Abdelsamed I. Elshamy - Publications, H-index & Citations

Abdelsamed I. Elshamy

National Research Centre

35H指数

195论文数

3.5K被引数

收录论文 78

发表时间

Self-nanoemulsifying drug delivery systems for enhanced anti-Salmonella bioactivity of Thymus vulgaris and Citrus reticulata essential oils: Optimization, characterization, and molecular docking 纳米自乳化药物递送系统用于增强迷迭香和柑橘精油对沙门氏菌的抗菌活性：优化、表征与分子对接

Journal of Drug Delivery Science and Technology

IF4.9

2026-06-22

PREAI

Abdulsalam M. Kassem; Asmaa A. Mahmoud; Fathalla Ayoob; Asmaa S. Mansour; Doaa D. Khalaf; Sherif E. Emam; Walid Anwar; Ibrahim A. Elbahwy; Mohamed F. Zidan; Ninh The Son; Le The Hoai; Abd El-Nasser G. El-Gendy; Abdelsamed I. Elshamy

Synergistic wound healing mechanisms of Heliotropium curassavicum extracts via redox modulation, inflammation suppression, and tissue remodeling: linking phytochemical diversity to antioxidant and anti-inflammatory effects Heliotorpium curassavicum提取物的协同伤口愈合机制：通过氧化还原调节、炎症抑制和组织重塑，将植物化学成分多样性与其抗氧化和抗炎作用联系起来

Inflammopharmacology

IF5.3

2026-02-16

OAAI

Rania F. Ahmed; Dalia M. Rasheed; Noha A. Mowaad; Rania Elgohary; Eman H. Eltantawy; Eman A. Negm; Mohamed A. Farag; Abdelsamed I. Elshamy

Investigation of Potent Anti-Mycobacterium tuberculosis Agents Derived from Pyridine Derivatives Targeting the Enoyl Acyl Carrier Protein Reductase (InhA): Design; Synthesis; and Computational Analysis 基于吡啶衍生物的强效抗Mycobacterium tuberculosis活性剂靶向烯酰酰基载体蛋白还原酶(InhA)的研究：设计、合成与计算分析

drug design; development and therapy

IF0

2026-01-08

OAAI

Ahmed Sabt; Małgorzata Korycka-Machala; Asmaa F Kassem; Ninh The Son; Nguyen Xuan Ha; Anna Brzostek; Mohamed G Thabit; Malwina Kawka; Bożena Dziadek; Abdelsamed I Elshamy; Ahmed M Atwa; Jarosław Dziadek

Comprehensive UHPLC-ESI-Orbitrap-MS Profiling and Bioactivity-Guided Fractionation of Euphorbia greenwayi: Mechanistic Insights Into Anti-Inflammatory and Antiaging Bioactive Metabolites 综合UHPLC-ESI-Orbitrap-MS分析及生物活性引导的Euphorbia greenwayi分离：抗炎和抗衰老生物活性代谢产物的机制见解

Biomedical Chromatography

IF1.7

2026-01-01

PREAI

Essa, Ahmed f.; Elghonemy, Mai m.; Abd elkarim, Asmaa s.; El-gendy, Zeinab a.; Ammar, Naglaa m.; Ibrahim, Reham s.; Ahmed, Rania f.; Farag, Mohamed a.; Elshamy, Abdelsamed i.

Metabolomic insights into anti-inflammatory, antipyretic, and antinociceptive properties of Ilex paraguariensis: A UPLC-MS/MS analysis of phytochemicals and metabolic pathways 代谢组学视角下巴拉圭茶（Ilex paraguariensis）的抗炎、解热和镇痛特性：植物化学物质和代谢通路的UPLC-MS/MS分析

Journal of Ethnopharmacology

IF5.4

2025-12-13

PREAI

Naglaa M. Ammar; Zeinab A. El-Gendy; Samar M. Bassam; Rania F. Ahmed; Sherif M. Afifi; Reda MS. Korany; Emad M. Hassan; Abd El-Nasser G. El-Gendy; Mohamed A. Farag; Abdelsamed I. Elshamy

Assessment of the therapeutic efficacy of rutin-loaded PLGA nanocapsule-based gel against imiquimod-induced psoriasis model using box-behnken design for optimization 基于PLGA纳米胶囊负载芦丁凝胶对咪喹莫特诱导的银屑病模型的治疗效果评估，并采用Box-Behnken设计进行优化

International Journal of Pharmaceutics

IF5.2

2025-12-11

PREAI

Rabab A. Husseini; Sherif E. Emam; Amal M. Abd El Razek; Eslam Hamed; Abdelsamed I. Elshamy; Dina M. Abdelnabi

An exploration of potent antileishmanial agents derived from quinoline–thiazole and thiadiazole hybrids; targeting DHFR-TS and PTR1: design; synthesis; and computational analyses 对源自喹啉–噻唑和噻二唑杂化物的强效抗利什曼原虫剂的探索；靶向DHFR-TS和PTR1：设计、合成和计算分析

RSC Med. Chem.

IF3.6

2025-11-19

PREAI

Huda R. M. Rashdan; Adnan A. Bekhit; Veronika Furlan; Kikuko Amagase; Abdelsamed I. Elshamy; Nourhan Elfar; Mohamed. R. Abdo; Tamer M. Ibrahim; Urban Bren; Wagdy M. Eldehna; Ahmed Sabt

Bioactive-rich Mangifera indica leaf extracts alleviate inflammation, pain, and fever via suppression of pro-inflammatory cytokines and activation of Nrf2 pathways 富含生物活性物质的Mangifera indica叶提取物通过抑制促炎细胞因子和激活Nrf2通路来缓解炎症、疼痛和发热。

Tissue and Cell

IF2.5

2025-11-18

PREAI

Mai M. Elghonemy; Amira R. Khattab; Mohamed F. Abdelhameed; Rani F. Ahmed; Mona M. Eid; Alaa M. Ali; Elana Kysil; Ludger A. Wessjohann; Mahmoud I. Nassar; Mohamed A. Farag; Abdelsamed I. Elshamy

Essential oil from Acacia nilotica leaves: Integrated GC-MS/NMR profiling, antibacterial and antibiofilm assays, and computational evaluation of key constituents

Journal of Essential Oil Bearing Plants

IF1.8

2025-11-02

PREAI

Elshamy, Abdelsamed I.; Taher, Rehab F.; Eid, Mona M.; Shehabeldine, Amr M.; Abdelaziz, Amer M.; Khalaf, Doaa D.; El-Rashedy, Ahmed A.; El Gendy, Abd El-Nasser G.; Imagawa, Hiroshi; Elgorban, Abdallah M.; Abd-ElGawad, Ahmed M.

Geraniol-loaded nanoemulsion alginate promotes accelerated Wound healing via anti-inflammatory, antioxidant, and pro-regenerative mechanisms with deep dermal penetration and excellent biocompatibility 载香叶醇纳米乳藻酸盐通过抗炎、抗氧化和促再生机制促进加速伤口愈合，并具有深层真皮渗透性和优异的生物相容性。

Journal of Drug Delivery Science and Technology

IF4.9

2025-10-19

PREAI

Zeinab A. El-Gendy; Fathalla Ayoob; Naglaa M. Ammar; Sherif E. Emam; Abdulsalam M. Kassem; Mohamed A. El-Saied; Mawada Mohamed Ali; Abd El-Nasser G. El-Gendy; Abdelsamed I. Elshamy

Exploring the bioactive volatiles and antioxidant potential of Zygophyllum coccineum essential oil: GC-MS analysis and molecular docking insights 探索Zygophyllum coccineum精油中的生物活性挥发物及其抗氧化潜力：GC-MS分析和分子对接见解

JOURNAL OF ESSENTIAL OIL BEARING PLANTS

IF0

2025-09-03

PREAI

Ahmed, Rania F.; Taher, Rehab F.; Eid, Mona M.; Son, Ninh The; Ha, Nguyen Xuan; El Gendy, Abd El-Nasser G.; Kasai, Yusuke; Imagawa, Hiroshi; Elshamy, Abdelsamed I.; Abd-Elgawad, Ahmed M.; Elgorban, Abdallah M.

Discovery of N′-(1-(coumarin-3-yl)ethylidene)benzenesulfonohydrazide as a novel wound healing enhancer: synthesis; biological assessment; and molecular modeling N′-(1-(coumarin-3-yl)ethylidene)benzenesulfonohydrazide作为新型伤口愈合增强剂的发现：合成；生物评估；以及分子模拟

Frontiers in Chemistry

IF4.2

2025-08-08

OAAI

Eman F. Khaleel; Heba Abdelmegeed; Abdel-Razik H. Abdel-Razik; Manal S. Ebaid; Ninh The Son; Nguyen Xuan Ha; Hoda Atef Abdelsattar Ibrahim; Mohamed A. Abdelrahman; Abdelsamed I. Elshamy; Jarosław Dziadek; Ahmed Sabt; Wagdy M. Eldehna

Flavonoid-rich Deverra tortuosa extract mitigates ethanol-induced gastritis via modulation of cytokine networks, oxidative pathways, and mucosal immunotoxicity 富含黄酮类化合物的Deverra tortuosa提取物通过调节细胞因子网络、氧化途径和黏膜免疫毒性，减轻乙醇诱导的胃炎。

tissue cell

IF0

2025-07-31

PREAI

Mohamed F. Abdelhameed; Mosab Gad; Heba A.S. El-Nashar; Rehab F. Taher; Rehab F. Abdel-Rahman; Asmaa S. Abd Elkarim; Alaa M. Ali; Mohamed A. Farag; Abdelsamed I. Elshamy

Exploring antitubercular activity of new coumarin derivatives targeting enoyl acyl carrier protein reductase (InhA): Synthesis, biological evaluation and computational studies

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2025-07-04

PREAI

Ebaid, Manal S.; Korycka-Machala, Malgorzata; Shaldam, Moataz A.; Thabit, Mohamed G.; Kawka, Malwina; Dziadek, Bozena; Kuziola, Magdalena; Ibrahim, Hoda Atef Abdelsattar; Lei, Xinsheng; Elshamy, Abdelsamed I.; Dziadek, Jaroslaw; Sabt, Ahmed

Rutin-loaded fast-dissolving sublingual niosomal film: Design, characterization, hepatoprotective potential, and pharmacokinetic evaluation in ceftriaxone-induced liver injury in rats 芦丁负载的快速溶解舌下niosomal薄膜：设计、表征、对头孢曲松诱导的大鼠肝损伤的保肝潜力及药代动力学评价

Journal of Drug Delivery Science and Technology

IF4.9

2025-06-27

PREAI

Rabab A. Husseini; Mahran Mohamed Abd El-Emam; Sherif E. Emam; Eslam Hamed; Abdelsamed I. Elshamy; Dina M. Abdelnabi

Undescribed diterpenes from Euphorbia mauritanica L. as modulators of the breast cancer resistance: Mechanistic and in silico studies

PHYTOCHEMISTRY

IF3.4

2025-06-01

PREAI

Essa, Ahmed F.; Elghonemy, Mai M.; Taher, Rehab F.; Allam, Rasha M.; Elshamy, Abdelsamed I.

Synthesis and mechanistic insights of Coumarinyl-Indolinone hybrids as potent inhibitors of Leishmania major

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-04-01

PREAI

Batran, Rasha Z.; Ebaid, Manal S.; Nasralla, Sherry N.; Son, Ninh The; Ha, Nguyen Xuan; Ibrahim, Hoda Atef Abdelsattar; Alkabbani, Mahmoud Abdelrahman; Kasai, Yusuke; Imagawa, Hiroshi; Al-Sanea, Mohammad M.; Ibrahim, Tamer M.; Elshamy, Abdelsamed I.; Bekhit, Adnan A.; Eldehna, Wagdy M.; Sabt, Ahmed

Protective effects of Euphorbia heterophylla against testicular degeneration in streptozotocin-induced diabetic rats in relation to phytochemical profile (vol 20, e0314781, 2025)黄花杨梅对链脲佐菌素诱导的糖尿病大鼠睾丸退行性变的保护作用及其与植物化学成分谱的关系（卷 20，e0314781，2025）

PLOS ONE

IF2.6

2025-04-01

OAAI

Nagy, Ahmed M.; Fahmy, Heba A.; Abdel-Hameed, Mohamed F.; Taher, Rehab F.; Ali, Alaa M.; Amin, Mohamed M.; Afifi, Sherif M.; Esatbeyoglu, Tuba; Farag, Mohamed A.; Elshamy, Abdelsamed I.

Myricetin-loaded SBA-15 silica nanoparticles for enhanced management of pyrexia, pain, and inflammation through modulation of MAPK/NF-κB and COX-2/PGE-2 pathways: Evidence from the biochemical, histological, and metabolomic analysis

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2024-12-01

PREAI

El-Gendy, Zeinab A.; Ammar, Naglaa M.; Kassem, Abdulsalam M.; Attia, Mohamed S.; Afifi, Sherif M.; Ibrahim, Ahmed H.; Emam, Sherif E.; Korany, Reda M. S.; El-Gendy, Abd El-Nasser G.; Elshamy, Abdelsamed I.

Acaciasaligna extract alleviates quetiapine-induced sexual toxicity in male albino rats: Insights from UPLC-MS/MS metabolite profiling, structural and PI3K/NF- κ B pathway assessments

HELIYON

IF3.6

2024-07-01

OAAI

Yousof, Shimaa Mohammad; Shehata, Shaimaa A.; Ismail, Ezzat A.; Abd El-moneam, Samar M.; Mansour, Basma S. A.; Farag, Mohamed A.; Elshamy, Abdelsamed I.; El Gendy, Abd El-Nasser G.; Abd El-Fadeal, Noha M.; Serag, Ahmed; Abdel-Karim, Rehab Ibrahim; Mostafa, Mostafa M.; El-Sheikh, Dina H.; Zayed, Mohamed A.

研究方向