; Julia Salzman; Valerie A. Schneider; Fritz J. Sedlazeck; Lars M. Steinmetz; Fyodor D. Urnov; Stacia K. Wyman; Justin M. Zook; Lloyd B. Minor; Jennifer A. Doudna

Unveiling the cut-and-repair cycle of designer nucleases in human stem and T cells via CLEAR-time dPCR 通过清除时间dPCR揭示人类干细胞和T细胞中设计核酸酶的切割和修复周期

Nature Communications

IF15.7

2025-11-03

OAAI

Nathan White; John Alexander Chalk; Yi-Ting Hu; Samuel Mark Pins; Chinnu Rose Joseph; Panagiotis Antoniou; Sandra Wimberger; Stina Svensson; Soraia Patricia Caetano-Silva; Anne Charlotte Adriane Mudde; Rajeev Rai; Sridhar Selvaraj; William Nelson Feist; Marianna Romito; Grzegorz Sienski; Roberto Nitsch; Claire Booth; Giorgia Santilli; Alessia Cavazza; Matthew Hebden Porteus; Marcello Maresca; Adrian James Thrasher; Giandomenico Turchiano

IL10 gene mutations do not impair Tr1 differentiation in vivo and can be functionally corrected by precise gene editing

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Strubbe, Steven; Boss, Allison; Wang, Bing; Mantilla, Michelle Mercedes; Freeborn, Robert Arthur; Guevara Becerra, Martha; Gharahdaghi, Nima; Uhlig, Holm H.; Porteus, Matthew Hebden; Arkwright, Peter D.; Roncarolo, Maria-Grazia; Bacchetta, Rosa

Harnessing DNA Barcoding to enhance and sustain polyclonality in gene-edited hematopoietic stem cells 利用DNA条形码技术增强并维持基因编辑造血干细胞的异质性

Molecular Therapy Methods & Clinical Development

IF4.7

2025-10-16

OAAI

Isabel Ojeda-Perez; Andrés Bustos; Sridhar Selvaraj; Sara Fañanas-Baquero; Omaira Alberquilla-Fernandez; Luis-Javier Serrano; Jose Bonafont; Aida Garcia-Torralba; Raul Torres-Ruiz; Sandra Rodriguez-Perales; Valeri Lang; Cesar Trigueros; Rafael Mayo-Garcia; Oscar Quintana-Bustamante; Matthew Porteus; Rebeca Sánchez-Dominguez; Jose-Carlos Segovia

Overcoming Barriers to Commercially Pre-Viable Gene and Cell Therapies for Rare and Ultra-Rare Diseases 克服罕见病和超罕见病商业化前可行基因和细胞疗法的障碍

Molecular Therapy

IF12

2025-10-04

OAAI

David Barrett; Paula M. Cannon; Federico Mingozzi; Matthew Porteus; Isabelle Rivière; Terence R. Flotte

Global Observatory for Genome Editing Summit Statement: Call for a Charter on Emerging Technologies and Human Dignity 全球基因组编辑观察站峰会声明：呼吁制定关于新兴技术和人类尊严的宪章

crispr journal

IF0

2025-08-18

PREAI

; Françoise Baylis; John Evans; Timothy Hunt; J. Benjamin Hurlbut; Sheila Jasanoff; Douglas Kysar; Katherine Littler; Laurence Lwoff; Peter Mills; Jacob Moses; Matthew Porteus; Krishanu Saha; O. Carter Snead; Kaushik Sunder Rajan; David Winickoff; Carrie Wolinetz

Immune composition of the mononuclear cell fraction of human umbilical cord blood 人脐带血单核细胞组分中的免疫组成

Frontiers in Immunology

IF5.9

2025-08-02

OAAI

Karen Kikuta†; Esmond Lee†; Talia Menezes‡; Hannah Fung‡; Alvaro Amorin; Aditi Agrawal; Theodore L. Roth; Matthew Porteus

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery 在CAR T细胞中重新连接内源性基因以进行肿瘤限制性有效载荷递送

Nature

IF48.5

2025-07-02

OAAI

Amanda X. Y. Chen; Kah Min Yap; Joelle S. Kim; Kevin Sek; Yu-Kuan Huang; Phoebe A. Dunbar; Volker Wiebking; Jesse D. Armitage; Isabelle Munoz; Kirsten L. Todd; Emily B. Derrick; Dat Nguyen; Junming Tong; Cheok Weng Chan; Thang X. Hoang; Katherine M. Audsley; Marit J. van Elsas; Jim Middelburg; Joel N. Lee; Maria N. de Menezes; Thomas J. Cole; Jasmine Li; Christina Scheffler; Andrew M. Scott; Laura K. Mackay; Jason Waithman; Jane Oliaro; Simon J. Harrison; Ian A. Parish; Junyun Lai; Matthew H. Porteus; Imran G. House; Phillip K. Darcy; Paul A. Beavis

A Reset for Bioethics: A Statement from the Global Observatory for Genome Editing 《生物伦理学的重新设定：基因组编辑全球观察站的声明》

CRISPR JOURNAL

IF4

2025-05-21

PREAI

Sheila Jasanoff; J. Benjamin Hurlbut; Krishanu Saha; Jacob D. Moses; Daniel Affsprung; Henry Austin; Françoise Baylis; John H. Evans; Timothy Hunt; Douglas A. Kysar; Laurence Lwoff; Peter Mills; Jahnavi Phalkey; Matthew H. Porteus; O. Carter Snead; Kaushik Sunder Rajan; Carrie D. Wolinetz

Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes 人纹状体祖细胞含有可诱导的安全措施并过表达BDNF，可拯救亨廷顿病表型。

MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT

IF4.7

2025-03-01

OAAI

Simmons, Danielle A.; Selvaraj, Sridhar; Chen, Tingshuo; Cao, Gloria; Camelo, Talita Souto; Mchugh, Tyne L. M.; Gonzalez, Selena; Martin, Renata M.; Simanauskaite, Juste; Uchida, Nobuko; Porteus, Matthew H.; Longo, Frank M.

A differentiated β-globin gene replacement strategy uses heterologous introns to restore physiological expression 一种差异化的β-球蛋白基因替换策略利用异源内含子来恢复生理表达

MOLECULAR THERAPY

IF12

2025-02-01

OAAI

Wallace, Kirby A.; Gerstenberg, Trevor L.; Ennis, Craig L.; Perez-Bermejo, Juan A.; Partridge, James R.; Bandoro, Christopher; Matern, William M.; Andreoletti, Gaia; Krassovsky, Kristina; Kabir, Shaheen; Lalisan, Cassandra D.; Churi, Aishwarya R.; Chew, Glen M.; Corbo, Lana; Vincelette, Jon E.; Klasson, Timothy D.; Silva, Brian J.; Strukov, Yuri G.; Quejarro, B. Joy; Hill, Kaisle A.; Treusch, Sebastian; Grogan, Jane L.; Dever, Daniel P.; Porteus, Matthew H.; Wienert, Beeke

Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis 工程化合成信号受体以实现促红细胞生成素非依赖性红细胞生成

NATURE COMMUNICATIONS

IF15.7

2025-01-29

OAAI

Shah, Aadit P.; Majeti, Kiran R.; Ekman, Freja K.; Selvaraj, Sridhar; Sharma, Devesh; Sinha, Roshani; Soupene, Eric; Chati, Prathamesh; Luna, Sofia E.; Charlesworth, Carsten T.; Mccreary, Travis; Lesch, Benjamin J.; Tran, Tammy; Chu, Simon N.; Porteus, Matthew H.; Kyle Cromer, M.

TET2 regulates early and late transitions in exhausted CD8+ T cell differentiation and limits CAR T cell function

SCIENCE ADVANCES

IF12.5

2024-11-15

OAAI

Dimitri, Alexander J.; Baxter, Amy E.; Chen, Gregory M.; Hopkins, Caitlin R.; Rouin, Geoffrey T.; Huang, Hua; Kong, Weimin; Holliday, Christopher H.; Wiebking, Volker; Bartoszek, Robert; Drury, Sydney; Dalton, Katherine; Koucky, Owen M.; Chen, Zeyu; Giles, Josephine R.; Dils, Alexander T.; Jung, In-Young; O'Connor, Roddy; Collins, Sierra; Everett, John K.; Amses, Kevin; Sherrill-Mix, Scott; Chandra, Aditi; Goldman, Naomi; Vahedi, Golnaz; Jadlowsky, Julie K.; Young, Regina M.; Melenhorst, Jan Joseph; Maude, Shannon L.; Levine, Bruce L.; Frey, Noelle V.; Berger, Shelley L.; Grupp, Stephan A.; Porter, David L.; Herbst, Friederike; Porteus, Matthew H.; Carty, Shannon A.; Bushman, Frederic D.; Weber, Evan W.; Wherry, E. John; Jordan, Martha S.; Fraietta, Joseph A.

Enhancement of erythropoietic output by Cas9-mediated insertion of a natural variant in haematopoietic stem and progenitor cells 通过在造血干细胞和祖细胞中Cas9-mediated插入天然变体来增强红细胞生成输出

NATURE BIOMEDICAL ENGINEERING

IF26.6

2024-06-17

OAAI

Luna, Sofia E.; Camarena, Joab; Hampton, Jessica P.; Majeti, Kiran R.; Charlesworth, Carsten T.; Soupene, Eric; Selvaraj, Sridhar; Jia, Kun; Sheehan, Vivien A.; Cromer, M. Kyle; Porteus, Matthew H.

A Story of Perseverance: An Interview with Matthew Porteus

CRISPR JOURNAL

IF4

2024-06-01

PREAI

Porteus, Matthew H.; Davies, Kevin

Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF plus HOXA plus hematopoietic from pluripotent stem cells 谱系示踪体内造血干细胞起源，以有效地从多能干细胞中使人HLF加HOXA加造血

DEVELOPMENTAL CELL

IF8.7

2024-05-01

OAAI

Fowler, Jonas L.; Zheng, Sherry Li; Nguyen, Alana; Chen, Angela; Xiong, Xiaochen; Chai, Timothy; Chen, Julie Y.; Karigane, Daiki; Banuelos, Allison M.; Niizuma, Kouta; Kayamori, Kensuke; Nishimura, Toshinobu; Cromer, M. Kyle; Gonzalez-Perez, David; Mason, Charlotte; Liu, Daniel Dan; Yilmaz, Leyla; Miquerol, Lucile; Porteus, Matthew H.; Luca, Vincent C.; Majeti, Ravindra; Nakauchi, Hiromitsu; Red-Horse, Kristy; Weissman, Irving L.; Ang, Lay Teng; Loh, Kyle M.

Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency 基因校正的RAG2-SCID人造血干细胞恢复V(D)J-重组酶和拯救淋巴缺陷

BLOOD ADVANCES

IF7.1

2024-04-09

OAAI

Pavel-Dinu, Mara; Gardner, Cameron L.; Nakauchi, Yusuke; Kawai, Tomoki; Delmonte, Ottavia M.; Palterer, Boaz; Bosticardo, Marita; Pala, Francesca; Viel, Sebastien; Malech, Harry L.; Ghanim, Hana Y.; Bode, Nicole M.; Kurgan, Gavin L.; Detweiler, Angela M.; Vakulskas, Christopher A.; Neff, Norma F.; Sheikali, Adam; Menezes, Sherah T.; Chrobok, Jade; Gonzalez, Elaine M. Hernandez; Majeti, Ravindra; Notarangelo, Luigi D.; Porteus, Matthew H.

A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5-and CXCR4-tropic HIV-1 infection

CELL STEM CELL

IF20.4

2024-04-01

OAAI

Dudek, Amanda M.; Feist, William N.; Sasu, Elena J.; Luna, Sofia E.; Ben-Efraim, Kaya; Bak, Rasmus O.; Cepika, Alma -Martina; Porteus, Matthew H.

Investigating adverse genomic and regulatory changes caused by replacement of the full-length CFTR cDNA using Cas9 and AAV

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-03-01

OAAI

Vaidyanathan, Sriram; Kerschner, Jenny L.; Paranjapye, Alekh; Sinha, Vrishti; Lin, Brian; Bedrosian, Tracy A.; Thrasher, Adrian J.; Turchiano, Giandomenico; Harris, Ann; Porteus, Matthew H.

研究方向