Fangtian Fan

Bengbu Medical University

H指数:19

被引数:945

个人简介

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教育背景

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工作经历

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荣誉奖项

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Discovery of novel hydroxycamptothecin derivatives as potent Topo I inhibitors for antitumor guided by molecular dynamics

基于分子动力学的抗肿瘤新型羟基喜树碱衍生物作为强效拓扑异构酶I抑制剂的发现

European Journal of Medicinal Chemistry

IF5.9

2026-07-010

PRE

Dexmedetomidine regulates fatty acid oxidation through the AMPK/PGC-1α/CPT1A pathway to mitigate renal ischaemia-reperfusion injury

右美托咪定通过AMPK/PGC-1α/CPT1A通路调节脂肪酸氧化以减轻肾缺血再灌注损伤

Toxicology and Applied Pharmacology

IF3.4

2026-02-190

PRE

OTSSP167 suppresses TNBC brain metastasis via ROS-driven P38/JNK and FAK/ERK pathways

OTSSP167通过ROS驱动的P38/JNK和FAK/ERK通路抑制三阴性乳腺癌脑转移

European Journal of Pharmacology

IF4.7

2025-07-290

Halofuginone targets Serine/Glycine synthesis to reverse epidermal growth factor receptor Tyrosine Kinase inhibitor resistance in lung adenocarcinoma

盐酸羟氯喹通过靶向丝氨酸/甘氨酸合成来逆转肺腺癌中表皮生长因子受体酪氨酸激酶抑制剂的耐药性

PHYTOMEDICINE

IF8.3

2025-07-010

OAAI

Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis (vol 20, 28, 2023)

JOURNAL OF INFLAMMATION-LONDON

IF4.1

2025-02-170

OAAI

Experimental study on the inhibitory effect of Halofuginone on NSCLC

卤夫酮对非小细胞肺癌抑制作用的实验研究

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2025-02-010

OAAI

Inflammatory and Immune Mechanisms in COPD: Current Status and Therapeutic Prospects

inflammation research

IF4.1

2024-09-010

Natural pentacyclic triterpenoid from Pristimerin sensitizes p53-deficient tumor to PARP inhibitor by ubiquitination of Chk1

PHARMACOLOGICAL RESEARCH

IF10.5

2024-03-011

OAAI

Animal models of brain and spinal cord metastases of NSCLC established using a brain stereotactic instrument

HELIYON

IF3.6

2024-02-011

OAAI

Shenqi Fuzheng injection modulates tumor fatty acid metabolism to downregulate MDSCs infiltration, enhancing PD-L1 antibody inhibition of intracranial growth in Melanoma

PHYTOMEDICINE

IF8.3

2024-01-016

PRE

Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis

JOURNAL OF INFLAMMATION-LONDON

IF4.1

2023-08-217

OAAI

Experimental study of EGFR-TKI aumolertinib combined with ionizing radiation in EGFR mutated NSCLC brain metastases tumor

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2023-04-018

OAAI

Bullatacin triggers immunogenic cell death of colon cancer cells by activating endoplasmic reticulum chaperones

Bullatacin通过激活内质网伴侣蛋白触发结肠癌细胞的免疫原性细胞死亡

JOURNAL OF INFLAMMATION-LONDON

IF4.1

2021-06-1013

OAAI

4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2017-11-0117

PREAI

Nuclear PKM2 expression, an independent risk factor for ER after curative resection of hepatocellular carcinoma

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2016-12-019

PREAI

Candesartan attenuates angiogenesis in hepatocellular carcinoma via downregulating AT1R/VEGF pathway

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2016-10-0131

PREAI

Quercetin stimulates mitochondrial apoptosis dependent on activation of endoplasmic reticulum stress in hepatic stellate cells

PHARMACEUTICAL BIOLOGY

IF4.8

2016-08-3028

OAAI

G Cryptotanshinone, a Novel Tumor Angiogenesis Inhibitor, Destabilizes Tumor Necrosis Factor-α mRNA Via Decreasing Nuclear-Cytoplasmic Translocation of RNA-Binding Protein HuR

MOLECULAR CARCINOGENESIS

IF3.2

2015-08-2747

PREAI

The angiogenic responses induced by release of angiogenic proteins from tumor cell-activated platelets are regulated by distinct molecular pathways

IUBMB LIFE

IF3.2

2015-08-1821

OAAI

Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2015-08-0144

PREAI

Fangtian Fan

个人简介

教育背景

工作经历

荣誉奖项

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