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C

Cecilia M. Borghese

University of Texas at Austin

H指数:21

被引数:1,257

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Open-State Dynamics and Allosteric Modulation of the α1β3γ2 GABAA Receptor Stabilized by L9′T/S Substitutions

α1β3γ2 GABAA受体在L9′T/S替换稳定下的开态动力学与别构调节

Journal of Chemical Information and Modeling

IF5.3

2026-05-250

PRE

Putative RNA editing of a nicotinic receptor increases acetylcholine sensitivity

烟碱型受体假定的RNA编辑增加乙酰胆碱敏感性

Journal of General Physiology

IF2.9

2026-02-230

PRE

State-dependent energetics of GABAA receptor modulators

BIOPHYSICAL JOURNAL

IF3.1

2024-07-010

PRE

(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the 13(+)/a(-) interface near the TM2-TM3 loop

BIOCHEMICAL PHARMACOLOGY

IF5.6

2022-05-013

OAAI

Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-02-157

OA

Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes

SCIENTIFIC REPORTS

IF3.9

2017-07-248

OAAI

Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance

IF45.8

2017-01-010

OAAI

A Single Mutation in GLIC Reveals Both the Potentiating and the Inhibitory Nature of Propofol

BIOPHYSICAL JOURNAL

IF3.1

2016-02-010

OAAI

Identification of an Inhibitory Alcohol Binding Site in GABAaRho1

BIOPHYSICAL JOURNAL

IF3.1

2016-02-010

OAAI

Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors

ACS CHEMICAL NEUROSCIENCE

IF3.9

2015-11-2515

OA

Functional Validation of Virtual Screening for Novel Agents with General Anesthetic Action at Ligand-Gated Ion Channelss

MOLECULAR PHARMACOLOGY

IF3

2013-11-0120

OAAI

Mutations M287L and Q266I in the Glycine Receptor α1 Subunit Change Sensitivity to Volatile Anesthetics in Oocytes and Neurons, but Not the Minimal Alveolar Concentration in Knockin Mice

IF9.1

2012-10-017

OAAI

Characterization of Two Mutations, M287L and Q266I, in the α1 Glycine Receptor Subunit That Modify Sensitivity to Alcohols

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2012-02-0129

OAAI

Inhaled Anesthetic Responses of Recombinant Receptors and Knockin Mice Harboring α2(S270H/L277A) GABAA Receptor Subunits That Are Resistant to Isoflurane

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2011-01-0141

OAAI

Loss of Ethanol Conditioned Taste Aversion and Motor Stimulation in Knockin Mice with Ethanol-Insensitive α2-Containing GABAA Receptors

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2011-01-0155

OAAI

A Transmembrane Amino Acid in the GABAA Receptor β2 Subunit Critical for the Actions of Alcohols and Anesthetics

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2010-12-0128

OAAI

An isoflurane- and alcohol-insensitive mutant GABAA receptor α1 subunit with near-normal apparent affinity for GABA:: Characterization in heterologous systems and production of knockin mice

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2006-10-0166

PREAI

Knockin mice with ethanol-insensitive α1-containing γ-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2006-10-0156

PREAI

Mutation in neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes blocks ethanol action

ADDICTION BIOLOGY

IF2.6

2006-06-0915

PREAI

The δ subunit of γ-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2006-03-01160

PREAI