Geny M. M. Groothuis - Publications, H-index & Citations

Geny M. M. Groothuis

University of Groningen

55H指数

243论文数

1.2W被引数

收录论文 71

发表时间

Significance of the Vitamin D Receptor on Crosstalk with Nuclear Receptors and Regulation of Enzymes and Transporters

AAPS JOURNAL

IF3.7

2022-06-01

PREAI

Noh, Keumhan; Chow, Edwin C. Y.; Quach, Holly P.; Groothuis, Geny M. M.; Tirona, Rommel G.; Pang, K. Sandy

Development of a Novel Ex-vivo 3D Model to Screen Amoebicidal Activity on Infected Tissue

SCIENTIFIC REPORTS

IF3.9

2019-06-10

OAAI

Elena Guzman-Delgado, Nancy; Edith Carranza-Torres, Irma; Garcia-Davis, Sara; Rivera, Gildardo; Moran-Martinez, Javier; Denys Betancourt-Martinez, Nadia; Groothuis, G. M. M.; de Graaf, I. A. M.; Carranza-Rosales, Pilar

Imaging of protein distribution in tissues using mass spectrometry: An interdisciplinary challenge

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

IF12

2019-03-01

OAAI

Han, Jiaying; Permentier, Hjalmar; Bischoff, Rainer; Groothuis, Geny; Casini, Angela; Horvatovich, Peter

Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin

BIOCONJUGATE CHEMISTRY

IF3.9

2018-10-31

OAAI

Han, Jiaying; Raeder, Andreas F. B.; Reichart, Florian; Aikman, Brech; Wenzel, Margot N.; Woods, Ben; Weinmueller, Michael; Ludwig, Beatrice S.; Sturup, Stefan; Groothuis, Geny M. M.; Permentier, Hjalmar P.; Bischoff, Rainer; Kessler, Horst; Horvatovich, Peter; Casini, Angela

Human and rat precision-cut intestinal slices as ex vivo models to study bile acid uptake by the apical sodium-dependent bile acid transporter

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2018-08-01

OAAI

Li, Ming; Vokral, Ivan; Evers, Bernard; de Graaf, Inge A. M.; de Jager, Marina H.; Groothuis, Geny M. M.

Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs (vol 115, pg 175, 2018)

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2018-05-01

OAAI

Notenboom, Sylvia; Weigand, Karl M.; Proost, Johannes H.; van Lipzig, Marola M.; van de Steeg, Evita; van den Broek, Petra H. H.; Greupink, Rick; Russel, Frans G. M.; Groothuis, Geny M. M.

Differentiation of human-induced pluripotent stem cell under flow conditions to mature hepatocytes for liver tissue engineering 在流动条件下人诱导多能干细胞向成熟肝细胞的分化，用于肝组织工程

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

IF2.6

2018-04-06

OAAI

Starokozhko, Viktoriia; Hemmingsen, Mette; Larsen, Layla; Mohanty, Soumyaranjan; Merema, Marjolijn; Pimentel, Rodrigo C.; Wolff, Anders; Emneus, Jenny; Aspegren, Anders; Groothuis, Geny; Dufva, Martin

Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2018-03-01

OAAI

Notenboom, Sylvia; Weigand, Karl M.; Proost, Johannes H.; van Lipzig, Marola M. H.; van de Steeg, Evita; van den Broek, Petra H. H.; Greupink, Rick; Russel, Frans G. M.; Groothuis, Geny M. M.

Anticancer Gold N-Heterocyclic Carbene Complexes: A Comparative in vitro and ex vivo Study

CHEMMEDCHEM

IF3.4

2017-08-29

OAAI

Estrada-Ortiz, Natalia; Guarra, Federica; de Graaf, Inge A. M.; Marchetti, Lorella; de Jager, Marina H.; Groothuis, Geny M. M.; Gabbiani, Chiara; Casini, Angela

Challenges on the road to a multicellular bioartificial liver

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

IF2.6

2017-05-31

OAAI

Starokozhko, Viktoriia; Groothuis, Geny M. M.

Rat precision-cut liver slices predict drug-induced cholestatic injury

ARCHIVES OF TOXICOLOGY

IF6.9

2017-04-08

OAAI

Starokozhko, Viktoriia; Greupink, Rick; van de Broek, Petra; Soliman, Nashwa; Ghimire, Samiksha; de Graaf, Inge A. M.; Groothuis, Geny M. M.

Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days (vol 91, pg 2079, 2017)

ARCHIVES OF TOXICOLOGY

IF6.9

2016-11-30

OAAI

Starokozhko, Viktoriia; Vatakuti, Suresh; Schievink, Bauke; Merema, Marjolijn T.; Asplund, Annika; Synnergren, Jane; Aspegren, Anders; Groothuis, Geny M. M.

Judging the value of 'liver-on-a-chip' devices for prediction of toxicity 判断 “芯片上的肝脏” 设备对毒性预测的价值

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2016-10-18

OAAI

Starokozhko, Viktoriia; Groothuis, Geny M. M.

Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days

ARCHIVES OF TOXICOLOGY

IF6.9

2016-10-07

OAAI

Starokozhko, Viktoriia; Vatakuti, Suresh; Schievink, Bauke; Merema, Marjolijn T.; Asplund, Annika; Synnergren, Jane; Aspegren, Anders; Groothuis, Geny M. M.

Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach

ARCHIVES OF TOXICOLOGY

IF6.9

2016-06-25

OAAI

Vatakuti, Suresh; Olinga, Peter; Pennings, Jeroen L. A.; Groothuis, Geny M. M.

Translational Modeling in Schizophrenia: Predicting Human Dopamine D2 Receptor Occupancy (vol 33, pg 1003, 2016)

PHARMACEUTICAL RESEARCH

IF4.3

2016-03-10

OAAI

Johnson, Martin; Kozielska, Magdalena; Reddy, Venkatesh Pilla; Vermeulen, An; Barton, Hugh A.; Grimwood, Sarah; de Greef, Rik; Groothuis, Geny M. M.; Danhof, Meindert; Proost, Johannes H.

Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2016-03-09

OAAI

Vataltuti, Suresh; Pennings, Jeroen L. A.; Gore, Emilia; Olinga, Peter; Groothuis, Geny M. M.

Precision-cut intestinal slices: alternative model for drug transport, metabolism, and toxicology research

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2016-01-09

OAAI

Li, Ming; de Graaf, Inge A. M.; Groothuis, Geny M. M.

Translational Modeling in Schizophrenia: Predicting Human Dopamine D2 Receptor Occupancy

PHARMACEUTICAL RESEARCH

IF4.3

2015-12-30

OAAI

Johnson, Martin; Kozielska, Magdalena; Reddy, Venkatesh Pilla; Vermeulen, An; Barton, Hugh A.; Grimwood, Sarah; de Greef, Rik; Groothuis, Geny M. M.; Danhof, Meindert; Proost, Johannes H.

Influence of Inflammation on Voriconazole Metabolism

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2015-05-01

OAAI

Ventura, M. A. Encalada; Span, L. F. R.; van den Heuvel, E. R.; Groothuis, G. M. M.; Alffenaar, J. -W. C.

研究方向