Vicente J. Arán - Publications, H-index & Citations

Vicente J. Arán

instituto de química médica

32H指数

173论文数

3.3K被引数

收录论文 49

发表时间

Dry Selection and Wet Evaluation of New 1,2-Disubstituted Nitroindazolin-3-One Derivatives as Promising Agents Against Trypanosoma cruzi 干法筛选和湿法评价新型1,2-二取代硝基吲唑烷-3-酮衍生物作为抗克氏锥虫的潜在药物

Pharmaceuticals

IF4.8

2026-09-18

OAAI

Juan A. Castillo-Garit; Josue Pozo-Martinez; Esteban Rocha-Valderrama; Cristian Rojas-Peña; Karen Acosta-Quiroga; Vicente J. Arán; Claudio Olea-Azar; Gerardo M. Casañola-Martin; Bakhtiyor Rasulev; Francisco Torrens; Facundo Pérez-Giménez; Mauricio Moncada-Basualto

Computational Investigation of the Potential Antileishmanial Mechanism of the Nitroindazole Derivative VATR131 硝基吲唑衍生物VATR131潜在的抗利什曼原虫机制的计算机模拟研究

Pharmaceuticals 2025, Vol. 18, Page 1489

IF4.8

2025-10-03

OAAI

Omar Casanova-Alvarez; Niurka Mollineda-Diogo; Aliuska Morales-Helguera; Vicente Arán-Redó; Reinaldo Molina-Ruiz; Norberto Sánchez-Cruz; Yendrek Velásquez-López; Yunierkis Perez-Castillo

Antimalarial Quinoline Drugs Inhibit β-Hematin and Increase Free Hemin Catalyzing Peroxidative Reactions and Inhibition of Cysteine Proteases

SCIENTIFIC REPORTS

IF3.9

2019-10-28

OAAI

Herraiz, Tomas; Guillen, Hugo; Gonzalez-Pena, Diana; Aran, Vicente J.

Synthesis and Biological in vitro and in vivo Evaluation of 2-(5-Nitroindazol-1-yl)ethylamines and Related Compounds as Potential Therapeutic Alternatives for Chagas Disease

CHEMMEDCHEM

IF3.4

2018-09-04

OAAI

Martin-Escolano, Ruben; Aguilera-Venegas, Benjamin; Marin, Clotilde; Martin-Montes, Alvaro; Martin-Escolano, Javier; Medina-Carmona, Encarnacion; Aran, Vicente J.; Sanchez-Moreno, Manuel

Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines

CHEMMEDCHEM

IF3.4

2018-05-22

OAAI

Fonseca-Berzal, Cristina; Ibanez-Escribano, Alexandra; Vela, Nerea; Cumella, Jose; Jose Nogal-Ruiz, Juan; Antonio Escario, Jose; Bernardino da Silva, Patricia; Meuser Batista, Marcos; Soeiro, Maria de Nazare C.; Sifontes-Rodriguez, Sergio; Meneses-Marcel, Alfredo; Gomez-Barrio, Alicia; Aran, Vicente J.

Identification, occurrence and activity of quinazoline alkaloids in Peganum harmala

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2017-05-01

PREAI

Herraiz, Tomas; Guillen, Hugo; Aran, Vicente J.; Salgado, Antonio

Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-06-01

PREAI

Fonseca-Berzal, Cristina; Ibanez-Escribano, Alexandra; Reviriego, Felipe; Cumella, Jose; Morales, Paula; Jagerovic, Nadine; Nogal-Ruiz, Juan Jose; Escario, Jose Antonio; da Silva, Patricia Bernardino; Soeiro, Maria de Nazare C.; Gomez-Barrio, Alicia; Aran, Vicente J.

Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-04-01

PREAI

Ibanez-Escribano, Alexandra; Reviriego, Felipe; Nogal-Ruiz, Juan Jose; Meneses-Marcel, Alfredo; Gomez-Barrio, Alicia; Escario, Jose Antonio; Aran, Vicente J.

Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2014-09-01

PREAI

Palmeiro-Roldan, Ricardo; Fonseca-Berzal, Cristina; Gomez-Barrio, Alicia; Aran, Vicente J.; Escario, Jose A.; Torrado-Duran, Susana; Torrado-Santiago, Santiago

New perspectives on the synthesis and antichagasic activity of 3-alkoxy-1-alkyl-5-nitroindazoles

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-03-01

PREAI

Muro, Beatriz; Reviriego, Felipe; Navarro, Filar; Marin, Clotilde; Ramirez-Macias, Inmaculada; Jose Rosales, Maria; Sanchez-Moreno, Manuel; Aran, Vicente J.

Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2014-03-01

PREAI

Martins Alho, Miriam A.; Marrero-Ponce, Yovani; Barigye, Stephen J.; Meneses-Marcel, Alfredo; Tugores, Yanetsy Machado; Montero-Torres, Alina; Gomez-Barrio, Alicia; Nogal, Juan J.; Garcia-Sanchez, Rory N.; Celeste Vega, Maria; Rolon, Miriam; Martinez-Fernandez, Antonio R.; Escario, Jose A.; Perez-Gimenez, Facundo; Garcia-Domenech, Ramon; Rivera, Norma; Mondragon, Ricardo; Mondragon, Mnica; Ibarra-Velarde, Froylan; Lopez-Arencibia, Atteneri; Martin-Navarro, Carmen; Lorenzo-Morales, Jacob; Gabriela Cabrera-Serra, Maria; Pinero, Jose; Tytgat, Jan; Chicharrom, Roberto; Aran, Vicente J.

Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-02-01

PREAI

Gonzalez-Naranjo, Pedro; Perez-Macias, Natalia; Campillo, Nuria E.; Perez, Concepcion; Aran, Vicente J.; Giron, Rocio; Sanchez-Robles, Eva; Isabel Martin, Maria; Gomez-Canas, Maria; Garcia-Arencibia, Moises; Fernandez-Ruiz, Javier; Paez, Juan A.

Indazoles: a new top seed structure in the search of efficient drugs against Trypanosoma cruzi

FUTURE MEDICINAL CHEMISTRY

IF3.4

2013-10-21

PREAI

Aguilera-Venegas, Benjamin; Olea-Azar, Claudio; Aran, Vicente J.; Speisky, Hernan

Spectroelectrochemistry of 1,4-naphthoquinones and 5-nitroindazoles: Reduction mechanisms and free radical stability

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2013-09-01

PREAI

Pozo, B.; Aguilera-Venegas, B.; Olea-Azar, C.; Aran, V. J.; Salas, C. O.; Zuniga, M. C.

ESR study on the hyperfine structure of free radicals derived from 1,3-disubstituted-5-nitroindazoles and 1,4-disubstituted-7-nitroquinoxalin-2-ones

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2013-09-01

PREAI

Zarate, I.; Aguilera-Venegas, B.; Olea-Azar, C.; Aran, V. J.

1,3-Disubstituted-5-nitroindazole derivatives are inhibitors and subversive substrates of trypanothione reductase from Trypanosoma cruzi

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2013-09-01

PREAI

Aguilera-Venegas, B.; Olea-Azar, C.; Speisky, H.; Aran, A. V. J.; Krauth-Siegel, R. L.

Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2012-12-01

PREAI

Celeste Vega, Maria; Rolon, Miriam; Montero-Torres, Alina; Fonseca-Berzal, Cristina; Antonio Escario, Jose; Gomez-Barrio, Alicia; Galvez, Jorge; Marrero-Ponce, Yovani; Aran, Vicente J.

In vivo genotoxicity and cytotoxicity assessment of a novel quinoxalinone with trichomonacide activity

toxicology and applied pharmacology

IF2.8

2012-10-10

PREAI

Rivera, Norma; Rojas, Marcela; Zepeda, Armando; Malagon, Filiberto; Aran, Vicente J.; Marrero-Ponce, Yovani; Rivera, Ernesto; Fortoul, Teresa I.

Biological and chemical study of fused tri- and tetracyclic indazoles and analogues with important antiparasitic activity

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

IF4.6

2012-09-01

PREAI

Diaz-Urrutia, Christian A.; Olea-Azar, Claudio A.; Zapata, Gerald A.; Lapier, Michel; Mura, Francisco; Aguilera-Venegas, Benjamin; Aran, Vicente J.; Lopez-Munoz, Rodrigo A.; Maya, Juan D.

Discovery of novel anti-inflammatory drug-like compounds by aligning in silico and in vivo screening: The nitroindazolinone chemotype

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2011-12-01

PREAI

Marrero-Ponce, Yovani; Siverio-Mota, Dany; Galvez-Llompart, Maria; Recio, Maria C.; Giner, Rosa M.; Garcia-Domenech, Ramon; Torrens, Francisco; Aran, Vicente J.; Cordero-Maldonado, Maria Lorena; Esguera, Camila V.; de Witte, Peter A. M.; Crawford, Alexander D.

研究方向