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G

Gregory L. Moore

xencor, inc.
H指数:19
被引数:1,741

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A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability

一项基于实验亲和力与可开发性的模拟抗体发现的盲法前瞻性基准研究

Nature Biotechnology
IF41.7
2026-08-190
OA
M. Frank Erasmus; Daniel Bedinger; Elizabeth Hopkins; Ginger Ferguson; Justine Strickler; Christilyn P. Graff; Samantha R. Summers; Stacy L. Capehart; Joshua D. Slocum; Crystal Richardson; Sumit Kumar; Zhifei Sun; Yujie Shang; Jixian Zhang; Ming Gu; Lixia Yi; Alon Wellner; Shuangjia Zheng; Wei Lu; Pietro Sormanni; Matthew Greenig; Haiping Zhang; Brendan T. Mann; Mahdi Baghbanzadeh; Ali Rahnavard; Gregory L. Moore; Huaiyu Sun; Ying Ding; Alex Nisthal; Jitendra Kanodia; Matthew J. Bernett; Aurélien Pélissier; Yanjun Shao; Maria Rodriguez Martinez; Karthik Ramesh; Horacio Nastri; Andreas Evers; Anhar Abdelatif; Andrew J. Bordner; Mykola Bordyuh; Lim Heo; Brian A. Kidd; H. Serhat Tetikol; Shuai Wei; Jung-Eun Shin; Ryan Peckner; Leigh Manley; Ajitesh Lunge; Yashas Devasurmutt; Bora Guloglu; Liviu Copoiu; Miles McGibbon; Monica L. Fernandez-Quintero; Nitesh Mishra; Sean M. Callaghan; Olivia M. Swanson; Daniel L. V. Bader; James A. Ferguson; Sai S. R. Raghavan; Benjamin Nemoz; Colleen A. Maillie; Charles Bowman; Bryan Briney; Andrew B. Ward; Paolo Marcatili; Rahmad Akbar; Bing He; Fandi Wu; Jianhua Yao; Bin Hu; Michal Kucer; Kaetlyn Rose Gibson; Rahul Somasundaram; Li-Wei Hung; Tomasz Kaszuba; Daved H. Fremont; Hyeongsun Jeong; Vinodh Babu Kurella; Shipra Malhotra; Satyendra Kumar; Yanyun Liu; Lingling Xu; Joshua Misa; Alexander Nicholas St. John; Jeff Vogt; Fátima A. Dávila-Hernández; Da Xu; Michael Chungyoun; Zyaja D. Huggan; Jeffrey J. Gray; Jonathan Parkinson; Young Su Ko; Wei Wang; Franziska Geiger; Jonathon D. Ziegler; Nikhil Haas; Chance Challacombe; Ahmad Qamar; Akshita Singh; Yi-Ching Tang; Zhiqiang An; Xiaoqian Jiang; Yejin Kim; Xinyan Zhao; Erik Swanson; Jürgen Klattig; Karsten Winkler; Tschimegma Bataa; Volker Sandig; Lilian Denzler; Chunan Liu; Randall J. Brezski; Laura Spector; Katheryn Perea-Schmittle; Sara D’Angelo; Fortunato Ferrara; Andrew R. M. Bradbury
A B7-H3-Targeted CD28 Bispecific Antibody Enhances the Activity of Anti-PD-1 and CD3 T-cell Engager Immunotherapies
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-11-061
OAAI
Moore, Gregory L.; Zeng, Veronica G.; Diaz, Juan E.; Bonzon, Christine; Avery, Kendra N.; Rashid, Rumana; Qi, Jing; Nam, Dong Hyun; Jacinto, Jonathan; Dragovich, Matthew A.; Kim, Yoon Kyung; Balcazar, Karen P.; Bakhit, Charles G.; Eivazi, Araz; Nguyen, Hanh; Muchhal, Umesh S.; Szymkowski, David E.; Desjarlais, John R.; Hedvat, Michael
JNJ-87801493 (CD20xCD28), a Potential First-in-Class CD20 Targeted CD28 Costimulatory Bispecific Antibody, Enhances the Activity of B-Cell Targeting T-Cell Engagers in Preclinical Models

JNJ-87801493 (CD20xCD28)，一种潜在的首创CD20靶向CD28共刺激双特异性抗体，增强了B细胞靶向T细胞结合剂在预临床模型中的活性。

BLOOD
IF23.1
2024-11-050
PRE
Fontan, Lorena; Zwolak, Adam; Guimerans-Lorenzo, Irene; Bekkers, Mariette; Hein, Nicholas; Vloemans, Nele; Trella, Emanuele; Smets, Tina; Cornelissen, Ivo; Assefa, Alemu; Verbist, Bie; Amorim, Ricardo; Seth, Pankaj; Dash, Ranjeet Prasad; Luistro, Leopoldo; Mattson, Bethany; Dragovich, Matthew A.; Hedvat, Michael; Moore, Gregory L.; Desjarlais, John R.; Kutlu, Olivia; Erhardt, Joseph; Philippar, Ulrike
Tumor-specific CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Dragovich, Matthew A.; Davra, Viralkumar; Faber, Matthew S.; Kim, Yoon Kyung; Nisthal, Alex; Zeng, Veronica G.; Jacinto, Jonathan; Diaz, Juan E.; Truong, Thuy; Qi, Jing; Avery, Kendra N.; Rashid, Rumana; Lee, Sung-Hyung; Chu, Seung Y.; Bonzon, Christine; Love, Ruschelle; Bernett, Matthew J.; Ernst, James A.; Bahjat, Rena; Barlow, Norman J.; Desjarlais, John R.; Hedvat, Michael; Moore, Gregory L.
AMG 509, A STEAP1 X CD3 BISPECIFIC XMAB® 2+1 IMMUNE THERAPY, EXHIBITS AVIDITY-DRIVEN BINDING AND PREFERENTIAL KILLING OF HIGH STEAP1-EXPRESSING PROSTATE AND EWING SARCOMA CANCER CELLS
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2020-11-092
PREAI
Li, Cong; Fort, Madeline; Liang, Lingming; Moore, Gregory; Bernett, Matthew; Muchhal, Umesh; Osgood, Tao; Yabut, Rodolfo; Kaliyaperumal, Sarav; Harrold, John; Canon, Jude; Rogojina, Anna; Kurmasheva, Raushan; Desjarlais, John; Houghton, Peter; Nolan-Stevaux, Olivier
Anti-SSTR2 x anti-CD3 bispecific antibody induces potent killing of human tumor cells in vitro and in mice, and stimulates target-dependent T cell activation in monkeys: A potential immunotherapy for neuroendocrine tumors
CANCER RESEARCH
IF16.6
2017-07-0112
PRE
Lee, Sung-Hyung; Chu, Seung Y.; Rashid, Rumana; Phung, Sheryl; Leung, Irene W.; Muchhal, Umesh S.; Moore, Gregory L.; Bernett, Matthew J.; Schubbert, Suzanne; Ardila, Connie; Bonzon, Christine; Foster, Paul; Szymkowski, David E.; Desjarlais, John R.
Immunotherapy with anti-PSMA x anti-CD3 bispecific antibody stimulates potent killing of a human prostate cancer cell line and target mediated T cell activation in monkeys: A potential therapy for prostate cancer
CANCER RESEARCH
IF16.6
2016-07-151
PRE
Chu, Seung Y.; Pong, Erik W. K.; Rashid, Rumana; Chen, Hsing; Chan, Emily W.; Phung, Sheryl; Endo, Nancy A.; Ardila, Maria C.; Bonzon, Christine; Leung, Irene W. L.; Muchhal, Umesh S.; Moore, Gregory L.; Bernett, Matthew J.; Desjarlais, John R.; Szymkowski, David E.
Immune suppression in cynomolgus monkeys by XPro9523 An improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRn

XPro9523对食蟹猴的免疫抑制作用与CD80，CD86和新生儿Fc受体FcRn的结合增强的CTLA4-Ig融合

MABS
IF7.3
2014-10-2726
OAAI
Bernett, Matthew J.; Chu, Seung Y.; Leung, Irene; Moore, Gregory L.; Lee, Sung-Hyung; Pong, Erik; Chen, Hsing; Phung, Sheryl; Muchhal, Umesh S.; Horton, Holly M.; Lazar, Greg A.; Desjarlais, John R.; Szymkowski, David E.

研究方向

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U
Umesh S. Muchhal
H 指数:23论文数:103被引数:2,570
J
John R. Desjarlais
H 指数:40论文数:189被引数:5,884
S
Seung Y. Chu
H 指数:21论文数:93被引数:1,829
M
Matthew J. Bernett
H 指数:18论文数:117被引数:1,627
R
Rumana Rashid
H 指数:23论文数:127被引数:2,602
C
Christine Bonzon
H 指数:14论文数:84被引数:2,817
K
Kendra N. Avery
H 指数:9论文数:71被引数:688
I
Irene Leung
H 指数:15论文数:52被引数:1,624
C
Costas D. Maranas
H 指数:82论文数:379被引数:2.1万
A
Alex Nisthal
H 指数:9论文数:25被引数:773